S.Y.B.PHARMACY

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Sanjay Ghodawat University

Kolhapur
Established under section 2(f) of UGC act 1956
Sanjay Ghodawat University Act XL of 2017 of Govt. of Maharashtra
Approved by PCI, COA & AICTE

Empowering Lives Globally!

School of Pharmaceutical Sciences

S. Y. B. Pharm.
Curriculum
Academic Year 2023-24
Revised Ordinance Governing
Bachelor of Pharmacy (B. Pharm.)
Degree Course
Pharmacy Council of India.

Rules & Syllabus for the Bachelor of


Pharmacy
(S. Y. B. Pharm) Course

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 2


Index
Sr. CONTENT Page
No No.
I SANJAY GHODAWAT UNIVERSITY KOLHAPUR 4
VISION 5
MISSION 5
CORE VALUES 5
QUALITY POLICY 5
OUTCOME BASED EDUCATION (OBE) MODEL 6
II CHAPTER- I: REGULATIONS 9
III CHAPTER - II: SYLLABUS 30
A SEMESTER III 31
BP301T. PHARMACEUTICAL ORGANIC CHEMISTRY-II (THEORY) 32
BP305P. PHARMACEUTICAL ORGANIC CHEMISTRY-II (PRACTICAL) 34
BP302T. PHYSICAL PHARMACEUTICS-I (THEORY) 35
BP306P. PHYSICAL PHARMACEUTICS-I (PRACTICAL) 37
BP303T. PHARMACEUTICAL MICROBIOLOGY (THEORY) 38
BP307P. PHARMACEUTICAL MICROBIOLOGY (PRACTICAL) 40
BP304T. PHARMACEUTICAL ENGINEERING (THEORY) 41
BP308P. PHARMACEUTICAL ENGINEERING (PRACTICAL) 43
BP105RT. COMMUNICATION SKILLS (THEORY) 44
BP105RP. COMMUNICATION SKILLS (PRACTICAL) 46
B SEMESTER IV 47
BP401T. PHARMACEUTICAL ORGANIC CHEMISTRY-III (THEORY) 48
BP402T. MEDICINAL CHEMISTRY-I (THEORY) 50
BP406P. MEDICINAL CHEMISTRY-I (PRACTICAL) 53
BP403T. PHYSICAL PHARMACEUTICS-II (THEORY) 54
BP407P. PHYSICAL PHARMACEUTICS-II (PRACTICAL) 56
BP404T. PHARMACOLOGY-I (THEORY) 57
BP408P. PHARMACOLOGY-I (PRACTICAL) 60
BP405T. PHARMACOGNOSY AND PHYTOCHEMISTRY-I (THEORY) 62
BP409P. PHARMACOGNOSY AND PHYTOCHEMISTRY-I (PRACTICAL) 64
BP205RT. COMPUTER APPLICATIONS IN PHARMACY (THEORY) 65
BP210RP. COMPUTER APPLICATIONS IN PHARMACY (PRACTICAL) 67
BP211T. CONSTITUTION OF INDIA AND PROFESSIONAL ETHICS- (THEORY) 68

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 3


SANJAY GHODAWAT UNIVERSITY KOLHAPUR
Sanjay Ghodawat University (SGU) is established in the Academic Year 2017-18, as a State
Private University under Govt. of Maharashtra Act No. XL of 2017 dated 3rd May 2017, with
the approval of the UGC and the State Government. "For the true measure of giving is giving
without measure." Spread across 150 Acres, Sou. Sushila DanchandGhodawat Charitable
Trust's Sanjay Ghodawat University (SGU) is situated in a serene atmosphere amidst idyllic
hills and lush green meadows to study in harmony with Nature. The Institution aspires to run
along the lines of best-in-the-world education and become a world-class institution where
the teaching-learning process gets a far deeper meaning. SGUalways stands as the guiding
star of brilliance, quality, and deliverance beyond expectations. Innovativeness and
Creativity are the hallmarks of a genius enterprise and SGU stands to be a stage where these
qualities would be nurtured, encouraged, andblossomed. The genius is incomplete without
the sense of social responsibility and SGU's ultimate goal remains the development of an
attitude of gratitude that freely gives back without expectations. The Sanjay Ghodawat
University stands as a beacon of light to guidethe younger generation of the day on the right
path to fulfillment in career and life. The USP of the University is its research-based
curriculum and academically-oriented teaching staff. The world-class ambiance and
infrastructure help the students to easily accommodatethemselves in an environment that is
conducive to the teaching-learning process. Hands-on experience, challenge-based case
studies, maximum participation of students in the classroom, use of modern digital
technology, smart classrooms, solution-oriented thinking promotion, stress on research and
innovation, international tie-ups, choice-based credit system for flexibility in choosing areas
of interest, etc. are some of the features of the University. The university will help students
develop as unique individual-to be educated as a whole person, intellectually, emotionally,
socially, ethically, and spiritually. The educational program designs are worked out
meticulously in line with best in class universities with a special focus on:
 Flexible Choice Based Credit System
 OBE-Outcome Based Education System
 Experiential Learning
 Project-Based Learning
 Case-Based Learning
 Training need analysis based on Performance Appraisal System
 Active Learning tools for effective delivery
 Mentoring / Proctorship
 Online learning /Self-learning platforms
 Flipped Classroom concept
 Effective Student Feedback Mechanism

