Vishaghana Mahakashya

Vishaghana Mahakashya.
(Ras Panchak)
1. Haridra (Turmeric) Curcuma longa
(Zingiberacae) Rasa - Tikta, Katu; Guna - Ruksha;
Virya - Ushna; Vipaka - Katu Kaphavatahara
2. Manjishtha (Indian Madder) Rubia cordifolia
(Rubiaceae) Rasa - Madhur, Tikta, Katu; Guna -
Guru; Virya - Ushna; Vipaka - Katu
3. Suvaha (Rasna) Pluchea lanceolata
(Compositae) Rasa - Tikta; Guna - Guru; Virya -
Ushna; Vipaka - Katu Vatakaphashamaka
4. Ela (Lesser Cardamom) Elettaria cardamomum
(Zingiberaceae) Rasa - Katu, Madhura; Guna -
Laghu, Snigdha, Sugandhi, Sukshma; Virya - Shita;
Vipaka - Madhur Kaphavataghna
5. Palindi (Turpeth) Operculina turpethum
(Convolvulaceae) Rasa - Katu, Tikta, Madhura,
Kashaya; Guna - Guru, Ruksha, Teekshna; Virya -
Ushna; Vipaka - Katu Pitta Kapha Sanshodhana
6. Chandan (Sandalwood) Santalum album
(Santalaceae) Rasa - Tikta, Madhura; Guna -
Laghu, Ruksha; Virya - Sheeta; Vipaka - Katu
Kaphapittashamaka
7. Katak (Clearing nut) Strychnos potatorum
(Loganiaceae) Rasa - Madhura, Kashaya, Tikta;
Guna -Laghu; Virya - Shita; Vipaka - Madhur
Vatakaphashamaka
8. Shirisha (Shirisha) Albizzia lebbeck
(Leguminosae) Rasa - Madhura, Tikta, Kashaya;
Guna -Laghu; Virya - Ushna; Vipaka - Katu
Tridoshaghna
9. Sindhuvaar (five leaves chaste) Vitex negundo
(Verbenaceae) Rasa - Tikta; Guna - Laghu, Ruksha;
Virya - Ushna; Vipaka - Katu Kaphvatshamaka
10. Shleshmatak (Sebestan) Cordia dichotoma
(Boraginaceae) Rasa - Madhura; Guna - Snigdha,
Guru, Pichchila; Virya - Ushna, Vipaka - Katu
Vatapittashamaka, Kaphavardhak
[1]There are the ten properties of poisonous

drugs. Drugs which act against toxic effect of
substances are called as Vishaghna.
[2] Vishaghanamahakashaya shows the anti-toxic
effect by treating of Rakta and Pitta Dushti. The
term Vishaghana and detoxification are same
functionally. Vishaghana Mahakashaya Dravya
denatures toxins, neutralise toxins and excretes
toxins from the body.
It includes Haridra (Curcuma longa), Manjishtha
(Rubia cordifolia), Suvahaa (Operculina
turpethum), Sukshama Ela (Elettaria
cardamomum), Paalindee (Hemidesmus indicus),
Chandan (Santalum album), Kataka (Strychnos
potatorum), Shirish (Albizzia lebbeck), Sinduvaara
(Vitex negundo) and Shleshmaataka (Cordia
dichotoma). Vishghanamahakashya has large area
of therapeutic uses. contemporary aspects. Key
words: Vishaghana Mahakashaya, Detoxification, a
Table 2: Chemical composition of each drug of
Vishghana Mahakashaya SN Vishghana Dravya
Chemical Composition
1. Haridra Curcumin, curcone, curcumenone,
cineole, eugenol[4]
2. Manjistha Mangistin, alizarin, garancin,
mollugin, furomollugin[5]
3. Suvaha Pluchine, quercetin, isohamnetin,
hesperidin[6]
4. Ela Pinene, sabinene, myrcene, limonene[7]
5. Palindi Turpethin
6. Chandan Santalol, Sesquiterpene,
7. Katak Brucine
8. Shirish Saponins and Tannins
9. Sindhuvaar Malic acid
10. Shleshmatak Tannin
Uses of Vishghana drugs in poisoning

