Whizzology 1N (
Whizzology 1N (
Whizzology 1N (
Dr Nuke first came to notoriety in the 1960s with his pioneering drug testing work with beagles.
The limitations of these experiments lay in the beagles’ inability to provide subjective feedback
(commonly known as talking). It was alleged that random samples of students were then
kidnapped, locked in the beagles’ cages and forced to use a variety of mind expanding drugs.
These allegations only came to light after the subsequent riot when the students refused to
leave their cages at the end of the experiment. Shunned by the scientific community, Dr Nuke
set up his secret underground drug lab, where he continues with his search for the ultimate
pleasure chemicals.
On my birthday, I decided to hold a party where my friends were invited to bring along
some amphetamine. One had a handful of pills called dexies, another said he had
methamphetamine; another brought a little greasy blob saying it’s base; two turned up with
white crystals, one said it was ice, the other said it was crank, finally my cousin arrived back
from her trip to Eastern Europe with some vint. By this time they weren’t sure if they should
snort it, smoke it or clean the kitchen sink with it. But, fear not, my stimulant fancying friends,
for I have written this little booklet to help them and you understand amphetamine and its
chemical relatives and give you some advice about using these substances in a safer way.
Let’s start by looking at....
Stimulants are drugs which speed up your mind and body, making you more alert, energetic
and talkative. Weaker stimulants include nicotine (in tobacco) and caffeine (in tea, coffee,
chocolate, cola, guarana, etc.). The caffeine and guarana in a can of Red Bull might give
you wings, but people use the stronger stimulants to really start flying. The two major groups
of stimulants are the cocaine and the amphetamine family of drugs. Another group of
drugs related to amphetamine is the phenylalkylamines. These have both stimulant and
hallucinogenic effects – the most famous of these is methylenedioxymethamphetamine,
MDMA for short, better know as ecstasy. You won’t be hearing much about ‘E’ as that side of
the family always gets the attention.
amphetamine sulphate
Amphetamine sulphate is a mixture of two chemical compounds. Let me introduce you
to the chemical brothers Laevo (laevo-amphetamine) and Dextro (dextro-amphetamine,
usually shortened to dexamphetamine). Laevo and Dextro are almost identical twins, laevo-
amphetamine has a weaker and more physical effect, while dextro-amphetamine has a
stronger and more psychological (in the mind) effect. In short Dextro is a party animal, you’d
want to hang out with while Laevo is a bit of a ‘Billy no-mates’.
amphetamine paste/base
Amphetamine sulphate is usually around 5% pure. If you
could get hold of it before all the rest of the shit is added to
it you’d have a pretty strong drug. Well that’s the theory, the
reality is a bit different. Base and paste are slang names
for a stronger form of illicit racemic amphetamine sulphate.
Although in a far purer (stronger) form than standard street
speed powder, base or paste is still cut. The purity of paste
is typically between 15% and 20%. Forensic analyses
of paste seized by the police also show that a common
adulterant is magnesium stearate (used in candles), which
explains the usual appearance of this speed product (damp
and waxy). Whilst paste is usually stronger, remember that
if you let it dry out, you would lose more than a third of its
weight. Paste sells for between £15 and £30 per gram.
dexamphetamine
Dextroamphetamine sulphate (dexamphetamine) is purified
amphetamine sulphate (i.e. the dexamphetamine is separated
out, and the laevo-amphetamine is discarded). It is produced
by drug companies as Dexedrine tablets or ‘Dexies Midnight
Runners’. Diverted (stolen) from chemists, they were the fuel
of the mod and northern soul scene of the 1960’s. Dexedrine
is the only kind of stimulant amphetamine currently prescribed
in Britain - in the form of 5mg tablets or syrup. The tablets
are white, scored and marked ‘Evans’ and sell for £1-2 each.
Though medical authorities recommend it for the treatment
of narcolepsy and hyperactivity in children only, it is also
prescribed to illicit speed users at about a dozen drug clinics in
the UK as a harm reduction intervention - that is, to
prevent use or injection of illicit street speed.
