CANDIDIASIS (moniliasis or yeast infection) - Antifungal medicine inserted in the vagina

- Fluconazole po
- Caused by the organism Candida albicans, which has several
- Clotrimazole cream
strains of different virulence. Candida organisms are part of
- Miconazole
the normal vaginal environment in up to 50% of women
- Terconazole cream
(Porth & Matfin, 2009), causing problems only when they
multiply rapidly.
- Uncircumcised men may develop a yeast infection over the
Diagnostic exams
glans penis, manifested by itching and dysuria.
- Candida normally lives on skin and inside the body, such as - Physical examination
the mouth, throat, gut, and vagina, without causing o The doctor will check if vulvar and vaginal
problems. Candida can cause infections if it grows out of erythema, excoriations, thick white adherent
control or if it enters deep into the body. For example, it can discharge, and swelling are present.
cause infections in the bloodstream or internal organs like - Fungal culture test
the kidney, heart, or brain. o Healthcare providers usually diagnose vaginal
The manifestations include: candidiasis by taking a small sample of vaginal
discharge. They examine the sample under a
- Odorless thick cheesy vaginal discharge, often accompanied microscope in the medical office or send it to a
by itching and irritation of the vulva and vagina laboratory for a fungal culture.
- dysuria, and dyspareunia.
- Pain during sexual intercourse

Assessment

- Healthcare practitioners relies on physical examinations,

symptoms, medical history and laboratory tests

Treatment

- Short-course topical formulations (i.e., single dose and

regimens of 1–3 days) effectively treat uncomplicated VVC.
Treatment with azoles results in relief of symptoms and
negative cultures in 80%–90% of patients who complete
therapy.
 Saint Paul University Philippines
Tuguegarao City, Cagayan 3500
School of Nursing and Allied Health Sciences
COLLEGE OF NURSING

MECHANISM OF SIDE EFFECTS/ NURSING

DRUG CLASSIFICATION INDICATION CONTRAINDICATIONS
ACTION ADVERSE EFFECTS RESPONSIBILITIES
Generic Name: Antifungal Inhibits fungal Oropharyngeal Contraindicated in patients Side Effects: - Tell patient to
Fluconazole PO cytochrome P-450 candidiasis hypersensitive to drug and - Headache. Rest and take drug as
(responsible for breast-feeding patients. drink plenty of directed, even
Brand Name: fungal sterol Esophageal Use cautiously in patients fluids. - after he feels
Diflucan synthesis); weakens. candidiasis hypersensitive to other - Stomach pain. Try to better.
antifungal azole rest and relax. ... - Instruct patient to
Fungal cell walls. Vulvovaginal compounds. - Diarrhoea. Drink lots report adverse
candidiasis of fluids, such as reactions
water or squash, to - promptly
Systemic candidiasis avoid dehydration. ...
- Feeling or being sick
Cryptococcal (nausea or vomiting)
meningitis Stick to simple meals
and do not eat rich or
To prevent spicy food. ...
candidiasis in bone - Rash.
marrow
transplant and cancer Adverse Effects:
patients CNS: headache,
dizziness.
To suppress relapse GI: nausea, vomiting,
of cryptococcal abdominal pain,
meningitis in patients diarrhea, dyspepsia, taste
with AIDS perversion.
Hematologic:
leukopenia,
thrombocytopenia.
Skin: rash.
Other: anaphylaxis
 MECHANISM OF SIDE EFFECTS/ NURSING
DRUG CLASSIFICATION INDICATION CONTRAINDICATIONS
ACTION ADVERSE EFFECTS RESPONSIBILITIES
Generic name: Antifungal Fungistatic or Superficial fungal Contraindicated in patients Side effect: Consult prescriber
Clotrimazole fungicidal, infections (tinea hypersensitive to drug. before using topical
depending on corporis, tinea cruris, Adverse effect: preparations in children
Brand name: level. tinea pedis, tinea Contraindicated for GI: lower abdominal younger than age.
Alters fungal cell- versicolor, ophthalmic use. cramps, nausea and
wall permeability candidiasis) vomiting with lozenges. Don’t use troches in
and produces GU: mild vaginal burning or children younger than
osmotic instability. Vulvovaginal irritation, age
candidiasis urinary frequency.
Skin: erythema, blistering, don’t use vaginal
Oropharyngeal burning, edema, preparations in children
candidiasis general irritation, peeling, younger than age 12.
pruritus, skin
To prevent fissures, stinging, urticaria. Watch for irritation or
oropharyngeal sensitivity; stop if
candidiasis in irritation occurs and
patients notify prescriber.
immunocompromise
d Improvement usually
by chemotherapy, occurs within 1 week; if
radiotherapy, or no improvement is seen
corticosteroid therapy within 4 weeks, review
in the treatment of diagnosis.
leukemia, solid
tumors, or renal
transplantation