Viruses

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Viruses

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What are Viruses?
1.Viruses are acellular entities
2. DNA or RNA enclosed in a coat of
protein
3.All viruses have a nucleocapsid
composed of a nucleic acid surrounded
by a protein capsid that may be
icosahedral, helical, or complex in
structure.
4. May or may not have Envelope
5. They can reproduce only within living
cells (host)
6. obligately intracellular parasites
7. may be either single-stranded or
double-stranded DNA or RNA.
8. The nucleic acid strands can be linear,
closed circle, or able to assume either
shape. 2
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How viruses differ from
living cells?
Viruses differ from living cells in at least three
ways:
(1) their simple, acellular organization;
(2) the presence of either DNA or RNA, but not
both, in almost all virions (human
cytomegalovirus has a DNA genome and four
mRNAs);
(3) their inability to reproduce independent of
cells and do not carry out cell division as
procaryotes and eucaryotes do.

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Coronavirus

Size of coronavirus – 50nm to 140nm


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Size of coronavirus – 50nm to 140nm
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Are Viruses Living or
Non-living?

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Viruses are living because:
(i) They show growth and multiplication (only inside the host cell).
(ii) They have genetic material i.e. DNA/RNA.
(iii) They can direct protein synthesis (though they use host machinery for it).
(iv) They show mutation.
(v) They can be transmitted from the diseased host to the healthy ones or
posses
the ability to infect.
(vi) They react to heat, chemicals and radiation and also shows irritability, a
character of only living organisms.
(vii) They posses genetic continuity and have definite races/strains.
(viii) Similarity between nucleoproteins of viruses with the protein and
nucleic acid
of living organisms.

Viruses are non-living because:


(i) They can be crystallized (Stanley, 1935)
(ii) They behave as inert chemicals outside the host cell.
(iii) A cell wall or cell membrane of any type is absent in viruses.
(iv) They do not show functional autonomy
(v) They do not respire or excrete or they do not show any sign of
metabolism
except reproduction.
(vi) They lack any energy producing enzyme system. 10
Fun fact

Q1. Are antibiotics effective against virus???


Ans. No

Q2. Why doctor prescribe antibiotics to the


patient during viral fever?

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Type of viruses
Based on their host, viruses can be
classified into three types, namely,

1.animal viruses e.g. HIV,


2.plant viruses, and
3.bacteriophages (bacterial viruses).

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Replication of viruses
• The lytic cycle involves the
reproduction of viruses using a
host cell to manufacture more
viruses; the viruses then burst out
of the cell.

• The lysogenic cycle involves the


incorporation of the viral genome
into the host cell genome,
infecting it from within

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Bacteriophage virus

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Lytic cycle

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Thankyou

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