SCIENCE 8 Q4 Weeks1to4 Binded Ver10-1
SCIENCE 8 Q4 Weeks1to4 Binded Ver10-1
SCIENCE 8 Q4 Weeks1to4 Binded Ver10-1
Science
Modules
Quarter 4 – Weeks 1 - 4
8
Science
Quarter 4 – Module 1
The Human Digestive Sytem
Science – Grade 8
Alternative Delivery Mode
Quarter 4 –Module 1: The Human Digestive System
Second Edition, 2021
Republic Act 8293, section 176 states that: No copyright shall subsist in any work of the
Government of the Philippines. However, prior approval of the government agency or office
wherein the work is created shall be necessary for exploitation of such work for profit. Such
agency or office may, among other things, impose as a condition the payment of royalties
Borrowed materials (i.e., songs, stories, poems, pictures, photos, brand names,
trademarks, etc.) included in this module are owned by their respective copyright holders. Every
effort has been exerted to locate and seek permission to use these materials from their
respective copyright owners. The publisher and authors do not represent nor claim ownership
over them.
Printed in the Philippines by the Schools Division Office of Makati City through the
support of the City Government of Makati (Local School Board)
1. Describe and give the functions of each organ of the digestive system;
2. Trace the pathway of food through the digestive tract; and
3. Explain how ingestion, absorption, assimilation, and excretion take place
through the interaction of the digestive system with the circulatory,
respiratory, and excretory system.
What I Know
1
Lesson
The Human Digestive System
1
WHY DO WE EAT? We eat food at breakfast, lunch and dinner, and sometimes in
between meals. WHY IS THIS NECESSARY? Animals get the nutrients they need by
taking in complex organic matter. WHAT IS THE IMPORTANCE OF FOOD WE EAT?
The body can only make use of the nutrients in the food after these nutrients have
passed through the cells in gut walls into the blood vessels. The blood in these blood
vessels will carry these nutrients to all parts of the body, where they will serve their
functions.
What’s In
In your previous year, you have been introduced to biological level of organization.
You were taught that the organism starts from the simplest to complex level.
Direction. Arrange the biological levels of organization from the simplest to the
most complex. Write the number inside the oval to indicate the correct sequence.
Start with 1 as the simplest and 5 as the most complex level.
ORGANISM ORGAN
TISSUE CELL ORGAN
SYSTEM
What’s New
2
DIGESTIVE ACCESSORY
TRACT ORGAN
2. GALL BLADDER B. It’s muscles mix the food with digestive juices and empties it’s
contents into the small intestine.
3
3. LARGE INTESTINE C. It is an opening through which all food enters the body.
What Is It
functions of the human digestive system. Let’s go into details as you read and
study the whole process of human digestion.
Digestion is a process of breaking down food into soluble molecules that can
be absorbed into the body. The Digestive System is involved in the process. In
humans, the two major parts of the Digestive System are the digestive tract and
accessory organs. The digestive tract serves as a passageway of food and
includes the mouth, esophagus, stomach, small intestine, and large intestine.
While the accessory organs are structures that do not directly act upon the food.
Salivary glands, liver, gall bladder, and pancreas are classified as accessory
organs.
Digestion starts in the mouth where the food is chewed and mixed. The
chemical breakdown of carbohydrates also begins in the mouth. Then the food is
swallowed and moves to the pharynx and passes to the esophagus. The
esophagus is about 25 cm long and 1.5 – 2 cm wide which propels food to the
stomach. In the stomach where digestion continues, food is mixed and churned
with gastric juices to form chyme. The chemical breakdown of proteins begins in
the stomach. From the stomach, the chyme will be received by the small
intestine. The small intestine is about 7 m long and 2.5vcm wide. It mixes
chyme with the digestives juices and propels food at a rate slow enough for
digestion and absorption. Fingerlike projections called villi increase the surface
area of the intestine and make absorption more efficient. Final digestion and
absorption take place in the small intestine. The undigested food materials that
become watery pass from the small intestine into the large intestine. The large
intestine or colon is about 1.5 m long and 6 cm wide. It absorbs water from the
undigested food it receives from the small intestine. When most of the water is
reabsorbed, solid waste, called feces is left. The feces move out of the body
through the anus.
