Act Early with the Edwards FloTrac System

Shortens the Time from Assessment to Action

Optimize Fluid Balance and Monitor Cardiac Function in Your High-Risk Surgical Patients
Now, you have the insight you need to make critical decisions earlier and more efciently for your patients previously monitored with traditional vital signs alone. The FloTrac sensor, when used with the Vigileo monitor, provides continuous cardiac output (CCO/CCI), stroke volume (SV/SVI), stroke volume variation (SVV), and systemic vascular resistance (SVR/SVI)* through an existing arterial line. The FloTrac system is accurate, easy to use and less invasive: Connects to an existing arterial catheter Requires no manual calibration enabling rapid setup Automatically calculates key ow parameters every 20 seconds Continuously monitors changes in patients vascular tone (compliance and resistance) Validated against the clinical gold-standard Swan-Ganz pulmonary artery catheter1 In the very acute situation with rapid changes in vascular volume, blood pressure is probably not the optimal physiological variable to be measured, and indeed in some circumstances, relying on blood pressure alone may result in an increase in mortality. Bennett 2

FloTrac System Algorithm

CO = HR * SV

Measures pulse rate Beats identied by upslope of waveforms Pulse rate computed from 20 second time period of beats

Based upon the basic physiological principle that pulse pressure is proportional to stroke volume Utilizes statistical analysis to compute a robust assessment of PP characteristics Computed on a beat-by-beat basis

Compensates for differences in vascular tone Patient-to-patient differences estimated from demographic data Dynamic changes estimated by data and waveform analysis

pulse pressure is proportional to SV and is inversely related to aortic compliance.

Boulain et al3

Save Precious Time and Resources

The FloTrac system is easy to set up and use, providing real-time hemodynamic insight from pre-op to the operating room and to the ICU. And because the FloTrac system requires no additional catheters, boluses or chemical indicators, it will save you and your staff precious time and resources. Expand your options for monitoring high-risk patients: Guide uid optimization Assess real-time changes in vascular tone Guide inotropic therapy in real time Determine optimal cardiac pacing Optimize the effects of HR and SV Assess real-time effects of positive pressure ventilation Manage precise titration of cardiovascular medications

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Stroke Volume Variation and Fluid Optimization On Control Ventilated Patients

25 20

SVmax
15

SVmin

10

Airway Pressure Arterial Pressure

5 0

% SVV =
-5

SVmax-SVmin SVmean

1000

2000

3000

4000

5000

6000

7000

Expiration Controlled Ventilation

Inspiration Controlled Ventilation

The ability of the SVV variable to predict the responsiveness to such a small volume load and the continuous measurement of SVV and SV are of utmost clinical importance. . . . The receiver-operating curve (ROC) also demonstrated the superiority of SVV over SBP as a predictor of fluid responsiveness. Berkenstadt4 SVV values showed a significant correlation to changes in CI and therefore accurately predicted responsiveness to preload enhancement. Reuter et al5

The FloTrac System

The FloTrac system is engineered for usability by Edwards Lifesciences, the world leader in hemodynamic monitoring and originators of the Swan-Ganz pulmonary artery catheter. Providing new standards in ease of use, exibility and continuity of information, the FloTrac system is the next major advance in hemodynamic management.

FloTrac Sensor
FloTrac sensor is a less invasive hemodynamic monitoring device that, when used with the Vigileo monitor, continuously measures and displays key ow parameters. Cardiac output, stroke volume, stroke volume variation and SVR* are available using any standard arterial pressure line.

Vigileo Monitor
The Vigileo monitor allows for monitoring the balance of oxygen delivery and consumption on a minimally invasive platform the FloTrac sensor and the PreSep catheter.

PreSep Catheter
PreSep catheter is a triple lumen central venous oximetry catheter with an added capability for continuously monitoring central venous oxygen saturation (ScvO2). It is an integral part of Early Goal-Directed Therapy (EGDT)** for sepsis. The PreSep catheter provides central venous oxygen saturation monitoring, high ow rates for rapid uid administration, and convenient administration of therapeutic solutions.

To learn more about using the FloTrac system and to nd valuable educational resources, visit www.Edwards.com/FloTrac.

Any quotes used in this material are taken from independent third-party publications and are not intended to imply that such third party reviewed or endorsed any of the products of Edwards Lifesciences. Rx only. See package insert for full prescribing information. Edwards Lifesciences devices placed on the European market meeting the essential requirements referred to in Article 3 of the Medical Device Directive 93/42/EEC bear the CE marking of conformity. Edwards, FloTrac and Vigileo are trademarks of Edwards Lifesciences Corporation. Edwards Lifesciences, the stylized E logo, PreSep and SwanGanz are trademarks of Edwards Lifesciences Corporation and are registered in the US Patent and Trademark Ofce. * Derived with CVP. ** Early Goal-Directed Therapy and EGDT are trademarks of Dr. Emanuel Rivers. 2007 Edwards Lifesciences LLC. All rights reserved. AR02375

References: 1. A Manecke G, Auger W. Cardiac Output Determination From the Arterial Pressure Wave: Clinical Testing of a Novel Algorithm That Does Not Require Calibration. Journal of Cardiothoracic and Vascular Anesthesia 2007; Vol 21 (1): 3-7 2. Bennett D. Arterial Pressure: A Personal View. in M.R. Pinsky, D. Payen. Functional Hemodynamic Monitoring. Update In Intensive Care and Emergency Medicine 2005;42:89-97. 3. Boulain T, Achard JM, Teboul JL, et al. Changes in BP induced by passive leg raising predict response to uid loading in critically ill patients. Chest 2002;121(4):1245-52. 4. Berkenstadt H, Margalit N, Hadani M, et al. Stroke Volume Variation as a Predictor of Fluid Responsiveness in Patients Undergoing Brain Surgery. Anesthesia and Analgesia 2001;92:984-9. 5. Reuter DA, Felbinger TW, Schmidt C, et al. Stroke volume variations for assessment of cardiac responsiveness to volume loading in mechanically ventilated patients after cardiac surgery. Intensive Care Med 2002;28(4):392-8.

Edwards Lifesciences LLC One Edwards Way Irvine, CA 92614 USA 949.250.2500 800.424.3278 www.edwards.com Edwards Lifesciences (Canada) Inc. 1290 Central Pkwy West, Suite 300 Mississauga, Ontario Canada L5C 4R3 905.566.4220 800.268.3993 Edwards Lifesciences S.A. Ch. du Glapin 6 1162 Saint-Prex Switzerland 41.21.823.4300 Edwards Lifesciences Japan 2-8 Rokubancho Chiyoda-ku, Tokyo 102-0085 Japan 81.3.5213.5700 www.edwards.com/Japan