Nutrition-GSCI1045 Lecture - Week 10
Nutrition-GSCI1045 Lecture - Week 10
Nutrition-GSCI1045 Lecture - Week 10
Week 10
That's a lot, so be sure to go through the modules one part at a time. Maybe separate it into
three sections, taking a break between each one.
o Vitamins that can be dissolved in water are called water soluble vitamins.
o Vitamin C and B-complex are the water soluble vitamins.
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o It is rare to have a toxicity of water soluble vitamins in the body as any excess is
removed through urination.
o Because water soluble vitamins are not stored in the body, RDA values need to be
consumed in the diet daily.
Fat Soluble Vitamins
o Vitamins that are not soluble in water but can be stored in body fat are called fat soluble
vitamins.
o Vitamins A, D, E and K are the fat soluble vitamins.
o The RDA value of fat soluble vitamins doesn't need to be consumed daily but the
average amount should be taken in the diet every other day or so.
o Because fat soluble vitamins are stored in body fat, over consumption can result in
toxicity.
o Conversely, anything that reduces or blocks the absorption of fat into the body may
also lead to a deficiency of fat soluble vitamins.
Vitamin A
o Vitamin A is a fat soluble vitamin stored in the liver.
o It plays a key role in healthy vision and contributes to normal growth and development.
o It also helps keep our immune systems healthy.
Sources
o The most bioavailable and easily absorbed forms of Vitamin A come from animal food
sources.
o Plants contain no active vitamin A, but many vegetables and fruits contain the vitamin
A precursor, beta-carotene.
o Beta-carotene is converted to the active form of vitamin A by the body when plant-
based foods are consumed.
o Health Canada recommends that we eat one dark green and one orange vegetable or
fruit each day to contribute to our daily intake of vitamin A.
Requirements
Age in Years Vitamin A Don't exceed (ug/day)*
needs micrograms (ug)/day*
Men 19 and older 900 3000
Women 19 and older 700 3000
Pregnancy (19 and older) 770 3000
Lactation (19 and older) 1300 3000
Source: EatRight Ontario
Deficiencies:
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Vitamin D
o Vitamin D is a fat soluble vitamin that regulates bone integrity, acts as a hormone and
stimulates maturation of body cells.
o Vitamin D helps our body absorb calcium, helps with healthy teeth, bones, muscles,
and immunity.
o “The sunshine vitamin”, Vitamin D, has had a lot of attention over the last few years,
resulting in an increase in recommended amounts for all age groups.
Requirements
Age group Aim for an intake of Stay below IU/day*
international units (IU)/day
Infants 0-6 months old 400 1000
Infants 7-12 months old 400 1500
Children 1-3 years old 600 2500
Children 4-8 years old 600 3000
Children and Adults 9-70 years 600 4000
old
Adults over 71 years old 800 4000
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Sources
o Vitamin D is produced when ultraviolet rays from the sun strike the skin and trigger its
production. Foods that contain Vitamin D include egg yolks and fatty fish such as
salmon, mackerel, sardines and tuna. Dairy products have added vitamin D as required
by the Canadian government. Other foods that are may be fortified with Vitamin D
include yogurts, cheese, Goat’s milk, soy beverages, and some orange juices.
Deficiencies
o Rickets in children, chronic illnesses and multiple sclerosis.
Toxicity
o Symptoms of toxicity include appetite loss, nausea, vomiting, and increased urination
and thirst.
o Severe form of psychological depression can result from vitamin D’s effects on the
central nervous system.
Vitamin E
Roles
o As an antioxidant, Vitamin E is a fat-soluble vitamin responsible for protecting body
tissue from damage caused by harmful molecules called "free radicals."
o It protects lipids and prevents the oxidation of polyunsaturated fats and helps to
maintain a healthy immune system.
o It also enhances the dilation of blood vessels and inhibits blood clot formation.
Sources
o Vitamin E is in many food but especially those that are higher in fats.
o It is naturally present in vegetable oils, avocados, leafy green vegetables, wheat germ,
sunflower seeds, and some nuts.
