Wearable Biosensor Report

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DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT

DEPT. OF ELEC. KURUKSHETRA UNIVERSITY




ABSTRACT

Recent advancements in miniature devices have fostered a dramatic growth of interest of
wearable technology. Wearable Bio-Sensors (WBS) will permit continuous cardiovascular (CV)
monitoring in a number of novel settings. WBS could play an important role in the wireless
surveillance of people during hazardous operations (military, firefighting, etc) or such sensors
could be dispensed during a mass civilian casualty occurrence. They typically rely on wireless,
miniature sensors enclosed in ring or a shirt. They take advantage of handheld units to temporarily
store physiological data and then periodically upload that data to a database server via wireless
LAN or a cradle that allow Internet connection and used for clinical diagnosis.























DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


CONTENTS


1. INTRODUCTION
2. DEVELOPMENT OF WEARABLE BIOSENSOR
2.1. RING SENSOR
2.1.1 BASIC PRICIPLE
2.1.2 WORKING
2.1.3 BLOCK DIAGRAM
2.1.4 APPLICATIONS
2.1.5 ADVANTAGES AND DISADVANTAGES
2.2. SMART SHIRT (WEARABLE MOTHERBOARD)
2.2.1 REQUIREMENTS
2.2.2 ARCHITECTURE
2.2.3 APPLICATIONS
2.2.4. IMPACTS
2.2.5. ADVANTAGES AND DISADVANTAGES
3. UPCOMING APPLICATIONS OF WEARABLE BIOSENSORS
4. FUTURE TRENDS
5. CONCLUSION
6. REFERENCES


DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


1. INTRODUCTION

Wearable sensors and systems have evolved to the point that they can be considered ready for
clinical application. The use of wearable monitoring devices that allow continuous or intermittent
monitoring of physiological signals is critical for the advancement of both the diagnosis as well as
treatment of diseases.

Wearable systems are totally non-obtrusive devices that allow physicians to overcome the
limitations of ambulatory technology and provide a response to the need for monitoring individuals
over weeks or months. They typically rely on wireless miniature sensors enclosed in patches or
bandages or in items that can be worn, such as ring or shirt. The data sets recorded using these
systems are then processed to detect events predictive of possible worsening of the patients
clinical situations or they are explored to access the impact of clinical interventions.
















DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


2.DEVELOPMENT OF WEARABLE BIOSENSOR

2.1. RING SENSOR
It is a pulse oximetry sensor that allows one to continuously monitor heart rate and oxygen
saturation in a totally unobtrusive way. The device is shaped like a ring and thus it can be worn for
long periods of time without any discomfort to the subject. The ring sensor is equipped with a low
power transceiver that accomplishes bi-directional communication with a base station, and to
upload date at any point in time.

2.1.1 BASIC PRINCIPLE OF RING SENSOR

Each time the heart muscle contracts, blood is ejected from the ventricles and a pulse of
pressure is transmitted through the circulatory system.
This pressure pulse when traveling through the vessels, causes vessel wall displacement which is
measurable at various points. In order to detect pulsatile blood volume changes by photoelectric
method, photo conductors are used. Normally photo resistors are used, for amplification purpose
photo transistors are used.[3]
Light is emitted by LED and transmitted through the artery and the resistance of photo
resistor is determined by the amount of light reaching it. with each contraction of heart, blood is
forced to the extremities and the amount of blood in the finger increases.it alters the optical density
with the result that the light transmission through the finger reduces and the resistance of the photo
resistor increases accordingly. The photo resistor is connected as a part of voltage divider circuit and
produces a voltage that varies with the amount of blood in the finger. This voltage that closely
follows the pressure pulse

.
2.1.2WORKING
The LEDs and PD are placed on the flanks of the finger either reflective or transmittal type
can be used. For avoiding motion disturbances quite stable transmittal method is used. Transmittal
type has a powerful LED for transmitting light across the finger. This power consumption problem
can be solved with a light modulation technique using high-speed devices. Instead of lighting the
skiing continuously, the LED is turned ON only for a short time, say 10-100 ns, and the signal is
sampled within this period, high frequency, low duty rate modulation is used for preventing skin-
burning problem.

DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY

The motion of the finger can be measure with an optical sensor. This motion detector can be
used not only for monitoring the presence of motion but also for cancelling the noise. By using PD-
B as a noise reference, a noise cancellation filter can be built to eliminate the noise of PD-A that
completes with the noise references used. And adaptive noise cancellation method is used.








