Paper 4
Paper 4
Paper 4
Cambridge IGCSE™
* 0 8 8 3 9 1 5 6 0 7 *
BIOLOGY 0610/41
Paper 4 Theory (Extended) May/June 2020
1 hour 15 minutes
INSTRUCTIONS
● Answer all questions.
● Use a black or dark blue pen. You may use an HB pencil for any diagrams or graphs.
● Write your name, centre number and candidate number in the boxes at the top of the page.
● Write your answer to each question in the space provided.
● Do not use an erasable pen or correction fluid.
● Do not write on any bar codes.
● You may use a calculator.
● You should show all your working and use appropriate units.
INFORMATION
● The total mark for this paper is 80.
● The number of marks for each question or part question is shown in brackets [ ].
DC (ST/CT) 180481/3
© UCLES 2020 [Turn over
2
1 The gas exchange system is one of the organ systems of the human body.
Fig. 1.1 shows parts of the gas exchange system during breathing in and breathing out.
intercostal
muscles
vertebrae
sternum
diaphragm
Fig. 1.1
• the functions of the diaphragm and the intercostal muscles during breathing in and
breathing out
• the pressure changes in the thorax.
contract
relax
increases
decreases.
Table 1.1
breathing in
breathing out
[4]
movement of air
magnification ×350
Fig. 1.2
(b) State two features of the gas exchange surface that are visible in Fig. 1.2.
1 ................................................................................................................................................
2 ................................................................................................................................................
[2]
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
[Total: 10]
2 Biological washing powders contain enzymes that break down food stains.
(a) Complete Table 2.1 by naming the enzymes that break down three substances in food stains
and by stating the product or products.
Table 2.1
starch
fat
protein
[3]
Some students compared how effective biological and non-biological washing powders are at
removing stains at temperatures between 10 °C and 60 °C.
• Pieces of stained cloth were washed using two different washing powders.
• The degree of stain removal was measured by using a light meter to record the
percentage of light reflected from the cloth.
• A light meter gave a value of 100% when the cloth was completely clean.
• Any stain left on the cloth reduced the percentage of light reflected.
110
100
90
percentage
of light 80
reflected
after 70
washing
60
50
40
10 20 30 40 50 60 70
temperature of washing / °C
Key:
non-biological washing powder
biological washing powder
Fig. 2.1
(b) Compare the effectiveness of the two washing powders at removing stains.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
............................................................................................................................................. [4]
(c) The students suggested that the enzymes in the biological washing powder were denatured
at high temperatures.
Explain why enzyme molecules do not function when they are denatured.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
............................................................................................................................................. [2]
(d) Forensic scientists often try to find DNA on items of stained clothing. The DNA can be used to
identify individual people.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
............................................................................................................................................. [2]
[Total: 11]
3 (a) Dialysis tubing is an artificial membrane, which is similar to the lining of the intestine.
A student investigated the diffusion of glucose through dialysis tubing by using the apparatus
shown in Fig. 3.1.
rubber band
to secure the
dialysis tubing
glucose solution
water outside
the dialysis tubing
dialysis tubing
Fig. 3.1
The student took samples of the water outside the dialysis tubing at 5 minute intervals and
tested the samples with Benedict’s solution.
Table 3.1
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [3]
(ii) The student repeated the investigation with a higher concentration of glucose in the
dialysis tubing.
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [1]
(b) Fig. 3.2 shows a drawing of a cell from the lining of the small intestine. The lumen is the
space inside the intestine where food is digested.
not to scale
Fig. 3.2
State the names of the three labelled structures in Fig. 3.2 and describe the role of each
structure in the intestinal cell.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
............................................................................................................................................. [6]
(c) The cholera bacterium can survive in the small intestine and the large intestine. The bacterium
releases a toxin that interacts with receptors on the surface of cells.
Fig. 3.3 shows the effect of the toxin. The arrows indicate the direction of movement.
Key:
toxin
ion X
not to scale
Fig. 3.3
The toxin stimulates the secretion of ion X out of the intestinal cell.
..................................................................................................................................... [1]
(ii) Describe the effects on the body of the secretion of ion X into the lumen of the intestine.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [4]
[Total: 15]
BLANK PAGE
Fig. 4.1
..................................................................................................................................... [1]
(ii) Describe two features visible in Fig. 4.1 that show that Johnson grass flowers are
adapted for wind-pollination.
