Pharmacology Reviewer
Pharmacology Reviewer
Pharmacology Reviewer
d. Medications taken by a client are part of a. Severe burning pain for a few
every nursing assessment. minutes following application.
b. Possible severe metabolic alkalosis
A 25-year-old woman is in her fifth month with continued use.
of pregnancy. She has been taking 20 units c. Black discoloration of everything
of NPH insulin for diabetes mellitus daily that comes in contact with this drug.
for six years. Her diabetes has been well d. Chilling due to evaporation of
controlled with this dosage. She has been solution from the moistened
coming for routine prenatal visits, during dressings.
which diabetic teaching has been
implemented. Which of the following Ms.Clark has hyperthyroidism and is
statements indicates that the woman scheduled for a thyroidectomy. The
understands the teaching regarding her physician has ordered Lugol’s solution for
insulin needs during her pregnancy? the client. The nurse understands that the
primary reason for giving Lugol’s solution c. Theophylline toxicity
preoperatively is to: d. Ineffective theophylline
a. Decrease the risk of agranulocytosis The client at highest risk for nephrotoxicity
postoperatively. with aminoglycoside use is a:
b. Prevent tetany while the client is
a. Male with a creatinine of 1.7 and
under general anesthesia.
BUN of 52 on a 10-day regimen.
c. Reduce the size and vascularity of
b. Female with BUN of 12 and
the thyroid and prevent hemorrhage.
creatinine of 0.8
d. Potentiate the effect of the other
c. Female with past history of cystitis
preoperative medication so less
on 5 days of therapy.
medicine can be given while the
d. Male with history of kidney stones
client is under anesthesia.
on 8 days of therapy.
A two-year-old child with congestive heart
When assessing clients for evidence of a
failure has been receiving digoxin for one
penicillin allergy, which of the following
week. The nurse needs to recognize that an
symptoms may not be considered to be a
early sign of digitalis toxicity is:
true hypersensitivity reaction?
a. Bradypnea
a. Wheezing
b. Failure to thrive
b. Nausea
c. Tachycardia
c. Urticaria
d. Vomiting
d. Angioneurotic edema
Mr. Bates is admitted to the surgical ICU
All of the following symptoms are evidence
following left adrenalectomy. He is sleepy
of a superinfection except:
but easily aroused. An IV containing
hydrocortisone is running. The nurse a. White oral plaques
planning care for Mr. Bates knows it is b. Creamy vaginal discharge
essential to include which of the following c. Skin rash
nursing interventions at this time? d. Darkened tongue
a. Monitor blood glucose levels every Which of the following statements
shift to detect the development of is true when educating clients about
hypo- or hyperglycemia. penicillin therapy?
b. Keep flat on back with minimal
movement to reduce the risk of a. The client must take the medication
hemorrhage following surgery. at evenly spaced intervals.
c. Administer hydrocortisone until vital b. The client may save leftover
signs stabilize, then discontinue the medication for a future illness.
IV. c. If signs of an allergic reaction,
d. Teach Mr. Bates how to care for his
continue the medication and notify
the physician.
wound since he is at high risk for
developing postoperative infection. d. Clients taking oral contraceptives
must be cautioned to use an alternate
Corinne is experiencing diarrhea after form of birth control while being
consuming her prescribed antibiotics for the treated with penicillin.
whole week. This is because:
Antonietta is taking antitubercular,
a. The drugs render food indigestible. the most common adverse effect she may be
b. Gastric flora is disturbed. experiencing is:
c. Fluid is added into the intestine.
d. Normal intestinal bacteria are a. Red-orange discoloration of urine
destroyed. b. Hypersensitivity
c. Hepatotoxicity
When a client with chronic obstructive d. CHF
pulmonary disease is taking theophylline
also receives ciprofloxacin (Cipro), which of In treatment of tuberculosis, the therapeutic
the following interactions would occur? rationale for combination drug therapy is to:
Mrs. Jane Gately has been dealing with A nurse is preparing the client’s morning
uterine cancer for several months. Pain NPH insulin dose and notices a clumpy
management is the primary focus of her precipitate inside the insulin vial. The nurse
should:
current admission to your oncology unit. Her
vital signs on admission are BP 110/64, a. Draw up and administer the dose.
pulse 78, respirations 18, and temperature b. Shake the vial in an attempt to
99.2 F. Morphine sulfate 6mg IV, q 4 hours, disperse the clumps.
prn has been ordered. During your c. Draw the dose from a new vial.
assessment after lunch, your findings are BP d. Warm the bottle under running water
92/60, pulse 66, respirations 10, and to dissolve the clump.
temperature 98.8. Mrs. Gately is crying and
A client with histoplasmosis has an order for b. Aspercreme
ketoconazole (Nizoral). The nurse teaches c. Myoflex
the client to do which of the following while d. Acetic acid solution
taking this medication?
A nurse is providing instructions to a client
a. Take the medication on an empty regarding quinapril hydrochloride
stomach. (Accupril). The nurse tells the client:
b. Take the medication with an antacid.
a. To take the medication with food
c. Avoid exposure to sunlight.
only.
d. Limit alcohol to 2 ounces per day.
b. To rise slowly from a lying to a
A nurse has taught a client taking a xanthine sitting position.
bronchodilator about beverages to avoid. c. To discontinue the medication if
The nurse determines that the client nausea occurs.
understands the information if the client d. That a therapeutic effect will be
chooses which of the following beverages noted immediately.
from the dietary menu?
Auranofin (Ridaura) is prescribed for a
a. Chocolate milk client with rheumatoid arthritis, and the
b. Cranberry juice nurse monitors the client for signs of an
c. Coffee adverse effect related to the medication.
d. Cola Which of the following indicates an adverse
effect?
A client who is taking famotidine (Pepcid)
asks the home care nurse what would be the a. Nausea
best medication to take for a headache. The b. Diarrhea
nurse tells the client that it would be best to c. Anorexia
take: d. Proteinuria
a. aspirin (acetylsalicylic acid, ASA) A client has been taking benzonatate
b. ibuprofen (Motrin) (Tessalon) as ordered. The nurse tells the
c. acetaminophen (Tylenol) client that this medication should do which
d. naproxen (Naprosyn) of the following?
A nurse is planning dietary counseling for a. Take away nausea and vomiting.
the client taking triamterene (Dyrenium). b. Calm the persistent cough.