4
https://pixabay.com/vectors/digestive-system-human- https://commons.wikimedia.org/wiki/File:Villi_
digestion-41529/ %26_microvilli_of_small_intestine.svg
The accessory organs have a specific role in digestion. The salivary glands
secrete saliva that lubricates the food and secretes an enzyme called ptyalin or
salivary amylase which changes starch to maltose. The liver produces bile which
emulsifies lipids. The gall bladder that is attached to the underside of the liver,
stores, and concentrates bile. The pancreas that lies behind the stomach secretes
pancreatic juice (mixture of digestive enzymes and sodium bicarbonate) into the
small intestine. The sodium bicarbonate neutralizes the acidic chyme coming from
the stomach.
The processes of human digestion include seven activities: ingestion,
propulsion, mechanical digestion, chemical digestion, absorption, assimilation,
and defecation.
1. Ingestion refers to the entry of food into the mouth. Food chewed in
the mouth, grinded by our teeth. Once inside your mouth, the food
turns into a moist lump called bolus. Enzymes present in the saliva
breakdown any starch.
2. Propulsion means the passage of food through the digestive tract. It
includes swallowing and peristalsis. Peristalsis is the wavelike
contraction and relaxation of the smooth muscles of the food tube. It
allows the movement of food down to the next part of the food tube.
3. Mechanical Digestion is mainly a physical process that does change
the chemical nature of the food instead it breakdowns food into a
smaller size. This includes mastication or chewing in the mouth,
churning of food in the stomach, and segmentation in the small
intestine.
4. Chemical Digestion involves the breakdown of complex food
molecules into their simplest form (building blocks) with the help of
enzymes. Each major food group uses different enzymes. Below
summarizes the chemical digestion of food.
carbohydrases
CARBOHYDRATES Simple sugars
protease
PROTEINS amino acids
5
5. Absorption is the movement of digested food molecules through the
wall of the food tube into the blood or lymph. This process takes place
primarily within the small intestine. From the surface cells of the food
tube, molecules of amino acids and simple sugars diffuse into the
capillaries and reach the blood. Molecules of fatty acids and glycerol
move into the lacteals and reach the lymph. At this point, the circulatory
system takes over the process.
6. Assimilation is the movement of digested food molecules into the
cells of the body where they are used. For instance, amino acids are
used to build new proteins, and glucose (a simple sugar) is used in
respiration to provide energy. The liver is important in assimilation
since it changes glucose into glycogen used for storage and amino
acids into proteins.
7. Defecation or egestion is the removal of undigested materials from the
body as feces. Feces are stored in the rectum and pass out through the
anus.
The digestive system absorbs water and nutrients from the food we eat.
The nutrients then are carried together with oxygen and water through the
circulatory system into cells throughout our body. Wastes from the cells are
eliminated through the respiratory system and excretory system.
What’s More
Answer:
6
Statement Mechanical Chemical
1. chewing food in
the mouth
2. fatty foods turn
into lipase
3. bread turns into
simple sugar
4 biting food into
smaller pieces
1. Meaty foods turn
into amino acids
What I Can Do
Activity 1.4 My Healthy Food Plate
Aside from observing the minimum public health standards, practicing good
nutrition is another way to combat the threat of COVID-19. In this activity, you will
create your healthy food plate using the food guide called Pinggang Pinoy. The
Pinggang Pinoy is a nutritional tool that will help you prepare healthy food on a per
meal basis.
Follow these Pinggang Pinoy guidelines as you build your own healthy eating
styles.
https://commons.wikimedia.org/wiki/File:0957jfOnse_San_Juan_Metro_Manilafvf_03.jpg
1. Make half your plate represents the Glow foods such as fruits and vegetables.
2. One-third of your plate consists of the Go foods like rice, corn, bread, and root
crops.
3. The remaining one-sixth of your plate must include Grow foods such as meat,
eggs, poultry, fish, beans, and legumes.
After your preparation, take a selfie with your own Healthy Food Plate and
submit it to your teacher via FB messenger or through your LMS.
7
References
Republic Act 8293, section 176 states that: No copyright shall subsist in any work of the
Government of the Philippines. However, prior approval of the government agency or office
wherein the work is created shall be necessary for exploitation of such work for profit. Such
agency or office may, among other things, impose as a condition the payment of royalties
Borrowed materials (i.e., songs, stories, poems, pictures, photos, brand names,
trademarks, etc.) included in this module are owned by their respective copyright holders. Every
effort has been exerted to locate and seek permission to use these materials from their
respective copyright owners. The publisher and authors do not represent nor claim ownership
over them.
