NUR 207 Microbiology Sep-Dec 2020

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THE CATHOLIC UNIVERSITY OF EASTERN AFRICA

A. M. E. C. E. A P.O. Box 62157


00200 Nairobi - KENYA
Telephone: 891601-6
MAIN EXAMINATION Ext 1022/23/25
Fax: 254-20-891084
email:det@cuea.edu
SEPTEMBER – DECEMBER 2020 TRIMESTER exams@cuea..edu
directorofexams@cuea.edu
SCHOOL OF NURSING

REGULAR PROGRAMME

NUR 207: MICROBIOLOGY

Date: DECEMBER 2020 Duration: 3Hours


INSTRUCTIONS:
1. Answer all questions
2. Candidates are advised not to write on the question paper
3. Candidates must hand in their answer booklets to the invigilator while in
the examination room

SECTION A: MULTIPLE CHOICE QUESTIONS (20 Marks)


Q1. What is the mode of action of Sulfonamides?
a) Inhibit metabolic pathways
b) Inhibit DNA synthesis
c) Lyse cytoplasmic membrane
d) Inhibit protein synthesis

Q2. Methicillin resistant strain of Staphylococcus aureus(MRSA). Is the strain


a) susceptible to oxacilin
b) susceptible to penicillin
c) can be killed by vancomycin
d) resistant to methicillin but susceptible to other beta-lactams

Q3. Clostridium tetanicauses the disease tetanus:


a) by toxin produced by vegetative cells that germinate from spores contaminating
the wound
b) After the biting of animal that has tetanus
c) By spores
d) By producing the necrosis

Q4. An expectant lady develops septicemia. Blood cultures produce a small, motile, β-
hemolytic, Gram positive rod that does not form spores. Identify the
microorganism.
a) Listeria monocytogenes
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b) Bacillus anthracis
c) Clostridium perfringens
d) Clostridium tetani

Q5. Which toxin acts on the neuromuscular junction by inhibiting the release of
acetylcholine?
a) Cholera
b) Tetanus
c) Botulinum
d) Diphtheria

Q6. Formation of a grayish membrane in the back of the throat is seen in:
a) Diptheria
b) Pharyngitis
c) Tuberculosis
d) Pertussis

Q7. An elderly hospitalized patient has developed lobar pneumonia. Which of the
following organisms could be suspected?
a) Haemophilus influenza
b) Klebsiella pneumonia
c) Streptococcus pyogenes
d) Proteus vulgaris

Q8. A 30-year-old lady has non-bloody diarrhea for the past 14 hours. Which one of
the following organisms is least likely to cause this illness?
a) Streptococcus pyogenes
b) Clostridium difficile
c) Shigelladysenteriae
d) Salmonella enteritidis

Q9. A patient has fever, difficulty breathing, chest pains, fluid in the alveoli, and a
positive tuberculin skin test. Gram-positive cocci are isolated from the sputum. The
patient most likely has:
a) Tuberculosis
b) Influenza
c) Pneumococcal Pneumonia
d) Mycoplasmal Pneumonia

Q10. Which Escherichia coli causes diarrhea in children and travelers?


a) Enteropathogenic
b) Enterrohemorrhagic
c) Enterotoxigenic
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d) Enteroinvasive

Q11. Which of the following properties is not seen in the members of the family
Enterobacteriaceae? They
a) are catalase positive
b) are oxidase-positive
c) do ferment glucose
d) reduce nitrates to nitrites

Q12. The most common cause of urinary tract infection in a community is;
a) Proteus vulgaris
b) Citrobacter
c) Escherichia coli
d) Klebsiella pneumonia

Q13. Which of the following diseases causes a skin rash, hair loss, malaise and fever?
a) Gonorrhea
b) Syphilis
c) Nongonococcal urethritis
d) Trichomoniasis

Q14. Treponemapallidum cannot be demonstrated by microscopy in:


a) Primary syphilis
b) Secondary syphilis
c) Congenital syphilis
d) Latent syphilis

Q15. Latent syphilis is associated with all the following except?


a) The presence of clinical lesion
b) Negative dark-field examinatio
c) Positive non-treponemal serological test
d) Positive treponemal serological test

Q16. Ringworm of the foot is also called


a) Tineamanuum
b) Tineaunguinum
c) Tineapedis
d) Tineacorporis

Q17. The coronavirus disease is not transmitted by?


a) Direct contact
b) Respiratory droplet
c) Close contact
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d) Biological vector

Q18. Herpes simplex 1 usually causes ____, and herpes simplex 2 usually causes __
a) cold sores/ genital herpes
b) canker sores/ fever blisters
c) fever blisters/ cold sores
d) shingles/ stomatitis

Q19. Which of the following conditions is not associated with AIDS?


a) Pneumocystis jirovecii pneumonia
b) Kaposi sarcoma
c) dementia
d) adult T-cell leukemia

Q20. A cancer caused by Epstein-Barr virus


a) Burkitt’s lymphoma
b) Kaposi’s sarcoma
c) Hepatic carcinoma
d) Cervical cancer

SECTION B: SHORT ANSWER QUESTIONS (40 Marks)

Q1. Briefly show the pathogenesis of Neisseria gonorrhea (5 Marks)

Q2. Fill the following table: (7 Marks)

Causative Clinical Name of Route of Age of How many


agent disease vaccine administrat child times it is
ion given?
a) Polio
b) Diarrhea
c) Influenza
Hepatitis
d) Polio
e) Yellow
fever
f) Measles
g) Cervical
cancer

Q3. Indicate the mode of action of the following antibiotics: (4 Marks)


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a) Amphotericin B
b) Tetracycline
c) Sulphonamides
d) Quinolones

Q4. Use a sketch diagram to describe the various types of Enterobacteriaceae


antigens (3 Marks)

Q5. Classify bacteria of the Genus Streptococci using hemolytic reactions (4


Marks)

Q6. Describe the candida disease in men and women (5 Marks)

Q7. Outline the steps involved in viral replication (6 Marks)

Q8. Discuss the pathogenesis and clinical manifestation of HIV virus


(6 Marks)

SECTION C: ESSAY (40 Marks)

Q1.
a) Is coronavirus an RNA or DNA virus? What do you understand by this? (4
Marks)
b) Discuss the following: portals of entry and transmission of Coronavirus (8
Marks)
c) Name the cervical cancer causing virus. Describe the pathogenicity, and
clinical features and prevention of this virus (8 Marks)

Q2.
a) Outline the transmission and prevention measures for typhoid in humans.
(4 Marks)
b) Discuss tuberculosis in regard to distribution, pathogenesis, clinical features
and treatment. (8 Marks)
c) Discuss Influenza virus in regard to pathogenesis and clinical disease
(8 Marks)

*END*

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