Monosodium glutamate (MSG) is a sodium salt of glutamic acid, a naturally occurring non-essential... more Monosodium glutamate (MSG) is a sodium salt of glutamic acid, a naturally occurring non-essential amino acid. It is used as a food additive. It has the E number E621. The metabolic abnormalities and oxidative damage induced many diseases under the effect of monosodium glutamate (MSG) hazard, which is flavor enhancers used as an ingredient in various food products. The aim of this study is an assessment hazard of MSG by some biochemical and statistical analysis on serum rats. The rats were divided into 2 groups, each group contained 20 rats. The period of this study is four weeks. The first group is (control group) drinking water. The second group is (treated group) injected (4mg/kg B.W.) intraperitoneal (I.P.) of pure MSG from first week to third week and withdrawal in fourth week. After each week were anesthetized the rats with ether and blood was collected from the eye, for some biochemical analysis in heart, liver and kidney function tests. The present results revealed that chron...
Low concentrations of circulating 25-hydroxyvitamin D [25(OH)D] are common among adults, particul... more Low concentrations of circulating 25-hydroxyvitamin D [25(OH)D] are common among adults, particularly those diagnosed as overweight or obese. Female Saudi Arabian residents are at risk of developing vitamin D insufficiency related to cultural practices that reduce exposure to Ultraviolet B (UVB) radiation. During the past 10 years, there has been a dramatic increase in obesity and overweight over time in the Kingdom of Saudi Arabia (KSA) and the rates remain high. The objective of this study is to examine whether current weight and weight change since 18 years can alter vitamin D status among healthy Saudi women. We hypothesized that serum 25(OH) D is significantly higher in women who maintained stable weight over time than in those who gained weight. We conducted this study among 120 healthy women with a mean age 47.9 years; range (18–75) years, and a mean body mass index (BMI) of 29.7 kg/m 2 . Height, weight, serum 25(OH)D concentrations, and questionnaires about medical history, ...
The biosynthesis of metal nanoparticles is an expanding research area due to the potential applic... more The biosynthesis of metal nanoparticles is an expanding research area due to the potential applications for the ecofriendly development of novel technologies. Present study reported the antimicrobial properties of zinc oxide and manganese oxide nanoparticles were investigated using : Gram positive bacteria namely (Bacillus megaterium,
This study was designed to investigate the potential role of selenium on metabolic syndrome induc... more This study was designed to investigate the potential role of selenium on metabolic syndrome induced by fructose in rats. Thirty male Wister Albino rats weighing 185 to 225 g were used. The rats were randomly divided into 3 groups, 10 rats each. The first group received water only and set as a control (GI). The second group received 20% fructose in drinking water daily (GII). Third group (GIII) received fructose 20% and 0. 25 mg/0.5 ml distilled water/kg body weight per day selenium in drinking water. After 5 weeks of supplementation, rats were sacrificed; blood samples were obtained for different biochemical analysis including serum level of glucose; lipids profile were measured including total cholesterol, high density lipoprotein cholesterol (HDL-c), low density lipoprotein cholesterol (LDL-c) and triglyceride (TG). Liver function tests, alanine transaminase (ALT), aspartate transaminase (AST), albumin and total protein were carried out. Also, kidney function tests (creatinine, ur...
In the emerging issue of increased mult i-resistant properties in food borne pathogens, zinc o xi... more In the emerging issue of increased mult i-resistant properties in food borne pathogens, zinc o xide (Zn O) and nano-particle zinc o xide (nano-ZnO) are being used increasingly as antimicrobial agents. Thus, the min imu m inhibitory concentration (MIC) and minimu m bactericidal concentration (M BC) of nano -ZnO towards pathogens microbes Bacillus subtilus NRRL B-543, Bacillus megaterium ATCC 25848, Staphylococcus aureus; NRRL B-313, Sarcina lutea ATCC27853, Escherichia coli; NRRL B-210, Pseudomonas aeruginosa NRRL B23 27853, Klebsiella pneumoniae ATCC 27736, proteus vulgaris NRRL B-123, Candida albicans NRRL Y-477 and Aspergillus niger NRRL-3 were examined in this study.
