Safety data sheet

acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439 date of compilation: 2015-12-04

Version: 3.0 en Revision: 2022-05-25
Replaces version of: 2020-03-19
Version: (2)

SECTION 1: Identification of the substance/mixture and of the company/

undertaking
1.1 Product identifier
Identification of the substance 1-Octanol ≥99 %, for synthesis
Article number 4439
EC number 203-917-6
CAS number 111-87-5
1.2 Relevant identified uses of the substance or mixture and uses advised against
Relevant identified uses: Laboratory chemical
Laboratory and analytical use
Uses advised against: Do not use for products which come into contact
with foodstuffs. Do not use for private purposes
(household).
1.3 Details of the supplier of the safety data sheet
Carl Roth GmbH + Co KG
Schoemperlenstr. 3-5
D-76185 Karlsruhe
Germany

Telephone:+49 (0) 721 - 56 06 0

Telefax: +49 (0) 721 - 56 06 149
e-mail: sicherheit@carlroth.de
Website: www.carlroth.de
Competent person responsible for the safety data :Department Health, Safety and Environment
sheet:
e-mail (competent person): sicherheit@carlroth.de
1.4 Emergency telephone number
Name Street Postal Telephone Website
code/city

National Poisons Information Dudley Rd B187QH 844 892 0111

Service Birmingham
City Hospital

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture
Classification acc. to GHS
Section Hazard class Cat- Hazard class and Hazard
egory category statement

3.3 Serious eye damage/eye irritation 2 Eye Irrit. 2 H319

4.1C Hazardous to the aquatic environment - chronic hazard 3 Aquatic Chronic 3 H412

For full text of abbreviations: see SECTION 16

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Safety data sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439

The most important adverse physicochemical, human health and environmental effects
Spillage and fire water can cause pollution of watercourses.
2.2 Label elements
Labelling

Signal word Warning

Pictograms

GHS07

Hazard statements
H319 Causes serious eye irritation
H412 Harmful to aquatic life with long lasting effects

Precautionary statements
Precautionary statements - prevention
P273 Avoid release to the environment
P280 Wear protective gloves/eye protection
Precautionary statements - response
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact
lenses, if present and easy to do. Continue rinsing
P337+P313 If eye irritation persists: Get medical advice/attention
2.3 Other hazards
This material is combustible, but will not ignite readily.
Results of PBT and vPvB assessment
According to the results of its assessment, this substance is not a PBT or a vPvB.

SECTION 3: Composition/information on ingredients

3.1 Substances
Name of substance 1-Octanol
Molecular formula C₈H₁₈O
Molar mass 130,2 g/mol

CAS No 111-87-5
EC No 203-917-6

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Safety data sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439

SECTION 4: First aid measures

4.1 Description of first aid measures

General notes
Take off contaminated clothing.
Following inhalation
Provide fresh air. In all cases of doubt, or when symptoms persist, seek medical advice.
Following skin contact
Rinse skin with water/shower.
Following eye contact
Irrigate copiously with clean, fresh water for at least 10 minutes, holding the eyelids apart. In case of
eye irritation consult an ophthalmologist.
Following ingestion
Rinse mouth. Call a doctor if you feel unwell.
4.2 Most important symptoms and effects, both acute and delayed
Irritation, Headache, Vertigo, Dizziness, Fatigue, Narcosis
4.3 Indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media

co-ordinate firefighting measures to the fire surroundings
water spray, dry extinguishing powder, BC-powder, carbon dioxide (CO₂)
Unsuitable extinguishing media
water jet
5.2 Special hazards arising from the substance or mixture
Combustible. Vapours are heavier than air, spread along floors and form explosive mixtures with air.
Hazardous combustion products
In case of fire may be liberated: Carbon monoxide (CO), Carbon dioxide (CO₂)
5.3 Advice for firefighters
In case of fire and/or explosion do not breathe fumes. Do not allow firefighting water to enter drains
or water courses. Fight fire with normal precautions from a reasonable distance. Wear self-contained
breathing apparatus.

