Computed Tomography Scan - Lecture Notes - 2023 - Ver. 1
Computed Tomography Scan - Lecture Notes - 2023 - Ver. 1
Attenuation is generally described as the reduction of X-ray Intensity through the process of
Scattering and Absorption as it passes through matter.
➢ Applying this concept in Radiology, the difference in atomic composition (Atomic
Number and Mass) is a major factor for the attenuation of the X-ray Beam – since
the human body is a complex and diverse system the possibility of scattering and
absorption varies.
➢ The variations in the human body accounts for the process known as differential
absorption. Which suggests that different Z number would dictate the differences in
the X-ray attenuation (whether it may or maybe scattering or absorption).
➢ Linear Attenuation Coefficient which the unit of measure for the amount X-ray
intensity is absorbed as it passes through matter.
▪ It is commonly denoted by the Greek Letter (μ) with a unit of 𝒄𝒎−𝟏
▪ This unit is used as another method of measuring Beam Quality
second best to Half Value Layer (HVL).
Hounsfield Units (HU) otherwise known as the “CT numbers”, it is a unit of numerical
measurement that account to the radiodensity of the material based from its Linear
Attenuation Coefficient or simply the ability of the material or tissue to absorb X-ray photons.
➢ That is why the CT numbers are classified into:
o Hyperdense – White Color
o Isodense – Gray Color
o Hypodense – Black Color
➢ REMEMBER that the basis for the Hounsfield Units is from the X-ray absorbing
power of water (Linear Attenuation Coefficient).
The Hounsfield Units are the numerical measurement of Radiodensity based from the Remnant
Radiation (otherwise known as Exit Radiation) are the X-ray photons that were transmitted
from the body and then intercepted by the RADIATION DETECTORS.
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➢ 1st Generation which is known in the following names: MARK 1; Brain Tissue
Scanner; EMI Scanner.
o TRANSLATE/ROTATION
o Inventor/s: Godfrey Hounsfield & Allan Cormack
▪ It was 1st installed at ATKINSON MORLEY HOSPITAL in the United
Kingdom.
▪ Take Note: 180 translations are needed for the completion of an
image sequence.
o X-ray Tube: Pencil Beam
o X-ray Detector: 1-3 x-ray detectors are used and arranged in a Linear
Fashion.
o Scan Time: 3-5 minutes per translation.
o Its application is only limited to Neurologic Imaging.
▪ This generation has a standard 80x80 matrix size.
➢ 2 Generation which is known to be the ACTAS (Automated Computerized
nd
o ROTATE-ROTATE
o X-ray tube: Wide Fan Beam which is mainly controls the beam divergence to
conform with the curvilinear array of detector configuration.
o X-ray Detectors – uses 750 – 1000 detectors that is arranged in a Curvilinear
Fashion to conform with the curvature of the beam divergence and human
anatomy.
▪ This diminished the region of penumbra from the 2nd Generation.
▪ The control of Scattered Radiation is through the use of Thin
Tungsten Septa.
o Scan Time: 0.35 seconds – 10 seconds per slice.
o Disadvantage: This generation has one main draw back – a misalignment of
the x-ray detectors can cause the development of RING ARTIFACT which is
formed in the center of the image.
➢ 4th Generation
o ROTATE-STATIONARY
o X-ray Tube: Wide Fan Beam
o X-ray Detectors: This generation of CT scanners used a Stationary X-ray
Detector Ring which solves the problem of the 3rd Generation CT Scanner
for the existence of Ring Artifacts.
▪ The use of Thin Tungsten Septa is still in place to reject the Scattered
Radiation.
o Scan Time: less than 1 second per slice.
o Disadvantage: The Radiation Dose has dramatically increased due to the
short SID of the X-ray Tube to the Patient.
