Receptor vazoaktivnog intestinalnog peptida

Vazoaktivni intestinalni peptidni receptor 1
Identifikatori
Simbol	VIPR1
Alt. simboli	RDC1, HVR1, VAPC1
Entrez	7433
HUGO	12694
OMIM	192321
RefSeq	NM_004624
UniProt	P32241
Ostali podaci
Lokus	Hromozom 3 p22

Vazoaktivni intestinalni peptidni receptor 2
Identifikatori
Simbol	VIPR2
Alt. simboli	VPAC2
Entrez	7434
HUGO	12695
OMIM	601970
RefSeq	NM_003382
UniProt	P41587
Ostali podaci
Lokus	Hromozom 7 q36.3

Hipofizni adenilat ciklazno aktivirajući polipeptidni receptor tip I
Identifikatori
Simbol	ADCYAP1R1
Alt. simboli	PACAPR
Entrez	117
HUGO	242
OMIM	102981
RefSeq	NM_001118
UniProt	P41586
Ostali podaci
Lokus	Hromozom 7 p14

Poznata su dva receptora za vazoaktivni intestinalni peptid (VIP): VPAC₁ i VPAC₂.^[1]^[2] Za ove receptore se vezuje VIP i u izvesnoj meri hipofizni adenilat ciklazno aktivirajući peptid (PACAP). Oba receptora su članovi 7 transmembranske familije G protein spregnutih receptora.

Reference

^ Laburthe M, Couvineau A, Marie JC (2002). „VPAC receptors for VIP and PACAP”. Recept. Channels. 8 (3-4): 137—53. PMID 12529932. doi:10.1080/10606820213680.
^ Laburthe M, Couvineau A (2002). „Molecular pharmacology and structure of VPAC Receptors for VIP and PACAP”. Regul. Pept. 108 (2-3): 165—73. PMID 12220741. doi:10.1016/S0167-0115(02)00099-X.

„VIP and PACAP Receptors”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Архивирано из оригинала 03. 03. 2016. г.
Receptors,+Vasoactive+Intestinal+Peptide на US National Library of Medicine Medical Subject Headings (MeSH)

Adrenergički	α1 (A, B, D) • α2 (A, B, C) • β1 • β2 • β3
Purinski	Adenozinski (A1, A2A, A2B, A3) • P2Y (1, 2, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14)
Serotoninski	(svi osim 5-HT3) 5-HT1 (A, B, D, E, F) • 5-HT2 (A, B, C) • 5-HT (4, 5A, 6, 7)
Drugi	Acetilholin (M1, M2, M3, M4, M5) • Dopamin (D1, D2, D3, D4, D5) • Histamin (H1, H2, H3, H4) • Melatonin (1A, 1B, 1C) • TAAR (1, 2, 3, 5, 6, 8, 9)

Metaboliti i
signalni molekuli

Eikozanoidni	CysLT (1, 2) • LTB4 (1, 2) • FPRL1 • OXE • Prostaglandin (DP (1, 2), EP (1, 2, 3, 4), FP) • Prostaciklin • Tromboksan
Drugi	Žučna kiselina • Kanabinoidni (CB1, CB2, GPR (18, 55, 119)) • EBI2 • Estrogen • Slobodna masna kiselina (1, 2, 3, 4) • Laktat • Lizofosfatidna kiselina (1, 2, 3, 4, 5, 6) • Lizofosfolipid (1, 2, 3, 4, 5, 6, 7, 8) • Niacin (1, 2) • Oksoglutarat • PAF • Sfingozin-1-fosfat (1, 2, 3, 4, 5) • Sukcinat

Peptid

B/W (1, 2) • FF (1, 2) • S • Y (1, 2, 4, 5) • Neuromedin (B, U (1, 2)) • Neurotenzin (1, 2)

Drugi

Razno

Orfan	GPR (1, 3, 4, 6, 12, 15, 17, 18, 19, 20, 21, 22, 23, 25, 26, 27, 31, 32, 33, 34, 35, 37, 39, 42, 44, 45, 50, 52, 55, 61, 62, 63, 65, 68, 75, 77, 78, 81, 82, 83, 84, 85, 87, 88, 92, 101, 103, 109A, 109B, 119, 120, 132, 135, 137B, 139, 141, 142, 146, 148, 149, 150, 151, 152, 153, 160, 161, 162, 171, 173, 174, 176, 177, 182, 183)
Drugi	Adrenomedulin • Mirisni • Opsin (3, 4, 5, 1LW, 1MW, 1SW, RGR, RRH) • Proteazom-aktivirani (1, 2, 3, 4) • SREB (1, 2, 3)

Orfan	GPR (56, 64, 97, 98, 110, 111, 112, 113, 114, 115, 116, 123, 124, 125, 126, 128, 133, 143, 144, 155, 157)
Drugi	Moždano specifični angiogenezni inhibitor (1, 2, 3) • Kadherin (1, 2, 3) • Kalcitonin • CALCRL • CD97 • Kortikotropin-oslobađajući hormon (1, 2) • EMR (1, 2, 3) • Glukagon (GR, GIPR, GLP1R, GLP2R) • Hormon rasta • PACAPR1 • GPR • Latrofilin (1, 2, 3, ELTD1) • Metuzalemski protein • Paratiroidni hormon (1, 2) • Sekretin • Vazoaktivni intestinalni peptid (1, 2)

Ukus	TAS1R (1, 2, 3) • TAS2R (1, 3, 4, 5, 8, 9, 10, 12, 13, 14, 16, 19, 20, 30, 31, 38, 39, 40, 41, 42, 43, 45, 46, 50)
Drugi	Kalcijum-detektujući receptor • GABA B (1, 2) • Glutamatni receptor (Metabotropni glutamat (1, 2, 3, 4, 5, 6, 7, 8)) • GPRC6A • GPR (156, 158, 179) • RAIG (1, 2, 3, 4) • VNR (1, 2, 3, 5)

Uvojiti	Frizzled (1, 2, 3, 4, 5, 6, 7, 8, 9, 10)
Zaglađeni	Zaglađeni

Hipotalamusni	CRH – FSH – LHRH – TRH – Somatostatin
Hipofizni	Vazopresin (1A, 1B, 2) – Oksitocin – LHCG – Tip I citokinski receptor (GH, Prolaktin) – TSH
Drugi	Atrijalni natriuretski faktor (NPR1, NPR2, NPR3) – Kalcitonin – Holecistokinin (A, B) – VIP