The nurse plans to include which of the c. Decrease anxiety level.
following in a list of foods that are d. Increase comfort level.
acceptable?
During surgery, there is an increased
a. Baked potato potential for arrhythmias when
b. Bananas catecholamines are given with:
c. Oranges
a. halothane (Fluothane)
d. Pears canned in water
b. digoxin (Lanoxin)
A client with advanced cirrhosis of the liver c. bupivacaine (Marcaine)
is not tolerating protein well, as evidenced d. lidocaine (Xylocaine)
by abnormal laboratory values. The nurse
General anesthetics potentiate the effects of
anticipates that which of the following
which of the following drugs?
medications will be prescribed for the
client? a. Depolarizing agents
b. Skeletal muscle relaxants
a. lactulose (Chronulac)
c. Volatile liquids
b. ethacrynic acid (Edecrin)
d. Inhalation anesthetics
c. folic acid (Folvite)
d. thiamine (Vitamin B1) The most dangerous metabolic side effect of
general anesthesia that can occur during
A female client tells the clinic nurse that her
surgery is:
skin is very dry and irritated. Which product
would the nurse suggest that the client apply a. Hyperglycemia
to the dry skin? b. Hyperthermia
c. Hypoglycemia
a. Glycerin emollient
d. Hypothermia d. Paralysis
Mr. Baltazar will be undergoing surgery A client received lidocaine viscous before a
with general anesthesia. The client should be gastroscopy was performed. Following the
given which of the following instructions procedure, the nurse places a priority on
preoperatively? what assessment?
a. Eat a big breakfast a. Return of the gag reflex
b. Expect to be incontinent of urine b. Ability to urinate
postoperatively c. Abdominal pain
c. Double your medication doses d. Ability to stand
d. Expect nausea, vomiting, shivering,
The nurse observes a co-worker preparing to
and pain postoperatively
administer a solution of lidocaine and
Geneva is reviewing for her upcoming quiz epinephrine to a client with multiple
in Pharmacology. She should be aware that premature ventricular contractions. The
local and regional anesthesia act by: appropriate action by the nurse is to:
a. Inhibiting depolarization. a. Offer to monitor the client's heart
b. Increasing depolarization. rhythm.
c. Producing a semiconscious state. b. Notify the supervisor of the error.
d. Inhibiting motor movement. c. Do nothing; the drug choice is
correct.
Which of the following statements about
d. Prevent the administration and give a
shivering is correct?
plain lidocaine solution.
a. Shivering is a response controlled by
During induction of anesthesia, the nurse
the brainstem.
notes the client becomes hyperactive and
b. Shivering can occur in the absence of
physically resists the treatment. The nurse
hypothermia.
concludes what interventions are needed?
c. Shivering is effectively treated with
small doses of naloxone. a. Anesthesia must be discontinued.
d. Shivering is an uncomfortable, b. An intravenous drug will be given to
though harmless, effect of calm the client.
anesthesia. c. Anesthesia must be continued
d. The surgery will need to be
Early signs and symptoms of local
rescheduled.
anesthetic toxicity include all but one of the
following. Indicate the exception: The nurse receives the client in the
postanesthesia care unit (PACU) following a
a. Tinnitus
procedure requiring general anesthesia.
b. Perioral numbness
The most important assessment made by the
c. Dizziness
nurse relates to the client’s:
d. Hypertension
a. Level of consciousness.
A preoperative patient receives atropine
b. Pain.
before induction of anesthesia. The nurse
c. Vital signs.
caring for this patient understands that this
d. Respiratory status
agent is used to prevent:
Nurse Gretchen is discussing the use of
a. Anxiety.
cocaine as a local anesthetic with a nursing
b. Bradycardia.
student. Which statement by the student
c. Dry mouth.
indicates understanding of this agent?
d. Hypertension.
a. "Anesthetic effects develop slowly
The nurse teaching a client who will receive
and persist for several hours."
thiopental (Pentothal) as an anesthetic
b. "Cocaine is a local anesthetic
explains what common adverse effects
administered by injection."
might occur?
c. "Vasoconstrictors should not be used
a. Headache as adjunct agents with this drug."
b. Emergence delirium d. "When abused, cocaine causes
c. Nausea and vomiting physical dependence."
The client asks the nurse to explain the b. Codeine causes diarrhea, so the
action of infiltration anesthesia. The nurse’s client must take an additional drug to
response is based on the knowledge that prevent this.
infiltration anesthesia: c. Codeine is very constipating.
d. Codeine is antitussive in high doses.
a. Is applied only to mucous
membranes to provide local A client went to a health care facility to ask
anesthesia. for instructions regarding how to administer
b. Blocks a specific group of nerves in ophthalmic medications. The nurse correctly
tissues close to the operative area. instructs the client to?
c. Blocks sensation to an entire limb, or
a. Gently allow the tip of the optic
a large area of the face.
bottle to touch with the conjunctival
d. Produces numbing to large, regional
sac.
areas such as the lower abdomen and
b. Apply gentle pressure with a clean
legs.
tissue to the nasolacrimal duct for 30
All narcotics, regardless of their origin, seconds after the administration.
reduce pain by: c. Blink quickly to stimulate tearing
after the administration.
a. Stimulating opiate receptors.
d. Blow the nose to stimulate faster
b. Promoting the release of excitatory
absorption.
transmitters.
c. Releasing large quantities of The client is receiving an eye ointment and
endorphin. an eye drop. The nurse instructs the client
d. Blocking the mu receptors. to?
In addition to analgesia, narcotic effects a. Administer the eye ointment first,
include: followed by the eye drop.
b. Administer the eye drop first,
a. Euphoria, diarrhea, increased
followed by the eye ointment.
respirations
c. Administer the eye ointment, wait
b. Euphoria, miosis, nausea and
for 5 minutes then administer the eye
vomiting
drop.
c. Respiratory depression, increased
d. Administer the eye drop, wait for 10
blood pressure
minutes then administer the eye
d. Dependence, seizures, muscle
ointment.
spasms
The nurse is preparing to administer
The half-life of morphine is:
cyclopentolate (Cyclogyl) who will undergo
a. 4 to 6 hours a corneal surgery. The nurse administers the
b. 2 to 4 hours medication, knowing that the purpose of this
c. 6 to 8 hours eye drop is to?
d. 30 minutes to 1 hour
a. Dilate the pupil of the operative eye.
