OR52I2

OR52I2
Identifiers
Aliases	OR52I2, OR11-12, OR52I1, olfactory receptor family 52 subfamily I member 2
External IDs	MGI: 3030390; HomoloGene: 17380; GeneCards: OR52I2; OMA:OR52I2 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11p15.4 Start 4,581,743 bp End 4,593,340 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 E3 Start 102,314,106 bp End 102,322,477 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle granulocyte Top expressed in epithelium body proper organ system sensory nervous system respiratory epithelium sensory organ structure with developmental contribution from neural crest nasal epithelium peripheral nervous system olfactory epithelium More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 143502 258749 Ensembl ENSG00000226288 ENSMUSG00000073969 UniProt Q8NH67 E9Q549 RefSeq (mRNA) NM_001005170 NM_001405760 NM_146754 RefSeq (protein) NP_001005170 NP_666965 Location (UCSC) Chr 11: 4.58 – 4.59 Mb Chr 7: 102.31 – 102.32 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 52I2 is a protein that in humans is encoded by the OR52I2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR52I2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.