Printed in the Philippines by the Schools Division Office of Makati City through the
support of the City Government of Makati (Local School Board)
Cell Division is one of the most remarkable cellular processes in organisms. All
organisms, from small or big undergo cell division. How and why do cells divide? This
module was designed for Grade 8 students like you. The different activities in this
module will help you understand the processes and importance of cell division. The
module is divided into two lessons, namely:
Lesson 1 – Cell Cycle
Lesson 2 – Meiosis
After going through this module, you are expected to:
1. Describe the stages of the cell cycle;
2. Describe the changes that occur during each stage of mitosis and
meiosis; and
3. Compare mitosis and meiosis.
What I Know
Lesson
1
CELL CYCLE
flow of genetic information from generation to the next through cell division. The
two types of cell division that occur in the body are mitosis and meiosis.
What’s In
Directions. Read each cell riddle below. Analyze which cell part the riddle
describes. Choose your answer from the items in the box below and write your
answer in the space provided.
1
Mitochondrion Cell Membrane Ribosome
Nucleus Centrioles
Riddle #2. I serve as the site of protein synthesis. I have special proteins
and nucleic acids. Guess me! .
Riddle #1. I am the “brain” of the cell, and I control all the activities of the
cell. I am the .
Riddle #3. I am the protective layer Riddle #5. I generate most of the
around the cell, but I am not one cell’s supply of ATP, a source of
solid piece, I have tiny openings that chemical energy. Who am I?
allow materials to pass in and out of
the cell. I am the .
Riddle #4. We have paired
organelles that are present in the
cytoplasm only to participate in cell
division. We help anchor the spindle
fibers in their proper places. Guess
us!
What’s New
In your previous year, you learned the different parts of plant and animal cells.
But, not all cellular parts are involved in cell division. One part of it is a
chromosome that carry hereditary information known as DNA.
Activity 1.0 Chromo-Pick!
Direction: Label the parts of a chromosome. Choose your answer from the items
inside the box.
2
What Is It
One of the most important organelles involved in cell division is the nucleus. This is
the control center of the cell. It contains the genetic material organized into
chromosomes, that carry the DNA, or the hereditary materials that can be passed on
from parent to offspring. They are essential in mitosis and meiosis and are replicated
or duplicated into new daughter cells. Chromosomes are composed of five parts
namely: centromere, chromatid, kinetochore, telomerase, and the upper part p arm
and lower part q arm.
Cell Cycle has two stages: Interphase and Mitosis. Interphase stage has three
substages (1) Gap 1 or G1 is the site of first growth after cell division;(2) Synthesis or
S where the DNA is copied or replicated; (3) Gap 2 or G2 it occurs after DNA has been
copied and the cell will continue to grow and produce new proteins. Mitosis has four
stages (PMAT). In Prophase this is the beginning after interphase where chromatin
condenses, and the nucleolus disappears. During Metaphase the chromosomes line
up at the center or the metaphase plate. In Anaphase the chromosomes break at
centromeres and sister chromatids move to opposite ends of the cell. In Telophase the
cells form two nuclei and finally, the cells begin to split into two.
After Mitosis, there is a formation of two genetically identical daughter cells, each
with the same chromosome number of each parent, and results in the formation of
somatic/body cells.
Plant and animal cells both undergo mitotic cell divisions. They differ in the formation
of daughter cells during cytokinesis. Animal cells form a cleavage furrow that gives
way to the formation of daughter cells. Plant cells don’t form furrows due to rigid cell
wall instead they have cell plate formation.
Schematic diagram of
cytokinesis in plant and
animal cells illustrated by
Alora Rios.
What’s More
B C
A
3
D E
https://en.wikipedia.org/wiki/File:Mitotic_Metaphase.svg
https://commons.wikimedia.org/wiki/File:Mitotic_Prophase.svg
https://commons.wikimedia.org/wiki/File:Mitotic_Anaphase.svg
https://commons.wikimedia.org/wiki/File:Mitotic_Telophase.svg
https://commons.wikimedia.org/wiki/File:Cytokinesis.png
Answer:
Activity 1.3 Let’s Match It!
Direction: Describe the events that occur during the following phases of mitosis.