Recommended Daily Amounts
Age RDA UL
Vitamin E needs (mg/day) Don't exceed (mg/day)
19 years and older 15 1000
Pregnancy 15 1000
Lactation (breastfeeding) 15 1000
Vitamin K
Role
o Fat soluble Vitamin K assists with blood clotting and synthesis of bone protein. It helps
our body heal wounds, maintains blood vessels and keep our bones healthy.
Sources
o We get most vitamin K from foods, especially greens like broccoli, brussels sprouts,
cabbage, spinach, green onions, and kale.
o It is produced by the bacteria in the small intestine upon eating insoluble fiber in the
greens previously mentioned.
o Vitamin K is best absorbed when consumed with small amounts of oil or fats.
Recommended Daily Amounts
Vitamin K
Age Amount needed per day in micrograms
Vitamin C
Role
o Two roles for the water soluble Vitamin C are making collagen and acting as an anti-
oxidant.
o Vitamin C keeps gums healthy, helps us heal, protects us from bruising, helps with
blood and bones and aids in absorption of iron from plant based foods.
Sources
o Vegetables and fruits are good sources of Vitamin C. For example, red bell pepper, kiwi
fruit, citrus fruit.
Recommended Daily Amounts
o As a water soluble vitamin, Vitamin C is expelled from the body and not stored.
Therefore, we need to eat food rich in Vitamin C every day.
Age Vitamin C mg/day
1-3 years 15
4-8 years 25
9-13 years 45
14-18 years
Males 75
Females 65
Males 19+ 90
Females 19+ 75
Pregnancy <18 years 80
Pregnancy >19 years 85
Lactation <18 years 115
Lactation >19 years 120
Smokers Add 35 mg to your usual daily needs
Source: EatRight Ontario
Deficiency
o A Lack of vitamin C can result in bruising, poor healing of wounds, bleeding gums, loose
teeth and infections.
o Vitamin C deficiency can lead to Scurvy, a disease characterized by swollen bleeding
gums and the opening of previously healed wounds.
o In the 18th century it affected poorly nourished sailors who traveled long distances
without fresh food containing Vitamin C.
Toxicity
o As a water soluble vitamin cases of toxicity are rare because excess Vitamin C is expelled
in urine.
o Large doses of Vitamin C can cause digestive distress and diarrhea and may interfere
with insulin production rate.
o Vitamin C supplements may interfere with some prescription medications.
Bioavailability
o Vitamin C is easily destroyed by heat and oxygen.
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o Fresh, raw, and quickly cooked fruit, vegetables, and juices retain the most vitamin C.
B Vitamins
Role
o The B Vitamins: B1 (thiamine) , B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6
(pyridoxine), B7 (biotin), B9 (folate) and B12 (cobalamin).
o The B Vitamins are a group of eight water soluble vitamins that act as co-enzymes. A
co-enzyme is a non-protein compound necessary for the functioning of an enzyme.
o B Vitamins activate more than a 1000 enzymatic reactions in the human body.
o As co-enzymes, they are involved in the breakdown of nutrients and in the building of
macromolecules, such as protein, RNA, and DNA.
o They play an important role in cell metabolism.
In the image here, coenzymes and cofactors are the particular vitamin or mineral required
for enzymes to catalyze a specific reaction.
Deficiencies
o Vitamin B deficiencies can occur in those with certain diseases.
o Alcoholism is linked to deficiencies in B vitamins.
o B vitamin deficiencies are most often seen in the mouth area.
o The deficiencies of individual B vitamins often occur in unison with other B vitamin
deficiencies.
Vitamin B6
Vitamin B9
Breastfeeding Women 19
500 1000
years and older
*This includes sources of folate from food and supplements Source: Dietitians of Canada
Deficiency
As it helps make red blood cells, a lack of folate can lead to anemia. Other effects include
birth defects (neural tube), diminished immunity, abnormal digestive function,
cardiovascular disease and cancer (colon, cervical) risk increase. Because of its importance
foods are now fortified with folate, cereals are sprayed with it.
Toxicity
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Antioxidants
o An antioxidant is a molecule that can inhibit the damage done by free radicals.
o Antioxidants have the ability to donate an electron to the unstable free radical and at
the same time they remain stable.