Fig.1.Noise Cancellation Mechanism

The noise-canceling filter combines two sensor signals; one is the main signal captured by
PD-A and the other is the noise reference obtained by PD-B. The main signal mostly consists of
the truce pulsate signal, but it does contain some noise. If we know the proportion of noise
contained in the main signal, we can sensate the contained in the main signal, we can generate the
noise of the same magnitude by attending the noise reference signal and then subtract the noise
from the main signal to recover the true pulsatile signal.

fig.2.prototype of ring sensor

Signal
Source
Main
Signal
Noise
Source
Noise
Reference
Adaptive
Filter
+
-
Photo detector A
Photo detector B
DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY

The ring has a microcomputer performing all the device controls and low level signal
processing including LED modulation, data acquisition, filtering, and bi-directional RF
communication. The acquired waveforms sampled at 100Hz are transmitted to a cellular phone
carried by the patient through an RF link of 105Kbps at a carrier frequency of 915 MHz. The
cellular phone accesses a website for data storage and clinical diagnosis.

2.1.3. BLOCK DIAGRAM OF RING SENSOR

fig.3
Power Source

Power for light source, photo detector, RF transmitter and analog and digital processing
units provided by a tiny cell battery used for wrist watches. Lifetime is 2 or 3 weeks.

Light Source

Light source for the ring sensor is the LED, approximately wavelength of 660 nm.



DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


Photo Detector

Photo detector is normally photodiode or phototransistor used for detecting the signal from
the LED.

RF Transmitter
It is used for transmitting the measured signals. Its carrier frequency is 915MHz.

LED Modulation

Power consumption problem can be solved with a lighting modulation technique. Instead of
lighting the skin continually the LEDis turned on only for a short time, say 100-1000ns and the
signal is sampled within the period. High frequency low duty cycle modulation implemented
minimizes LED power consumption.[4]

Data Acquisition

It is used to collect the data from sensor and data are sampled and recorded.

Filtering

The signal from the PD-B as a noise reference a noise cancellation filter can be built to
eliminate the noise of PD-A that correlates with the noise reference signal. For noise cancellation
we use the adaptive noise filter.









DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY



2.1.4APPLICATIONS OF THE RING SENSOR

CATRASTOPHE DETECTION
Wireless supervision of people during hazardous operations
Eg: military, fire fighting
.In an overcrowded emergency department
CHRONIC MEDICAL CONDITION
in cardiovascular disease for monitoring the hyper tension
chronic surveillance of abnormal heart failure
2.1.5 ADVANTAGES
continuous monitoring
detection of transient phenomena
promote further diagnostic and therapeutic measures
easy to use
reducing hospitalization fee
DISADVANTAGES
initial cost is high
limited number of physiological parameters are to be monitored
2.2.SMART SHIRT (WEARABLE MOTHERBOARD)
Smart shirt developed at Georgia tech which represents the first attempt at relying an
unobtrusive, mobile and easy to use vital signs monitoring system; presents the key applications of
the smart shirt technology along with its impact on the practice of medicine; and covers key
opportunities to create the next generation of truly adaptive and responsive medical systems.
Research on the design and development of a smart shirt fort a combat casualty care has led
to the realization of the worlds first wearable motherboard or an intelligent garment for the 21
st

century. The Georgia tech wearable motherboard (GTWM) uses optical fibers to detect bullet
wounds and special sensors and interconnects to monitor the body vital signs during combat
conditions. This GTWM (smart shirt) provides an extremely versatile framework for the
incorporation of sensing, monitoring and information processing devices. The principal advantage
of smart shirt is that it provides for the first time a very systematic way of monitoring the vital signs
of humans in an unobtrusive manner.
DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


2.2.1.REQUIREMENTS OF SMART SHIRT

Casualties are associated with combat and sometimes are inevitable. Since medical resources
are limited in a combat scenario, there is critical need to make optimum use of the available
resources to minimize the loss of human life, which has value that is priceless. In a significant
departure from the past, the loss of even a single soldier in a war can alter the nations engagement
strategy making it all the important to save lives.[2]

Similarly on the civilian side, the population is aging and the cost of the health care delivery
is expected to increase at a rate faster than it is today. With the decreasing number of doctors in
rural areas, the doctor/patient ratio is in certain instances reaching unacceptable levels for ensuring
a basic sense of security when they leave the hospital because they feel cutoff from the
continuous watch and care they received in the hospital. This degree of uncertainty can greatly
influence their postoperative recovery. Therefore there is a need to continuously monitor such
patients and give them the added peace of mind so that the positive psychological impact will speed
up the recovery process.