Write the letter that corresponds to the best answer.
1. Prophase A. chromosomes are aligned at the equator
2. Telophase B. nuclear membrane has totally disappeared
3. Anaphase C. cytoplasm divides
4. Metaphase D. uncoiling of the chromosomes and nuclear
6. Cytokinesis membranes are formed
E. chromosomes separated and moved
toward the poles
Direction: Complete the table by checking the correct column for each statement.
Statement Interphase Mitosis
1.Mitochondria and other
organelles are made.
2.Nuclear division
occurs.
3.Chromosomes are
duplicated.
4.Protein production is
high.
5.Chromosomes are
distributed equally to
daughter cells.
4
What I Can Do
Lesson
MEIOSIS
2
What’s In
In lesson 1, you studied about how a cell goes through a series of events as it grows
and divides to form new cells. Before you start with the next lesson, briefly answer the
questions below.
1. How do the two main stages of the cell cycle differ?
2. Describe the three substages of interphase.
3. What are the main events in each stage of mitosis?
What’s New
Activity 2.0 Mess Me Up!
Direction: Arrange the jumbled letters to form a term used in the study of meiosis.
Write the correct term on the blank.
1.ploiddi - 4. revo singrosc - 7. maaschi -
2.sysisnap - 5. noitcudorper lauxes - 8. Tradet -
3. diolpah - 6. mosomeorch mogousloho- 9. megates -
What is It
Meiosis is a process of cell division which occurs from the sexually reproducing
individuals wherein it reduces the chromosome number from (diploid) into half
(haploid), to compensate for the doubling of the chromosomes during fertilization.
Meiosis stage consists of two successive nuclear cell divisions with only one round of
DNA replication (Meiosis I and Meiosis II).Meiosis 1 is the first division-reduction
division that has four stages: Prophase 1 ,where a homologous chromosomes come
together to form a tetrad and undergo a process of synapsis; Metaphase 1, the paired
homologous chromosomes align at the equatorial plate; Anaphase 1,each member of
the homologous pair separates from the other and moves toward the opposite poles;
Telophase 1, two daughter cells are formed, each has a haploid set of chromosomes,
the result of Telophase 1 is a requirement for Meiosis II. The stages of Meiosis II
known as the second division-gamete formation are as follow: Prophase II, no DNA
replication in this stage, sister chromatids are still attached at the centromere;
Metaphase II, each chromosome align at the equatorial plate; Anaphase II, sister
chromatids of each chromosome separated and moves toward the opposite pole;
Telophase II, four haploid cells are formed. Cell division is complete.
5
After meiosis, four daughter cells are formed from one parent cell. These formed cells
are called gametes or sex cells. The process results to the reduction of chromosome
number in each daughter cell from diploid to haploid. The reduction – division allows
the formation of haploid gametes to ensure that after fertilization, the chromosome
number of the zygote will remain the same as the diploid chromosome number of the
parents.
https://commons.wikimedia.org/wiki/File:Meiosis_Stages_-_Numerical_Version.svg
What’s More
Activity 2.3 Come…Pair Me!! Compare Mitosis and Meiosis by completing the
given table with the needed information.
6
Number of division
Number of daughter cells
produced
Chromosome number of
each daughter
Are the daughter cells
identical?
Purpose/ Importance
● Meiosis is responsible for the genetic variations and physical difference between and
among members of a given species.
● Meiosis is a type of cell division that occurs in the sex cells which reduces the
chromosome number of one sex cell to haploid (23).
● Meiosis involves two nuclear divisions, Meiosis I and Meiosis II. It has 8 stages namely:
Prophase I, Metaphase I, Anaphase I, Telophase I, Prophase II, Metaphase II, Anaphase
II and Telophase II.
● The significance of meiosis is to ensure that all organisms produced through sexual
reproduction contain the correct number of chromosomes. It is of great importance,
because it creates genetic diversity in the population.
● Mitosis occurs in body or somatic cells and produces two identical daughter cells while
Meiosis occurs in germ cells or gametes that produces four haploid daughter cells.
What I Can Do
Directions: Answer the question briefly. Explain the negative effects to humans when meiosis
goes wrong.
Assessment
Multiple Choice. Choose the letter that corresponds to the best answer.