The Journal of Infection in Developing Countries, 2015
This review documents the sporadic reporting of poultry Salmonella serovars in South Africa, Egyp... more This review documents the sporadic reporting of poultry Salmonella serovars in South Africa, Egypt, Indonesia, India, and Romania, five countries selected based on the importance of their distribution in different regions of the world and their cumulative significant population size of 1.6 billion. South Africa reported contamination of its poultry carcasses by S. Hadar, S. Blockley, S. Irumu, and S. Anatum. Results from Egypt showed that S. Enteritidis and S. Typhimurium were predominant in poultry along with other non-typhoid strains, namely S. Infantis, S. Kentucky, S. Tsevie, S. Chiredzi, and S. Heidelberg. In Indonesia, the isolation of Salmonella Typhi was the main focus, while other serovars included S. Kentucky, S. Typhimurium, and S. Paratyhi C. In India, S. Bareilly was predominant compared to S. Enteritidis, S. Typhimurium, S. Paratyphi B, S. Cerro, S. Mbandaka, S. Molade, S. Kottbus, and S. Gallinarum. Romania reported two Salmonella serovars in poultry that affect humans, namely S. Enteritidis and S. Typhimurium, and other non-typhoid strains including S. Infantis, S. Derby, S. Colindale, S. Rissen, S. Ruzizi, S. Virchow, S. Brandenburg, S. Bredeney, S. Muenchen, S. Kortrijk, and S. Calabar. The results showed the spread of different serovars of Salmonella in those five developing countries, which is alarming and emphasizes the urgent need for the World Health Organization Global Foodborne Infections Network (WHO-GFN) to expand its activities to include more strategic participation and partnership with most developing countries in order to protect poultry and humans from the serious health impact of salmonellosis.
The present work aimed to evaluate the effect of each of green tea (GT) and garlic (Ga) aqueous e... more The present work aimed to evaluate the effect of each of green tea (GT) and garlic (Ga) aqueous extract and their combination on pesticide Duracine induced changes in plasma levels of some indices of oxidative stress; and in protein electrophoretic patterns, in albino rats. Study Design: Forty rats were divided into 8 groups 5rats each and treated orally for 14 days as follows: G1 (control);-G 2 (200mg GT per animal);-G 3 (1ml of 50% of garlic):-G4 (200mg green tea per animal and 1ml of 50% of garlic); G 5 20mg /Kg bwt [equivelant 1/14 LD50 of Duracine] ,G6 (green tea and Duracine):-G7 (garlic and Duracine):-G8 (green tea, garlic and Duracine). Plasma activities of acetylcholinesterase (AChE), glutathione-Stransferase (GST) and glutathione reductase (GR) activities and levels of malondialdehyde (MDA) and total reduced glutathione (GSH) were analyzed using standard methods. Results: Duracine intoxication induced significant decrease in plasma AChE, GST and
_______________________________________________________________________ Abstract High fructose di... more _______________________________________________________________________ Abstract High fructose diet fed rat model is known to develop the insulin-resistant syndrome with a very similar metabolic profile to the human X syndrome. The aim of the current study was to investigate the antioxidant and protective effect of selenium on insulin sensitivity induced by high fructose in rats. Forty male Wister rats were randomly divided into four groups (n=10): Healthy control rats, high fructose-fed rats, selenium treated rats fed high fructose and selenium fed control rats. Insulin resistance was induced in the second and third groups by administration of high-fructose diet for a period of five weeks. Fasting blood glucose (FBG) and insulin levels were higher in fructose-fed rats while oxidative stress parameters were lower than in control rats (p<0.05). Selenium administration can significantly improved the oxidative stress parameters and FBS levels in fructose fed-selenium treated rats co...