➢ 5 Generation aka. Electron Beam CT scanner (EBCT) and Heart Scanner
th
o STATIONARY-STATIONARY
o Inventor: Andrew Castagnini
o X-ray Tube: Electron Gun Beam
▪ This X-ray tube uses an energy that operates at a max of 130
kilovoltage.
▪ The Electron Beam will energize the Stationary Tungsten Rings that
will generate the X-ray Photons during exposure – the stationary
tungsten rings are composed of 4 Tungsten Rings.
o X-ray Detectors: this generation of CT scanners uses a Stationary Detector
Rings – mainly comprising of 4 X-ray detector rings.
▪ Advantage: among all of the CT scanner Generation, the EBCT has the
BEST TEMPORAL RESOLUTION.
o Scan Time: 50-100ms
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System Components:
The Computed Tomography scanners have 4 main components:
1. CT Gantry
2. Patient Table
3. Computer
4. Control Console
CT Gantry is the largest component of the CT scanner which has an opening that is called as the
Aperture; the aperture has a circular opening that is measured to be 28 (71.2 cm) inches in
total diameter.
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➢ The gantry has a capability to tilt/ change direction according to the selection of the
Radiologic Technologist – it is said that the Gantry can be tilted from 15 – 30
degrees.
a. Laser Localizers – these are lasers that are used for localizing body landmarks during
the scanning of the patient.
b. Isocenter is the middle/ central region inside the aperture; it a place where dose is
equal in all directions.
o If in case the patient is not placed in the Isocenter: there would be image cut off,
unequal distribution of radiation, formation of noise.
c. X-ray Tube of CT Scanners have higher specifications in comparison with the X-ray tubes
that are normally seen in Conventional Radiography.
o The X-ray tube uses a target material - Rhenium Tungsten to increase the
efficiency and boiling point of the tungsten which have a boiling point of 3410
degree Celsius. Having the Anode construction to be a Rotating Anode that is
effective in Heat Dissipation.
o The Filament also uses an alloy of Thoriated Tungsten to enhance the efficiency
of Thermionic Emission.
Computed Tomography X-ray Tube Conventional Radiography X-ray Tube
Straton is the X-ray tube that is dedicated Coolidge is the X-ray tube that is
for CT Scanners. dedicated to Conventional X-ray Machine.
DISADVANTAGE: it has Poor Detector Efficiency Rate (60-80%) which is caused by the
construction of the Front Window that acts an attenuating barrier with the incoming
X-ray photons and Aluminum Casing that keeps the pressurized Xenon Gas, further
attenuate the X-ray photons before it even causes an Ionization event with the
pressurized gas inside.
2. Scintillation Detectors (aka. Solid State Detectors) uses Photoreactive crystals to
generate light signals through an indirect process of conversion through Excitation of
photoreactive crystals.
➢ The Excitation even will directly produce light signals that is equivalent to the
intensity of the ionizing radiation. These light signals will be collected by the
Photodiode for it to be converted into Electronic Signals.
The following are the list of Photoreactive Crystals:
➢ Bismuth Germanate Oxide (BGO) – mostly used detector for PET Scanners.
➢ Cadmium Tungstate (CdWO4) – “Most Preferred” Photoreactive Crystal used as a
Detector for CT Scanners
➢ Cesium Iodide (CsI) – mostly used as a material for Image Intensifier in Fluoroscopy.
➢ Sodium Iodide (NaI) – obsolete photoreactive crystal in CT; but widely used in Gamma
Cameras in Nuclear Medicine.
ADVANTANGE: it is widely chosen over a Gas Filled Detector due to it 100% Absorption
Rate.
DISADVANTAGE: it is susceptible to afterglow due to low response time; this is
alongside the hygroscopic property of photoreactive crystals which they have high
affinity to water and moisture.
o This is why there CT Scanners have dehumidifier inside the CT scan room.
X-ray Photon events – remember when X-ray events are overlapping this leads to
Afterglow event).