Oxidative Stress
o Oxidation occurs when our immune system sends germ attacking cells to tackle an
intruder.
o These immune cells are called microglia, which produce free radicals to attack and kill
the intruding germs.
o These free radicals are necessary, but if left unchecked they can also attach to healthy
cells and kill them.
o Oxidative stress is an imbalance between the production of free radicals and the ability
of the body to detoxify and repair damage to cells.
o When there is insufficient detoxification and repair, the result is oxidative stress.
Antioxidants act as defense against free radicals.
o Free radicals can damage and destroy lipids, proteins, RNA, and DNA, which can
contribute to disease.
Example of Apple dipped in lemon juice
o To get an idea of what oxidation is, think about what happens when you cut an apple
and leave it for a minute. The apple exposed to air oxidizes and turns brown. We can
show how an antioxidant works by considering what happens when we dip our cut apple
into lemon juice. The vitamin C in the lemon juice is an antioxidant; it prevents the apple
from turning brown. In the same way the lemon juice protects the apple, our body uses
antioxidants to protect itself from deterioration from oxidation.
o Oxidative stress has been implicated as a contributing factor in diseases such as
cancer, atherosclerosis (hardening of arteries), arthritis, diabetes, kidney disease,
Alzheimer’s disease, Parkinson’s disease, schizophrenia, bipolar disorder, emphysema,
and cataracts.
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o EatRight Ontario recommends that rather than taking supplements, eat a variety of
fruits, vegetables and whole grains following Canada's Food Guide.
o Vitamins are organic compounds that are essential for the growth and
maintenance of your body's normal functions.
o You need 13 Vitamins for good health.
o Vitamins are classified by their solubility which is the vitamins ability to dissolve
into another substance.
o Antioxidants are compounds that help to neutralize dangerous substances called
free radicals attacking you from inside and outside your body.
o Vitamins that have antioxidant properties include vitamins E, C, and a
precursor to vitamin A called beta-carotene.
o Vitamins are broken into two main groups: Fat-soluble vitamins, Vitamins A, D,
E and K and Water-soluble vitamins -Vitamins B and C.
o Fat-soluble vitamins are vitamins that dissolve in fat and include vitamins A, D,
E and K.
o Vitamin A helps with vision. Sources: liver, milk, carrots, and dark green
vegetables
o Vitamin D helps calcium absorption for healthy bones.
Sources: saltwater fish and egg yolks, and many times added to fortified milk
o Vitamin E helps with your immunity.
Sources: vegetable oil, nuts and seeds.
o Vitamin K is needed for blood clotting.
Source: green leafy vegetables.
o Water-soluble vitamins are vitamins that dissolve in water and include the B-
complex vitamins and Vitamin C.
o There are 8 B Vitamins including vitamin B1, B2, B3, B5, B6, B7, B9 and B12
o Each of the numbered B vitamins has a corresponding name:
o In order their names are thiamine, riboflavin, niacin, pantothenic acid,
pyridoxine, biotin, folate and cobalamin.
o To recall these names, use the mnemonic- These Riddles Need Practice,
Practice Builds Future Character.
o The B-Complex vitamins are important for energy.
Sources: fish and poultry to beans and peas.
o Vitamin C or ascorbic acid plays a role in the synthesis of Collagen and helps with
your immune system.
Sources: fruit and vegetable vitamin everything from berries to peppers, to
tomatoes.
Summary of Vitamin Functions and Sources
https://www.youtube.com/watch?v=audgTg1vyl0
Major Minerals
Calcium
Calcium is the mineral most abundant in our bodies, especially in the bones and
teeth.
It's an important electrolyte and is essential for contraction of muscles and
heartbeat. It's involved in hormones, digestive enzymes and neurotransmitters. In
North America many do not meet the daily requirements of calcium.
Sources of calcium:
o We get it from dairy (milk, cheese, yogurt, kefir, buttermilk, green leafy
vegetables or green vegetables like kale and broccoli (but not spinach, Swiss
chard as these are binding and don't allow as much absorption of calcium).
o Deficiency of calcium results in bone problems, high blood pressure, kidney
stones. Osteoporosis (thinning of bones) is a particular problem in older women-
fractures.
o As women age and go through menopause they have less estrogen.