Which of the following statements about b. Constrict the pupil of the operative
morphine is correct? eye.
c. Reduces intraocular pressure.
a. Morphine is contraindicated in pain d. Lubricate the operative eye.
relief caused by head injury.
b. Morphine's withdrawal symptoms A client with glaucoma is receiving
cannot be relieved by methadone. betaxolol hydrochloride (Betoptic) eye
c. Morphine is most effective by drops. Which of the following interventions
parenteral administration. will the nurse likely do before the
d. Morphine quickly enters all body administration?
tissues.
a. Assessing orientation.
When administering codeine, the nurse b. Assessing peripheral pulses.
should be aware that: c. Monitor blood sugar level.
d. Monitor pulse rate.
a. Codeine produces more sedation
than other opiates. A miotic medication has been given to a
patient with glaucoma. The nurse tells the
client that the purpose of this medication is A nurse is providing instructions to a client
to? with an impacted cerumen who is prescribed
with Carbamide peroxide (Debrox). Which
a. It blocks the responses that are sent
of the following teachings made by the nurse
to the eye muscles.
indicates further research?
b. It will relax the eye muscles and
decrease blurring of vision. a. Do not touch the dropper tip or let it
c. It will constrict the eye to reduce touch your ear or any other surface.
intraocular pressure. b. Lie on your side or tilt the affected
d. It will dilate the eye to reduce ear upward. Hold the dropper
intraocular pressure. directly over the ear and place 5 to
10 drops into the ear canal.
A client went to a health care facility with a
c. Hold the earlobe up and back.
complaint of difficulty opening the eyelid
d. Use a cold preparation of the
because of pain. The physician diagnosed
medication.
the client with keratitis and is prescribed
with an eye lubricant. Which of the
following medicines should the nurse expect
PHARMACOLOGY EXAM 3
to administer?
An infection in a central venous access
a. hydroxypropyl methylcellulose
device is not eliminated by giving antibiotics
(Lacril).
through the catheter. How would bacterial
b. pilocarpine hydrochloride (Isopto
glycocalyx contribute to this?
Carpine).
c. timolol maleate (Timoptic). a. It protects the bacteria from
d. apraclonidine (Lopidine). antibiotic and immunologic
destruction.
The nurse is monitoring a client with
b. Glycocalyx neutralizes the antibiotic
glaucoma. Which of the following drugs, if
rendering it ineffective.
prescribed for the client, would the nurse
c. It competes with the antibiotic for
question?
binding sites on the microbe.
a. metipranolol (Optipranolol). d. Glycocalyx provides nutrients for
b. brimonidine (Alphagan P). microbial growth.
c. dorzolamide (Trusopt).
Central venous access devices are beneficial
d. atropine (Isopto Atropine).
in pediatric therapy because:
The nurse prepares an adult client for an ear
a. They don’t frighten children.
irrigation as ordered by the physician.
b. Use of the arms is not restricted.
Which of the following procedures was
c. They cannot be dislodged.
correctly performed by the nurse?
d. They are difficult to see.
a. Position the client with the affected
How can central venous access devices
side up after the irrigation.
(CVADs) be of value in a patient receiving
b. Pull the pinna down and back.
chemotherapy who has stomatitis and severe
c. Warm the irrigating solution to 98º
diarrhea?
Fahrenheit.
d. Directs a slow steady current of a. The chemotherapy can be rapidly
irrigating solution into the eardrum. completed allowing the stomatitis
and diarrhea to resolve.
The nurse is reviewing the drug list of an
b. Crystalloid can be administered to
elderly client who is taking a lot of
prevent dehydration.
medications given by different health care
c. Concentrated hyperalimentation fluid
provider. The client reports that “Lately,
can be administered through the
there has been roaring in my ears”. Which
CVAD.
medication would the nurse determine could
d. The chemotherapy dose can be
be responsible for the client’s complaint?
reduced.
a. amoxicillin (Amoxil).
Some central venous access devices
b. carvedilol (Coreg).
(CVAD) have more than one lumen. These
c. atropine sulfate (Isopto Atropine).
multi-lumen catheters:
d. aspirin (Ecotrin).
a. Have an increased risk of infiltration. What volume of air can safely be infused
b. Only work a short time because the into a patient with a central venous access
small-bore clots off. device (CVAD)?
c. Are beneficial to patient care but are
a. It is dependent on the patient’s
prohibitively expensive.
weight and height.
d. Allow different medications or
b. Air entering the patient through a
solutions to be administered
CVAD will follow circulation to the
simultaneously.
lungs where it will be absorbed and
Some institutions will not infuse a fat cause no problems.
emulsion, such as Intralipid, into central c. It is dependent on comorbidities such
venous access devices (CVAD) because: as asthma or chronic obstructive lung
disease.
a. Lipid residue may accumulate in the
d. None.
CVAD and occlude the catheter.
b. If the catheter clogs, there is no Kent, a new staff nurse asks her preceptor
treatment other than removal and nurse how to obtain a blood sample from a
replacement. patient with a portacath device. The
c. Lipids are necessary only in the most preceptor nurse teaches the new staff nurse:
extreme cases to prevent essential
a. The sample will be withdrawn into a
fatty acid (EFA) deficiency
syringe attached to the Portacath
d. Fat emulsions are very caustic.
needle and then placed into a
A male patient needs a percutaneously vacutainer.
inserted central catheter (PICC) for b. Portacath devices are not used to
prolonged IV therapy. He knows it can be obtain blood samples because of the
inserted without going to the operating risk of clot formation.
room. He mentions that, “at least the doctor c. The vacutainer will be attached to
won’t be wearing surgical garb, will he?” the Portacath needle to obtain a
How will the nurse answer the patient? direct sample.
d. Any needle and syringe may be
a. “You are correct. It is a minor
utilized to obtain the sample.
procedure performed on the unit and
does not necessitate surgical attire.” What is the purpose of “Tunneling”
b. “To decrease the risk of infection, (inserting the catheter 2-4 inches under the
the doctor inserting the PICC will skin) when the surgeon inserts a Hickman
wear a cap, mask, and sterile gown central catheter device?
and gloves.”
a. Increases the patient’s comfort level.
c. “It depends on the doctor’s
b. Decreases the risk of infection.
preference.”
c. Prevents the patient’s clothes from
d. “Most doctors only wear sterile
having contact with the catheter.
gloves, not a cap, mask, or sterile
d. Makes the catheter less visible to
gown.”
other people.
