Material Balance Problems

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FUNDAMENTALS IN MATERIAL BALANCE

1. The problem statement goes as shown here the heart is divided into two sides each with two
chambers blood enter the left atrium from the pulmonary veins and brings to the left ventricle where
the blood is pumped out at the average rate of 70 beats per minute the stroke volume which is defined
as the volume or blood discharged from the ventricle to the aorta is 70 ML for each contraction.
Assuming that more reaction with blood occurs in the heart and the heart chamber do now accumulate
blood determine the inlet and output mass flow rates for the left side of the heart you can assume the
density of the blood to the 1 gram per ML.

MATERIAL BALANCE CALCULATIONS FOR SINGLE UNITS WITHOUT REACTIONS- PART 1


2. A stream of growth medium containing 60% glucose and 40%growth factor A is flowing at 500 grams per
hour and is being divided into two feeds streams for different cell cultures. One fourth of the growth medium
was sent to fermenter 1and the rest was sent to fermenter 2. What is the flow rates of glucose and growth
factor A in the feed streams for the two fermenters?

3. Primary antibody deficiencies are treated with subcutaneous immunoglobulin replacement therapy this SC
IG products contains 10% IG G which is a type of immunoglobulin and 5% sorbitol and the rest is water. This
mixture can be prepared by mixing a concentrated IG solution which contains 50% IGG and rest water or
concentrated sorbitol solution containing 40% sorbitol and rest water and pure water in the correct ratio. How
much A, B and C which are the three different solution that needs to be mixed to produce 10 liter of SC IG
products. You can assume that the density for all the solutions = 1 grams per centimeters cube.

4. Unsweetened condensed milk is the shelf-stable canned milk product. If 100 kilogram of fresh milk
containing 87% water and the rest milk solids is condensed using an evaporator to remove 60% water from the
fresh milk, calculate.

The mass of water evaporated:

The final mass and composition of condensed milk produced:

PART 2

1. The problem statement says 200 liters per minute of aqueous solution containing 10 grams per liter of
streptomycin is contacted by 10 liters per minute of organic solvent. The exit aqueous solution contain 0.2
grams per liter streptomycin determine the mass fraction of streptomycin in the exit organic solvent assuming
that streptomycin is the only component that transfers that assume density of aqua solution is 1 gram per
centimeters cube and the density per organic solvent is 0.6 grams per centimeter cube.

2. the experiment on certain growth of certain organisms required and environment of humid air enriched in
oxygen input streams are fed in an evaporation chamber to produce an output stream with the desired
composition

A. liquid water which is fed at a rate of 20 centimeter cube per minute

B. the second stream contains air per 21% oxygen and the rest is nitrogen.

C. And we have the third stream which is pure oxygen with the molar flow rate of one fifth of the molar flow
rate of the stream B.

The output gas is the analyzed and is found to contain 1.5 mole percent water you are asked to first draw and
label the flowchart for the process and calculate all the unknowns stream variable
PART 3

1. Hard liquor is produced by distillation of liquid drinks made with grains fruits or vegetables that have
already gone through organic fermentation. To increase the alcohol content the fermentation product
containing 5% ethanol (E) and 95% water (W) by mass is fed to a distillation column a products stream
leaving the top of the column contains 20 mole % ethanol and the bottom product stream contains 5% of
the ethanol fed to the column the flow of the feed stream is 2000 kilogram per hour. Determine the mass
flow of the overhead product stream and the mass flow rate and the composition of the bottoms of the
product.
2.  a tank holds the 10000 kilograms of the saturated solution of NA2CO3 at 30 degree Celsius you want to
crystallize from this solution 3000 kilograms of NA2CO3 10H2Owithout any accompanying water to what
temperature must the system be cooled.

PART 4
1. A fermentation containing Streptomyces kanamyceticus cells is filtered using a continuous rotary vacuum
filters 120 kilograms per hour slurry is fed to the filter 1 kilogram slurry contains 60 grams of cell solid to
improve the filtration rates particle of diatomaceous earth filter aid are added at a rate of 10 kilograms
per hour. The concentration of kanamycin in the slurry is 0.05% by weight liquid filter is collected at a rate
of 112 kilograms per hour the concentration of kanamycin in the filtrate is 0.05% filter cake containing
cells and filter aid is continuously removed from the filter cloth.
What is the percentage of liquid in the filter cake?
if the concentration of kanamycin in the filter cake liquid is the same as that in the filtrate how much
kanamycin is absorbed as the kilogram of filter aid?

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