INDUSTRIAL PHARMACY-I

1. Unequal distribution of color on the surface of tablet is called

a. Weight Variation
b. Capping
c. Mottling
d. Picking
2. Tablets place under the tongue where they dissolve and disintegrate
a. Enteric coated tablet
b. Dispensing tablet
c. Chewable tablet
d. Sublingual tablet
3. According to BCS classification , the drugs having low solubility and high permeability are
classified in
a. Class I
b. Class II
c. Class III
d. Class IV
4. Compound having Hausner’s ratio less than 1.25 indicates
a. Poor flow
b. Excellent flow
c. Good flow
d. High flow
5. ........... is the ratio of the mean residence time to the absorption time
a. Absorption number
b. Dissolution number
c. Dose number
d. Intrinsic dissolution
6. Which of the following is not used as diluents?
a. Lactose
b. Microcrystalline cellulose
c. Calcium Carbonate
d. Poly Vinyl Pyrrolidone
7. Disintegration time for film coated tablet is
a. 15 min.
b. 30 min.
c. 60 min.
d. 120 min.
8. Dry gum method is also known as
a. Continental method
b. English method
c. Bottle method
d. Forbes method
9. Powders having carr's index(%) greater than 40 shows
a. Excellent flow
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b. Good flow
c. Passable flow
d. Very very poor flow
10. According to IP, the limit of wt. variation for tablet having avg. wt. less than 80 mg is
a. 10%
b. 7.5%
c. 5%
d. 15%
11. The powder flow is said to be excellent if angle of repose (in degrees) is
a. < 25
b. 31-35
c. 36-40
d. > 40
12. Hausner's Ratio is
a. Tapped density/ Bulk density
b. Bulk density/ Tapped density
c. Bulk density/ Void density
d. Void density/ Bulk density
13. Bull's- eye tablet is
a. Layered tablets
b. Inlay tablets
c. Compression coated tablet
d. None of the above
14. For sugar coated tablet, specified disintegration time is
a. 15 min.
b. 30 min.
c. 60 min.
d. 120 min.
15. On commercial scale, emulsion are prepared by
a. Centrifugation
b. Dialysis
c. Freezing
d. Homogenization
16. Apparatus use for the evaluation of tablet friability
a. Monsanto tester
b. Roche friabilator
c. Disintegration apparatus
d. Rotary tablet press
17. Following is the method of particle size measurement
a. Sieving
b. Compressibility
c. Hygroscopicity
d. Bioavailability
18. ........ is a defect in which film of a tablet become dull or hazed after a prolonged period of
storage
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a. Chipping
b. Blooming
c. Blushing
d. Blistering
19. Which of the following method preferably prepared for manufacturing of aspirin?
a. Direct Compression
b. Wet granulation
c. Dry granulation
d. Both a & c
20. pH of the solution depends on
a. Henderson-Hasselbalch equation
b. Henty's law
c. Charle' s law
d. Dalton's law
21. Soft gelatin capsule consist of
a. Body and cap
b. Single Piece (no cap and body)
c. Both A & B
d. None of the above
22. Which one of the following is not a route of administration?
a. Intravenous (IV)
b. Oral
c. Topical
d. Dissolution
23. These tablet bypass the stomach and disintegrate in the intestine
a. Buccal tablet
b. Enteric coated tablet
c. Effervescent tablets
d. Vaginal tablets
24. Which of the following is used as vulcanizing agent in manufacture of rubber closure?
a. Sulphur
b. Activated carbon black
c. Talc
d. Stearic acid
25. Type III glass is also known as
a. Soda lime glass
b. General purpose soda lime glass
c. Borosilicate glass
d. Treated soda lime glass
26. The term PSIG in reference to aerosols means
a. Propellant safety in glass
b. Pound per square inch gauge
c. per square inch of glass
d. Atmospheric pressure
27. Which of the following technique is used for formation of pellets?
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a. Extrusion
b. Spheronization
c. Both A & B
d. None
28. The segregation of tablet into two or more layers is termed as
a. Capping
b. Lamination
c. Chipping
d. Cracking
29. Clear, sweetened hydro alcoholic solution is?
a. Draught
b. Drops
c. Linctuses
d. Elixirs
30. Which animal is used in pyrogen test?
a. Mice
b. Rabbit
c. Cat
d. Rat
31. This ingredient is added to improve the flowability of the powder
a. Glidant
b. Sorbent
c. Colorant
d. Disintegrant
32. Ingredient used to increase the viscosity of eye drops
a. Buffers
b. Preservative
c. Thickening agent
d. None of the above
33. An ideal cream should be free from
a. Glossy look
b. Smoothness
c. Grittiness
d. None of the above
34. In Vanishing Cream Glycerin acts as
a. Buffer
b. Humectant
c. Antioxidant
d. Vehicle
35. According BCS , the drugs have low solubility and low permeability belongs to
a. Class I
b. Class II
c. Class III
d. Class IV
36. High efficiency particulate air filter remove particles up to size
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a. 0.1mm
b. 0.3 micron
c. 0.001 micron
d. 0.1 micron
37. The instrument used to measure the thickness of tablet is
a. Vernier Caliper
b. Micrometer
c. Both A & B
d. None of the above
38. Cam tracks are used in tablet compression machine for
a. Feeding the granules
b. Guiding the movement of punches
c. Compressing the granules
d. Fixing the Shape
39. For sterility testing which of the following media is/are used
a. Soya-bean casein digest
b. Fluid thioglycollate media
c. Both A & B
d. None of these
40. Which of the following propellant used for topical pharmaceutical aerosols?
a. Trichloro monofluoro methane
b. Propane
c. Dichloro difluoro methane
d. Dichloro tetra fluoro ethane
41. A disintegration instrument consists of following chambers
a. 3
b. 2
c. 6
d. 8
42. Diptube of aerosol container is made from
a. Polypropylene
b. Glass
c. Stainless steel
d. Aluminium
43. Which of the following is most effective Sunscreen?
a. PABA
b. Titanium dioxide
c. Ferric oxide
d. Methyl Salicylate
44. According to IP, disintegration time for Soft Gelatin Capsule is
a. 60 min.
b. 15 min.
c. 30 min.
d. 5 min
45. Which apparatus is used to determine flash point of aerosol products
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a. Coulter counter
b. Tag open cup apparatus
c. Rheometer
d. Osmometer
46. Preliminary test (Rabbits) for Pyrogens is also known as
a. LAL Test
b. SHAM Test
c. BET Test
d. None of the above
47. Isoelectric point of Type A Gelatin is
a. Between 12-15
b. Between 7-9
c. Between 4.7-5.3
d. 10
48. Wet gum method is also known as
a. Continental method
b. English method
c. Bottle method
d. Forbe's method
49. In Sugar coating, the step done to round up the edges of the tablet is
a. Sealing
b. Smoothing
c. Sub-coating
d. Polishing
50. Powder flow properties are characterized by
a. Angle of repose
b. Carr's index
c. Hausner ratio
d. All the above