A male patient is to receive a percutaneously
The primary complication of a central
inserted central catheter (PICC). He asks the
venous access device (CVAD) is:
nurse whether the insertion will hurt. How
will the nurse reply? a. Thrombus formation in the vein.
b. Pain and discomfort.
a. “You will have general anesthesia so
c. Infection.
you won’t feel anything.”
d. Occlusion of the catheter as the
b. “It will be inserted rapidly, and any
result of an intra-lumen clot.
discomfort is fleeting.”
c. “The insertion site will be Nurse Blessy is doing some patient
anesthetized. Threading the catheter education related to a patient’s central
through the vein is not painful.” venous access device. Which of the
d. “You will receive sedation prior to following statements will the nurse make to
the procedure.” the patient?
a. “These types of devices are
essentially risk-free.”
b. “These devices seldom work for a. Prostate cancer.
more than a week or two b. Thyroid cancer.
necessitating replacement.” c. Renal carcinoma.
c. “The dressing should only be d. Neuroblastoma.
changed by your doctor.”
Serotonin release stimulates vomiting
d. “Heparin is instilled into the lumen
following chemotherapy. Therefore,
of the catheter to decrease the risk of
serotonin antagonists are effective in
clotting.”
preventing and treating nausea and vomiting
The chemotherapeutic DNA alkylating related to chemotherapy. An example of an
agents such as nitrogen mustards are effective serotonin antagonist antiemetic is:
effective because they:
a. ondansetron (Zofran).
a. Cross-link DNA strands with b. fluoxetine (Prozac).
covalent bonds between alkyl groups c. paroxetine (Paxil).
on the drug and guanine bases on d. sertraline (Zoloft).
DNA.
Methotrexate, the most widely used
b. Have few, if any, side effects.
antimetabolite in cancer chemotherapy does
c. Are used to treat multiple types of
not penetrate the central nervous system
cancer.
(CNS). To treat CNS disease this drug must
d. Are cell cycle-specific agents.
be administered:
Hormonal agents are used to treat some
a. Intravenously.
cancers. An example would be:
b. Subcutaneously.
a. Thyroxine to treat thyroid cancer. c. Intrathecally.
b. ACTH to treat adrenal carcinoma. d. By inhalation.
c. Estrogen antagonists to treat breast
Methotrexate is a folate antagonist. It
cancer.
inhibits enzymes required for DNA base
d. Glucagon to treat pancreatic
synthesis. To prevent harm to normal cells, a
carcinoma.
fully activated form of folic acid known as
Chemotherapeutic agents often produce a leucovorin (folinic acid; citrovorum factor)
certain degree of myelosuppression can be administered. Administration of
including leukopenia. Leukopenia does not leucovorin is known as:
present immediately but is delayed several
a. Induction therapy.
days to weeks because:
b. Consolidation therapy.
a. The patient’s hemoglobin and c. Pulse therapy.
hematocrit are normal. d. Rescue therapy.
b. Red blood cells are affected first.
A male patient is undergoing chemotherapy
c. Folic acid levels are normal.
may also be given the drug allopurinol
d. The current white cell count is not
(Zyloprim, Aloprim). Allopurinol inhibits
affected by chemotherapy.
the synthesis of uric acid. Concomitant
Currently, there is no way to prevent administration of allopurinol prevents:
myelosuppression. However, there are
a. Myelosuppression.
medications available to elicit a more rapid
b. Gout and hyperuricemia.
bone marrow recovery. An example is:
c. Pancytopenia.
a. epoetin alfa (Epogen, Procrit). d. Cancer cell growth and replication.
b. glucagon (Glucagen).
Superficial bladder cancer can be treated by
c. fenofibrate (Tricor).
direct instillation of the antineoplastic
d. lamotrigine (Lamictal).
antibiotic agent mitomycin (Mutamycin).
Estrogen antagonists are used to treat This process is termed:
estrogen hormone-dependent cancer, such as
a. Intraventricular administration.
breast carcinoma. Androgen antagonists
b. Intravesical administration.
block testosterone stimulation of androgen-
c. Intravascular administration.
dependent cancers. An example of an
d. Intrathecal administration.
androgen-dependent cancer would be:
The most common dose-limiting toxicity of cytochrome p-450 system. He has been on
chemotherapy is: this medication for 6 months. At this time,
he is started on a second medication (Drug
a. Nausea and vomiting.
B) that is an inducer of the cytochrome p-
b. Bloody stools.
450 system. You should monitor this patient
c. Myelosuppression.
for:
d. Inability to ingest food orally due to
stomatitis and mucositis. a. Increased therapeutic effects of Drug
A.
Chemotherapy induces vomiting by:
b. Increased adverse effects of Drug B.
a. Stimulating neuroreceptors in the c. Decreased therapeutic effects of
medulla. Drug A.
b. Inhibiting the release of d. Decreased therapeutic effects of
catecholamines. Drug B.
c. Autonomic instability.
Epinephrine is administered to a female
d. Irritating the gastric mucosa.
patient. The nurse should expect this agent
Myeloablation using chemotherapeutic to rapidly affect:
agents is useful in cancer treatment because:
a. Adrenergic receptors.
a. It destroys the myelocytes (muscle b. Muscarinic receptors.
cells). c. Cholinergic receptors.
b. It reduces the size of the cancer d. Nicotinic receptors.
tumor.
A nurse is providing instructions to a client
c. After surgery, it reduces the amount
receiving baclofen (Lioresal). Which of the
of chemotherapy needed.
following would be included in the teaching
d. It destroys the bone marrow prior to
plan?
transplant.
a. Limit fluid intake.
Anticipatory nausea and vomiting associated
b. Hold the medication if diarrhea
with chemotherapy occurs:
occurs.
a. Within the first 24 hours after c. Restrict alcohol intake.
chemotherapy. d. Notify the physician if weakness
b. 1-5 days after chemotherapy. occurs.
c. Before chemotherapy administration.
A nurse is analyzing the laboratory studies
d. While chemotherapy is being
on a client receiving dantrolene sodium
administered.