Osteoporosis factors:
• Poor nutrition.
• Gender, genetics.
• Environmental factors (poor nutrition- not enough calcium and vitamin d)
estrogen, being underweight, those consuming alcohol or smoking, caffeine
intake, soft drink consumption, inadequate vitamin K.
Phosphorus
o Phosphorus is well supplied in our diet. It's found in cottage cheese, dairy, meats
and in high protein foods like beans, nuts and lentils.
o It's not usually one we need to worry about. It's found in our bones and teeth
and is important for acid base balance, DNA, RNA and enzymatic activities.
Magnesium
o Magnesium is wide spread in diet usually.
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o It's found in leafy greens, and legumes. Roles of magnesium include enzymatic
reactions, release of energy, metabolism, in soft tissues and muscles and
prevention of tooth decay.
o Needs for magnesium are met in most diets.
o Low intake can cause deficiency through illness, vomiting, diarrhea, protein
malnutrition, use of diuretics, or alcoholism.
o 75% of North Americans don't get enough magnesium.
o It is washed away in food processing.
Sodium
o Sodium (salt) is one mineral to be concerned with because many diets are too
high in sodium especially because of processed foods.
o It is critical as electrolyte, and for fluid balance, muscle contraction, acid-base
balance, and nerve transmission.
o Deficiency in it is unusual.
o Usually, we have more to worry about from having too much. Too limit sodium,
consider the DASH (Dietary Approaches to Stop Hypertension) diet that reduces
salt intake with a strong reliance on fruits, vegetables nuts, fish, and whole
grains.
Potassium
Sulfate
o Sulfate is required to synthesize sulfur containing compounds like some
antioxidants, Thiamin and sulfur containing amino acids.
o Usually, we do not see deficiencies.
o Excess could come from water problems.
o It is found in protein rich foods.
Iron
o Iron is important to women of child bearing age.
o Iron is in meat (heme iron) and plants (non heme), but it is absorbed differently.
Anemia is often a result of iron deficiency.
o Iron carries oxygen around the body and allows muscles to be oxygenated.
o There is an increased need during pregnancy.
o Women have greater need for iron compared to men.
o Iron deficiency is a worldwide issue.
o Some vegetarian diets may not get enough iron.
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o Meat is heme iron and is easily absorbed but plant based foods are non heme and
these are not as well absorbed.
o To boost absorption of iron, eat meat and vegetables together.
o Vitamin C helps absorb iron.
Zinc
o Zinc food sources include yogurt, cereals and meats.
o Zinc helps enzymes, and is important in pregnancy, wound healing.
o It assists in immune function and in children for growth and development.
o Deficiency of zinc creates problem with immunity; it impairs the immune
response, leading to increased infections, and it can cause night blindness.
o Zinc can disturb the thyroid. In children a deficiency results in diminished growth.
Those who need to be worried about having a zinc deficiency are pregnant
women, children, the elderly and the poor.
o We need to be careful with zinc supplementation as too much can block
absorption of other things like iron.
Selenium
For a good overview of nutrients needed in the human body see PBS
interactive http://www.pbs.org/wgbh/nova/body/nutrients-body-needs.html
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o They may be sweating and losing electrolytes. To balance that the person should eat
something.
Water Requirements:
o DRI is set to achieve 87% of day's need for water.
o For men 13 cups of water on average; for women about 9 cups.
o (8 ounce cups) or 1 ml of water per calorie.
o For a 2000 calorie diet about 2 liters per day.
o In general men should aim to drink about three liters of fluid every day; while women
should consider drinking about 2.2 liters on a daily basis.
Why might some need more water. Conditions where more water might be needed:
• Consuming alcohol
• Cold weather or hot weather or high humidity, high altitudes
• Forced-air environment or heated environment
• Physical activity
• When consuming a lot of Dietary fibre, increased protein, salt or sugar intake
• Diseases like diabetes or kidney disease, when suffering fever, diarrhea or vomiting,
surgery, blood loss or burns, those in ketosis
• Taking diuretics and other medications that remove water from the body, or after giving
blood.
• The very young or older individuals, those who are pregnant or breastfeeding.