1 ........................................................................................................................................
...........................................................................................................................................
2 ........................................................................................................................................
...........................................................................................................................................
[2]
(b) Fig. 4.2 shows a section through a carpel shortly after pollination.
B
A
Fig. 4.2
(i) State the names of the parts of the carpel labelled C, D and E.
C ........................................................................................................................................
D ........................................................................................................................................
E ........................................................................................................................................
[3]
Pollen grains are formed in anthers. During their formation the number of chromosomes
(c) Discuss the advantages of sexual reproduction to a wild population of flowering plants such
as Johnson grass.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
............................................................................................................................................. [5]
1 ................................................................................................................................................
2 ................................................................................................................................................
3 ................................................................................................................................................
[3]
[Total: 21]
5 Ciliates are classified in the kingdom Protoctist. Bacteria are classified in the kingdom Prokaryote.
(a) State two structural features that distinguish the cells of a protoctist from a prokaryote.
1 ................................................................................................................................................
...................................................................................................................................................
2 ................................................................................................................................................
...................................................................................................................................................
[2]
(b) Fig. 5.1 shows five species of ciliate that are found in sewage treatment works.
cilia
rows of
cilia
A Chilodonella B Didinium
cilia
fused
together
not to scale
Fig. 5.1
Fig. 5.2 is a dichotomous key to identify the ciliates shown in Fig. 5.1.
START
yes
1 has a ring of cilia at yes 2 organism B
one end of the no
organism organism E
no
4 yes
organism A
no
organism C
Fig. 5.2
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
[2]
(c) Didinium is a predatory ciliate. A video recording was made of one Didinium feeding on a
Paramecium. Fig. 5.3 shows a sequence of still photographs taken from the video.
Didinium
Paramecium
Fig. 5.3
Complete the table by putting a tick (✓) by each characteristic of life that can be seen in the
still photographs from the video in Fig. 5.3.
excretion nutrition
growth reproduction
movement respiration
[1]
(d) Fig. 5.4 is a food web for some of the microorganisms in a sewage treatment works.
Didinium
Vorticella
Fig. 5.4
(i) Construct one food chain with three trophic levels that use energy derived from the
breakdown of sewage. Do not draw the organisms.
..................................................................................................................................... [1]
© UCLES 2020 0610/41/M/J/20
17
(ii) The water that passed out of the sewage works was often cloudy with suspended matter.
Scientists discovered that ciliates reduce the cloudiness of water during sewage
treatment.
Suggest how the ciliates reduce the cloudiness of the water using the information in
Fig. 5.4.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [3]
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [3]
[Total: 14]
6 Colour blindness is a characteristic that is inherited. Colour blindness is more common in males
than in females.
Fig. 6.1 is a pedigree diagram showing the inheritance of colour blindness in a family.
Key:
male with normal
colour vision
male with colour
blindness
1 2
female with normal
colour vision
3 4
5 6 7 8
Fig. 6.1
...................................................................................................................................................
...................................................................................................................................................
............................................................................................................................................. [1]
(b) (i) Using the symbols B and b, state the genotypes of individual 5 and individual 8 in the
pedigree diagram.
5 ........................................................................................................................................
8 ........................................................................................................................................
[3]
(ii) Individual 3 is a carrier of colour blindness because she has one copy of the allele for
colour blindness but has normal colour vision.
Describe the evidence from Fig. 6.1 that shows that individual 3 is a carrier.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [3]
(iii) There was no history of colour blindness in the parents and grandparents of individuals 1
and 2.
Suggest how colour blindness first occurred in the family in Fig. 6.1.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
[Total: 9]
BLANK PAGE
Permission to reproduce items where third-party owned material protected by copyright is included has been sought and cleared where possible. Every
reasonable effort has been made by the publisher (UCLES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the
publisher will be pleased to make amends at the earliest possible opportunity.
To avoid the issue of disclosure of answer-related information to candidates, all copyright acknowledgements are reproduced online in the Cambridge
Assessment International Education Copyright Acknowledgements Booklet. This is produced for each series of examinations and is freely available to download
at www.cambridgeinternational.org after the live examination series.
Cambridge Assessment International Education is part of the Cambridge Assessment Group. Cambridge Assessment is the brand name of the University of
Cambridge Local Examinations Syndicate (UCLES), which itself is a department of the University of Cambridge.