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Safety data sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

For non-emergency personnel

Avoid contact with skin, eyes and clothes. Do not breathe vapour/spray.
6.2 Environmental precautions
Keep away from drains, surface and ground water. Retain contaminated washing water and dispose
of it.
6.3 Methods and material for containment and cleaning up
Advice on how to contain a spill
Covering of drains.
Advice on how to clean up a spill
Absorb with liquid-binding material (sand, diatomaceous earth, acid- or universal binding agents).
Other information relating to spills and releases
Place in appropriate containers for disposal. Ventilate affected area.
6.4 Reference to other sections
Hazardous combustion products: see section 5. Personal protective equipment: see section 8. Incom-
patible materials: see section 10. Disposal considerations: see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling
Provision of sufficient ventilation.
Measures to prevent fire as well as aerosol and dust generation

Keep away from sources of ignition - No smoking.

Advice on general occupational hygiene
Wash hands before breaks and after work. Keep away from food, drink and animal feedingstuffs.
7.2 Conditions for safe storage, including any incompatibilities
Keep container tightly closed.
Incompatible substances or mixtures
Observe hints for combined storage.
Consideration of other advice:
Specific designs for storage rooms or vessels
Recommended storage temperature: 15 – 25 °C
7.3 Specific end use(s)
No information available.

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Safety data sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439

SECTION 8: Exposure controls/personal protection

8.1 Control parameters
National limit values
Occupational exposure limit values (Workplace Exposure Limits)
This information is not available.
Environmental values

Relevant PNECs and other threshold levels

End- Threshold Organism Environmental com- Exposure time

point level partment

PNEC 0,2 mg/l aquatic organisms freshwater short-term (single instance)

PNEC 0,02 mg/l aquatic organisms marine water short-term (single instance)

PNEC 55,5 mg/l aquatic organisms sewage treatment plant short-term (single instance)
(STP)

PNEC 2,1 mg/kg aquatic organisms freshwater sediment short-term (single instance)

PNEC 0,21 mg/kg aquatic organisms marine sediment short-term (single instance)

PNEC 1,6 mg/kg terrestrial organisms soil short-term (single instance)

8.2 Exposure controls

Individual protection measures (personal protective equipment)
Eye/face protection

Use safety goggle with side protection.

Skin protection

• hand protection
Wear suitable gloves. Chemical protection gloves are suitable, which are tested according to EN 374.
For special purposes, it is recommended to check the resistance to chemicals of the protective gloves
mentioned above together with the supplier of these gloves. The times are approximate values from
measurements at 22 ° C and permanent contact. Increased temperatures due to heated substances,
body heat etc. and a reduction of the effective layer thickness by stretching can lead to a consider-
able reduction of the breakthrough time. If in doubt, contact manufacturer. At an approx. 1.5 times
larger / smaller layer thickness, the respective breakthrough time is doubled / halved. The data apply
only to the pure substance. When transferred to substance mixtures, they may only be considered as
a guide.
• type of material
NBR (Nitrile rubber)
• material thickness

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Safety data sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439

>0,3 mm
• breakthrough times of the glove material
>480 minutes (permeation: level 6)
• other protection measures
Take recovery periods for skin regeneration. Preventive skin protection (barrier creams/ointments) is
recommended.
Respiratory protection

Respiratory protection necessary at: Aerosol or mist formation. Type: A (against organic gases and va-
pours with a boiling point of > 65 °C , colour code: Brown).
Environmental exposure controls
Keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties
Physical state liquid
Colour colourless
Odour characteristic
Melting point/freezing point -13,5 °C at 1 atm (ECHA)
Boiling point or initial boiling point and boiling 194 °C at 1 atm (ECHA)
range
Flammability this material is combustible, but will not ignite
readily
Lower and upper explosion limit 0,8 vol% (LEL)
Flash point 86,5 °C at 101,5 kPa (ECHA)
Auto-ignition temperature 294 °C at 1.013 mbar (ECHA)
Decomposition temperature not relevant
pH (value) not determined
Kinematic viscosity 5,584 mm²/s at 40 °C