Mentally ill patients need to be monitored on a regular basis to gain a better understanding of
the relationship between their vital signs and their behavioral patterns so that their treatments can
be suitably modified. Such medical monitoring of individuals is critical for the successful practice
of telemedicine that is becoming economically viable in the context of advancements in computing
and telecommunication, likewise continuous monitoring of astronauts in space, of athletes during
practice sessions and in competition, of law enforcement personnel and combat soldiers in the line
of duty are all extremely important.









DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


2.2.2ARCHITECTURE

The GTWM was woven into a single piece garment (an undershirt) on a weaving machine
to fit a 38-40 chest. The plastic optical fiber (POF) is spirally integrated into the structure during
the fabric production process without any discontinuities at the armhole or the segms using a novel
modification in the weaving process.



fig.4.requirements of smart shirts
An interconnection technology was developed to transmit information from (and to) sensors
mounted at any location on the body thus creating a flexible bus structure. T-connectors similar
to button clips used in clothing are attached to the fibers that serve as a data bus to carry the
information from the sensors (eg: ECG sensors) on the body.


DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


The sensors will plug into these connectors and at the other end similar T-connector will be
used to transmit their information for monitoring equipment or DARPS (Defense Advanced
Research Projects Agency) personnel status monitor .By making the sensors detachable from the
garments, the versatility I\of the Georgia Tech Smart Shirt has been significantly enhanced. Since
shapes and sizes of humans will be different, sensors can be positioned on the right locations for all
users and without any constraints being imposed by the smart shirt can be truly customized.
Moreover the smart shirt can be laundered without any damage to the sensors themselves.

The interconnection technology has been used to integrate sensors for monitoring the
following vital signs: temperature, heart rate and respiration rate .In addition a microphone has been
attached to transmit the weavers voice data to monitoring locations. Other sensors can be easily
integrated into the structure. The flexible data bus integrated into the stricture transmits the
information from the suite of the sensors to the multifunction processor known as the Smart shirt
controller. This controller in turn processes the signals and transmit them wirelessly to desired
locations (eg: doctors office, hospital, battlefield). The bus also serves to transmit information to
the sensors (and hence the weaver) from the external sources, thus making the smart shirt a
valuable information infrastructure.


fig.5.Architecture of smartshirt

A combat soldier sensor to his body, pulls the smart shirt on, and attaches the sensors to the
smart shirt. The smart shirt functions like a mo0therboard, with plastic optical fibers and other
special fibers woven throughout the actual fabric of the shirt. To pinpoint the exact location of a
DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY

bullet penetration, a signal is sent from one end of the plastic optical fiber to a receiver at the
other end. The emitter and the receiver are connected to a Personal Status Monitor (psm) worn at
the hip level by the soldier. If the light from the emitter does not reach the receiver inside the PSM,
it signifies that the smart shirt has been penetrated (i.e.; the soldier has been shot). The signal
bounces back to the PSM forum the point of penetration, helping the medical personnel pinpoint
the exact location the solider wounds.[6]

The soldiers vital signs heart rate, temperature, respiration rate etc. are monitored in two
ways: through the sensors integrated into the T-shirt: and through the sensors on the soldiers body,
both of which are connected to the PSM. Information on the soldiers wound and the condition is
immediately transmitted electronically from the PSM to a medical triage unit somewhere near the
battlefield. The triage unit them dispatches the approximate medical personnel to the scene .The
Georgia tech smart shirt can help a physician determine the extent of a soldiers injuries based on
the strength of his heart beat and respiratory rate. This information is vital for accessing who needs
assistance first during the so-called Golden Hour in which there are numerous casualties.

2.2.3. APPLICATIONS OF SMART SHIRT

Combat casualty care.
Medical monitoring.
Sports/ Performance monitoring.
Space experiments.
Mission critical/ hazardous application.
Fire- fighting.
Wearable mobile information infrastructure.

The vital signs information gathered by the various sensors on the body travels through the
smart shirt controller for processing, from these, the computed vital signals are wirelessly
transmitted using the communication information infrastructure in place in that application (e.g.:
the firefighters, communication systems, battlefield communication infrastructure, the hospital
network) to the monitoring station. There, the back-end Data display and Management system
with a built in knowledge based decision support system- in reverse these vital signs ask in real-
time and provide the right response to the situation.

DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY

Table 1 summarizes the broad range of application of the smart shirt technology. The table
also shows the application type and the target population that can utilize the technology.






DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


Fig.5.Applications of smart shirt

2.2.4.IMPACT OF THE SMART SHIRT

The smart shirt will have significant impact on the practice of medium since it fulfills the
critical need for a technology that can enhance the quality of life while reducing the health care cost
across the continuum of life that is from newborns to senior citizens, and across the continuum of
medical care that is from hospitals and everywhere in between.
The smart shirt can contribute to reduction in health care cost while enhancing the quality of
life. For instance, patients could wear the smart shirt at home and be monitored by a monitoring
DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


station, thereby avoiding hospital stay cost and reducing the overall cost of healthcare. At also same
home, a home setting can contribute to faster recovery. For example, if the patient recovering at
home from heart surgery is wearing the smart shirt, the ECG can be transmitted wirelessly (through
mobile phone, internet etc) to the hospital on a regular basis. This monitoring will help the patient
feel more secure and will facilitate the recuperation while simultaneously reducing the cost time
associated with recovery. Moreover, in the event of an emergency, the doctor can be notified
instantaneously. Using the online medical records (available over the web) the physician can
administrate the right investment at the right time at the right cost and indeed save a life, thereby
realizing the full potential of the smart shirt technology.

Furthermore, persons who have known disorders can wear the smart shirt and be under
constant monitoring of the physical conditions by medical personnel. Yet another potential impact
of the smart shirt technology is the eventual disappearance of geographical/physical boundaries as
barriers for individual seeking the best in healthcare worldwide.

The smart shirt technology has the means to provide unobstructed monitoring for individuals
and can thereby play a critical role disease management for the large numbers of individuals at risk
for high blood pressure, heart disease, diabetes, chronic bronchitis, and depression by enabling
early systematic intervention.

2.2.5.ADVANTAGES OF THE SMART SHIRT

Continuous monitoring
Right Treatment at the right time at the right cost
Easy to wear and takeoff.
Reducing the health care cost

DISADVANTAGES OF THE SMART SHIRT

Initial cost is high
Battery life is less

DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


3. UPCOMING APPLICATIONS OF WEARABLE BIOSENSORS

WEARABLE SENSOR FOR PREVENTING ROAD ACCIDENTS

Road safety is the most important issue worldwide as it has led to the loss of precious
lives. To solve this problem, various sensing techniques has been developed like measuring of
vehicles characteristics (steering wheel etc.), environmental conditions (fog, dark etc.), drivers
behavioral pattern. Wearable computers has played a major role in continuous monitoring of the
measures for avoiding road accidents and these computers also helps in providing the information
to the recovery agencies whenever a road accident takes place. The major cause for the road
accidents is the consumption of alcohol by the driver, long driving hours, lack of sleep, drowsiness
etc. However, Wearable devices are not the final solution for avoiding road accidents but other
measures such as facial expression recognition, speech recognition for estimating the drivers
emotional state.

SMART CLOTHING
Smart clothing has proved to be a new form of social interaction through enhanced
ability for self-actualization and self-expressions and self-determination. Some examples include:

Internet connected shoes-

These are the shoes which allows the individual to run with a jogging partner at distant places while
remain connected to the internet. Fig.7 shows the internet connected shoes that consists of sensors
and measures the impact of parts of shoe with the ground. Such technology enhances the ability of
self-expression.










Fig.7 Internet connected shoe

Wear Cam
This is the device for effortless display, processing and transmission of visual imagery. The
wearcam is invented considering the following entities:
DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


Cameras are attached to the body in such a way that both the hands remain free

Ways of recording, processing and transmitting images from the cameras

A display that has the capability of presenting the stream of images from the camera

BIOSENSORS FOR HYPERTENSION

Hypertension is a disease related to genetic and environmental origins that causes
the direct changes on the vasculature that includes smooth muscle cell proliferation. This disease
is a multi-factorial and requires long life treatment. In this case, various biosensors are used in
the body that automatically controls the blood pressure as high blood pressure leads to heart
attacks. Baroreceptors are the parameters that acts as a wearable biosensor for continuous
monitoring of blood pressure as it can change every minute.











Fig. 8 Schematic representation of the complex function and multiple interactions among arterial
baroreceptors, cardiovascular system and neural pathways.

