Human Reproduction
Human Reproduction
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OVARIES CERVIX AND VAGINA
• They are the primary female sex organs. • The cervix connects the uterus to the vagina.
They produce the ovum and other ovarian • The cervix and the vagina constitute the birth
hormones. canal.
• Each ovary is covered by epithelium, and o Mons pubis − Fatty tissue covered by skin
contains the ovarian stroma. and pubic hair
• The ovarian stroma is made up of: o Labia majora − Extends from mons pubis
and surrounds the vaginal opening
o Peripheral cortex
o Inner medulla o Labia minora − Fold of skin beneath the
labia majora
• The uterine wall consists of: The testis and ovary produce the male and
female gametes respectively by
o External perimetrium
gametogenesis (spermatogenesis in males
o Middle myometrium and oogenesis in females).
o Internal endometrium, which lines the
uterine cavity
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SPERMATOGENESIS STRUCTURE OF A SPERM
o Head
• In males, sperms are produced by the o Neck
spermatogonia (immature germ cells), o Middle piece
which are present in the inner walls of the o Tail
seminiferous tubules. • The whole sperm is enclosed in a plasma
• Spermatogonia increase in number by membrane.
mitosis. These are diploid.
• The head consists of a haploid nucleus and a
• Some of the spermatogonia called primary caplike acrosome , which contains enzymes
spermatocytes periodically undergo meiosis. that aid in fertilisation.
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• Before reaching puberty, a large number of
• It is followed by the follicular phase .In this
primary oocytes degenerate and the
remaining ones get surrounded by layers of phase, the primary follicles mature into the
granulosa cells and new theca and are called Graffian follicles. This causes the regeneration
secondary follicles. of the endometrium. These changes are
brought about by ovarian and pituitary
• The secondary follicles are then converted hormones. In this phase, the release of
into tertiary follicles that have characteristic
gonadotropins (LH and FSH) increases. This
fluidfilled cavity called antrum. At this stage,
the primary oocyte present within the tertiary causes follicular growth and the growing
follicle completes meiosis, which results in the follicles produce oestrogen.
formation of haploid secondary oocyte and a
tiny polar body. • The LH and FSH are at their peak in the middle
of the cycle (14 th day), and cause the
• This tertiary follicle further changes into the
Graafian follicle . The secondary oocyte is rupture of the Graffian follicles to release
surrounded by the zone pellucida. ovum. This phase is called the ovulatory
phase.
• Then the Graafian follicle ruptures to release
the ovum by ovulation
• The remains of the Graffian follicles get
converted into the corpus luteum, which
MENSTRUAL CYCLE & FERTILISATION secretes progesterone for the maintenance
of the endometrium
• During the middle of the menstrual cycle, • The process of fusion of the sperm and the
one ovum is released (ovulation). ovum is known as fertilisation.
• The cycle starts with the menstrual flow • During fertilisation, the sperm induces
(3 to 5 days), caused due to the breakdown changes in the zona pellucida and blocks the
of the endometrium of the uterus. Blood entry of other sperms. This ensures that only
vessels in liquid state are discharged, but this one sperm fertilises an ovum.
occurs only when the ovum is not fertilised.
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• The enzymatic secretions of the acrosomes
• These hormones support foetal growth and
help the sperm enter the cytoplasm of the
ovum. help in the maintenance of pregnancy.
Hormones like oestrogen, progestogen,
• This causes the completion of meiotic cortisol, prolactin, etc., are increased several
division of the secondary oocyte, resulting in folds in the maternal blood.
the formation of a haploid ovum (ootid) and
a secondary polar body.
• Immediately after implantation, the inner cell
• Then, the haploid sperm nucleus fuses with mass (embryo) gets differentiated into the
the haploid nucleus of the ovum to form a ectoderm, mesoderm and endoderm, which
diploid zygote . give rise to the different tissues. This ability of
the inner cell mass is due to the presence of
• Mitosis starts as the zygote moves through
multipotent cells called stem cells .
the isthmus of the oviduct (cleavage) and
forms 2, 4, 8, 16 daughter cells called
blastomeres . • Most of the major organs are formed at the
end of 12 weeks of pregnancy; during the 5 th
• The 8−16 cell embryo is called a morula , month, the limbs and body hair are formed;
which continues to divide to form the by the 24 th week, the eyelids separate and
blastocyst . The morula moves further into the
eyelashes are formed. At the end of nine
uterus.
months, the foetus is fully formed.
• The cells in the blastocyst are arranged into
an outer trophoblast and an inner cell mass .
PARTURITION AND LACTATION
• The trophoblast gets attached to the uterine
endometrium, and the process is called
implantation. This leads to pregnancy. • Human pregnancy has the duration of 9
months. This duration is called the gestation
• The inner cell mass gets differentiated to period
form the embryo.
• At the end of this period, vigorous uterine
contractions lead to the delivery of the foetus.
PREGNANCY, PARTURITION AND This process is called parturition