1. What stage of cell cycle is involved in the replication of the DNA?
A. Anaphase B. Gap 1 C. Gap 2 D. Synthesis
2. Why do cells go through mitosis?
A. to synthesize DNA C. to produce energy for the cells
B. to replace damaged cells D. to duplicate their chromosomes
3. Which is the correct sequence of events that occur in Mitosis?
I. Cytokinesis
II. Chromosome condenses.
III. Formation of two nuclei.
IV. Chromosome aligns at the equator plate.
V. Chromosomes moved away going toward the opposite poles.
A. I, II, III, IV and V C. II, III, IV, V, and I
B. II, IV, V, III, and I D. I, III, II, V, and IV
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4. When something goes wrong during meiosis, abnormal conditions happen. In
humans, Down’s syndrome is an example of such abnormality. Why the cells of a
person with Down’s syndrome have an extra chromosome?
A. due to crossing over C. due to nonseparation of body chromosome no.13
B. due to gene segregation D. due to nonseparation of body chromosome no. 21
5. What event normally occurs in meiosis but not in mitosis?
A. chromosome replication C. synapsis of homologous chromosome
B. nuclear membrane disintegration D. movement of chromosomes to opposite poles
References
Baguio, Sol Saranay et.al. 2018 Breaking Through Science 8. (2nd Edition)
C&E Publishing, Inc:
Evangelista, Eden et.al. 2014 Science in Today’s World 8. SIBS Publishing Inc.
Quezon City: 291-300
Rabago, Lilia et.al. 2010 Functional Biology Modular Approach. Vibal Publishing
House, Inc:228-235
Science Learner’s Module 8,2013. Department of Education:317-327
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8
Science
Quarter 4 – Module 3
Gametogenesis
Science – Grade 8
Alternative Delivery Mode
Quarter 4 –Module 3: Gametogenesis
Second Edition, 2021
Republic Act 8293, section 176 states that: No copyright shall subsist in any work of the
Government of the Philippines. However, prior approval of the government agency or office
wherein the work is created shall be necessary for exploitation of such work for profit. Such
agency or office may, among other things, impose as a condition the payment of royalties
Borrowed materials (i.e., songs, stories, poems, pictures, photos, brand names,
trademarks, etc.) included in this module are owned by their respective copyright holders. Every
effort has been exerted to locate and seek permission to use these materials from their
respective copyright owners. The publisher and authors do not represent nor claim ownership
over them.
Hernan L. Apurada
Education Program Supervisor, Science
Printed in the Philippines by the Schools Division Office of Makati City through the
support of the City Government of Makati (Local School Board)
Gametogenesis comes from the Greek word gamos which literally means ‘union’.
In embryology, it is the process of the production of the egg cell and the sperm cell of an
organism. These cells are necessary for the perpetuation of life. In this module, you will
explore varied activities for you to gain a deeper understanding of the process of
gametogenesis in humans.
After going through this module, you are expected to:
1. differentiate between spermatogenesis and oogenesis; and
2. explain how chromosome number is retained in a species.
What I Know
A. A gamete is produced.
B. Gametogenesis has begun.
C. The final phase of spermatogenesis starts.
D. A single sperm and ovum fuse their genetic material to produce an offspring
with the identical number of chromosomes.
Lesso
n Gametogenesis
1
Meiosis is the main event involved in the process of gametes or sex cells formation
known as gametogenesis. Gametes formation can be either: spermatogenesis, which
produces sperms and oogenesis which yields egg or ovum. Both processes undergo
meiosis resulting to the production of haploid daughter cells.
1
What’s In
https://commons.wikimedia.org/wiki/File:Meiosis_Stages.svg
What’s New
The word gametogenesis is a combination of two Greek words which literally means
‘marriage’ and ‘beginning’. It is simply a process of the production of the egg called
oogenesis and sperm cell known as spermatogenesis. For the gametes to serve its
purpose and for fertilization to occur, the sperm cell must search far and wide within
the female reproductive organ for the egg cell. The union of the egg and the sperm
happens in the fallopian tube. A normal healthy male may release 2 million to 1 billion
sperms cells, but only or two sperm cells may complete the fertilization process.
2
Activity 2: Catch me: Search the following group of terms from the word puzzle
below. Then, write a definition for each word on the blank.