Patient Couch/ Table function is to carry the patient during the scanning process, places the
patient in the Isocenter of the Aperture.
o The material used in the Patient Table should be low atomic number; low
attenuating material such as Wood and Carbon Fiber which can carry a weight
limit of at least 220lbs.
The Table Movement in CT terms are called as Table Increments/ Indexing which is
used for the older generations of CT Scanners (from 1st to 5th Generation). While the
Table Pitch is an exclusive term that should be used for the newer generations of CT
Scanners (6th and 7th Generation).
NOTE: the Table Indexing/ Pitch is one of the Primary Controller of Slice Thickness.
**Scannable Range is the degree the patient table can move horizontally.
**Table Pitch is also defined as ratio of table speed/feed to slice thickness. This can be
expressed using the equation below:
𝑻𝒂𝒃𝒍𝒆 𝑰𝒏𝒅𝒆𝒙𝒊𝒏𝒈
Table Pitch =
𝑺𝒍𝒊𝒄𝒆 𝑻𝒉𝒊𝒄𝒌𝒏𝒆𝒔𝒔
Table Pitch is given in ratio values, it can be interpreted as table movement (number of increments)
indicating distance of slice thickness per gantry rotation.
Example: if the Ratio value given is 2:1, this simply means that table has moved twice (2x) in a single
gantry rotation.
➢ Table Pitch value indicates the speed of indexing/ table feed.
o If the Pitch is > 1 (greater) – the speed of indexing is fast.
▪ This is prone to image blurring
▪ A fast table speed is very useful in covering a large amount of Anatomy
when scanning hence favorable for CT contrast and angiography studies.
o If the Pitch is <1 (less than) – the speed of indexing is slow.
▪ This yields for high spatial resolution but in the cost of high patient
radiation dose.
NOTE: the most ideal value of table pitch should always be equal to 1 – 1.5.
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Computer serves as the link between the Radiologic Technologist and CT components.
➢ The computer in aiding data acquisition, image reconstruction, display and post
processing.
Storage – the modern storage of all digital is through the Picture Archiving and
Communication System.
- it uses a file extension known as .dicom (Digital Communications in Medicine) other file
extension is .hl7 (Health Level 7).
Control Console is a CT component where the Radiologic Technologist can control and monitor
scan parameters.
Uses a single row of X-ray Detectors to Uses multiple rows of X-ray Detectors to
acquire images. acquire images – also known as Flat Panel
Detectors.
This is exclusive to the older generations of
CT Scanners – 3rd and 4th Generation. This is exclusive to 7th Generation CT
Scanners who are capable of producing 16,
The Slice Thickness is controlled by the 32, 64 or even higher number of CT slice in a
Collimator Assembly. single Gantry Rotation.
Other type of CT Scanner is the Dual Source CT Scanner (DSCT) this type of CT scanners utilizes
two X-ray Tubes with a Single Row of X-ray Detector Element.
- This is exclusive to 6th Generation of CT Scanner; which is advantageous – the dual
source X-ray tube will provide a higher detail due to the dual energy source.
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X-ray Tube
Pre-Detector Collimator
CT Image Data
Remnant Radiation
(Measurement Data)
X R D T R
DAS Pre-Processing:
(Analog-to-Digital Conversion) (Raw Data)
Reconstruction
Computer Fourier Convolution Filtered CT Data Algorithm
Transform
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Image Reconstruction
The Ray, Ray Sum, View, Attenuation Profiles (aka. Scan Profiles, Projection Profiles)
1. Ray/s are the pathway of the X-ray Photon from the X-ray Tube towards the detector.
2. Ray Sum is the detection of the individual rays and measurement of X-ray beam
attenuation.
3. View is the complete set/ grouping of Ray Sum.
4. Attenuation Profile – is the way the CT system profiles/classifies the characteristics of
each ray sum and the correlate its position to the position of the ray.