Solubility(ies)
Water solubility 0,107 g/l at 23 °C (ECHA)

Partition coefficient
Partition coefficient n-octanol/water (log value): 3,5 (pH value: 5,7, 23 °C) (ECHA)

Vapour pressure 0,052 hPa at 20 °C

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Safety data sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439

Density and/or relative density

Density 0,828 g/cm³ at 15,56 °C (ECHA)

Relative vapour density 4,5 (air = 1)

Particle characteristics not relevant (liquid)

Other safety parameters

Oxidising properties none
9.2 Other information
Information with regard to physical hazard hazard classes acc. to GHS
classes: (physical hazards): not relevant
Other safety characteristics:
Surface tension 35,54 mN/m (298,2 K) (ECHA)

SECTION 10: Stability and reactivity

10.1 Reactivity
This material is not reactive under normal ambient conditions.
If heated
Vapours may form explosive mixtures with air.
10.2 Chemical stability
The material is stable under normal ambient and anticipated storage and handling conditions of tem-
perature and pressure.
10.3 Possibility of hazardous reactions

Violent reaction with: strong oxidiser, Acetic anhydride, Perchlorates, Acids

10.4 Conditions to avoid
Keep away from heat.
10.5 Incompatible materials
Rubber articles, different plastics
10.6 Hazardous decomposition products
Hazardous combustion products: see section 5.

SECTION 11: Toxicological information

11.1 Information on toxicological effects
Classification acc. to GHS
Acute toxicity
Shall not be classified as acutely toxic.

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Safety data sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439

Acute toxicity

Exposure route Endpoint Value Species Method Source

mg
oral LD50 >5.000 /kg rat ECHA

dermal LD50 >2.000 – 4.000 mg/ rabbit ECHA

kg

Skin corrosion/irritation
Shall not be classified as corrosive/irritant to skin.
Serious eye damage/eye irritation
Causes serious eye irritation.
Respiratory or skin sensitisation
Shall not be classified as a respiratory or skin sensitiser.
Germ cell mutagenicity
Shall not be classified as germ cell mutagenic.
Carcinogenicity
Shall not be classified as carcinogenic.
Reproductive toxicity
Shall not be classified as a reproductive toxicant.
Specific target organ toxicity - single exposure
Shall not be classified as a specific target organ toxicant (single exposure).
Specific target organ toxicity - repeated exposure
Shall not be classified as a specific target organ toxicant (repeated exposure).
Aspiration hazard
Shall not be classified as presenting an aspiration hazard.

Symptoms related to the physical, chemical and toxicological characteristics

• If swallowed
vomiting, gastrointestinal complaints
• If in eyes
Causes serious eye irritation
• If inhaled
headache, vertigo, fatigue, dizziness, narcosis
• If on skin
Frequently or prolonged contact with skin may cause dermal irritation
• Other information
none
11.2 Endocrine disrupting properties
Not listed.
11.3 Information on other hazards
There is no additional information.

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Safety data sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439

SECTION 12: Ecological information

12.1 Toxicity
Harmful to aquatic life with long lasting effects.
.

Aquatic toxicity (acute)

Endpoint Value Species Source Exposure

time

LC50 13,3 mg/l fish ECHA 96 h

Biodegradation
The substance is readily biodegradable.
12.2 Process of degradability
Theoretical Oxygen Demand: 2,948 mg/mg
Theoretical Carbon Dioxide: 2,703 mg/mg
12.3 Bioaccumulative potential
Does not significantly accumulate in organisms.

n-octanol/water (log KOW) 3,5 (pH value: 5,7, 23 °C) (ECHA)

12.4 Mobility in soil

Data are not available.
12.5 Results of PBT and vPvB assessment
Data are not available.
12.6 Endocrine disrupting properties
Not listed.
12.7 Other adverse effects
Data are not available.

