Lecture 14 Genetic Engineering

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Genetic engineering

Genetic engineering (also called genetic modification) is a process that


uses laboratory-based technologies to alter the DNA makeup of an
organism
Histroy
• Circa 8000 BCE: Humans use traditional modification methods like
selective breeding and cross-breeding to breed plants and animals
with more desirable traits.
• 1866: Gregor Mendel, an Austrian monk, breeds two different types
of peas and identifies the basic process of genetics.
• 1922: The first hybrid corn is produced and sold commercially.
• 1940: Plant breeders learn to use radiation or chemicals to randomly
change an organism’s DNA.
• 1953: Building on the discoveries of chemist Rosalind Franklin,
scientists James Watson and Francis Crick identify the structure of
DNA.
• 1973: Biochemists Herbert Boyer and Stanley Cohen develop genetic
engineering by inserting DNA from one bacteria into another.
• 1982: FDA approves the first consumer GMO product developed
through genetic engineering: human insulin to treat diabetes.
• 1986: The federal government establishes the Coordinated
Framework for the Regulation of Biotechnology. This policy describes
how the U.S. Food and Drug Administration (FDA), U.S. Environmental
Protection Agency (EPA), and U.S. Department of Agriculture (USDA)
work together to regulate the safety of GMOs.
• 1992: FDA policy states that foods from GMO plants must meet the
same requirements, including the same safety standards, as foods
derived from traditionally bred plants.
• 1994: The first GMO produce created through genetic engineering—a
GMO tomato—becomes available for sale after studies evaluated by
federal agencies proved it to be as safe as traditionally bred tomatoes.
• 1990s: The first wave of GMO produce created through genetic
engineering becomes available to consumers: summer squash, soybeans,
cotton, corn, papayas, tomatoes, potatoes, and canola. Not all are still
available for sale.

• 2003: The World Health Organization (WHO) and the Food and Agriculture
Organization (FAO) of the United Nations develop international guidelines
and standards to determine the safety of GMO foods.

• 2005: GMO alfalfa and sugar beets are available for sale in the United
States.

• 2015: FDA approves an application for the first genetic modification in an


animal for use as food, a genetically engineered salmon.
• 2016: Congress passes a law requiring labeling for some foods
produced through genetic engineering and uses the term
“bioengineered,” which will start to appear on some foods.

• Timeline of Genetic Modification in Agriculture


• 2017: GMO apples are available for sale in the U.S.

• 2019: FDA completes consultation on first food from a genome edited


plant.

• 2020: GMO pink pineapple is available to U.S. consumers.

• 2020: Application for GalSafe pig was approved

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