KEY. Start with amphetamine sulphate; A blue arrow shows if Laevo or Dextro have been
separated. A red arrow shows a change in chemical structure. A move to the left means the
drug is less speedy: a move to the right and it is more speedy. A move up and the drug is
more ‘in the mind’ ; a move down and it is more physical.
other amphetamine-like drugs
Two chemical cousins which do not fit so neatly into the family of amphetamines are
cathinone and cathine, which are amphetamine-like drugs found in the leaves of khat (or
qat). In Britain, they are only illegal if they are extracted from the plant or made synthetically.
Khat is a shrub which was originally grown and chewed in North Eastern Africa, and whose
use later spread to Yemen. Immigrants from these areas have also brought the khat habit to
Western people - including the younger residents of British cities like London, Birmingham and
Liverpool.
Lastly, a recent example of a semi-synthetic cousin of amphetamine is methylcathinone, which
can be manufactured from cathinone. Broadly speaking, methylcathinone is to cathinone what
methylamphetamine is to amphetamine - for instance, it gives a longer and “better” buzz. In
the USA it is known by the slang names of “cat”, “goob” and “morning star”, and has become
the new “demon drug” in the mass media in California and some other states.
effects of amphetamines
The main positive effects of amphetamines include increased energy, alertness, euphoria and
sociability, while the main negative effects are the come-down (fatigue, depression), paranoia
and insomnia. Though the effects on mind and body are interrelated, it is easier to understand
if they are looked at separately.
intensified mood
improved awareness
and perceptions
greater sociability
and talkativeness
changes to
appearance
of eyes
muscular
tension
dry mouth,
lips, and eyes
slight increase in
physical strength
lack of hunger
Involuntary evacuation
of bladder & bowels -
whilst this is part of the
flight or fight mechanism
mimicked by the effects
increased body temperature - of speed, in reality unless
but cold feet and hands caught red handed by
your mum or a dealer
you owe money to this
is unlikely- it is included
here purely for cheap
comic effect.
The main physical effects of amphetamine are:
After amphetamines have done their job in the brain, they are broken down by the
body into metabolites (simpler chemical structures), and mainly excreted in piss and
sweat over a 48 hour period (but mostly within 24 hours). Like other drug users,
some speed users facing urine tests for drugs attempt to accelerate the excretion of
amphetamines from their body by various methods - including drinking large amounts
of water, acidifying their urine by consuming fruit juices, consuming lots of caffeine, or
taking prescription diuretics – all of which boost excretion of amphetamine metabolites
through increased urination.
the comedown
Speed works by releasing the body’s stored energy reserves - so rather than giving you “free’
chemical energy, it allows you to “borrow” energy from the next day. Consequently, speeding
for a single day/night generally leads to a come-down lasting about another day, while speed
runs of several days can lead to a major come-down of a similar length known as a ‘crash’.
The come-down is based on physical and mental tiredness - a kind of
severe fatigue brought about by the fact that you used up today’s energy
yesterday. The after-effects on the body include jaw ache, sensitivity
to light, cracked lips, dry or spotty skin, upset stomach, dizziness and
aching muscles - including backache, which often leads neurotic people
on a come-down into worrying that they have damaged their kidneys.
The come-down effects on the mind
include feeling tired, confused, hungry,
depressed, irritable, wallowing in self-
pity and lacking concentration (especially
forgetting words). Following a speed
run/binge of several days, users may fall
asleep suddenly (crash) and stay asleep
for 24 hours or longer.
effects on particular activities
driving.
Moderate doses of amphetamine make you more alert and quick to react. This improves vari-
ous skills relevant to driving (which is why military pilots have often been given amphetamines
before embarking on missions). However, users tend to over-estimate their driving ability and
take more risks, including driving too fast – which means that speeding can lead to speeding!
As the amphetamine wears off and the come-down kicks in, users are most likely to show
dodgy driving behavior.
sex.