SECTION 13: Disposal considerations

13.1 Waste treatment methods

This material and its container must be disposed of as hazardous waste. Dispose of contents/contain-
er in accordance with local/regional/national/international regulations.
Sewage disposal-relevant information
Do not empty into drains. Avoid release to the environment. Refer to special instructions/safety data
sheets.
13.2 Relevant provisions relating to waste
The allocation of waste identity numbers/waste descriptions must be carried out according to the
EEC, specific to the industry and process. Waste catalogue ordinance (Germany).

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Safety data sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439

13.3 Remarks
Waste shall be separated into the categories that can be handled separately by the local or national
waste management facilities. Please consider the relevant national or regional provisions.

SECTION 14: Transport information

14.1 UN number or ID number not subject to transport regulations
14.2 UN proper shipping name not assigned
14.3 Transport hazard class(es) none
14.4 Packing group not assigned
14.5 Environmental hazards non-environmentally hazardous acc. to the dan-
gerous goods regulations
14.6 Special precautions for user
There is no additional information.
14.7 Maritime transport in bulk according to IMO instruments
The cargo is not intended to be carried in bulk.

14.8 Information for each of the UN Model Regulations

Transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN) - Additional
information
Not subject to ADR, RID and ADN.
International Maritime Dangerous Goods Code (IMDG) - Additional information
Not subject to IMDG.
International Civil Aviation Organization (ICAO-IATA/DGR) - Additional information
Not subject to ICAO-IATA.

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
Relevant provisions of the European Union (EU)
Seveso Directive

2012/18/EU (Seveso III)

No Dangerous substance/hazard categories Qualifying quantity (tonnes) for the ap- Notes
plication of lower and upper-tier re-
quirements

not assigned

Deco-Paint Directive

VOC content 100 %

828 g/l

Industrial Emissions Directive (IED)

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Safety data sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439

VOC content 0%

VOC content 0 g/l

Directive on the restriction of the use of certain hazardous substances in electrical and
electronic equipment (RoHS)
not listed
Regulation concerning the establishment of a European Pollutant Release and Transfer
Register (PRTR)
not listed
Water Framework Directive (WFD)
not listed
Regulation on the marketing and use of explosives precursors
not listed
Regulation on drug precursors
not listed
Regulation on substances that deplete the ozone layer (ODS)
not listed
Regulation concerning the export and import of hazardous chemicals (PIC)
not listed
Regulation on persistent organic pollutants (POP)
not listed
National regulations(GB)
List of substances subject to authorisation (GB REACH, Annex 14) / SVHC - candidate list
not listed
Restrictions according to GB REACH, Annex 17

Dangerous substances with restrictions (GB REACH, Annex 17)

Name of substance Name acc. to inventory CAS No No

1-Octanol this product meets the criteria for classi- 3

fication in accordance with Regulation No
1272/2008/EC

Other information
Directive 94/33/EC on the protection of young people at work. Observe employment restrictions un-
der the Maternity Protection Directive (92/85/EEC) for expectant or nursing mothers.
National inventories
Country Inventory Status

AU AIIC substance is listed

CA DSL substance is listed

CN IECSC substance is listed

EU ECSI substance is listed

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Safety data sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439

Country Inventory Status

EU REACH Reg. substance is listed

JP CSCL-ENCS substance is listed

KR KECI substance is listed

MX INSQ substance is listed

NZ NZIoC substance is listed

PH PICCS substance is listed

TR CICR substance is listed

TW TCSI substance is listed

US TSCA substance is listed

Legend
AIIC Australian Inventory of Industrial Chemicals
CICR Chemical Inventory and Control Regulation
CSCL-ENCS List of Existing and New Chemical Substances (CSCL-ENCS)
DSL Domestic Substances List (DSL)
ECSI EC Substance Inventory (EINECS, ELINCS, NLP)
IECSC Inventory of Existing Chemical Substances Produced or Imported in China
INSQ National Inventory of Chemical Substances
KECI Korea Existing Chemicals Inventory
NZIoC New Zealand Inventory of Chemicals
PICCS Philippine Inventory of Chemicals and Chemical Substances (PICCS)
REACH Reg. REACH registered substances
TCSI Taiwan Chemical Substance Inventory
TSCA Toxic Substance Control Act

15.2 Chemical Safety Assessment

No Chemical Safety Assessment has been carried out for this substance.

