F -X C h a n ge F -X C h a n ge

PD PD

!
W

W
O

O
N

N
y

y
bu

bu
to

to
k

k
lic

lic
C

C
w

w
m

m
w w
w

w
o

o
.d o .c .d o .c
c u -tr a c k c u -tr a c k

:
:
: His, Val , Asp:
: :
.( - ) Phi PH
.( + ) Phi PH
: PH Phi :
: 5.2 = PH :
. 5.2 < 7.65 :His
. 5.2 < 6.00 :Val
. 5.2 > 2.95 :Asp

:
: Gly – Lys – Asp – Ala :
: 1 = PH -
: :
Asp , Glu : ( 02 ) :
. PH
His , Arg , Lys : ( 03 ) :
. PH
. :( 15 ) :

1+ = : PH
1- (1 + )= : PH
 F -X C h a n ge F -X C h a n ge
PD PD

!
W

W
O

O
N

N
y

y
bu

bu
to

to
k

k
lic

lic
C

C
w

w
m

m
w w
w

w
o

o
.d o .c .d o .c
c u -tr a c k c u -tr a c k

.2+ : 1 = PH : Gly – Lys – Asp – Ala : :

.2- : 12 = PH : Gly – Lys – Asp – Ala :
.3+: 1 = PH : /2
. /3
:
:1 = PH
: :
2+ = Gly-Arg
1+ = Glu- Gly
2+ =Gly- Glu- Arg
-1 – 1 = PH :
: 13 = PH
1- = Gly-Arg
2- = Glu- Gly
2- =Gly- Glu- Arg
-2 – 13 = PH :
: : 7 = PH
1+ = Gly-Arg
1- = Glu- Gly
: .0 = Gly- Glu- Arg

:
:
:
trypsine Lys, Arg ( C )
chymotrypsine Trp , Phe , Tyr ( C )
pepsine Trp , Phe , Tyr ( N )
. :(N) . (C)
 F -X C h a n ge F -X C h a n ge
PD PD

!
W

W
O

O
N

N
y

y
bu

bu
to

to
k

k
lic

lic
:
C

C
w

w
m

m
w w
w

w
o

o
.d o .c .d o .c
c u -tr a c k c u -tr a c k

:
:
: : 20 =
– :
. 39 :

:
: :

:
 F -X C h a n ge F -X C h a n ge
PD PD

!
W

W
O

O
N

N
y

y
bu

bu
to

to
k

k
lic

lic
C

C
w

w
m

m
w w
w

w
o

o
.c .c

:
.d o .d o
c u -tr a c k c u -tr a c k

:PH

:
:
. 10.32 = PH
. 10.32 PH
:
. PH 10.32 = PH
PH

.... /