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sustain the protective levels of immunity as SARS-CoV-2 constantly mutates and with
the continuous emergence of newer variants that could evade host immunity [3,7,8]. The
emerging SARS-CoV-2 variants such as Delta, Omicron, and its lineages (variants of concern,
VOCs) have been found to cause significant adverse impacts by overpowering protective
immunity induced by COVID-19 vaccines and antibody-based therapies, resulting in
vaccine breakthrough infection, re-infection, and overall surging of cases and deaths
amid different waves of the ongoing pandemic. Therefore, efforts are being made to
develop more effective vaccines including variant-specific, mutation proof, universal next-
generation vaccines, as well as administering more doses of vaccines (booster shots) for
boosting protective immunity to safeguard health amid emerging variants [9–15]. Despite
the development of few vaccines and the ongoing global vaccination drive, COVID-19
vaccination hesitancy, diplomacy, and inequitable access to vaccines, particularly among
low- and middle-income countries, also constitute significant reasons for some hindrances
in the ongoing global vaccination drive, including booster shots, which helped in the
sustained global burden of COVID-19; hence, global vaccination coverage needs to be
enhanced holistically [16–21].
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Vaccines 2022, 10, 1929 5 of 9
Compared to previous methods such as manual content analysis and the word fre-
quency method, LDA topic modeling is the best fit for understanding the topics based
on which the corpus is built, particularly when dealing with unstructured data. Manual
content analysis was the first attempt to understand the determinants of perception in
textual data [33]. However, one of the significant drawbacks of manual content analysis is
that the entire process relies heavily on the expertise of the expert; therefore, the results
are unreliable. Next to manual content analysis, the word frequency model was used to
understand the determinants of perceptions in the textual data. The major drawback of this
method, however, is that the word frequency analysis method does not consider the word’s
context and is merely a representation of the word counts; therefore, the conclusions based
on this can often be confusing and ambiguous [34]. LDA is a standard method used by
many researchers because it employs a probabilistic framework to determine and detect
hidden themes and topics in the corpus by following the bag-of-words approach; therefore,
we employed LDA algorithms to understand the concerns Indian citizens discuss regarding
COVID-19 booster doses.
3. Results
This study was conducted in two parts. First, sentiment analysis was performed to
understand people’s sentiments towards booster doses of COVID-19 vaccines. Sentiment
analysis detects sentiments expressed by a person in a text. TextBlob algorithms examine
each word in the tweet and determine whether the general sentiment of the particular
text in the corpus is positive, negative, or neutral [35]. Second, LDA topic modeling was
utilized to identify the major aspects that Indian social media users discussed regarding
COVID-19 booster doses on social media. Topic Modeling is an assemblage of algorithms
that summarizes a massive corpus of texts by independently identifying obscure subjects
and themes covered by a collection of corpora. LDA adheres to the Bayesian principle,
where the algorithm considers that each text in the corpus is composed of a variety of
discrete topics, each of which has a multinomial word-frequency distribution [36–38]. A
total of 76,979 tweets were used in this study. We selected an equal number of tweets every
month in the corpus for an effective comparison. The sentiment analysis study revealed
that out of 76,979 tweets, more than half of the tweets (n = 40,719 tweets (52.8%)) about
COVID-19 booster doses had negative sentiments, 24,242 tweets (31.5%) showed neutral
sentiments, and 12,018 tweets (15.6%) had positive sentiments. The monthly distribution of
sentiments is presented in Table 1.
Graphical
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00
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Septem
March
March April
April May
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August ber
Total
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Positive
Positive 1409
1409 1572
1572 1417
1417 1680
1680 1945
1945 2058
2058 1937
1937
Neutral
Neutral 4754
4754 3736
3736 3057
3057 2699
2699 3612
3612 3057
3057 3327
3327
Negative
Negative 4834
4834 5689
5689 6523
6523 6618
6618 5440
5440 5882
5882 5733
5733
Months
Months(2022)
(2022)
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00
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March
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ber
Postitive
Postitive(%)
(%) 11.7
11.7 13
13 11.7
11.7 13.9
13.9 16.1
16.1 17.1
17.1 16.11
16.11
Neutral
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(%) 19.6
19.6 15.4
15.4 12.6
12.6 11.1
11.1 14.8
14.8 12.6
12.6 13.7
13.7
Negative
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(%) 11.8
11.8 13.9
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16 16.2
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14
Months
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(2022)
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Table
Table 2. Topic modeling.
Table 2.2.Topic
Topic modeling.
modeling.
4. Discussion
Our sentiment analysis showed that nearly 84.4% of Indians‘ social media posts on
the COVID-19 booster dose were either negative or neutral. A previous study analyzing
Indians’ perceptions regarding the first two doses of vaccines concluded that 17% of
the opinions of Indians regarding normal COVID-19 vaccines were negative and 47% of
opinions regarding normal COVID-19 vaccines were neutral [39]. There was an increase
of approximately 35% in the negative tone and a 16% decrease in the neutral tone. Our
results show that Indians’ opinions on booster doses are more negative and polarized than
the original normal COVID-19 vaccines. As shown in Figures 2 and 3, the percentage of
people posting about COVID-19 booster doses in a neutral sentiment fluctuated throughout
the time period. Compared to March 2022, the percentage of Indians positive for booster
doses increased slightly in the later months. Comparing with March, there is a considerable
reduction in the percentage of people posting about booster doses in a neutral sentiment. It
can be inferred from our results that when comparing to the initial months of 2022, Indians
have become more polarized in their opinion regarding the booster dose vaccines.
Our topic modeling results showed that certain aspects, such as feeling that there is
no need for young people to take booster doses, feeling that taking booster doses is not
healthy, skepticism towards big pharma companies, fear of illness, COVID-19 vaccines
not being trustworthy, feeling that normal doses of vaccines are enough, fear of severe
side effects, negative perceptions created by media regarding booster doses, fear of chest
pain, and feeling booster doses are unnecessary, are the concerns Indian citizens discuss
about COVID-19 booster doses. With only 15.6% of the population feeling positive about
booster doses, it will be difficult for Indian governments and health policymakers to
encourage more citizens to take up additional vaccines. The Indian governments and
policymakers should administer and promote effective awareness programs and policies
through social media and all forms of necessary communications to educate the Indian
public regarding the necessity of taking booster doses to achieve the desired results of
protective immunity among the population and safeguard their health amid the ongoing
COVID-19 pandemic under the threats of continuously emerging SARS-CoV-2 variants,
sub-variants, and lineages. This research has a few limitations. We analyzed the perceptions
of Indians regarding booster doses for a period of seven months. The results may vary
slightly across different periods. In our research, we also did not consider the aspect
of subculture that plays a role in individuals developing their perceptions of COVID-19
vaccines. Future research can analyze the aspect of subculture and how much it modifies or
influences an individual’s perception of the development of perception towards COVID-19
vaccines. Further, we have only used English tweets for this study, and so our results
analyzed only the perception of English-speaking people in India. Future research can
focus on understanding the difference in perception of Indians speaking various languages.
Author Contributions: Designed the study, P.S. and K.D.; made the first draft, J.M.L.; updated the
manuscript, R.I., C.C., D.V.S.K. and T.M.; reviewed and edited the final draft, K.D. All authors have
read and agreed to the published version of the manuscript.
Funding: This research received no external funding.
Institutional Review Board Statement: Not applicable.
Informed Consent Statement: Not applicable.
Data Availability Statement: Data are with corresponding author and will be provided upon rea-
sonable request.
Conflicts of Interest: The authors declare no conflict of interest.
Vaccines 2022, 10, 1929 8 of 9
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