Monosodium glutamate (MSG) is a sodium salt of glutamic acid, a naturally occurring non-essential... more Monosodium glutamate (MSG) is a sodium salt of glutamic acid, a naturally occurring non-essential amino acid. It is used as a food additive. It has the E number E621. The metabolic abnormalities and oxidative damage induced many diseases under the effect of monosodium glutamate (MSG) hazard, which is flavor enhancers used as an ingredient in various food products. The aim of this study is an assessment hazard of MSG by some biochemical and statistical analysis on serum rats. The rats were divided into 2 groups, each group contained 20 rats. The period of this study is four weeks. The first group is (control group) drinking water. The second group is (treated group) injected (4mg/kg B.W.) intraperitoneal (I.P.) of pure MSG from first week to third week and withdrawal in fourth week. After each week were anesthetized the rats with ether and blood was collected from the eye, for some biochemical analysis in heart, liver and kidney function tests. The present results revealed that chron...
Low concentrations of circulating 25-hydroxyvitamin D [25(OH)D] are common among adults, particul... more Low concentrations of circulating 25-hydroxyvitamin D [25(OH)D] are common among adults, particularly those diagnosed as overweight or obese. Female Saudi Arabian residents are at risk of developing vitamin D insufficiency related to cultural practices that reduce exposure to Ultraviolet B (UVB) radiation. During the past 10 years, there has been a dramatic increase in obesity and overweight over time in the Kingdom of Saudi Arabia (KSA) and the rates remain high. The objective of this study is to examine whether current weight and weight change since 18 years can alter vitamin D status among healthy Saudi women. We hypothesized that serum 25(OH) D is significantly higher in women who maintained stable weight over time than in those who gained weight. We conducted this study among 120 healthy women with a mean age 47.9 years; range (18–75) years, and a mean body mass index (BMI) of 29.7 kg/m 2 . Height, weight, serum 25(OH)D concentrations, and questionnaires about medical history, ...
The biosynthesis of metal nanoparticles is an expanding research area due to the potential applic... more The biosynthesis of metal nanoparticles is an expanding research area due to the potential applications for the ecofriendly development of novel technologies. Present study reported the antimicrobial properties of zinc oxide and manganese oxide nanoparticles were investigated using : Gram positive bacteria namely (Bacillus megaterium,
This study was designed to investigate the potential role of selenium on metabolic syndrome induc... more This study was designed to investigate the potential role of selenium on metabolic syndrome induced by fructose in rats. Thirty male Wister Albino rats weighing 185 to 225 g were used. The rats were randomly divided into 3 groups, 10 rats each. The first group received water only and set as a control (GI). The second group received 20% fructose in drinking water daily (GII). Third group (GIII) received fructose 20% and 0. 25 mg/0.5 ml distilled water/kg body weight per day selenium in drinking water. After 5 weeks of supplementation, rats were sacrificed; blood samples were obtained for different biochemical analysis including serum level of glucose; lipids profile were measured including total cholesterol, high density lipoprotein cholesterol (HDL-c), low density lipoprotein cholesterol (LDL-c) and triglyceride (TG). Liver function tests, alanine transaminase (ALT), aspartate transaminase (AST), albumin and total protein were carried out. Also, kidney function tests (creatinine, ur...
In the emerging issue of increased mult i-resistant properties in food borne pathogens, zinc o xi... more In the emerging issue of increased mult i-resistant properties in food borne pathogens, zinc o xide (Zn O) and nano-particle zinc o xide (nano-ZnO) are being used increasingly as antimicrobial agents. Thus, the min imu m inhibitory concentration (MIC) and minimu m bactericidal concentration (M BC) of nano -ZnO towards pathogens microbes Bacillus subtilus NRRL B-543, Bacillus megaterium ATCC 25848, Staphylococcus aureus; NRRL B-313, Sarcina lutea ATCC27853, Escherichia coli; NRRL B-210, Pseudomonas aeruginosa NRRL B23 27853, Klebsiella pneumoniae ATCC 27736, proteus vulgaris NRRL B-123, Candida albicans NRRL Y-477 and Aspergillus niger NRRL-3 were examined in this study.
