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    Ca Larynx

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    Tito P
    This document provides an overview of laryngeal cancer, including its anatomy, incidence, risk factors, symptoms, subtypes, staging, diagnosis, and treatment options. It notes that laryngeal cancer most commonly affects males over females in a 4:1 ratio and that over 90% of cases are squamous cell carcinoma. Treatment may involve radiotherapy, chemotherapy, targeted therapy, or surgery depending on the cancer's stage, with options ranging from transoral laser microsurgery to partial or total laryngectomy. Voice restoration after total laryngectomy can be achieved through esophageal speech, tracheoesophageal puncture, or an electrolarynx.

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    Ca Larynx

    Uploaded by

    Tito P
    89 views36 pages
    This document provides an overview of laryngeal cancer, including its anatomy, incidence, risk factors, symptoms, subtypes, staging, diagnosis, and treatment options. It notes that laryngeal cancer most commonly affects males over females in a 4:1 ratio and that over 90% of cases are squamous cell carcinoma. Treatment may involve radiotherapy, chemotherapy, targeted therapy, or surgery depending on the cancer's stage, with options ranging from transoral laser microsurgery to partial or total laryngectomy. Voice restoration after total laryngectomy can be achieved through esophageal speech, tracheoesophageal puncture, or an electrolarynx.

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    ca larrynx

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    Ca larynx

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    This document provides an overview of laryngeal cancer, including its anatomy, incidence, risk factors, symptoms, subtypes, staging, diagnosis, and treatment options. It notes that laryngeal cancer most commonly affects males over females in a 4:1 ratio and that over 90% of cases are squamous cell carcinoma. Treatment may involve radiotherapy, chemotherapy, targeted therapy, or surgery depending on the cancer's stage, with options ranging from transoral laser microsurgery to partial or total laryngectomy. Voice restoration after total laryngectomy can be achieved through esophageal speech, tracheoesophageal puncture, or an electrolarynx.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    89 views36 pages

    Ca Larynx

    Uploaded by

    Tito P
    This document provides an overview of laryngeal cancer, including its anatomy, incidence, risk factors, symptoms, subtypes, staging, diagnosis, and treatment options. It notes that laryngeal cancer most commonly affects males over females in a 4:1 ratio and that over 90% of cases are squamous cell carcinoma. Treatment may involve radiotherapy, chemotherapy, targeted therapy, or surgery depending on the cancer's stage, with options ranging from transoral laser microsurgery to partial or total laryngectomy. Voice restoration after total laryngectomy can be achieved through esophageal speech, tracheoesophageal puncture, or an electrolarynx.

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    You are on page 1of 36

    1

    Anatomy
    Incidence
    Risk factors
    Symptoms
    Subtypes
    Staging
    Diagnosis
    Treatment

    2
    ANATOMY OF THE LARYNX
    The larynx is an organ in the throat.
    Its at the front of your neck.

    Its cartilages. *

    It consists of three main parts.*

    It has 2 groups of muscles


    Extrinsic & Intrinsic.
    CANCER CELLS
    INCIDENCE
    Larynx CA. is the most common
    head & neck cancer.
    Male: female = 4:1
    >90% squamous cell cancer.
    Glottic CA most common in
    Caucasian.
    Glottic CA = supraglottic in African
    American.
    RISK FACTORS
    Tobacco smoking

    Alcohol

    HPV infection in the throat

    The backward flow of


    liquid from the stomach
    to the throat.
    SYMPTOMS
    1- Changes to voice
    2- Swelling or lump in neck or throat.
    3- Difficulty swallowing.
    4- Earache that doesnt get better.
    5- Feeling breathless.
    6- Cough that doesnt go away.

    9
    SUBTYPES
    1- Supraglottic cancer : 40%
    2- Glottic cancer : 59%
    3- Subglottic cancer: 1%

    10
    STAGING
    Early cancer: Stage 0, 1, or 2

    Stage 0 Stage 1
    11
    STAGING
    Advanced cancer: Stage 3 or 4

    Stage 3
    12
    13
    DIAGNOSIS

    History

    Physical
    examination
    Indirect
    laryngoscopy

    Direct
    laryngoscopy

    Biopsy
    CT and MRI
    TREATMENT

    Before Treatment

    19
    TREATMENT

    Methods:
    1. Radiotherapy
    2. Chemotherapy
    3. Targeted therapy
    4. Surgery

    Choice of Treatment
    20
    Radiotherapy

    When is it used?

    Side effects

    21
    22
    Chemotherapy
    For patients of advanced stage
    laryngeal cancer

    Side effects

    23
    Targeted Therapy

    Maybe given with radiotherapy

    Much more specific than chemotherapy

    Cetuximab: the first approved targeted


    therapy for Laryngeal cancer

    24
    SURGICAL OPTIONS

    25
    Surgery

    Trans- oral laser microsurgery

    Laryngectomy
    Partial laryngectomy
    Total laryngectomy

    26
    TOTAL LARYNGECTOMY

    Indications:
    T3 or T4 unfit for partial

    Extensive involvement
    of thyroid and cricoid
    cartilages

    Invasion of neck soft tissues

    27
    Total laryngectomy specimen

    28
    29
    Post total laryngectomy

    30
    VOICE RESTORATION

    Esophageal speech

    Tracheo-esophageal puncture

    Electrolarynx

    31
    Esophageal speech

    32
    Tracheo-esophageal puncture
    (TEP)

    33
    34
    Electrolarynx

    35
    36

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