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 4


SCHOOL OF PHARMACEUTICAL SCIENCES

Vision
To be recognized as the to pharmaceutical education provider in the region by imparting high level of
academic and research outcomes which are aligned with better regional and global needs.

Mission
 M 1 – Outcomes based quality education:
To provide outcomes based quality education to produce competent and ethical pharmacy
professionals to face emerging challenges of the globalized pharmaceutical industry.

 M2-Research and lifelong learning:


To establish the strong industry connections, develop research profile and lifelong learning to
optimize adequate care and healthcare delivery.

 M3-Inculcating values and ethics:


To inculcate the professional ethics and human values in pharmacy professionals and
developing them to serve the healthcare needs of society.

 M4- Fostering leadership qualities:


To provide conducive environment to boost the practical skills, entrepreneur traits and
leadership qualities in budding pharmacists to stay ahead in the competitive world.

CORE VALUES
 Integrity
 Transparency
 Accountability
 Equality
 Empathy
 Stewardship

QUALITY POLICY
Sanjay Ghodawat University is committed to establish high standards in value-based
qualityeducation to enhance and nurture young minds to excel in their chosen profession
and develop into socially responsible citizens through resourceful collaboration, innovation
and research

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 5


OUTCOME BASED EDUCATION (OBE) MODEL
Sanjay Ghodawat University (SGU) has implemented the OBE model of education, which
is a learner cantered approach. SGU has witnessed a sea change in the entire academic
system with the implementation of all three components of OBE – Design, Delivery, and
Assessment. The SGU model of autonomy focuses on experiential learning which believes
in learning by doing. This is achieved through hands-on experience, industrial assignments,
mini-projects, and live problem solving and collaboration with industries.
SGU is set into dynamics of transformation and witnessing a shift in focus from teaching to
learning and the entire academic system of SGU is designed to provide multiple learning
opportunities for students to acquire and demonstrate the Knowledge, Skills, and Attitudes
(KSA) for rewarding career. The Vision and Mission of the Management, the contribution
from eminent BOG members and knowledgeable members of Academic Council and Board
of Studies, the motivation and drive of the Director, the relentless efforts of the fellow Deans
and Head of Departments and all teaching and non-teaching staff along witha commitment
to the learning of students made it possible to successfully transform the institute and stand
out to carve a niche for itself as an Institute of repute.
OBE is an approach to curriculum design and teaching that focuses on what students
should be able to do (attained) at the end of the course/ program. Outcome-based education
(OBE) is a student-centered instruction model that focuses on measuring student
performance through outcomes. Outcomes include knowledge, skills, and attitudes (KSA).
Its focus remains on the evaluation of outcomes of the program by stating the knowledge,
skill and behavior a graduate is expected to attain upon completion of a program and after
4 – 5 years of graduation. In the OBE model, the required knowledge and skill sets for a
particular degree are predetermined and the students are evaluated for all the required
parameters (Outcomes) during the program.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 6


The OBE model measures the progress of the graduate in three parameters, which are
 Program Educational Objectives (PEO)
 Program Outcomes (PO)
 Course Outcomes (CO)

Program Educational Objectives (PEO) are broad statements that describe the career and
professional accomplishments that the program is preparing the graduates to achieve.
PEO’sare measured 4-5 years after graduation. Program outcomes are narrower statements
that describe what students are expected to know and be able to do by the time of
graduation. They must reflect the Graduate attributes. Course outcomes are the measurable
parameters that evaluate each student's performance for each course that the student
undertakes every semester.

