Acute Cholecystitis

Download as pptx, pdf, or txt
Download as pptx, pdf, or txt
You are on page 1of 10

Acute cholecystitis

Acute cholecystitis :- inflammation of gallbladder.


• It occurs in patient with pre-existing chronic cholecystitis.
Classification
1. Acute calculous cholecystitis
2. Acute acalculous cholecystitis
Mode of infection
• Haematogenous through hepatic artery (cystic artery)
• Portal vein
• Through bile after filtering in the liver via portal circulation.
Causative organisms :-
1. E.coli (most common)
2. Klebsiella , pseudomonas , proteus
3. Salmonella
4. Clostridium welchii
Pathogenesis :-
• Lumen contains infected bile/fluid.
• Mucosa shows ulceration & necrosis.
• Submucosa :- necrosis and infection.
• Area of necrosis and patchy gangrene.
• Gallbladder distended with oedematous
friable wall containing dilated vessels.
Clinical features :-
• Sudden onset of pain in right hypochondrium with tenderness ,
guarding/rigidity.
• Palpable soft gallbladder
• Fever , nausea, palpable tender mass in gallbladder region (25%).
• Boas’s sign :- area of hyperaesthesia between 9th and 11th rib posteriorly
extending 2.5cm lateral to spinous process of vertebrae on right side.
• Murphy’s sign :- Ask patient to take deep breath while exerting moderate
Pressure over right upper quadrant , patient catches breath as inflamed
gallbladder pushed down by diaphragm gets imposed against thumb.
Investigations :-
• USG – more than 4mm thickness of
gallbladder wall.
- presence of absence of gallstones.
• Plane X- ray abdomen
• Neutrophilia in blood examination. Calculous cholecystitis

• HIDA scan – non visualisation of


gallbladder is diagnostic.

Normal
HIDA scan
• CT scan for identifying
perforation ,impacted stones ,
gallbladder thickness and oedema.

• LFT – increase serum bilirubin often


signifies cholangitis / stones in CBD.
D/D :-
• Duodenal ulcer perforation
• Acute pancreatitis
• Acute pyelonephritis
• Acute appendicitis
• Lobar pneumonia ,MI .
• Ruptured ectopic pregnancy
Complications :-
1. Perforation (5-10%) lead to cholecystoduodenal,cholecystobiliary,
cholecystointestinal fistula ,mirrizi’s syndrome.
2. Peritonitis, pericholecystitic abscess.
3. Cholangitis, septicaemia
4. Empyema gallbladder, gangrenous bladder.
Treatment :-
• Advised hospitalisation.
• Initially conservative treatment (95%)
1. Nasogastric aspiration
2. Iv fluids
3. Analgesics and antispasmodics
4. Broad spectrum antibiotics (ceftazidime, ceftriaxone, cefotaxime+amikacin,
tobramycin+metronidazole).
5. Observation and follow-up for US scans.
Pt present within 72 hrs of attack Pt present after 72 hrs of attack

Conservative management followed by same Conservative management followed by interval


sitting laparoscopic cholecystectomy laparoscopic cholecystectomy after 4 -6 weeks
(due to vascular adhesions increase risk of
bleeding)
Indications for emergency cholecystectomy:-
• Empyema gallbladder
• Persisting symptoms or failure of medications.
• Emphysematous cholecystitis
• Perforation and peritonitis.
The gallbladder is opened and all stones and pus are
removed
Either foley’s or malecot’s catheter is placed in
gallbladder and exteriorised.
• After 3 weeks elective cholecystectomy is done.
THANK YOU

You might also like

pFad - Phonifier reborn

Pfad - The Proxy pFad of © 2024 Garber Painting. All rights reserved.

Note: This service is not intended for secure transactions such as banking, social media, email, or purchasing. Use at your own risk. We assume no liability whatsoever for broken pages.


Alternative Proxies:

Alternative Proxy

pFad Proxy

pFad v3 Proxy

pFad v4 Proxy