Although everybody is different in what turns them on, amphetamine sulphate is not generally
known as an aphrodisiac; methamphetamine on the other hand, is far more likely to start a
party in your pants. In Russia they have a type of methamphetamine known on the streets
as ‘vint’, vint is the Russian word for ‘shag’ and is associated with group sex sessions.
Crystal meth is starting to appear in Britain, much of it bought in small amounts from the
gay bathhouses of San Francisco or Sydney, where it is also associated with group sex. This
does not mean however, that methamphetamine will turn you into a ‘lurve slave’; group sex is
surprisingly common in Russia and gay men don’t need any excuse to start shagging.
the law
Pseudo-amphetamines can be obtained with a prescription
or brought over the counter at chemists and many are not
covered by the main drug law ‘The Misuse of Drugs Act’.
Amphetamines can be prescribed by doctors, and legally
dispensed by pharmacists to people with a prescription.
However, prescribing of amphetamines is effectively
restricted to dexamphetamine in tablets or syrup
(methamphetamine can only be dispensed from
hospital pharmacies).
health
Some experts claim that occasional or moderate use is not harmful to most people’s health.
However, heavy use, or prolonged moderate use, may damage the cardiovascular system
(heart), the immune system and/or central nervous system. First, constant strain on the
cardiovascular system may lead to high blood pressure, irregular heart rhythm and even
stroke. Second, like most drugs, amphetamines reduce the efficiency of the immune system.
Combined with poorer eating and sleeping habits, this can substantially increase the risks of
infection and illness in regular users. Third, there is evidence that high doses of amphetamine,
particularly methamphetamine, produce dopaminergic nerve terminal degeneration (sounds
nasty!). Though some sources claim that such brain damage is irreversible, the evidence is not
conclusive. Lastly, injecting speed or any drug is associated with particular health problems,
including damage to the veins and transmission of infectious diseases (e.g. HIV, hepatitis).
addiction
Although there is a tolerance with amphetamine (over time, it takes more of the drug to
get the same effect), amphetamine use does not cause physical addiction – like heroin or
cigarettes - so, there is no need to detoxify (slowly reducing the amount you use). A long-term
regular user can just stop completely, although they will experience come-down effects for
several days to several months depending on the scale and size of their habit – and how much
sleep, rest and food they have missed. Regular users often report a craving for the drug (a
strong desire to use). However, compared with heroin, crack and tranquillizers, it is relatively
easy to stop using amphetamines. Mild to moderate depression is the main unpleasant after-
effect experienced by people giving up a speed habit - more serious cases are usually helped
by anti-depressants like Prozac.
amphetamine psychosis?
Unlike true psychosis, amphetamine psychosis
does not usually affect your memory or your
sense of the passage of time, or your identity
(who am I, where am I? etc). It is characterized
by depression which may alternate with
euphoria; suicidal thoughts are common. The
idea of amphetamine psychosis is based on
three core symptoms:
Ideas of reference: believing that particular objects or
events have special, personal meanings - for example,
the words of a song on the radio contain a message
for you.
you;
Your sex, weight, how your body deals with drugs (metabolism) and your
tolerance (how much you are used to taking);.
the drug:
how it is taken (e.g. sniffed, injected etc); how much of it you have taken and how
pure it is.
Lethal doses:
for non-tolerant (new or occasional) users may start at around 50-100 mgs (1 to 2 grams of
5% pure amphetamine sulphate) for a small, susceptible person, while regular users who have
developed tolerance may require doses of several
hundred milligrams before fatal overdose becomes
likely.
death
“Speed Kills” was an anti-drug slogan in the 1960’s - but does speed really kill? In the
second half of the 90s, about 3,000-4,000 people a year attended health services for help
with problems related to their speed use. The official number of speed deaths in the UK
climbed from five or six a year in the late 80s, to 20-25 a year in the first half of the 90s, and
then to about 40 a year from the mid to late 90’s. This is similar to the death rate for cocaine.