Rays
Finished Image
Ray Sum
and View
Attenuation Profiles
There are four types of CT Data that is processed during image reconstruction:
Reconstruction Algorithms
1. Back Projection (aka. Summation Method)
Is a computer algorithm that is used to reconstruct CT images through the combination
(summation) of scan profiles from the patients in a 360-degree perspective as the X-ray Tube
completes a single rotation per table increment.
Disadvantage: formation of the Star Pattern Artifact.
2. Filtered Back Projection (aka. Summation Method)
Is an improvement of the Back Projection Method which has the capability to eliminate
the Star Patter Artifact through the use of Fourier Transformation and Convolution Filters.
➢ Fourier Transformation – is a mathematical technique that was developed by Jean-
Baptiste-Joseph Fourier. It is widely used in Digital Signal Processing (DSP), the
collected signals are transformed through the decomposition (separation) of bundled
signals into its individual components; it can also be used to map/locate each
individual signal for image processing and reconstruction.
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A. Discrete Fourier Transform (DFT) is used for finite range of signals that is used to
digitize frequency signals.
B. Fast Fourier Transform (FFT) is a variation of Fourier Transform which can cover
a wide range of frequency signals and digitize all of these analog signals faster
than DFT.
➢ FFT’s are also used in Ultrasonography particularly in Doppler Mode.
Application of FT is very evident with the Convolution of Frequency Signals when using a
Filtered Back Projection algorithm which uses a filter to create an image that is pleasing/ in line
with the clinical question for the improvement of either Contrast/ Spatial Resolution.
➢ Convolution Filters (aka. Kernels) is a computer algorithm that is used to suppress
“filter” individual digital signals such as High/ Low Frequency signals to improve the
image quality of the CT image.
The resultant CT image has a High Contrast The resultant CT image has a High Spatial
Resolution – this process of increasing Resolution which is very ideal for Small
Contrast Resolution is known to be Structure Imaging.
“Smoothing” which is very ideal for Organ
Imaging. Characterized by High Noise and Low
Contrast Resolution.
Characterized by Low Noise Image and Low
Spatial Resolution.
o An increase in the
Number of Iterations;
Improved image
quality; increased
reconstruction time.
4. Maximum Intensity Projections (MIP) is an image rendering technique which uses voxel
and pixel that contains High Intensity Projection data to form 2-dimensional images - a
good image rendering technique when evaluating bones and contrast filled structures
(Angiography Studies).
2. Voxel (aka. Volume Element) is the tissue volume of the CT image. It is directly affected
by the slice thickness.
An Isotropic Voxel is the ideal type of
voxel which is shaped as a Cube. This
indicates that are loss of CT data due to
the volume averaging by increasing slice
thickness.
A Voxel’s volume can be calculated
through the use of this equation below:
𝑽𝒐𝒙𝒆𝒍 = (𝑷𝒊𝒙𝒆𝒍 𝑺𝒊𝒛𝒆)(𝑺𝒍𝒊𝒄𝒌 𝑻𝒉𝒊𝒄𝒌𝒏𝒆𝒔𝒔)
Determines the area of the gantry which the Determines the amount of raw data
raw data is acquired. that is going to be used for
reconstructing an image.
Simply the area of the Aperture that is the computer during the post-
scanned – from the Isocenter extending from processing stage:
the distant edge of region of interest.
PIXEL and MATRIX SIZE.
REMEMBER: DFOV cannot be bigger than SFOV – because the SFOV is the basis and control
for acquiring the raw data before it is transformed into an image data. While the DFOV
only controls the finished image data – This means DFOV is dependent on SFOV.
5. Window Setting (aka. Gray Level Mapping) is a post processing technique which adjusts
or maps the different shades of gray.
Contrast Resolution is the ability of the imaging system to resolve/ differentiate between
objects that have the same densities as their background.