The function of baroreceptor includes the regulation of blood pressure through various techniques
like modification of the sympathetic output, loss of afferent baroceptor stimulus, baroreceptor
resetting etc. due to ageing, diet, atherosclerosis changes the vascular physiology that further
changes the sensitivity of baroreceptor which in turn impacts the blood pressure and heart rate
control



DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


FOR WOUND HEALING MONITORING

Wearable biosensors are in demand as they are developed as immune sensors for
continuous monitoring of the wound healing technique which is based on pH change and on the
concentration of inflammatory proteins like CRP (C-reactive protein). In this sensing technique,
the hydrogels are used that swells whenever there is a change in the surroundings. The
detection principle is based on an optical signal, probing refractive index change. The sensor acts
as a patch that is an optical sensing system and includes a white LED and a spectrometer for
detection

WEARABLE SENSORS TO IMPROVE BREATHING

Breathing is a naturally occurring phenomenon. By deep breathing in a slow and regular
manner, our heartbeat becomes smooth and regular, the blood pressure becomes normal,
which drops the stress hormones and the muscles relaxes. Here, the breathing monitoring
system shown in fig.11, is being developed to improve the breathing techniques, by monitoring
thoracic and abdominal movements






Fig.11 Breath monitoring system

Wearable sensor: detects the movements of the body due to breathing
Microcontroller: It is basically the Arduino microcontroller which is an open source
electronics prototyping platform







DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


PHYSPUT

It is the physiological input which allows the user to emulate the standard computer input
into nonstandard input. Eg. Mouse movements and key presses
















Fig.12 Fiber stretch sensors to measure body movements




4.FUTURE TRENDS
By providing the platform for a suite of sensors that can be utilized to monitor an
individual unobtrusively. Smart Shirt technology opens up existing opportunities to develop
adaptive and responsive systems that can think and act based on the users condition, stimuli
and environment. Thus, the rich vital signs delta steam from the smart shirt can be used to design
and experiment real-time feedback mechanism (as part of the smart shirt system) to embrace the
quality of care for this individual by providing appropriate and timely medical inspections.

Certain individuals are susceptible to anaphylaxis reaction (an allergic reaction) when stung
by a bee or spider and need a shot of epinephrine (adrenaline) immediately to prevent above illness
or even fatalities. By applying advancement in MEMS (Micro-Electromechanical Systems)
technology, a feedback system including a dry delivery system-can be integrated into the smart
shirt. Of course mechanism to guard against inadvertent administration of dry can be built as a part
of the control system.

Likewise, the Smart shirts delta acquisition capabilities can be used to detect the condition
when an individual is lapsing into a diabetic shock and this integrated feedback mechanism can
provide the appropriate response to prevent a fatality. Thus, the smart shirt represents yet another
significant milestone in the endeavor to save and enhance the quality of human life through the use
of advanced technologies.
DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


5. CONCLUSION

The ring sensor and smart shirt are an effective and comfortable, and mobile information
infrastructure that can be made to the individuals requirements to take advantage of the
advancements in telemedicine and information processing. Just as special-purpose chips and
processors can be plugged into a computer motherboard to obtain the required information
processing capability, the smart shirt is an information infrastructure into which the wearer can
plug in the desired sensors and devices, thereby creating a system for monitoring vital signs in an
efficient and cost effective manner with the universal interface of clothing.

Advanced technologies such as the smart shirt have at partial to dramatically alter its
landscape of healthcare delivery and at practice of medicine as we know them today. By enhancing
the quality of life, minimizing medical errors, and reducing healthcare costs, the patient-control
wearable information infrastructure can play a vital role in realizing the future healthcare system.
Just as the spreadsheet pioneered the field of information processing that brought computing to the
masses. It is anticipated that the smart shirt will bring personalized and affordable healthcare
monitoring to the population at large, thus leading to the realization of Affordable Healthcare, Any
place, Anytime, Anyone.

DEVELOPMENT OF WEARABLE BIOSENSOR SEMINAR REPORT
DEPT. OF ELEC. KURUKSHETRA UNIVERSITY


6.REFERENCES
1. https://www.google.co
2. Handbook of biomedical instrumentation ,Khandpur ,pp-138,233,238
3. R.Neuman,biomedical sensors,handbook of biomedical instrumentation,pp-725-755
4. http://www.smartshirt.gatech.edu
5. http://www.wearables.gatech.edu

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