Deaths related to amphetamines are generally caused by fatal overdoses, though also include
accidents and disease (e.g. HIV infection from sharing used needles). Many speed-related
deaths are similar to ecstasy deaths, which receive more attention in the mass media – that
is, they are based on heatstroke, hyperthermia, and blood thinning/clotting, followed by brain
seizures, heart attacks or kidney failure. Although the risk of death from taking speed is
relatively low compared to a drug like heroin, speed can and does kill people.
part 4 TOP TIPS FOR SAFER SPEEDING
The only way to avoid any risk of harm from speed is not to use it. People who should
particularly avoid speed are those with psychiatric problems, respiratory complaints (eg.
asthma), and heart conditions (e.g. palpitations). There are many other healthier or at least
less risky ways of feeling ‘stimulated’, including physical exercise, mental techniques like
meditation, or using minor stimulants like caffeine. For those determined to take speed
anyway, the following advice should help reduce the risks of harmful consequences
moderation
Use occasionally – avoid using more than once a week, avoid using two or more
days in a row – allow your body to recover
Use moderate doses – physical side-effects are the main thing which increase with
the dose, and larger amounts can make you more jittery than
stimulated
Accidental overdose – check the strength and quality of a particular batch by asking
others who have taken it what they thought of it – err on the
side of caution when you have a new batch of speed: you can
always take more but you cannot take less.
reducing risk
Swallowing speed – is the least risky method of use (wrapped in a cigarette paper
or dissolved in a drink). Sniffing speed is the next least risky
method, though to minimize damage to the nasal membranes
its best to (a) start by chopping the powder up finely on a
mirror or such like, and (b) finish by rinsing your nose out with
water.
Smoking & injecting- are the most likely to result in overdose if you inhale/inject
too much in one go. Injecting is the most risky method for
well-know reasons. The main things to remember are: (a) be
hygienic, and (b) never use injecting equipment already used
by someone else. If you are injecting speed, it is important to
rotate the places on your body where you inject. It is a good
idea to visit a drug agency and get some advice on your
injection technique
Don’t talk shite– resist the temptation to say everything that you think about on
speed, and remember that interesting conversation involves
(a) saying only the best things you think of, and (b) listening
to other people as well as talking to them (and not constantly
interrupting them or talking them down). Don’t run the risk of
speed turning you into a bore.
staying healthy
Avoid losing too much sleep by taking speed at least 8 hours before bedtime,
and preferably over 12 hours before – don’t get into the habit of using sleeping pills,
alcohol or opiates (heroin etc) to get to sleep or feel better afterwards
Try to eat and drink as you normally would – if your appetite is suppressed, drink
a little more liquids than you normally would, and try eating easily swallowable food
like fruit, yoghurt etc. – though avoid anything with the red food dye tyramine (mixed
with speed, it can make you feel ill). Regular users are strongly advised to take
vitamin and mineral supplements.
Avoid overheating or overexerting yourself. Like the advice for ecstasy users: if
you are dancing at a club, remember to chill out and sip water/juice regularly (don’t
drink large amounts in one go). Even though you may feel like you have boundless
energy, remember to take rest, especially if involved in physical work or exercise.
Avoid mixing speed with other drugs, particularly alcohol (which also dehydrates
you) and beta-blockers (which can interact badly with speed) and watch your cigarette
smoking, which can increase dramatically when speeding. You’ll wake up with a
comedown, hangover and chesty cough combined.
Always carry condoms (just in case). The number of young people catching
sexually transmitted diseases is rocketing. Condoms and lubricant prevent chaffing,
disease and pregnancy
Stay with them and calm them if they are conscious: if they are unconscious put
them on their side so that they don’t choke on their vomit (the recovery position).
Check there is nothing stopping them from breathing (like false teeth or gum). Check
their pulse and breathing and administer first aid if you know how. Always tell medics
and paramedics everything you know about the drugs that the person has taken. This
could save their life. If you regularly use with friends talk through what you would do in
an emergency.