High Contrast
Low Contrast
Resolution
Resolution
Image
Image
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Parameters Results in
Increase Noise Decreases Contrast Resolution
(Increasing noise degrades the Contrast
Resolution of the image due to the loss/
fluctuation of pixel values due to
insufficient detected photons).
Increasing Slice Thickness Increases Contrast Resolution
(Increasing Slice Thickness increases the
voxel size which in turn increases the
detected X-ray photons)
Increasing Pixel Size Increases Contrast Resolution
(Increasing Pixel Size will increase the
detected photons).
Increasing Voxel Size Increases Contrast Resolution
(Increasing Slice Thickness increases the
voxel size which in turn increases the
detected X-ray photons)
Increasing Matrix Size Decrease in Contrast Resolution
(Increasing Matrix Size means that the sizes
of pixel are decreasing thus the noise
increases due to the number of rows and
columns that needs to filled with
insufficient number of photons).
Increase mAs Increase in Contrast Resolution
(Increasing mAs will entail increased
number of X-ray photons which fills the
Matrix).
Increasing kvp Decreases Contrast Resolution
(Increasing Kvp will entail a Higher
Scattered Radiation that leads to Noise
Formation and Long Scale of Contrast)
CT imaging Artifacts:
It is caused by Tungsten
Vaporization; Presence of
Gas in the X-ray tube
Envelope.
Appears as Single-Multiple
Streaks in the CT image.
Ring Artifact Occurs when there’s a
misalignment of the X-ray Calibration of X-ray
Scanner Based Artifact Detectors. Detectors by the Service
Engineers.
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CONTRAST MEDIA
➢ Positive Contrast Media – appears as White due to High Attenuation capabilities of
these substances.
o Barium Sulphate
o Iodinated Contrast Media
➢ Negative Contrast Media – appears as Black due to Low Attenuation capabilities of
these substances.
o Air – Carbon Dioxide or Room Air
CONTRAST MEDIA DELIVERY TECHNIQUES & SCAN DELAY METHODS:
➢ There are 2 CM delivery techniques:
o Drip infusion Method uses the force of gravity to deliver the contrast to the
patient with use of elevated IV line.
▪ Take note this technique doesn’t produce a “Peak Contrast”
enhancement because of the slow contrast media introduction rate
into the body.
o Bolus Technique is a method that delivers Contrast Media in a Rapid
Injection Rate which can be achieved by:
▪ Mechanical Injector (Power Injector)
▪ Hand Bolus Injection
➢ There are 2 methods of Scan Delay
o Test Bolus - method of administering CM of 10-20mL via IV line; to
determine the length of time from the injection of CM to Peak
Enhancement in the Organs.
o Bolus Tracking (aka. Automated Triggering; Bolus Triggering) – is a method
using a bolus of Contrast Media to start a Scan; this technique uses low-
radiation dose scans to monitor (known as the Monitor Scans) the progress
of contrast enhancement in the body.
PHASES OF CONTRAST ENHANCEMENT AND CONTRAST EXAMINATION TYPES
➢ Arterial Phase (aka. Bolus Phase) is the first phase of the Contrast Media Flow; no
contrast media is seen at this phase of the CM flow.
o 20 -30 seconds is the theoretical average time for the Arterial Phase.
➢ Venous Phase (aka. Non-Equilibrium Phase) occurs when the Contrast Media has
already been administered through the patient; scanning should be performed at
an average time of 60 post-injection.
o Venous Phase is the second phase of the CM Flow
o It has a Theoretical Average Time of 60-70 seconds.
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➢ Delayed Phase (aka. Equilibrium Phase) is the last phase of the Contrast media
enhancement; it is where the contrast media has already been completely drained
from the organ.
PATIENT CONSIDERATIONS
The following list should be considered when a patient is required to undergo a CT scan
procedure that entails the administration of IV contrast, Biopsies, and Fluid Drainage:
1. Laboratory Examination:
a. Creatinine and Blood Urea Nitrogen (BUN) – are the laboratory examination
that tests the Renal Function of an individual – particularly for examinations
with IV contrast
b. Prothrombin Time (PT) and Partial Thrombin Time (PTT) – are set of laboratory
examination that tests for blood coagulation ability of an individual –
particularly for CT Guided Biopsies and Fluid Drainage.