(Dantrium). Which of the following
Medications bound to protein have the laboratory tests would identify an adverse
following effect: effect associated with the use of the
medication?
a. Enhancement of drug availability.
b. Rapid distribution of the drug to a. Blood urea nitrogen
receptor sites. b. Creatinine
c. The more drug bound to protein, the c. Liver function test
less available for the desired effect. d. Triglyceride
d. Increased metabolism of the drug by
A nurse is caring for a client who is
the liver.
receiving cyclobenzaprine hydrochloride
Some drugs are excreted into bile and (Flexeril) for the treatment of muscle spasm.
delivered to the intestines. Prior to Which of the following medical conditions
elimination from the body, the drug may be is contraindicated with the use of the
absorbed. This process is known as: medication?
The nurse is caring for a client who is a. Therapeutic and toxic doses.
receiving fluorouracil (Adrucil). Which of b. Potency and efficacy.
the following symptoms would necessitate c. Subtherapeutic and toxic levels.
the nurse to immediate discontinuation of d. Side and adverse effects.
the medication? When a drug binds to a receptor to produce a
a. Palmar-plantar erythrodysesthesia. pharmacologic effect, the drug may be
b. Ataxia. called a(n):
c. Constipation. a. Antagonist
d. Insomnia. b. Agonist
c. Blocker
d. Accelerator
PHARMACOLOGY EXAM 5
The extent to which drug is absorbed and
The name selected by the original transported to target tissue is known as:
manufacturer based on the chemical structure
of the drug is the: a. Steady-state accumulation
b. Therapeutic drug levels
a. Chemical name c. Bioavailability
b. Drug name d. Distribution
c. Generic name
d. Drug name Drug distribution is affected by which of the
following?
The interaction of one drug increased by the
presence of a second drug is known as: a. Biotransformation
b. Excretion
a. Potentiation c. Protein binding
b. Addictive effects d. Lipid binding
c. Antagonism
d. Synergism An unexpected effect of the drug is known
as a(n):
a. Side effect
b. Adverse effect
c. Toxic reaction When performing an assessment to
d. Allergic reaction determine which medications can be used,
which of the following elements
As a knowledgeable nurse, you know that
is most important?
the following are part of the 10
rights except: a. Physical examination
b. Allergies
a. Right dose
c. Presence of illness
b. Right route
d. Weight
c. Right drug
d. Right room Central venous access devices are beneficial
in pediatric therapy because:
When performing an assessment about
medication, the drug history should include: a. They are difficult to see.
b. They cannot be dislodged.
a. Complete vital signs.
c. Use of the arms is not restricted.
b. Client's goal of therapy.
d. They don’t frighten children.
c. Reason for medication.
d. Administration of OTC medications. When considering the pharmacotherapeutic
effects of drugs administered to clients, the
The volume of SC medication must be no
nurse considers which property
more than:
of most importance:
a. 0.5 mL.
a. Efficacy.
b. 1.0 mL. b. Interaction with other drugs.
c. Potency
c. 1.5 mL. d. Toxicity
d. 3.0 mL. As a well-rounded health care provider, you
Which of the following muscles is a possible know that corticosteroid therapy is indicated
site for IM injections? in all of the following conditions except:
When deciding on what time of day to give Oral steroids are prescribed on a taper in
medications, the nurse pays the closest order to:
attention to the client’s habits regarding: a. Achieve optimal serum levels.
a. Eating b. Ensure drug reliability.
b. Sleeping c. Ensure compliance.
c. Elimination d. Prevent steroid withdrawal
d. Activity syndrome.
The client’s ability to take oral medications Orlando who has been taking steroids for
will be hindered by: rheumatoid arthritis over several years
presents with a compression vertebral
a. Age fracture. This fracture is due to:
b. Dental caries
c. Dysphagia a. An entirely separate condition.
d. Lifestyle b. The osteoporotic effect of long-term
steroid use.
Which of the following will determine c. Deterioration in rheumatoid arthritis.
nursing interventions for a client on d. An excessively high dose of steroids.
medication?
Tom is admitted to the emergency
a. Assessment department with an acute spinal cord injury.
b. Diagnosis Methylprednisolone is contraindicated for
c. Implementation treatment when the injury:
d. Evaluation
a. Is a high cervical lesion.
b. Occurred less than 4 hours ago.
c. Occurred less than 8 hours ago. c. On an empty stomach.
d. Occurred more than 8 hours ago. d. With meals.
Which of the following statements about Which of the following NSAIDs is used to
intravenous administration of steroids is prevent thrombosis?
true?
a. ibuprofen (Motrin)
a. Steroids administered intravenously b. ketorolac tromethamine (Toradol)
must be diluted. c. aspirin (Zorprin)
b. Steroids administered intravenously d. naproxen (Naprosyn)
can be either in diluted or undiluted
Nurse Corrine may expect to administer
form.
azathioprine (Imuran) to a transplant client
c. Steroids should be given IV push
in which of the following conditions?
only.
d. Intravenous administration of a. Prevention of chronic rejection.
steroids is contraindicated in acutely b. Prevention of acute rejection.
ill clients. c. Management of chronic rejection.
d. Treatment of acute rejection.
An appropriate nursing diagnosis for clients
who are taking NSAIDs and anticoagulants Which of the following laboratory tests
would be which of the following? should be monitored when a client is
receiving azathioprine?
a. Risk for injury related to prolonged
bleeding time, inhibition of platelet a. CBC
aggregation, and increased risk of GI b. BUN
bleeding. c. Electrolytes
b. Potential for injury related to GI d. Sedimentation rate
toxicity and decrease in bleeding
time. In a transplant client, the action of
c. Altered protection related to GI cyclosporine is to:
bleeding and increasing platelet a. Defend the body against foreign
aggregation. antigens.
d. Risk for injury related to b. Inhibit T cells in response to
thrombocytosis prolonged antigens.
prothrombin time. c. Inhibit B cell immunoglobulin.
Teaching has been adequate when a client d. Intensify the production of T
being treated with acetylsalicylic acid states: lymphocytes.
a. "I can crush the pills before I A client who is taking mycophenolate
swallow them." mofetil must follow which of the following
b. "I should take the pills with instructions?
antacids." a. Take with food.
c. "Taking the pills on an empty b. Avoid use of corticosteroid.
stomach will help absorption." c. Monitor for adverse effects.
d. "If the pills smell like vinegar, I d. Practice effective contraception.
should throw them out."