The Journal of Infection in Developing Countries, 2015
This review documents the sporadic reporting of poultry Salmonella serovars in South Africa, Egyp... more This review documents the sporadic reporting of poultry Salmonella serovars in South Africa, Egypt, Indonesia, India, and Romania, five countries selected based on the importance of their distribution in different regions of the world and their cumulative significant population size of 1.6 billion. South Africa reported contamination of its poultry carcasses by S. Hadar, S. Blockley, S. Irumu, and S. Anatum. Results from Egypt showed that S. Enteritidis and S. Typhimurium were predominant in poultry along with other non-typhoid strains, namely S. Infantis, S. Kentucky, S. Tsevie, S. Chiredzi, and S. Heidelberg. In Indonesia, the isolation of Salmonella Typhi was the main focus, while other serovars included S. Kentucky, S. Typhimurium, and S. Paratyhi C. In India, S. Bareilly was predominant compared to S. Enteritidis, S. Typhimurium, S. Paratyphi B, S. Cerro, S. Mbandaka, S. Molade, S. Kottbus, and S. Gallinarum. Romania reported two Salmonella serovars in poultry that affect humans, namely S. Enteritidis and S. Typhimurium, and other non-typhoid strains including S. Infantis, S. Derby, S. Colindale, S. Rissen, S. Ruzizi, S. Virchow, S. Brandenburg, S. Bredeney, S. Muenchen, S. Kortrijk, and S. Calabar. The results showed the spread of different serovars of Salmonella in those five developing countries, which is alarming and emphasizes the urgent need for the World Health Organization Global Foodborne Infections Network (WHO-GFN) to expand its activities to include more strategic participation and partnership with most developing countries in order to protect poultry and humans from the serious health impact of salmonellosis.
The present work aimed to evaluate the effect of each of green tea (GT) and garlic (Ga) aqueous e... more The present work aimed to evaluate the effect of each of green tea (GT) and garlic (Ga) aqueous extract and their combination on pesticide Duracine induced changes in plasma levels of some indices of oxidative stress; and in protein electrophoretic patterns, in albino rats. Study Design: Forty rats were divided into 8 groups 5rats each and treated orally for 14 days as follows: G1 (control);-G 2 (200mg GT per animal);-G 3 (1ml of 50% of garlic):-G4 (200mg green tea per animal and 1ml of 50% of garlic); G 5 20mg /Kg bwt [equivelant 1/14 LD50 of Duracine] ,G6 (green tea and Duracine):-G7 (garlic and Duracine):-G8 (green tea, garlic and Duracine). Plasma activities of acetylcholinesterase (AChE), glutathione-Stransferase (GST) and glutathione reductase (GR) activities and levels of malondialdehyde (MDA) and total reduced glutathione (GSH) were analyzed using standard methods. Results: Duracine intoxication induced significant decrease in plasma AChE, GST and
_______________________________________________________________________ Abstract High fructose di... more _______________________________________________________________________ Abstract High fructose diet fed rat model is known to develop the insulin-resistant syndrome with a very similar metabolic profile to the human X syndrome. The aim of the current study was to investigate the antioxidant and protective effect of selenium on insulin sensitivity induced by high fructose in rats. Forty male Wister rats were randomly divided into four groups (n=10): Healthy control rats, high fructose-fed rats, selenium treated rats fed high fructose and selenium fed control rats. Insulin resistance was induced in the second and third groups by administration of high-fructose diet for a period of five weeks. Fasting blood glucose (FBG) and insulin levels were higher in fructose-fed rats while oxidative stress parameters were lower than in control rats (p<0.05). Selenium administration can significantly improved the oxidative stress parameters and FBS levels in fructose fed-selenium treated rats co...
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