Alcohol Metabolism
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o The majority of alcohol metabolism happens in the liver, but alcohol can also
be metabolized in other body organs such as the brain, pancreas, stomach and small
intestine.
o After consumption 20% of alcohol is absorbed through the stomach, 80% is absorbed
in the small intestine.
o The chemical name for alcohol is ethanol, which is mainly broken down in the liver.
o Liver enzymes breakdown ethanol into intermediate molecules called metabolites.
o These metabolites are then broken down into carbon dioxide and water which is
removed from the body.
Binge Drinking
o Binge drinking is as a pattern of drinking that brings blood alcohol concentration (BAC)
levels to 0.08 g/dL.
o This typically occurs after 4 drinks for women and 5 drinks for men - in about 2 hours.
o The Substance Abuse and Mental Health Services Administration (SAMHSA), which
conducts the annual National Survey on Drug Use and Health (NSDUH), defines binge
drinking as drinking 5 or more alcoholic drinks on the same occasion on at least 1 day
in the past 30 days.
Heavy Drinking
o Heavy drinking can be defined as drinking 5 or more drinks on the same occasion on
each of 5 or more days in the past 30 days.
(Source: http://www.niaaa.nih.gov/alcohol-health/overview-alcohol-
consumption/moderate-binge-drinking)
Canadian Guidelines
In 2023 the Canadian Centre on Substance Use and Addictions released their Canada’s
Guidance on Alcohol and Health:
Final Report
o "Canada’s Guidance on Alcohol and Health provides evidence-based advice on alcohol to
support people in making informed decisions about their health.
o The guidance is based on the latest research on alcohol-related risks and replaces
Canada’s Low-Risk Alcohol Drinking Guidelines (LRDGs) issued in 2011.
o Previously, The Canadian Centre on Substance Abuse (CCSA) noted women should not
drink more than two drinks a day on most days, to a maximum of 10 in a week and for
men, it’s no more than three drinks on most days to a maximum of 15 drinks a week.
This is no longer recommended.
o The guidance is based on the principle of autonomy in harm reduction and the
fundamental idea behind it that people living in Canada have a right to know that all
alcohol use comes with risk.
Key points from the guidance include:
There is a continuum of risk associated with weekly alcohol use where the risk of harm is:
o 0 drinks per week - Not drinking has benefits, such as better health, and better sleep.
o 2 standard drinks or less per week - You are likely to avoid alcohol-related
consequences for yourself or others at this level.
o 3 - 6 standard drinks per week - Your risk of developing several types of cancer,
including breast and colon cancer, increases at this level.
o 7 standard drinks or more per week - Your risk of heart disease or stroke increases
significantly at this level.
o Each additional standard drink radically increases the risk of alcohol-related
consequences.
o Consuming more than 2 standard drinks per occasion is associated with an increased
risk of harms to self and others, including injuries and violence.
o When pregnant or trying to get pregnant, there is no known safe amount of alcohol
use.
o When breastfeeding, not drinking alcohol is safest.
o No matter where you are on the continuum, for your health, less alcohol is better."
Source: https://ccsa.ca/canadas-guidance-alcohol-and-health
Alcohol Measurement
Measuring Alcohol
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Hangovers
Can You Cure A Hangover?
o Hangovers are the body's reaction to poisoning and withdrawal from alcohol.
Hangovers begin 8 to 12 hours after the last drink and symptoms include fatigue,
depression, headache, thirst, nausea, and vomiting.
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o The severity of symptoms varies according to the individual and the quantity of
alcohol consumed.
o People have tried many different things to relieve the effects of "the morning after,"
and there are a lot of myths about what to do to prevent or alleviate a hangover.
o The only way to prevent a hangover is to drink in moderation.
Avoid a hangover by:
o Eating a good dinner and continuing to snack throughout the night.
o Starting out slowly to see how the alcohol is affecting you.
o Avoiding drinking games or shots.
o Drinking a large amount of alcohol in a short amount of time is the most likely way to
become dangerously intoxicated.
Source: http://www.brown.edu/campus-life/health/services/promotion/alcohol-other-
drugs-alcohol/alcohol-and-your-bodyps://youtu.be/audgTg1vyl0