Which of the following client comments
Which of the following groups of clients demonstrates that teaching has been
are most at risk for GI bleeding from the use successful regarding cyclosporine therapy?
of NSAIDs?
a. "I need to mix the medicine in
a. Clients with dysmenorrhea. Styrofoam."
b. Clients with headaches. b. "I should take the medication on an
c. Clients with arthritis. empty stomach."
d. Clients with renal failure. c. "If I vomit I should take another
To minimize the risk of dyspnea and GI dose."
bleeding, OTC ibuprofen is given: d. "I need to be consistent about when I
take it and also monitor how much
a. IV fat is in my food."
b. With orange juice.
Antirheumatics are used to: d. Hematocrit is lowered.
a. Retard progression of joint Which of the following is the priority
deterioration. nursing diagnosis for a client undergoing
b. Encourage excretion of chemotherapy?
autoantibodies.
a. Altered nutrition
c. Directly affect the inflammatory
b. Fear
response.
c. Decreased cardiac output
d. Mediate the action of NSAIDs.
d. Anxiety
Gold compounds are contraindicated in
Which of the following contributes most to
clients with:
the debilitation of an individual during a
a. Liver dysfunction course of chemotherapy?
b. Cardiac disease
a. Diarrhea
c. Preexisting dermatitis
b. Alopecia
d. Rheumatoid arthritis
c. Constipation
Which of the following agents can be used d. Pain
in the treatment of rheumatoid arthritis,
Combination chemotherapy is used in the
Sjögren’s syndrome, and SLE?
treatment of cancer because:
a. auranofin (Ridaura)
a. Single-agent therapy produces cell
b. allopurinol (Zyloprim)
lines that are resistant.
c. sulfasalazine (Azulfidine)
b. drugs are more likely to work.
d. chloroquine (Aralen)
c. Single-agent therapy requires larger
Frequent eye examinations are doses for long remissions.
recommended in clients receiving: d. Two cancers may be present.
a. Chloroquine A pregnant client is receiving magnesium
b. Colchicine sulfate therapy for the control of
c. Penicillamine preeclampsia. A nurse discovers that the
d. gold compounds client is encountering toxicity from the
medication in which of the following
Nurse Tyra is instructing a client receiving
assessments?
probenecid (Benemid), she should cover all
of the following information except the need a. Respirations of 10 breaths per
to: minute.
b. Presence of deep tendon reflex.
a. Change in dietary habits.
c. Urine output of 25 ml/hr.
b. Increase fluid intake.
d. Serum magnesium level of 7 mEq/L.
c. Have frequent laboratory work done.
d. Recognize side effects. A student nurse was asked by the nurse
instructor to explain the procedure for the
Enrique who is under chemotherapy has the
administration of erythromycin ointment to
following CBC results: WBC 5000/mm3,
the eyes of the newborn. Which of the
RBC platelet 10,000/mm3. Which of the
following statements made by the student
following is he at risk for?
indicates a need for further research?
a. Infection
a. "I will instill the eye ointment into
b. Bleeding
each of the newborn's conjunctival
c. Angina
sacs."
d. None of the above
b. "I need to administer the eye
Lorraine who is on chemotherapy has a ointment within an hour after
history of cardiac disease. The client is at maternal delivery."
risk for cardiac complications because: c. "I will clean the newborn's eyes
before instilling the ointment."
a. White blood cells are reduced.
d. "I will flush the newborn's eyes after
b. Oxygen-carrying capacity may be instilling the ointment."
reduced.
c. Sodium levels may rise meaning Rho(D) immune globulin (RhoGAM) is
fluid overload. given to a pregnant woman after delivery
and the nurse is giving information to the of the following assessments will concern
patient about the indication of the the nurse most?
medication. The nurse determines that the
a. Blood glucose level of 280 mg/dl.
patient understands the purpose of the
b. Daily weight gain of 0.5 kg.
medication if the patient tells that it will
c. Client no longer recognizes the
protect her baby from which of the
family member.
following?
d. Client still complains of headaches.
a. Developing Pernicious anemia.
A client who is receiving edrophonium
b. Developing German Measles.
chloride suddenly is complaining of
c. Having an RH+ blood.
abdominal cramps and the nurse observes
d. Developing Rh incompatibility.
the client is experiencing increased
A pregnant woman who is having labor perspiration and salivation. The nurse makes
pains is receiving an opioid analgesic. sure the availability of which of the
Which of the following medications should following?
be ready in case a respiratory depression
a. Levodopa
occurs?
b. methylphenidate hydrochloride
a. oxycodone (Oxycontin) (Ritalin)
b. naloxone (Narcan) c. atropine sulfate (Atropine)
c. meperidine hydrochloride (Demerol) d. carbamazepine (Tegretol)
d. morphine sulfate (Roxanol)
A nurse is instructing a client regarding
Methylergonovine (Methergine) is carbidopa-levodopa (Sinemet) for the
prescribed to a patient who is having treatment of Parkinson’s disease. The nurse
postpartum bleeding. Prior to giving the tells the client which of the following
medication, the nurse contacts the physician indicates an overdose of the medication?
who prescribed the medication if which of
a. Difficulty performing a voluntary
the following condition is documented in the
movement.
patient’s chart?
b. Increased blood pressure.
a. Hypotension c. Decreased appetite.
b. Uterine atony d. Black tarry stools.
c. Ischemic heart disease
A nurse is giving dietary instructions to a
d. Acute Gastroenteritis
client receiving levodopa. Which of the
following food items should be avoided by
the client?
