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Celiac Disease Facts and Figures

Celiac disease is an inherited autoimmune disorder that


affects the digestive process of the small intestine. When
a person who has celiac disease consumes gluten, a
protein found in wheat, rye and barley, the individual’s
immune system responds by attacking the small intestine
and inhibiting the absorption of important nutrients into
the body. Undiagnosed and untreated, celiac disease can
lead to the development of other autoimmune disorders,
as well as osteoporosis, infertility, neurological conditions
and in rare cases, cancer.
Prevalence of Celiac Disease in the •  eliac disease affects at least 3 million
C
United States Americans.
• The average length of time it takes for a
• In average healthy people: 1 in 133 symptomatic person to be diagnosed with
• In people with related symptoms: 1 in 56 celiac disease in the US is four years;
• In people with first-degree relatives this type of delay dramatically increases
(parent, child, sibling) who are celiac: 1 an individual’s risk of developing
in 22 autoimmune disorders, neurological
• In people with second-degree relatives problems, osteoporosis and even cancer.
(aunt, uncle, cousin) who are celiac: 1 in
39 Source: Characteristics of adult celiac disease in the
USA: results of a national survey. Green, P.H. et.al.
• Estimated prevalence for African-, American Journal of Gastroenterology, 2001, 2006.
Hispanic- and Asian-Americans: 1 in 236
• In the landmark prevalence study on •  he incidence of autoimmune diseases
T
celiac disease, investigators determined in the general US population is 3.5%.
that 60% of children and 41% of In a 1999 study, Ventura, et.al. found
adults diagnosed during the study were that those diagnosed with celiac disease
asymptomatic (without any symptoms). between 2-4 years of age had a 10.5%
• During the prevalence study, researchers chance of developing an autoimmune
found that 21% of patients with a positive disorder. Additional findings are outlined
anti-endomysial antibody test could not in the table below:
receive a biopsy due to the refusal of their
physician to perform the procedure or the Age at diagnosis Chance of developing
insurance company to pay for it. autoimmune condition
• Only 35% of newly diagnosed patients 4 – 12 yrs of age 16.7%
had chronic diarrhea, dispelling the myth 12 – 20 yrs of age 27%
that diarrhea must be present to diagnose Over 20 yrs of age 34%
celiac disease.

Source: A multi-center study on the sero-prevalence • E


 arly diagnosis of celiac disease thus
of celiac disease in the United States among both at
risk and not at risk groups. Fasano et. al., Archives of is important, as it might prevent com-
Internal Medicine. February 2003. plications, and awareness is the key.
A recent study in North America shows (42,000) of them also have celiac
that an active case-finding strategy in the disease.
primary care setting is an effective means • The number of people with celiac disease
to improve the diagnostic rate of Celiac
in the U.S. would fill 4,400 Boeing 747
Disease: by screening with the blood test
airplanes.
all subjects belonging to known “at-risk” • It would take 936 cruise ships to hold
groups such as those listed above, the
every American with celiac disease.
diagnosis rates increased more than 40- • Americans with celiac disease could fill
folds.
Comiskey Park (now US Cellular Field,
Source: Duration of exposure to gluten and risk for with 40,000 seats) to watch the Chicago
autoimmune disorders in patients with celiac disease. White Sox 55 times.
SIGEP Study Group for Autoimmune Disorders in • U.S. fans with celiac disease could fill
Celiac Disease. Ventura A, et.al. Gastroenterology 1999
Aug;117(2):297-303. Rampertab SD et al. Trends in Soldier Field, the home of the Chicago
the Presentation of Celiac Disease Am J Medicine 2006 Bears, 37 times.
Catassi C et al. Detection of Celiac disease in primary • The number of people with celiac disease
care: a multicenter case-finding study in North America.
Am J Gastroenterol 2007 in the U.S. is roughly equal to the number
of people living in the state of Nevada.
Celiac disease affects 1% of healthy, • Alaska, Delaware, Washington DC,

Hawaii, Idaho, Maine, Montana,


average Americans. That means at
Nebraska, New Hampshire, New Mexico,
least 3 million people in our country North Dakota, Rhode Island, South
are living with celiac disease—97% Dakota, Utah and Vermont all have
of them are undiagnosed. populations that are less than 2,200,000
the number of people living with celiac
disease in the United States.
Chronic Illness in the United States
Below is a list of some commonly known
chronic illnesses and the number of people Facts about the Gluten-Free Diet
affected in the United States: • In 2004 the Food Allergen Labeling and
• Epilepsy affects 2.7 million Consumer Protection Act became law.
• Cystic Fibrosis affects 30,000 people This legislation went into effect in 2006
• 17,000 people are living with hemophilia and makes it possible, for the first time,
• Parkinson’s disease affects 1,000,000 for people with celiac disease to read a
individuals food label and determine in a few easy
• Ulcerative colitis affects 500,000 people steps if a product is safe to eat. The
• Crohn’s disease affects 500,000 University of Chicago Celiac Disease
Americans Center helped to pass this law.
• 2.1 million Americans are living with • There are more than 2,000 gluten free

rheumatoid arthritis food items available in the United States,


• Lupus affects 1.5 million people and consumers are more likely to find
• Multiple sclerosis affects 400,000 these foods in regular grocery stores.
people in the United States • From 2004 – 2005, sales of gluten-free

foods increased by 77.8 million dollars (a


growth of 14.6%).
Putting Celiac Disease in Perspective • T
 he US Department of Agriculture

• Type 1 Diabetes affects 3 million people; projects that the gluten-free industries
6% (180,000) of those diagnosed also revenues will reach $1.7 Billion by 2010.
have celiac disease.
• 610,000 women in the US experience Data from www.bakingbusiness.com August 2005.
unexplained infertility; 6% (36,600)
of these women might never learn that For more information contact the
celiac disease is the cause. University of Chicago Celiac
• 350,000 people in the United States Disease Center at 773.702.7593
are living with Down Syndrome; 12% or www.CeliacDisease.net.

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