Sialadenitis Remastered

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Department of Oral Pathology

and Microbiology

Seminar on,
Sialadenitis
Submitted by,
Anandhu Sudhakaran
Third year
Contents
Sialadenitis
Acute bacterial sialadenitis
Clinical features
Histologic features
Treatment
Viral sialadenitis
Diagnosis
Differential diagnosis
Treatment
Sialdenitis
• Inflammatory disorders of the major salivary
glands are usually the result of bacterial or
viral infection but occasionally sialadenitis is
due to other causes, such as trauma,
irradiation, and allergic reactions.
Acute bacterial sialadenitis

• This uncommon disorder principally involves


the parotid gland.
• Acute paroritis is an ascending infection, the
main organisms involved being Streptococus
pyogenes and Staphyfococus aureus.
Clinical Features
• The onset of acute sialadenitis is rapid.
Clinically, it presents as swelling of the
involved gland accompanied by pain, fever,
malaise, and redness of the overlying skin.
Pus may be expressed from the affected
duct and pain is radiated to the ear and the
temporal area.
Histological Features
• shows varying degrees of
• 1. dilatation of the ductal system
• 2. hyperplasia of duct epithelium
• 3. periductal fibrosis
• 4. acinar atrophy with replacement fibrosis
• 5. chronic inflammatory cell
• The duct obstruction, destruction of glandular
tissue, and duct dilatation (sialectasia) may be
demonstrated by sialography.
Acute bacterial sialadenitis
Treatment
• Antibiotic therapy should be started early,
with amoxicillin as the agent of first choice.
• A loading dose of 3 g amoxicillin may be
prescribed prior to therapy of (250-500mg) 3
times daily for 5 days.
CHRONIC BACTERIAL SIALADENITIS
• It is a non specific inflammatory disease of the
salivary gland secondary to duct obstruction or
low grade sustained ascending infection.

Clinical features

• It frequently affects the parotid gland.


• Dilatations of the ductal system is seen.
• Hyperplasia of the ductal system.
• Periductal fibrosis.
• Chronic inflammatory cell infiltration.
CHRONIC SIALADENITIS
Viral sialadenitis
• Mumps (epidemic parotitis)
• It is the commonest cause of parotid
enlargement and the commonest of all the
salivary gland diseases.
• Although infection can occur at any age, it is
most common in childhood. The virus is
transmitted by direct contact with infected
saliva and by droplet spread, and has an
incubation period of 2-3 weeks.
• Non-specific prodromal symptoms of fever and
malaise are followed by painful swelling of
sudden onset involving one or more salivary
glands.
• In addition to salivary gland swelling, pain and
tenderness, patients may complain of headeche.
• The parotid glands are almost always involved,
bilaterally in about 70 per cent of cases, and
occasionally the submandibular and sublingual
glands may be affected, but rarely without
parotid involvement
Diagnosis
• The diagnosis of mumps is usually made on
clinical grounds,but in atypical cases can be
confirmed by the detection of IgM class
antibodies and by the rise in serum antibody
titre co mumps virus antigens which occurs
within the first week.
• After an attack immunity is long-lasting and
so recurrent infection is rare.
Differential Diagnosis

• Sarcoidosis

Tuberculosis

Actinomycosis
Treatment

• Symptomatic treatment with the use of


antipyretics, simple analgesics, fluid intake
and rest.
• Isolation is important
THANK YOU

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