PHAR1015-SomeExtraPracticeSAQs 2021
PHAR1015-SomeExtraPracticeSAQs 2021
PHAR1015-SomeExtraPracticeSAQs 2021
Exercise One
Mrs CL is a 90 year old lady who is 165 cm tall and weighs 78 kg. A serum creatinine is
measured for her at 90 micromol/L.
Provide an appropriate dosage adjustment, if required, for the following prescriptions. (If no dose
adjustment is required, then specify so.) (Don’t worry, she’s not taking them all at once!)
This exercise uses an infectious disease you may or may not remember (it was covered in RTI!).
Regardless of the specific infection, don’t panic - the principles of antimicrobial therapy are the
same as what we’ve been talking about in this course.
Mr PP is a 92 year old elderly man who lives in a nursing home. He has a history of stroke,
and as such has difficulty swallowing. He requires his food to be administered in puree
form as his swallowing difficulties present a risk of aspiration - the accidental inhalation of
food. He is 168cm tall and weighs 76kg.
The practitioner seeing him in the emergency department wrote the following notes:
Mr TS, elderly gentleman, lives in N/home due to requiring significant care after a stroke 2
years ago
Presenting Complaint:
Medicines:
Allergies:
- Nursing home report mild rash 1 week after starting cefalexin (5 years ago)
Nurses witnessed a significant aspiration of lunch a few days ago. Since then has developed a
cough, fever and confusion.
On examination:
Confused. Abdomen and chest clear. Lungs have one lobe with poor air-entry.
Blood Pressure: 86/60 mmHg, Heart Rate 120 beats/minute, Temperature: 38.7oC.
Assessment:
ASPIRATION PNEUMONIA – ESTABLISHED (NOT RESPONDING TO EMPIRICAL
CAP THERAPY).
Your task:
Identify an appropriate antibiotic regimen, including dose, route and frequency for Mr PP.
Explain and justify your selection, including a comment about the severity of infection.
Exercise 3
Select an appropriate drug, dose, route and frequency for the following situations:
23 year old man, otherwise healthy, with an acute lower UTI. His urine has grown a
culture of Pseudomonas aeruginosa. No adverse drug reactions known. (this one is a
‘tough one’)
33 year old pregnant female with a lower UTI. No organism is grown. No adverse drug
reactions known.
54 year old female, otherwise healthy with Staph cellulitis. No obvious signs of sepsis.
She has had a reaction to penicillin in the past, it caused DRESS.