1. fertilization
2. oocytes
3. spermatocytes
4. gametes
5. oogenesis
6. spermatogenesis
7. gametogenesis
8. ovulation
What is It
In the first part of the lesson, it is discussed how cells are exactly divided to produce
daughter cells with the same amount chromosome from its parent. While the second
part of this module introduced important terms about gametogenesis. On this part of
the module, we will discuss in detail how the sperm and the egg cell are produced.
Spermatogenesis is the process by which male gametes grow from germ cells in the
testes. In other words, it's how sperms are made. This development involves several
steps of cell division and differentiation. Please note that from the diagram below after
meiosis I, the 46 chromosomes of the spermatocyte produced two haploid cells and
produces four sperm cells after meiosis II. The whole process takes about 74 days.
https://commons.wikimedia.org/wiki/File:Figure_28_01_04.jpg
3
In spermatogenesis, diploid spermatogonia undergo mitosis until they start to develop
into gametes, afterwards, one develops into a primary spermatocyte that will go through
the first meiotic division to produce two haploid secondary spermatocytes. Then, the
secondary spermatocytes will undergo the second meiotic division to each form two
spermatids. Finally, the spermatids will develop flagella and become mature sperm cells.
On the other hand, oogenesis happens in the ovaries of the females. In this process,
diploid oogonium undergo mitosis until one develops into a primary oocyte, which will
start the first meiotic division, but then arrest. It will complete this division as it develops
in the follicle, producing a haploid secondary oocyte and a smaller polar body. The
secondary oocyte goes through the second meiotic division and then arrest again. It will
not complete the second meiotic division unless it is fertilized by a sperm. If fertilization
takes place, a mature ovum and three second polar bodies are formed. The polar bodies
will degenerate. While the ovum is ready to fuse with a sperm cell. Hence, only one egg
cell will mature once a month inside the ovary in a process referred as ovulation.
https://commons.wikimedia.org/wiki/File:Oogenesis_-_Meiosis.png
The haploid sperm cell and egg cell unite during fertilization to form a diploid zygote.
Thus, the normal number of chromosomes is maintained. Since the zygote has both
chromosomes from the mother and the father, the offspring will manifest variation of
traits.
https://commons.wikimedia.org/wiki/File:The_sperm_and_ovum_during_fertilization.svg
4
What’s More
II. Direction: Arrange into proper order the steps in oogenesis by putting numbers 1-6
on the space provided to indicate the correct steps in the process.
Oogenesis
A. Secondary oocyte goes through meiosis II which stops at the metaphase stage
and forms ootid.
B. The primary oocyte goes through meiosis I which stops until the female
reaches puberty.
C. Oogonium develops from the primordial germ cells overlying the ovary.
D. During fertilization, the ootid produces the non-motile, large, and spherical
ovum and the second polar body that degenerates.
E. Oogonium goes through mitosis and differentiates into primary oocyte.
F. When puberty occurs, the primary oocyte forms into haploid secondary oocyte
and one polar body.
III. Comparison Activity
Direction: Supply the necessary information to complete the table below.
Differences between Spermatogenesis and Oogenesis
Properties Spermatogenesis Oogenesis
2. location
3. duration
4. cell division
5. growth phase
6.production rate
7. motility of gametes
5
What I Have Learned
What I Can Do
6
Assessment
4. Oogenesis is the process in the ovary that results in the production of female gametes.
Which is NOT true about oogenesis in humans?
A. Oogenesis begins before birth.
B. Oogenesis continues throughout the life of the individual.
C. At birth, an ovary already contains all the cells it will ever have that will develop into
eggs.
D. In oogenesis, unequal cytokinesis results in one single large daughter cell which goes
on to form the egg.
5. Which are haploid cells?
C. primary spermatocytes and primary oocytes
A. primordial germ cells
B. spermatogonia and oogonia D. secondary spermatocytes and secondary oocytes
7
References
Allas, Ian Mark F. et. al. 2013 Discover Science 8. Philippines : Diwa Learning
Systems, Inc: 117-119.
Aquino, Marites D. et. Al. 2013. Science Links 8. Philippines: Rex Book Store. 131-
135.
8
8
Science
Quarter 4 – Module 4
Mendelian Genetics
Science – Grade 8
Alternative Delivery Mode
Quarter 4 – Module 4: Mendelian Genetics
Second Edition, 2021
Republic Act 8293, section 176 states that: No copyright shall subsist in any work of the
Government of the Philippines. However, prior approval of the government agency or office
wherein the work is created shall be necessary for exploitation of such work for profit. Such
agency or office may, among other things, impose as a condition the payment of royalties.