The various assessment tools for measuring Course Outcomes include Tests and End
Semester Examinations, Tutorials, Assignments, Project work, Labs, Presentations,
Employer/Alumni Feedback, etc, These course outcomes are mapped to Graduate attributes
and Program outcomes based on relevance. This evaluation pattern helps Institutions to
measure the Program Outcome. The Program Educational Objective ismeasure through
Employer satisfaction survey (Yearly), Alumni survey (Yearly), Placement records, and
higher education records.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 7


Special Features of OBE
 OBE is an educational process that focuses on what students can do or the qualities
they should develop after they are taught.
 OBE involves the restructuring of curriculum, assessment, and reporting practices
in education to reflect the achievement of high order learning and mastery rather than
accumulation of course credits.
 Both structures and curricula are designed to achieve those capabilities or qualities.
 Discourages traditional education approaches based on direct instruction of facts and
standard methods.
 It requires that the students demonstrate that they have learned the required skills and
content.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 8


CHAPTER-I:
REGULATIONS

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 9


1. Short Title and Commencement
These regulations shall be called as “The Revised Regulations for the B. Pharm. Degree
Program (CBCS) of the Pharmacy Council of India, New Delhi”. They shall come into effect
from the Academic Year 2016-17. The regulations framed are subject to modifications from
time to time by the Pharmacy Council of India.
2. Minimum qualification for admission
First-year B. Pharm:
Candidate shall have passed 10+2 examination conducted by the respective state/central
government authorities recognized as equivalent to 10+2 examination by the Associationof
Indian Universities (AIU) with English as one of the subjects and Physics, Chemistry,
Mathematics (P.C.M) and or Biology (P.C.B / P.C.M.B.) as optional subjects individually.
Any other qualification approved by the Pharmacy Council of India as equivalent to any of
the above examinations.
B. Pharm lateral entry (to third semester):
A pass in D. Pharm. course from an institution approved by the Pharmacy Council of India
under section 12 of the Pharmacy Act.
3. Duration of the program
The course of study for B. Pharm shall extend over a period of eight semesters (four
academic years) and six semesters (three academic years) for lateral entry students. The
curricula and syllabi for the program shall be prescribed from time to time by the Pharmacy
Council of India, New Delhi.
4. Medium of instruction and examinations
The medium of instruction and examination shall be in English.
5. Working days in each semester
Each semester shall consist of not less than 100 working days. The odd semesters shall be
conducted from the month of June/July to November/December and the even semesters shall
be conducted from December/January to May/June in every calendar year.
6. Attendance and progress
A candidate is required to put in at least 80% attendance in individual courses considering
theory and practical separately. The candidate shall complete the prescribed course
satisfactorily to be eligible to appear for the respective examinations.
7. Program/Course credit structure
As per the philosophy of Credit-Based Semester System, a certain quantum of academic
work viz. theory classes, tutorial hours, practical classes, etc. are measured in terms of
credits. On satisfactory completion of the courses, a candidate earns credits. The amount of
credit associated with a course is dependent upon the number of hours of instruction per
week in that course. Similarly, the credit associated with any of the other academic,
co/extra-curricular activities is dependent upon the quantum of work expected to be put in
for each of these activities per week.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 10


Credit assignment
Theory and Laboratory courses
Courses are broadly classified as Theory and Practical. Theory courses consist of lecture
(L) and /or tutorial (T) hours, and Practical (P) courses consist of hours spent in the
laboratory. Credits (C) for a course is dependent on the number of hours of instruction per
week in that course and is obtained by using a multiplier of one (1) for lecture and tutorial
hours, and a multiplier of half (1/2) for practical (laboratory) hours. Thus, for example, a
theory course having three lectures and one tutorial per week throughout the semester carries
a credit of 4. Similarly, a practical having four laboratory hours per week throughout the
semester carries a credit of 2.
Sr. Component Hours Credit
No
B. Pharm (Direct)
1 Theory 1hr 1
2 Tutorial 1hr 1
3 Practical Hr ½ per Hr
Lateral Entry
D. Pharm 52
Remedial Course Communication Skills (Theory and 7
Practical) and ‘Computer Applications in Pharmacy)

Minimum credit requirements


The minimum credit point required for award of B. Pharm. degree is 208. These credits are
divided into Theory courses, Tutorials, Practical, Practice School, and Projects over the
duration of eight semesters. The credits are distributed semester-wise as shown in Table
IX. Courses generally progress in sequences, building competencies and their positioning
indicates certain academic maturity on the part of the learners. Learners are expected to
follow the semester-wise schedule of courses given in the syllabus.
The lateral entry students shall get 52 credit points transferred from their D. Pharm
program. Such students shall take up additional remedial courses of ‘Communication
Skills’ (Theory and Practical) and ‘Computer Applications in Pharmacy’ (Theory and
Practical) equivalentto 3 and 4 credit points respectively, a total of 7 credit points to attain
59 credit points, the maximum of I and II semesters.
8. Academic work
A regular record of attendance both in Theory and Practical shall be maintained by the
teaching staff of respective courses.
9. Course of study
The course of study for B. Pharm shall include Semester Wise Theory & Practical as given
in Table – I to VIII. The number of hours to be devoted to each theory, tutorial and practical
course in any semester shall not be less than that shown in Table – I to VIII.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 11


