Scribd
Upload
53 views2 pages

Antibiotice

1. Beta-lactam antibiotics like penicillins inhibit the synthesis of bacterial cell walls by blocking peptidoglycan synthesis. They are effective against many gram-positive and gram-negative bacteria. 2. Cephalosporins are also cell wall synthesis inhibitors and are divided into generations based on their spectrum of activity. Later generations have broader spectra that include more resistant gram-negative bacteria. 3. Combining antibiotics with different mechanisms of action or combining a bactericidal and bacteriostatic antibiotic can create a synergistic effect against certain pathogens.

Uploaded by

Simona Timofte
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
53 views2 pages

Antibiotice

1. Beta-lactam antibiotics like penicillins inhibit the synthesis of bacterial cell walls by blocking peptidoglycan synthesis. They are effective against many gram-positive and gram-negative bacteria. 2. Cephalosporins are also cell wall synthesis inhibitors and are divided into generations based on their spectrum of activity. Later generations have broader spectra that include more resistant gram-negative bacteria. 3. Combining antibiotics with different mechanisms of action or combining a bactericidal and bacteriostatic antibiotic can create a synergistic effect against certain pathogens.

Uploaded by

Simona Timofte
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
You are on page 1/ 2

A.

INHIBITORI AI SINTEZEI PERETELUI CELULAR


I. INHIBA SINTEZA PEPTIDOGLICANULUI SUNT BETA LACTAMICE
PENICILINE De Benzil-penicilina CG+ / BG+ /CG-
biosinteza Benzatin-penicilina BcAnaero exceptie:
Fenoximetil-penici. -spirochete
Procaina-penicilina -Bacteroides fragilis
De Pen. rez la -Meticilina Stafilococi producatori
semisinteza penicilinaza - oxacilina de penicilinaza.
Bactericide toate stafilococica - nafcilina
beta – lactamice (grup M) - cloxacilina
- dicloxacilina
Aminopeniciline -Ampicilina CG+ / BG+ /CG
grup A -Amoxicilina BcAnaero,
-Bacampicilina BG- : H.i,E.Coli,
Salmonela
Shigella
Proteus
Peniciline cu Carboxipen:Ticarcilina CG+ / BG+ /CG
spectu largit Ureidopen: Azlocilina BcAnaero,
BG- : H.i,E.Coli,
Salmonela
Shigella
Proteus
Klebsiella, Enterobact,
Seratia, Pseudom.
Peniciline Ampicilina+sulbactam Staphyilococcus,E.coli,
asociate cu inhib. Amoxa+ac.clavulanic Gonorrhoeae,
de beta- Ticarcilina+ac.clavul. klebsiella
lactamaze Haemophilus,Shigella,
Neisseria,Salmonella,B
acteroides fragilis
CEFALOSPORINE Generatia I I.v: cefalotina, CG+ / BG+ /CG
Cefazolina BcAnaerobe,
Cefapirina BG- : H.i,E.Coli,
Oral:cefalexina Salmonela
Shigella
Cefadroxil
Proteus
cefradin Klebsiella, Staf prod de
penicilinaza
/H.i,anaerobi,enteroc.
Listeria
Generatia II Cefalosporine Iv:-cefuroxim CG+ / BG+ /CG
propriu-zise: - cefunocid BG- : H.i,E.Coli,
- cefamandol Salmonela
- ceforanid Shigella
Proteus
Oral: - cefaclor
Klebsiella, Staf prod de
- cefprozil penicilinaza,Hi,Enterob,
- cefuroxima- Serratia,Proteus
axetil
Cefamicine Iv: -cefoxitina CG+ / BG+ /CG
- cefmetazol BcAnaerobe,
- cefotetan BG- : H.i,E.Coli,
Salmonela
Shigella
Proteus
Klebsiella, Staf prod de
penicilinaza,Hi,Enterob,
Serratia,Proteus
1
Generatia III Iv: -cefotaxima CG+ / BG+ /CG
- ceftriaxona BcAnaerobe,
- ceftizoxima
C.I - asocierea unui antibiotic BACTERICID – BACTERIOSTATIC (penicilina-tetraciclina)
- antib cu mecanism de actiune identice (2 beta lactamice )
- AMGZ. CU POLIMIXINE

- EFECT SINERGIC: AMPICILINA + GENTAMICINA -ENETROCOCI SI STREPTOCOCI


TICARCILINA + AMGZ - P.AERUGINOSA
CEFALOSPORINE + AMGZ -K.PENUMONIAE

You might also like

pFad - Phonifier reborn

Pfad - The Proxy pFad of © 2024 Garber Painting. All rights reserved.

Note: This service is not intended for secure transactions such as banking, social media, email, or purchasing. Use at your own risk. We assume no liability whatsoever for broken pages.


Alternative Proxies:

Alternative Proxy

pFad Proxy

pFad v3 Proxy

pFad v4 Proxy