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ThRabis - VA Detailing Guide

This document presents information on a new 3-dose rabies vaccine called ThRabis. It notes that over 1.5 crore animal bite cases occur annually in India, with dog bites accounting for 91.5% of cases. The current standard rabies vaccine requires 5 doses over 28 days, but non-compliance is a major issue with 40% missing the 5th dose and 30% missing the 3rd dose. ThRabis is presented as the world's first 3-dose rabies vaccine that is compliant, compatible, and convenient compared to the 5-dose standard. Clinical trials demonstrated similar efficacy of ThRabis with 3 doses compared to the 5-dose reference vaccine. ThRabis induces both humoral

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Avanish Mishra
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131 views8 pages

ThRabis - VA Detailing Guide

This document presents information on a new 3-dose rabies vaccine called ThRabis. It notes that over 1.5 crore animal bite cases occur annually in India, with dog bites accounting for 91.5% of cases. The current standard rabies vaccine requires 5 doses over 28 days, but non-compliance is a major issue with 40% missing the 5th dose and 30% missing the 3rd dose. ThRabis is presented as the world's first 3-dose rabies vaccine that is compliant, compatible, and convenient compared to the 5-dose standard. Clinical trials demonstrated similar efficacy of ThRabis with 3 doses compared to the 5-dose reference vaccine. ThRabis induces both humoral

Uploaded by

Avanish Mishra
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Visual Aid Communication

VA Communication

Front Cover Page

Good Morning/ Afternoon/ Evening sir,


Doctor, I am ______ (your Name) representing Magfam
division of Cadila Pharma.

Doctor, as per reports, every year in India 1.5 Crore animal


bite cases are reported. Out of this, dog bite cases account as
high as 91.5% followed by cat, monkey & cow bite cases.

Current Anti-Rabies Vaccines are administered as 5 Dose


regime on Day0, Day3, Day7, Day14 & Day28 which takes
28days to complete the schedule.
Inner Page 1

Doctor, today Non-compliance to 5 dose vaccination schedule is a


major challenge.

(Point the graph)


Non-compliance to 5th Dose is 40% and to 3rd dose is 30%
India accounts for 60% of Asia’s & 35% of Global rabies death.

Moreover, reports suggest that more than one in every 3 patients


miss to complete 5 doses of Anti-Rabies Vaccine and are at risk of
Fatal Rabies.
Inner Page 2

Doctor, today Cadila- Magfam takes pride in introducing


World’s First 3 dose Anti Rabies Vaccine, ThRabis

Thrabis contains Recombinant Rabies G Protein 50 micrograms per


0.5 mL

One Two Tree .. Rabies Free

ThRabis is DCGI approved


ThRabis is Compliant, Compatible & Convenient
ThRabis is Globally patented and covered under Mediclaim without
hospitalization.

ThRabis comes in ready to inject formulation to be given on Day 0,


Day 3 & Day7
Inner Page 3

Doctor, World’s First 3 dose Anti Rabies Vaccine,


ThRabis is prepared using VLP platform technology (Virus Like
Particle) - A Recombinant subunit Nano particle vaccine

(Point the left side graph)


Doctor as per clinical trial published in Human Vaccines and
Immunotherapeutics, ThRabis demonstrates similar efficacy with 3
doses vs reference brand of 5 doses.

Doctor as shown in this graph, sero-protection with ThRabis on day 14


and 42 was same as that of 5 dose treated group.

(Point the right side graph)


Also, with Thrabis, lesser adverse events were reported compared to 5
dose treated group, as shown in this graph.
Inner Page 4

Doctor, ThRabis induces both humoral and cellular


immune response, provides improved antigen stability and
Immunogenicity

Besides, ThRabis has better safety and efficacy


Inner Page 5

Doctor, to prevent animal bite victims from rabies,


prescribe World’s First 3 dose Anti Rabies Vaccine,
ThRabis containing Recombinant Rabies G Protein 50 micrograms
per 0.5 mL
One Two Tree .. Rabies Free
ThRabis is Compliant, Compatible & Convenient

(Pointer on arrow head)


1. ThRabis offers Compliance of 3 doses compared to available 5
dose ARVs therefore prevents missing of dose and provides
assured protection from Rabies
2. ThRabis is Compatible – As ThRabis is Prepared by VLP
platform technology with Recombinant subunit Nano particles,
hence ThRabis offers better safety and efficacy
3. ThRabis is Convenient to use, as no reconstitution required
and is less painful. Therefore, ThRabis is doctor & patient friendly.
Back Page

Doctor, to prevent animal bite victims from rabies, prescribe World’s


First 3 dose Anti Rabies Vaccine - ThRabis containing Recombinant
Rabies G Protein 50 micrograms per 0.5 mL
One Two Tree .. Rabies Free

ThRabis is available as single dose vial for injection, to be


administered as IM
ThRabis comes in ready to inject formulation to be given on Day 0,
Day 3 & Day 7.

ThRabis is available in nearby chemist ______(name of


chemist/stockist)

Doctor requesting to protect animal bite victims visiting your clinic


with ThRabis, a Novel 3 Dose ARV

ThRabis is Compliant, Compatible & Convenient

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