SECTION 16: Other information

Indication of changes (revised safety data sheet)
Alignment to regulation:
Restructuring: section 9, section 14
Section Former entry (text/value) Actual entry (text/value) Safety-
relev-
ant

2.1 Classification acc. to GHS: yes

change in the listing (table)

2.1 The most important adverse physicochemical, yes

human health and environmental effects:
Spillage and fire water can cause pollution of
watercourses.

2.2 Labelling of packages where the contents do yes

not exceed 125 ml:
Signal word: Warning

2.2 Labelling of packages where the contents do yes

not exceed 125 ml:
change in the listing (table)

2.2 Labelling of packages where the contents do yes

not exceed 125 ml:
change in the listing (table)

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Safety data sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439

Section Former entry (text/value) Actual entry (text/value) Safety-

relev-
ant

2.3 Other hazards: Other hazards: yes

There is no additional information. This material is combustible, but will not ignite
readily.

2.3 Results of PBT and vPvB assessment: yes

According to the results of its assessment, this
substance is not a PBT or a vPvB.

Abbreviations and acronyms

Abbr. Descriptions of used abbreviations

ADN Accord européen relatif au transport international des marchandises dangereuses par voies de naviga-
tion intérieures (European Agreement concerning the International Carriage of Dangerous Goods by In-
land Waterways)

ADR Accord relatif au transport international des marchandises dangereuses par route (Agreement concern-
ing the International Carriage of Dangerous Goods by Road)

CAS Chemical Abstracts Service (service that maintains the most comprehensive list of chemical substances)

DGR Dangerous Goods Regulations (see IATA/DGR)

EC No The EC Inventory (EINECS, ELINCS and the NLP-list) is the source for the seven-digit EC number, an identi-
fier of substances commercially available within the EU (European Union)

EINECS European Inventory of Existing Commercial Chemical Substances

ELINCS European List of Notified Chemical Substances

GB REACH The REACH etc. (Amendment etc.) (EU Exit) Regulations 2019, SI 2019/758 (as amended)

GHS "Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Na-
tions

IATA International Air Transport Association

IATA/DGR Dangerous Goods Regulations (DGR) for the air transport (IATA)

ICAO International Civil Aviation Organization

IMDG International Maritime Dangerous Goods Code

LC50 Lethal Concentration 50%: the LC50 corresponds to the concentration of a tested substance causing 50 %
lethality during a specified time interval

LD50 Lethal Dose 50 %: the LD50 corresponds to the dose of a tested substance causing 50 % lethality during a
specified time interval

LEL Lower explosion limit (LEL)

NLP No-Longer Polymer

PBT Persistent, Bioaccumulative and Toxic

PNEC Predicted No-Effect Concentration

REACH Registration, Evaluation, Authorisation and Restriction of Chemicals

RID Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regula-
tions concerning the International carriage of Dangerous goods by Rail)

VOC Volatile Organic Compounds

vPvB Very Persistent and very Bioaccumulative

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Safety data sheet
acc. to Regulation (EC) No. 1907/2006 (REACH)

1-Octanol ≥99 %, for synthesis

article number: 4439

Key literature references and sources for data
Agreement concerning the International Carriage of Dangerous Goods by Road (ADR). Regulations
concerning the International Carriage of Dangerous Goods by Rail (RID). International Maritime Dan-
gerous Goods Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).
List of relevant phrases (code and full text as stated in section 2 and 3)
Code Text

H319 Causes serious eye irritation.

H412 Harmful to aquatic life with long lasting effects.

Disclaimer
This information is based upon the present state of our knowledge. This SDS has been compiled and
is solely intended for this product.

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