2. Patient History – the Radiologic Technologist should be well of the following:
a. History of Asthma – considered as a risk factor for adverse reaction to IV
contrast administration knowing that Asthmatic are 5x more prone in
comparison to healthy individual.
b. History of Allergy with Food, Medications, and other substances – this is one of
the factors that increases the risk of developing adverse reaction with IV
Contrast Media administration.
c. Patients with Diabetes Mellitus (Type II) in Metformin Therapy – this increases
the risk of adverse reaction of IV Contrast with Metformin which may lead to
Lactic Acidosis or in patient who are diagnosed with Diabetes alone with
controlled blood sugar to develop a condition of Contrast Induced Nephropathy
(CIN) due to IV contrast media administration.
▪ Metformin should be WITHELD FOR 2 days; 1 day before the
examination and 1 day after the examination.
3. Use of Pre-medications – is a technique that is used to decrease the incidence of any
allergic reaction with IV Contrast Administration this is done through the combination
of Steroids (Corticosteroids) and (Antihistamines – e.g., Benadryl). The administration
of these drugs is done before the administration of
➢ Kothari Method and 3D volume pixel Method – these are the methods of measuring brain
bleeds in patients suffering from Intracranial Hemorrhage (especially CVA’s) but limited in
measuring brains bleeds that are near to Bone Structures, Axonal Injuries, Cerebellar and
Pontine Bleeds.
Brain Perfusion Studies is a CT imaging protocol that is used to tissue viability of patient who
had suffered a Cerebrovascular Accident (CVA) or most commonly known as “Stroke” –
especially useful identifying areas in the Brain tissue that are considered as:
➢ “Non-salvageable” or “Neuronal death” – which is collectively called as “Core
Infarcts”- these are areas of the brain which have occluded blood supply due to the
presence of embolus or thrombus.
➢ “Ischemic penumbra” – these are areas of the brain which have partial occlusion of
blood supply due to the presence of embolus or thrombus.
Take Note:
Core Infarcts – Decreased in both CBV and CBF with an Increase in MTT.
Ischemic Penumbra – Increased MTT, preserved CBV; decreased CBF.
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To better identify and visualize the relevance of MTT, CBV, and CBF. A color-coded software is
used by modern CT scanners to demonstrate the mismatch of CBF, CBV and MTT mismatch
values.
Patient Position
Prone Supine
Used to differentiate pathologies in Anterior The standard position for CT imaging.
and Posterior areas of the Thorax that could
be missed in a Supine Position Scan due to
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This is used for HRCT for maximizing This is used only when there is a need for
contrast enhancement with the use of comparison (depending on clinical
AIR. This is also to ensure that the lung is question). As Expiratory Scan are useful
at its full capacity. in detecting the areas of the lungs that
does not empty air (air trapping); which
is common for Bronchiectasis and Cystic
Fibrosis.
CHEST CT ANGIOGRAM
A routine Chest CT Angio is a useful tool in diagnosing Pulmonary Embolism in a non-
invasive manner. This is because the traditional route of diagnosis is usually performed with
the use of Pulmonary Angiography procedures.
Other options may include the use of V/Q Scintigraphy.
CARDIAC CT IMAGING
Cardiac CT imaging is definitely one of the difficult organs in the body to obtain CT
images due to the rapid involuntary movements that is caused by Heart Contractions. To be able
to obtain high quality CT images of the Heart the following are used:
Techniques for Cardiac CT Imaging
Pharmacologic Control This uses a pharmacologic agent: Beta-Blockers which has a
mechanism of action to slow down the heart of the patient to
less than 65 – 70 bpm.
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