51. Green Bone is used for the preparation of a which type of gelatin
a. A
b. B
c. C
d. Both A & B
52. According to IP, disintegration time for Hard Gelatin Capsule is
a. 60 min.
b. 15 min.
c. 30 min.
d. 5 min.
53. Preliminary test (Rabbits) for Pyrogens is also known as
a. LAL Test
b. SHAM Test
c. BET Test
d. None of the above
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54. Vanishing cream is ------ type of emulsion

a. o/w type
b. w/o type
c. Microemulsion
d. Multiple emulsion
55. Select the thermosetting type of Plastic
a. Nylon
b. Polystyrene
c. Polypropylene
d. Polyurethanes
56. The gel strength of gelatin should be in range of
a. 150- 250 Bloom grams
b. 80-120 Bloom grams
c. 350- 480 Bloom grams
d. 100- 200 Bloom grams
57. The gas used in Cryopelletization is
a. Hydrogen
b. Nitrogen
c. Oxygen
d. Carbon Dioxide
58. An Injection into Subarchnoid space is known as
a. Intra-articular injection
b. Intra-cisternal injection
c. Intra-athecal injection
d. Intra-arterial injection
59. A common type of Surfactant used in baby shampoos is
a. Anionic surfactants
b. Non- ionic surfactants
c. Cationic surfactants
d. Amphoteric surfactants
60. Empty Capsules has moisture content in the range of
a. 60%
b. 12- 15%
c. 50- 70%
d. 30%
61. Ball growth phase is called as
a. Abrasion transfer phase
b. Layering phase
c. Coalescence phase
d. Nucleation phase
62. Medium for aerobic bacteria and fungi is
a. Fluid thioglycolate medium
b. Soyabean casein digest medium
c. Both A & B
d. None of these
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63. Water attack test is used to test ........ type of glass

a. Type I
b. Type II
c. Type III
d. NP Type
64. Isoelectric point of Type B Gelatin is
a. Between 12-15
b. Between 7-9
c. Between 4.7-5.3
d. 10
65. In pharmaceutical aerosols the identification of propellants is carried out by
a. Tag Open Cup apparatus
b. Pycnometer
c. Cascade Impactor
d. Gas Chromatography
66. Which of the following is used as preservative in ophthalmic preparation
a. Phenol
b. Benzoic Acid
c. Benzalkonium Chloride
d. Chlorocresol
67. In pellet formation, the state where air start to dispersed continuously throughout the
agglomerate is
a. Pendular state
b. Funicular state
c. Capillary state
d. Droplets
68. The following ingredient is a bulking agent in lyophilized product
a. Mannitol
b. Aspartame
c. Benzalkonium Chloride
d. Zinc Chloride
69. ......... is also known as hermetic container
a. Multi-dose Container
b. Air-tight Container
c. Well-closed container
d. Aerosol container
70. While performing leakage test the coloring agent preferred is
a. 0.1% methylene blue
b. 1% methylene blue
c. 0.2% methylene blue
d. 2% methylene blue
71. The liquefied gas propellant Dichlorodifluoromethane is
a. Propellant 11
b. Propellant 12
c. Propellant 114
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d. Propellant 21
72. In Shampoos, Zinc Pyrithione (ZPTO) is used as
a. Foam Booster
b. Pearlscent Agent
c. Sequestrant
d. Anti-Dandruff Agent
73. Non-Actinic glass is a
a. Flint Glass
b. Amber coloured glass
c. Both A & B
d. None of these
74. Which of the following is an example of Humectant
a. Sodium Alginate
b. Aspartame
c. Sorbitol
d. Gum tragacanth
75. If the Average mass (mg) of capsule is less than 300, then allowed % deviated weight variation
is
a. 5%
b. 7.5%
c. 10%
d. 15%
76. To assess the resistant of tablet to abrasion, the test performed is known as
a. Friability
b. Hardness
c. Disintegration
d. None of the above
77. The ratio of ultimate volume to the actual volume of sediment is termed as
a. Sedimentation volume
b. Degree of flocculation
c. Emulsification volume
d. Phase volume ratio
78. Tablet are coated
a. To protect the drug from external environment
b. To mask bitter taste
c. To make swallowing easier
d. All the above
79. Adhesion of tablet material to die wall is called
a. Mottling
b. Sticking
c. Picking
d. Capping
80. Eye irritation study of ophthalmic products is done by
a. Sterility test
b. Draize test
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c. Endotoxin study
d. Particle size analysis