Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects

Generic Name: Pharmacologic Class: This drug blocks the activitiy  For treatment of 1. Hypersensitivity to drug or CNS
Ketoprofen Nonsteroidal anti-inflammatory of cyclooxygenase, the enzyme symptoms of osteoarthritis other NSAIDs 1. Headache
drug (NSAID), propionic acid needed for prostaglandin and rheumatoid arthritis 2. Irritability
Trade/Brand Name: derivative synthesis. Prostaglandins, 2. History of asthma, urticaria, 3. Nervousness
Nexcede, Orudis important mediator of  For relief of mild to or allergic-type reactions to 4. Seizures
Therapeutic Class: inflammatory response, cause moderate pain aspiri, iodides, or other 5. Cerebrovascular accident
Antirheumatic, anti- local vasodilation with pain NSAIDs, including the aspirin
 For relief of pain triad (asthma, nasal polyps,
inflammatory, analgesic and swelling. By blocking CV
associated with and severe hypersensitivity
cyclooxygenase and inhibiting 1. Edema
dysmenorrhea reactions to aspirin)
Pregnancy Risk: prostaglandins, this drug 2. Hypertension
Category B (first & second reduces inflammatory 3. Myocardial infarction
3. Perioperative use in
trimesters), Category D (third symptoms and relieves pain. 4. Tachycardia
Sources: coronary artery bypass graft
trimester)
Jones & bartlett learning surgery EENT
2018 nurse’s drug handbook
Sources: 4. Pregnant women in late 1. Tinnitus
(7th ed.). (2018). Jones &
Sources: Jones & bartlett learning 2018 pregnancy (may cause 2. Vision changes
Bartlett Learning.
Jones & bartlett learning 2018 nurse’s drug handbook (7th premature closure of the
nurse’s drug handbook (7th ed.). ed.). (2018). Jones & Bartlett ductus arteriosus) GI
Kizior, R.J. & Hodgson, K.J.
(2018). Jones & Bartlett Learning. 1. Abdominal pain
(2019). Saunders nursing
Learning. 5. Tartrazine intolerance 2. Anorexia
drug handbook 2019 (27th
Kizior, R.J. & Hodgson, K.J. 3. Constipation
ed.). Elsevier. 6. Active GI bleeding
Kizior, R.J. & Hodgson, K.J. (2019). Saunders nursing drug 4. Diarrhea
(2019). Saunders nursing drug handbook 2019 (27th ed.). 5. Diverticulitis
Skidmore-Roth, L. (2019). 7. Ulcer disease
handbook 2019 (27th ed.). Elsevier. 6. Dyspepsia
Mosby’s 2019 nursing drug
Elsevier. 7. Dysphagia
reference (32nd ed.). Elsevier. Precautions
Skidmore-Roth, L. (2019). 8. Elevated liver enzymes
Skidmore-Roth, L. (2019). Mosby’s 2019 nursing drug Use with extreme caution in 9. Flatulence
Vallerand, A.H. & Sanoski, patients with:
Mosby’s 2019 nursing drug reference (32nd ed.). Elsevier. 10. Gastritis
C.A. (2019). Davis’s drug
reference (32nd ed.). Elsevier. 11. Gastroenteritis
guide for nurses (16th ed.). 1. History of GI bleeding or
Vallerand, A.H. & Sanoski, 12. Gastroesophageal reflux
F.A. Davis Company. ulcer disease
Vallerand, A.H. & Sanoski, C.A. (2019). Davis’s drug disease
C.A. (2019). Davis’s drug guide guide for nurses (16th ed.). F.A. 2. Hypertension 13. GI bleeding and ulceration
for nurses (16th ed.). F.A. Davis Davis Company. 14. Hiatal hernia
Company. 3. Advanced age (elderly 15. Indigestion
patients) 16. Melena
17. Nausea
4. Long-term ketoprofen 18. Perforation of intestine or
therapy stomach
19. Stomatitis
20. Vomiting
Sources:
Jones & bartlett learning Hepatic
2018 nurse’s drug handbook 1. Hepatic failure
(7th ed.). (2018). Jones &
Bartlett Learning. GU
1. Acute renal failure
Kizior, R.J. & Hodgson, K.J. 2. Decreased urine output
(2019). Saunders nursing drug
handbook 2019 (27th ed.). HEME
Elsevier. 1. Agranulocytosis
2. Anemia
Skidmore-Roth, L. (2019). 3. Easy bruising
Mosby’s 2019 nursing drug 4. Hemolytic anemia
reference (32nd ed.). Elsevier. 5. Leukopenia
6. Neutropenia
Vallerand, A.H. & Sanoski, 7. Pancytopenia
C.A. (2019). Davis’s drug 8. Thrombocytopenia
guide for nurses (16th ed.).
F.A. Davis Company. RESP
1. Asthma
2. Respiratory depression

Skin
1. Erythema multiforme
2. Stevens-Johnson syndrome
3. Toxic epidermal necrolysis
4. Rash

Other
1. Anaphylaxis
2. Angioedema
3. Rapid weight gain

Sources:
Jones & bartlett learning
2018 nurse’s drug handbook
(7th ed.). (2018). Jones &
Bartlett Learning.

Kizior, R.J. & Hodgson, K.J.

Skidmore-Roth, L. (2019).
Mosby’s 2019 nursing drug
reference (32nd ed.). Elsevier.

Vallerand, A.H. & Sanoski,