PHARMACOLOGY EXAM 6
a. Goat yogurt
A client with myasthenia gravis frequently
b. Whole grain cereal
complains of weakness and fatigue. The
c. Asparagus
physician plans to identify whether the client
d. Apples
is responding to an overdose of the
medication or a worsening of the disease. A Biperiden hydrochloride (Akineton) is added
tensilon test is performed. Which of the to a list of antiparkinsonian medications that
following would indicate that the client is an elderly client is taking. Which of the
experiencing an overdose of the medication? following instructions made by the nurse
that needs further learning?
a. Temporarily worsening of the
condition. a. Avoiding alcohol and caffeine.
b. Improvement of weakness and b. Using ice chips, candy or gum for
fatigue. dry mouth.
c. No change in the condition. c. Walking in the morning to have a
d. Complaints of muscle spasms. daily source of direct sunlight.
d. Eating foods rich in fiber and
A client with juvenile pilocytic astrocytoma
increase fluid intake.
who is receiving dexamethasone (Decadron)
4mg/IV every 6 hours to relieve symptoms
of right arm weakness and headache. Which
The nurse is giving instructions to a client c. 45-65 mcg/ml
receiving phenytoin (Dilantin). The nurse d. 50-90 mcg/ml
concludes that the client has a sufficient
A child was brought to the emergency room
knowledge if the client states that:
complaining of right upper quadrant
a. "Wearing a medical alert tag is not abdominal pain, nausea, and vomiting. Upon
required". the interview of the nurse to the mother, the
b. "Alcohol is permitted while taking client has been taking a long-term use of
this medication". acetaminophen. Overdosage of the
c. "I can take the medicine with milk". medication is suspected. Which of the
d. "Have the serum phenytoin level following medications should be readily
taken before giving the medication". available?
A 17-year-old client is taking phenytoin a. naltrexone (ReVia)
(Dilantin) for the treatment of seizures.
b. urea (Ureaphil)
Phenytoin blood level reveals to be 25
mcg/ml. Which of the following symptoms c. acetylcysteine (Mucomyst)
would be expected as a result of the
laboratory result? d. valproic acid (Depakene)
a. No symptoms, because the value is A client with bell’s palsy tells the nurse that
within the normal range. acetaminophen (Tylenol) is taken daily as
b. Hyperactivity. prescribed by the physician. Which
c. Tremors. laboratory value would indicate a toxicity of
d. Nystagmus. the medication?
a. 5-10 mcg/ml
b. 15-40 mcg/ml
Mannitol (Osmitrol), an osmotic diuretic, is c. Viral load test
contraindicated to which conditions? Select d. White blood cell count
all that apply.
A client with acquired immunodeficiency
a. Pulmonary edema syndrome is prescribed with zidovudine
b. Narrow-angle glaucoma (Azidothymidine). Which of the following
c. Heart failure laboratory results should the nurse monitor
d. Chemotherapy while on this medication?
e. Hyponatremia
a. Throat swab gram stain.
A client with tonic-clonic seizure is b. Complete blood count
receiving phenobarbital (Luminal) and c. Random blood sugar
valproic acid (Depakene). The nurse tells the d. Blood uric acid
client that:
The client who is human immunodeficiency
a. Valproic acid decreases virus seropositive has been taking saquinavir
phenobarbital metabolism. (Invirase). The nurse provides medication
b. Valproic acid increases instructions and advises the client to:
phenobarbital metabolism.
a. Take the medication in the morning
c. There is no interaction between the
before meals.
two.
b. Include a low-fat diet.
d. Increase the dosage of the two
c. Weight gain is expected.
medications.
d. Avoid being exposed to sunlight.
A nurse is providing instructions to a client
Stavudine (Zerit) is prescribed to a client
who is taking doxapram (Dopram). Which
with human immunodeficiency virus
of the following statements made by the
seropositive. The nurse observes which of
client needs further instructions?
the following most closely while the client is
a. "I need to take the medication before taking the medication?
meals".
a. Orientation
b. "I need to take the medication at
b. Gag reflex
bedtime".
c. Appetite
c. "I need to avoid drinking coffee".
d. Gait
d. "I will not chew or crush long acting
form of the medications". A nurse is evaluating a client who is HIV
positive who is prescribed with pentamidine
Diazepam (Valium) is prescribed to a client
(Pentam) IV for the treatment of
with alcohol withdrawal. Which of the
Pneumocystis carinii pneumonia. Which of
following statements made by the client
the following assessment after the
indicates an understanding of the treatment
administration is the most important to relay
regimen?
to the physician?
a. "This medication causes a blurring
a. Blood pressure of 100/62 mm/Hg.
of vision".
b. Redness and pain at the site of the
b. "This medication will cause a
infusion.
decreased platelet and white blood
c. Sudden sweating and hunger.
cell count in my blood".
d. Unusual taste or dryness in the
c. "I'll have my physician lower my
mouth.
dosage once I start to feel okay".
d. "Drinking grapefruit can decrease the A client is prescribed with Pentamidine
side effects with this medication". (Pentam) IV for the treatment of
Pneumocystis carinii pneumonia. Suddenly,
An HIV-positive client who has been started
the client develops a temperature of 101.5°F.
on highly active antiretroviral therapy
The nurse in charge knows that this sign
(HAART) came back for a follow-up
would mostly indicate which of the
checkup. Which of the following will be
following?
the most helpful in determining the response
to the therapy? a. An overdosage of the medication.
b. The need for an additional dosage.
a. Rapid HIV antigen test
b. Western Blot analysis
c. The client has developed another laboratory test during the treatment with this
infection. medication, except?
d. The client is experiencing the
a. Serum creatinine.
therapeutic effect of the medication.
b. Serum calcium.
While on pentamidine (Pentam) infusion c. Serum magnesium.
therapy. The nurse must anticipate doing d. Serum sodium.
which of the following?
A client is recently diagnosed with HIV and
a. Secure a 12-lead ECG. highly antiretroviral therapy is started. After
b. Observe for signs of retinal damage. the first week of therapy, the patient
c. Instruct the client on a low potassium complains of headaches, dizziness, and
diet. nightmares. Which one of the following
d. Instruct the client on limiting fluid antiretroviral drugs is most likely associated
intake. with these symptoms?
The nurse is monitoring a post-renal a. Lamivudine
transplantation client taking cyclosporine b. Efavirenz
(Neoral). The nurse observes an elevation in c. Tenofovir
one of the client’s vital signs and the client d. Saquinavir
is complaining of sweating and headache.
