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    Inflammatory Bowel Disease

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    Adelina Prisca Larasati
    Inflammatory bowel disease (IBD) includes ulcerative colitis and Crohn's disease, which are chronic inflammatory conditions of the gastrointestinal tract. The document discusses the incidence, symptoms, signs, investigations, management, and oral manifestations of IBD. Key points include that the etiology of IBD is unknown, it commonly presents with abdominal pain and diarrhea in young adults, and treatment involves medications to reduce inflammation or surgery in severe cases. Oral signs of IBD can include ulcers, swelling, and tags in the mouth.

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    Inflammatory Bowel Disease

    Uploaded by

    Adelina Prisca Larasati
    127 views32 pages
    Inflammatory bowel disease (IBD) includes ulcerative colitis and Crohn's disease, which are chronic inflammatory conditions of the gastrointestinal tract. The document discusses the incidence, symptoms, signs, investigations, management, and oral manifestations of IBD. Key points include that the etiology of IBD is unknown, it commonly presents with abdominal pain and diarrhea in young adults, and treatment involves medications to reduce inflammation or surgery in severe cases. Oral signs of IBD can include ulcers, swelling, and tags in the mouth.

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    INFLAMMATORY BOWEL DISEASE.pptx

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    Inflammatory bowel disease (IBD) includes ulcerative colitis and Crohn's disease, which are chronic inflammatory conditions of the gastrointestinal tract. The document discusses the incidence, symptoms, signs, investigations, management, and oral manifestations of IBD. Key points include that the etiology of IBD is unknown, it commonly presents with abdominal pain and diarrhea in young adults, and treatment involves medications to reduce inflammation or surgery in severe cases. Oral signs of IBD can include ulcers, swelling, and tags in the mouth.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    127 views32 pages

    Inflammatory Bowel Disease

    Uploaded by

    Adelina Prisca Larasati
    Inflammatory bowel disease (IBD) includes ulcerative colitis and Crohn's disease, which are chronic inflammatory conditions of the gastrointestinal tract. The document discusses the incidence, symptoms, signs, investigations, management, and oral manifestations of IBD. Key points include that the etiology of IBD is unknown, it commonly presents with abdominal pain and diarrhea in young adults, and treatment involves medications to reduce inflammation or surgery in severe cases. Oral signs of IBD can include ulcers, swelling, and tags in the mouth.

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    You are on page 1of 32

    1

     Inflammatory bowel disease (IBD) is a


    general classification of inflammatory
    processes that affect the large and small
    intestines.
     Ulcerative colitis and Crohn’s disease
    together make up IBD.
     Etiology remains unknown  idiopathic
    IBD

    2
     Annual insidence ulcerative colitis in
    North America is 19.2 cases per 100,000
    person-years
     Crohn’s disease the annual incidence is
    20.2 cases per 100,000 person-years
     Incidence rates for both diseases are
    higher in urban areas than in rural areas
     Crohn’s disease less common than UC

    3
     1st age group 20-24 y.o, 2nd age group
    40-44y.o, 3rd age group 60-64 y.o
     Female 30% >>>
     >> in Caucasian, Jewish, North
    European, Poland, Russian

    4
    5
     Ulcerative colitis is a chronic, or long
    lasting, disease that causes inflammation
    called ulcers on the inner lining of the
    large intestine and colon.

    6
    Genetic Microorganism Imunologic

    Psychologic Environment

    7
    8
    . • Fever
    • Abdominal • Tachychard • Intestinal

    EXTRAINTESTINAL

    INTRAINTESTINAL
    SUBJECTIVE

    pain • Postural movement


    • Blood Hypotension • Bleeding in
    diarhea • Eritema Rectum
    • Weight loss Nodusum
    • Loss of • Pyoderma
    Appetite Gangrenosum
    • Artritis
    • Eye
    involvement
    • Anemia

    9
    10
     Shows anemia
     Leucocytosis and increased of LED
     Hypokalemia
     Hypoalbuminemia
     Increased level of alkali phosphatase
     P-ANCA and ASCA antibody

    11
    12
     Crohn’s disease
     Tuberculose gastrointestinal

    13
    14
     Sulfasalazin containing moiety, 5-
    aminosalicylate  direct anti-inflammation
     without altering normal flora
     Corticosteroid is sulfasalazin not responding
     40-60mg/day prednisone, maintenance
    10-20mg/day
     azathioprine, cyclosporine, dan
    mercaptopurine  hematological supress
     Surgery

    15
     Anemia and factor coagulation disorder
     dental treatment consideration
     Apthous stomatitis  caused by
    malnutrition
     Pyoderma gangrenosum
     Pyostomatitis vegetans
     Hairy leukoplakia  caused by
    immunosupresive agent

    16
     Corticosteroid side effect 
    hyperglicaemia & hypertension  dental
    consideration
     CBC, Hb, Ht, liver function test  before
    drug administered

    17
     Prognosis mala  tachycardi, high fever,
    decrease intestinal peristaltic and
    hypoalbuminemia
     Can cause death  malnutrition,
    anemia in elderly
     Can develop pre cancerous lesion

    18
    19
     One of Inflammatory Bowel Disease
     Inflammation in GI tract, can affect from
    mouth to anus

    20
    Microorrganism Genetic Immunologic

    21
    22
    Subjective Extraoral Intraoral

    • Frequent • Anemia • Persistent


    abdominal • Fissura / mucosal
    pain nodula / swelling
    • Diarhea or fistula in • Cobblestone
    constipation intestine pattern in
    • Malaise • Malabsorption mucosa
    • Fever • Mucogingivitis
    • Loss of apetite • Linear
    • Loss of weight ulceration
    • Mucosal tags
    23
    24
    Pyostomatitis Vegetans in
    Crohn’s Disease

    Nodular Submucosa in bucal


    mucosa (Daley & Armstrong 2007)

    25
    Mucosal Tags in Crohn’s Disease (Kalmar 2000)

    26
     CBC
     Colonoscopy
     USG
     CT-Scan
     MRI

    27
     Ulcerative Colitis

    28
    • Mouthwash • Electrolyte
    • Antibiotics • If medication not • Low-fiber diet
    • Corticosteroid respond • Lactose-free diet
    • Aminosaliysilic acid • Cancer • Low-fat diet
    • Immunomodulator • Bleeding • Suplement
    • Obstruction / abcess

    Surgery
    Pharmacological Diet&Nutrition
    approach

    29
     Antiinflammation  Oral lichenoid drug
    reaction
     Superinfection Candida albicans
     Increased risk of caries
     Malabsorption  anemia  pallor,
    glositis, angular cheilitis
     Hematological consideration before
    dental treatment

    30
     Can total healed but can remission all
    the time
     Low fatality rate but in chronic disease
    can cause death

    31
    32

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