Borrowed materials (i.e., songs, stories, poems, pictures, photos, brand names, trademarks, etc.)
included in this module are owned by their respective copyright holders. Every effort has been
exerted to locate and seek permission to use these materials from their respective copyright
owners. The publisher and authors do not represent nor claim ownership over them.
Hernan L. Apurada
Education Program Supervisor, Science
Printed in the Philippines by the Schools Division Office of Makati City through the
support of the City Government of Makati (Local School Board)
The journey to unravel the mysteries within us has involved the invention of many
new technologies. This module will help us understand how variation happens and how
traits are being passed from the parent to the offspring. Come and let us discover the
wonderful world of Genetics.
After going through this module, you are expected to:
1. describe the Mendelian principles of inheritance by analyzing Mendel’s
experiment on garden peas;
2. identify the genotypic and phenotypic ratios of offspring in the standard
monohybrid; and
3. solve problems involving Mendelian Genetics.
What I Know
1
Lesso
n Mendelian Genetics
1
Have you ever wondered why you look like your family members? Same
as your puppy or kittens looks like their parents. Even a mango tree in your
backyard tends to bear a mango fruit. In this lesson, you will understand the
idea of Gregor Mendel on how genes can be passed from one generation to the
next.
What’s In
Example:
Shape of hairline
(Widow’s peak,
straight)
Handedness
(right-handed, left-
handed)
Presence of Dimples
(present, absent)
2
1. Based on the accomplished table, do you have more similar traits with your mother
or your father?
2. Are there some traits that you have in which your parents do not have? Cite examples.
3. What explanation you can think of why you differ from your parents in terms of the
trait that you have?
What’s New
What is It
The words used in the previous activity will help you as you learn the concept of
Genetics. Analyze the table below as the important terms are represented.
3
Genetics is the study of the process of inheritance. This field manages to describe how
traits are passed on from one generation to the next. Gregor Johann Mendel, an
Austrian Monk was considered the “Father of Genetics” as he conducted and
performed the first genetics experiment with the use of pea plants in the late 1850s. In
studying Genetics, Mendel chose to closely examine the pea plant for some reason. First,
they have easily recognizable traits. Aside from that, they grow immediately. And lastly,
they can self-pollinate or cross-pollinated. Upon analyzing the pea plant, he discovered
that three out of four plants have one version of the trait and one out of every four would
have the other version. His discovery was true to all seven traits of the pea plants.
Mendelian Principles
2. Law of Segregation
- This law states that the two copies of a gene segregate or separate from each
other during transmission from parent to offspring. Therefore, there can only
be one copy of each gene found in a gamete (sex cells). At fertilization, the two
gametes combine randomly, potentially producing different combinations.
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Monohybrid Cross
A monohybrid cross is the hybrid of two individuals with homozygous genotypes
which result in the opposite phenotype for a certain genetic trait.
The cross between two monohybrid traits (TT and tt) is called a Monohybrid
Cross. The Monohybrid cross is responsible for the inheritance of one gene. It can
be easily shown through Punnett Square. It is also used by geneticists to
observe how homozygous offspring express heterozygous genotypes inherited
from their parents.
Dihybrid Cross
A dihybrid cross explains a mating experiment between two organisms that are
identically hybrid for two traits. A hybrid organism is heterozygous, which means that
it carries two different alleles at a particular genetic position or locus. Therefore, a
dihybrid organism is heterozygous at two different genetic loci.
Example: A pea plant that is heterozygous for round, yellow seeds is self-fertilized, what
are the phenotypic ratios of the resulting offspring?
1. Determine the parental genotypes. P generation: RrYy x RrYy
2. Determine the gametes. Gametes: RY, Ry, rY, ry (parent 1) and RY, Ry, rY, ry (parent 2).
3. Set up a large 4x4 Punnett square, place one gamete set from the parent on the top, and
the other on the side.
4. Write the genotypes of the offspring in each box and determine how many of each
phenotype you have.