Sirolimus (Rapamune) is prescribed to a
Which of the following vital signs
post-renal transplantation client. Upon the
is most likely increased?
review of the chart, the nurse expects which
a. Respiratory rate of the following laboratory results?
b. Pulse rate
a. Elevated serum potassium
c. Temperature
b. Decreased cholesterol level
d. Blood pressure
c. Elevated platelet count
A nurse is doing an assessment data while d. Elevated triglyceride level
completing an admission for a patient with a
A post-kidney transplant client went to the
history of liver transplant who is receiving
health care facility to ask the nurse regarding
cyclosporine (Sandimmune), prednisone
vaccinations while on tacrolimus (Prograf) a
(Orasone), and azathioprine (Imuran).
medication used to prevent organ rejection.
Which of the following information will
Which of the following is an appropriate
give the nurse the most attention?
response of the nurse?
a. The client has a soft non-tender lump
a. "Do not skip due doses of
in the shoulder.
vaccination for this can help in your
b. An increased cholesterol level.
treatment".
c. Grade 1+ pitting edema in the feet.
b. "You can have live vaccinations
d. Swollen and pinkish gums noted.
even without the approval of the
A client is admitted to the emergency room physician".
complaining of difficulty of breathing and c. "Influenza can happen anytime, so a
upon auscultation, the nurse noted that the flu vaccine is a must."
patient has wheezes. An allergic reaction to d. "Do not receive any live vaccinations
penicillin was diagnosed. Which of the while on this treatment".
following medications should the nurse
A nurse is giving instructions to a client who
expect to administer first?
is receiving mycophenolate mofetil
a. aminophylline (Theophylline) (CellCept) and mycophenolic acid
b. albuterol (Ventolin HFA) (Myfortic) after undergoing a heart
c. methylprednisolone (Solu-Medrol) transplant. The nurse tells the client to
d. pulmicort (Budesonide) anticipate the following side effects, except?
The nurse is assigned to care for a client a. Hypersomnia
with cytomegalovirus retinitis and acquired b. Vomiting
immunodeficiency syndrome who is c. Hypertension
receiving foscarnet (Foscavir). The nurse d. Diarrhea
carefully monitors which of the following
Amikacin (Amikin) is given to a client with A nurse instructor is about to administer a
E-coli infection. The nurse advises the client vitamin K injection to a newborn. The
to report which of the following student nurse asks the instructor regarding
symptoms immediately? the purpose of the injection. The appropriate
response would be:
a. Muscle pain
b. Constipation a. "The vitamin K will protect the
c. Fatigue newborn from bleeding."
d. Hearing loss b. "The vitamin K will prevent the
occurrence of hyperbilirubinemia."
A client went to the emergency room with
c. "The vitamin K provides active
complaints of abdominal pain, nausea,
immunity."
diarrhea, and mucoid stools. Upon the
d. "The vitamin K will serve as
interview with the nurse, the client stated
protection against jaundice and
that he is taking cefixime (Suprax) for the
anemia."
treatment of urinary tract infection. The
nurse determines that the client A nurse is assigned to a patient who is
is most likely suffering from? receiving oxytocin (Pitocin) to induce labor.
The nurse terminates the oxycontin infusion
a. Crohn's disease
if which of the following is noted on the
b. Acute Gastroenteritis
assessment of the client?
c. Acute appendicitis
d. Pseudomembranous colitis a. Nausea
b. Fatigue
Amphotericin B (Fungizone) IV is given to a
c. Early decelerations of the fetal heart
client with aspergillosis, a fungal infection.
rate
In order to prevent its side effects, the nurse
d. Uterine hyperstimulation
anticipates administering which of the
following prior, except? A client in preterm labor (32 weeks) who is
dilated to 5cm has been given magnesium
a. Hydrocortisone
sulfate and the contractions have stopped. If
b. Ketoconazole
the labor can be delayed for the next 2 days,
c. Diphenhydramine
which of the following medication does the
d. Meperidine
nurse expect that will be prescribed?
A nurse is giving instructions to a client
a. fentanyl (Sublimaze)
taking ciprofloxacin (Cipro) for the
b. sufentanil (Sufenta)
treatment of gonorrhea. The nurse tells the
c. betamethasone (Celestone)
client to?
d. butorphanol tartrate (Stadol)
a. Report any history of tendon
Which of the following laboratory tests must
problems.
be monitored for pregnant patients receiving
b. Resume daily exercise such as
dexamethasone?
biking.
c. Take an antacid 30 minutes prior. a. Random blood sugar
d. Take it with a yogurt as part of the b. Serum calcium
treatment. c. Red blood cell count
d. Uric acid
Tetracycline has been prescribed for a client
with Chlamydia trachomatis infection. Patellar reflex is being monitored for
Select the side effect of the patients receiving magnesium sulfate
medication. Select all that apply. therapy. When assessing the deep tendon
reflex, which of the following grades
a. Glossitis
pertains to diminished response?
b. Tremors
a. Grade 0
c. Urinary frequency b. Grade 1
c. Grade 2
d. Discoloration of the nails d. Grade 4
e. Photosensitivity Prior giving of methylergonovine
(Methergine), what is the priority
assessment for the nurse to check which of e. Increase the flow rate of the
the following? intravenous additive solution.
a. Deep tendon reflexes
b. Urine output
c. Vaginal bleeding
d. Blood pressure
A nurse is preparing to give a lung
surfactant to a 36 weeks old baby with
respiratory distress syndrome. Which of the
following is the correct route of
administration?
a. Intradermal
b. Intratracheal
c. Intramuscular
d. Intravenous
A nurse is preparing to administer a Rubella
vaccine to a client prior to home discharge.
Which of the following is not true regarding
this vaccine?
a. Pain, redness, swelling, or a lump are
some of the adverse reactions.
b. Given intramuscularly in the lateral
aspect of the middle third of the
vastus lateralis muscle.
c. The need to use contraception after
immunization.
d. Contraindicated in a client with an
allergy to duck eggs.
A nurse is preparing dinoprostone (Cervidil)
for a client to induce labor. Which of the
following nursing intervention must be
questioned?
a. Have the client hold void before
administration.
b. Place the client in a side-lying
position for 30 to 60 minutes after
the administration.
c. Monitor maternal vital signs.
d. Have the client void before
administration.
A nurse caring for a patient receiving
oxytocin therapy suddenly is experiencing
hypertonic contractions. Which of the
following priority nursing actions should the
nurse do? Select all that apply.
a. The nurse leaves the client to ask for
help.
b. Administer oxygen at 8 to 10 liters
per minute.
c. Stop the oxytocin infusion.
d. Place the client in the supine
position.