1. Haridra: Ghee cooked with Haridra is best to
treat artificial poison.[8] It is locally used in
rat bite.[9] Fresh turmeric rhizome, Ankolam
root and Nirgundi paste applied locally on dog
bite. Paste made of fresh turmeric rhizome
and Moringa oleifera bark is applied on
injured portion of dog bite. It is used for an
external application with human milk in leech
poisoning.
Haridra with Gomutra cures sea snake bite.
Decoction of Haridra with milk cures all types
of poisons.
Intake of Haridra with Gomutra cures all
animate and inanimate poisons.
Turmeric mixed with Saindhav, honey and
Ghee is useful for poisoning by root poison
and also in person wounded by poisoned
weapon.
2. Manjistha: Rubia cordifolia shows antioxidant
activity against lead nitrate and radiation
induced toxicity.Purpurin constituents of
Rubia cordifolia shows antigenotoxic
activity.According to Bhavaprakash,
Manjishtha is able to bind itself Amavisha and
Garavisha.
3. Rasna: It is used in Lepa for poisoned hands.
It is used in treatment of spider bite.
4. Ela: It is used in lead poisoning.The aqueous
cardamom suspension can enhance
detoxifying enzyme and decrease
peroxidation of lipid.
5. Sariva: It is used in hepatotoxicity.
6. Chandan: Useful for an external application
on cardiac region in poisoning by fumes.
Consumption of Chandan and Amalaki mixed
with honey in morning cures artificial
poisoning.
7. Katak: It is used in Lepa for massage by
poisoned oil.Katak is used as Lepa in Vataj
Loota Visha.It is an antidote for hot honey.
8. Shirish: Shirish is the best drug of choice of
poisoning.It is used in Pradeha for poisoning
by poisoned ornaments.Three times
macerated seeds of Shirisha in calotropis latex
mixed with Pippali powder are useful in
insect, spider, snake, scorpion and rat bite.It is
useful in anointing the swollen gums due to
poisoned tooth-brush.
9. Sinduvar: it is useful in Darvikar Visha for
internal administration.Sinduvaradi Kwath
useful in rat poisoning.
10. Shleshmantak: It is useful in all types of
spider poisoning.It is present in Pradeha
useful in poisoning by feet and seat. It
reduces adverse effect of Adriamycin.
Vishaghana drugs Classification according to
Charak Sushruta Vagbhat Contemporary uses
1. Haridra- Kusthaghana Lekhaniya, Kandughana,
Vishaghana, Shirovirecha na Haridradi Gana,
Mustadi Gana Antiinflammatory, anti-oxidant,
antidiabetic, antihistaminic blood purifier,
immunomodulator
2. Manjishtha - Vishghana, Jwarahara, Varnya
Priyangvadi Gana , Antimicrobial, antioxidant,
astringent
3. Suvaha - Vayasthapan a, Abhayadi Varga -
Antiinflammatory, Antipsoriatic
4. Ela- Shwasahara, Shirovirechana, Angmardapr
ashmana , Eladi, Trijatak, Chaturjatak Antiseptic,
antimicrobial, antispasmodic, antitoxic
5. Palindi- Bhedniya Syamadi , Antiinflammatory,
antihelminthic, purgative, antihistaminic
6. Chandan- Varnya, Kandughana, Dahaprasha
mana, Trishnanigrahana, Salasaradi, Sarivadi,
Patoladi, Guduchyadi, Priyangvadi ,Diuretic,
antiseptic, antitoxic
7. Katak - Vishaghana Parusakadi Antidiabetic,
Antimicrobial, Antiarthrtic
8. Shirisha- Vednasthapana, Shirovirechana
Salasaradi, Asanadi, Antiseptic, Antibacterial,
Antisnake venom
9. Sinduvar - Krimighana Surasadi Antiseptic,
Antioxidant, Insecticidal
10 Shleshmantak - Vishaghana ,Phala Varga
Diuretic, Antiinflammatory, Antimicrobial
Vishaghana Mahakashya helps to treat all types of

poisons like snake bite, rat bite, dog bite, Gara
Visha, Dushi Visha, adverse drug reactions.
Drugs of Vishaghana Mahakashya having

properties of Vishaghana. It includes Haridra
(Curcuma longa), Manjishtha (Rubia cordifolia),
Suvaha (Operculina turpethum), Sukshama ela
(Elettaria cardamomum), Palindi (Hemidesmus
indicus), Chandan (Santalum album), Kataka
(Strychnos potatorum), Shirish (Albizzia lebbeck),
Sinduvaara (Vitex negundo) and Shleshmataka
(Cordia dichotoma).
These drugs show antitoxic effect by removing and
neutralising toxins in the body at cellular level. As
per modern scenario Vishaghana Mahakashya
have properties like antibacterial, anti-fungal, anti-
histaminic etc. so we can use this in our daily to
daily life.
Action against poison in Vishaghana Mahakashya
1. Haridra: It cleanses and purifies Rakta. It works
as Rakta Shodhan as well as Rakta Prasadhan.
Gara Visha vitiates Rakta Dhatu, Haridra being
Tikta Rasa counteracts Gara Visha localised in
blood.
2. Manjistha: Manjistha is selected in
Mahakashaya mainly by its blood purifying
property. It is having Tikta, Kashya and Madhur
Rasa so it purifies Rakta Dhatu.
3. Suvaha: Trivrit is best indicated as mild laxative
so it removes poison through purgation.
4. Ela: Ela has Madhur and Katu Rasa, Madhur
Vipaka and cold potency, so having opposite
qualities it works as Vishaghana.
5. Palindi: It has Madhur and Katu Rasa, Madhur
Vipaka and cold potency.
6. Chandan: It has Tikta Rasa and cold potency
Chandana counteracts with astringent and hot
properties of Visha.
7. Katak: It increases the production of urine so it
drains out poison through urine. Katak is Laghu,
Vishada, Madhura, Tikta, Kashaya and has cold
potency.
8. Shirish: Shirish is best anti-poisonous drug. It is
Vishaghana by its Prabhav.
9. Sinduvar: It is Laghu and Ruksha, Katu and Tikta
in taste, Katu in Vipaka and hot in potency so it
has Vata relieving property, it is used in
Darvikaradi Vata aggravating Visha.
10. Shleshmantak: It is specially used in spider
poisoning.

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Vishaghana Mahakashya.

[1]There are the ten properties of poisonous

Uses of Vishghana drugs in poisoning

Vishaghana Mahakashya helps to treat all types of

Drugs of Vishaghana Mahakashya having

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