Venous Thromboembolism
Venous Thromboembolism
Venous Thromboembolism
Thromboembolism
By:
Bonita, Rica B.
Navera, Krsna B.
Venous thromboembolism (VTE) is a
condition in which a blood clot forms
most often in the deep veins of the
leg, groin or arm (known as deep vein
thrombosis, DVT) and travels in the
circulation, lodging in the lungs
(known as pulmonary embolism, PE).
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PULMONARY EMBOLISM
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Reduced Blood Flow
Venous stasis occurs when blood flow is reduced, when veins are dilated, and when skeletal muscle contraction is
reduced.
Damage
Damage to the intimal lining of blood vessels creates a site for clot formation
Phlebitis
Formation of a Thrombus frequently accompanies phlebitis, which is an inflammation of the vein walls.
Platelet Aggregates
Venous thrombi are aggregrates off platelets attached to the vein wall that have tail-like Appendage containing
fibrin, whiteblood cells, and many red blood cells
Tail
The “tail” can grow or can propagate in the direction of the blood flow as successive layers of the thrombus form
Fragmentation
Fragmentation of the thrombus can occur spontaneously as it dissolves naturally, or it can occur with an elevated
venous pressure
Recanalization
After an acute episode of DVT, recanalization or reestablishment of the lumen of the vessel typically occurs
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Asymmetrical
edema
Asssymetrical calf
swelling
Localized pain in
the calf
Redness or
noticeable
discoloration
Warmth
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DOPPLER COMPUTED
ULTRASOUND TOMOGRAPHY
The tip of the Doppler Computed tomography
transducer is provides
positioned at a 45- to cross-sectional images
60-degree angle over of soft tissue and
the expected location visualizes the area of
of the artery and volume changes to an
angled slowly to extremity and the
identify arterial blood compartment where
flow. changes take place
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Strong Risk
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Moderate Risk
Age (60+)
Cancer/chemotherapy
Trauma
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Other Factors
Obesity
Smoking
Alcohol consumption
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01 Anticoagulants (e.g., injectables such as heparin,
enoxaparin, or low molecular weight heparin, or
tablets such as apixaban, dabigatran and
rivaroxaban, edoxaban and warfarin)