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RY Ry rY ry Genotype: RRYY= 1; RRYy= 2; RrYY= 2; RrYY= 2;
RrYy= 2; Rryy= 2; rrYy= 2; RRyy= 1; rrYY= 1; rryy=1
RY RRYY RRYy RrYY RrYy
Genotypic ratio: 1:2:2:2:2:2:2:1:1:1
Ry RRYy RRyy RrYy Rryy
Phenotype: Round, yellow= 9; Round Green= 3;
rY RrYY RrYy rrYY rrYy Wrinkled yellow= 3; wrinkled green= 1
ry RrYy Rryy rrYy rryy Phenotypic ratio: 9:3:3:1
What’s More
1. gg 2. Jj 3. KK 4. Ll 5. Mm 6. ZZ
gg Gg GG
2. A Widow’s peak hairline (H) is dominant to a straight line (h). Cross a heterozygous
Widow’s peak hairline to a straight hairline person.
What is the genotype of the parent?
Result - Genotype: Genotypic ratio:
Phenotype: Phenotypic ratio:
3. Cross two light-haired people if brown hair is dominant over light-colored hair—use
D and d as your alleles. What is the genotype of the parent?
Result - Genotype: Genotypic ratio:
Phenotype: Phenotypic ratio:
4. The following letters represent the genotypes of rabbits. GG= gray hair, Gg= gray hair,
gg= white hair, BB= black eyes, Bb= black eyes and bb= red eyes. A male rabbit with
the genotype GGbb is crossed with a female rabbit with the genotype ggBb the Punnett
square is set up below. Fill out and determine the phenotypes and proportions in the
offspring.
a. How many out of 16 have gray fur and black eyes?
b. How many out of 16 have gray fur and red eyes?
c. How many out of 16 have white fur and black eyes?
d. How many out of 16 have white fur and red eyes?
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5. Given the following information: dominant allele for black fur= B, recessive allele for
white fur= b, dominant allele for rough fur= R, recessive allele for smooth fur= r. Cross
a heterozygous parent (BbRr) with a heterozygous parent (BbRr) guinea pig.
a. What is the probability of producing guinea pigs with
black rough fur? Possible genotypes:
b. What is the probability of producing guinea pigs with
black, smooth fur? Possible genotypes:
c. What is the probability of producing guinea pigs with
white, rough fur? Possible genotypes:
d. What is the probability of producing guinea pigs with
white, smooth fur? Possible genotypes:
Genetics is the study of the process of inheritance and Gregor Johann Mendel is
the father of Genetics.
Mendelian principles include Law of Complete Dominance, Law of Segregation,
and Law of Independent Assortment.
A monohybrid cross is the study of the inheritance of one characteristic.
A dihybrid cross explains a mating experiment between two organisms that are
identically hybrid for two traits. It also carries two different alleles at a particular
genetic position or locus.
Punnett Square is used by geneticists to observe how offspring express genotypes
inherited from their parents.
What I Can Do
Word Choice The poem uses many The poem uses The poem uses The poem uses
precise, vivid, and several descriptive general or ordinary general or ordinary
and Main descriptive words to words to develop a terms to develop a terms to describe
Idea develop a central idea central idea or central idea or the objects; the
or message about message about message about words do not
Mendelian Genetics. Mendelian Genetics Mendelian Genetics. develop a central
idea or knowledge.
Spelling There are no or very There are spelling Numerous spelling Numerous spelling
few spelling errors. errors, which may or errors impede the errors impede the
They are may not be reader from reader from
developmentally developmentally understanding the understanding the
appropriate and do appropriate. However, poem’s message. poem’s message.
not impede the they do not impede Some of the mistakes Unfortunately,
reader's the reader's are developmentally mistakes are not
understanding of the understanding of the appropriate, but developmentally
poem. poem. others should have and should have
been noticed and been noticed and
corrected. corrected.
Creativity Very creative ideas Has many creative Has some creative Shows little or no
and illustrations. ideas and illustrations ideas and creativity.
illustrations
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Assessment
5. Normal kernels are dominant to waxy kernels. What type of seed will be produced
if you crossed a waxy kernel plant to heterozygous normal plant?
A. All are normal kernel.
B. 1 normal kernel: 1 waxy kernel
C. 1 normal kernel: 3 waxy kernel
D. 2 normal kernel: 2 waxy kernel
References
Brooker, Robert J. 2016. "Mendelian Inheritance." In Concepts of Genetics Second
Edition, by Robert J. Brooker, 42-55. New York: McGraw-Hill Education.