Table I: Course of study for Semester-I

Course code Name of the course No. of Tuto Credit


hours rial points
BP101T Human Anatomy and Physiology-I (Theory) 3 1 4
BP102T Pharmaceutical Analysis-I (Theory) 3 1 4
BP103T Pharmaceutics-I (Theory) 3 1 4
BP104T Pharmaceutical Inorganic Chemistry (Theory) 3 1 4
BP105T Communication skills (Theory) * 2 - 2
BP106RBT Remedial Biology/ 2 - 2
BP106RMT Remedial Mathematics (Theory)*
BP107P Human Anatomy and Physiology (Practical) 4 - 2
BP108P Pharmaceutical Analysis-I (Practical) 4 - 2
BP109P Pharmaceutics-I (Practical) 4 - 2
BP110P Pharmaceutical Inorganic Chemistry (Practical) 4 - 2
BP111P Communication skills (Practical)* 2 - 1
BP112RBP Remedial Biology (Practical)* 2 - 1
Total 32/34$/36# 4 27/29$/30#

#
Applicable ONLY for the students who have studied Mathematics / Physics / Chemistry at HSC
and appearing for Remedial Biology (RB) course.
$Applicable ONLY for the students who have studied Physics / Chemistry / Botany / Zoology at
HSC and appearing for Remedial Mathematics (RM) course.
* Non University Examination (NUE)

Table II: Course of study for Semester-II

Course Name of the course No. of Tutorial Credit


Code hours points
BP201T Human Anatomy and Physiology-II (Theory) 3 1 4
BP202T Pharmaceutical Organic Chemistry-I (Theory) 3 1 4
BP203T Biochemistry (Theory) 3 1 4
BP204T Pathophysiology (Theory) 3 1 4
BP205T Computer Applications in Pharmacy (Theory)* 3 - 3
BP206T Environmental Sciences (Theory)* 3 - 3
BP207P Human Anatomy and Physiology-II (Practical) 4 - 2
BP208P Pharmaceutical Organic Chemistry-I (Practical) 4 - 2
BP209P Biochemistry (Practical) 4 - 2
BP210P Computer Applications in Pharmacy (Practical)* 2 - 1
Total 32 4 29
*Non University Examination (NUE)

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 12


Table III: Course of study for Semester-III

Course Name of the course No. of Tutorial Credit


code hours points
BP301T Pharmaceutical Organic Chemistry-II (Theory) 3 1 4
BP302T Physical Pharmaceutics-I (Theory) 3 1 4
BP303T Pharmaceutical Microbiology (Theory) 3 1 4
BP304T Pharmaceutical Engineering (Theory) 3 1 4
BP305P Pharmaceutical Organic Chemistry-II (Practical) 4 - 2
BP306P Physical Pharmaceutics-I (Practical) 4 - 2
BP307P Pharmaceutical Microbiology (Practical) 4 - 2
BP308P Pharmaceutical Engineering (Practical) 4 - 2
BP105RT Communication skills (Theory) * # 2# - 2#
#
BP105RP Communication skills (Practical)* # 2 - 1#
Total 28/32# 4 24/27#
*Non University Examination (NUE)
#
Applicable ONLY for the LATERAL ENTRY (Direct Second year) students

Table IV: Course of study for Semester-IV

Course Name of the course No. of Tutorial Credit


code hours points
BP401T Pharmaceutical Organic Chemistry-III (Theory) 3 1 4
BP402T Medicinal Chemistry-I (Theory) 3 1 4
BP403T Physical Pharmaceutics-II (Theory) 3 1 4
BP404T Pharmacology-I (Theory) 3 1 4
BP405T Pharmacognosy and Phytochemistry-I (Theory) 3 1 4
BP406P Medicinal Chemistry-I (Practical) 4 - 2
BP407P Physical Pharmaceutics-II (Practical) 4 2
BP408P Pharmacology-I (Practical) 4 - 2
BP409P Pharmacognosy and Phytochemistry-I (Practical) 4 - 2
BP205RT Computer Applications in Pharmacy (Theory)* # 2# - 3#
BP210RP Computer Applications in Pharmacy (Practical)* # 2# - 1#
BP211T Constitution of India and Professional Ethics- (T)* 2
Total 33/36# 5 28/32#
*Non University Examination (NUE)
#
Applicable ONLY for the LATERAL ENTRY (Direct Second Year) students

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 13


Table V: Course of study for Semester-V

Course Name of the course No. of Tutorial Credit


code hours points
BP501T Medicinal Chemistry-II (Theory) 3 1 4
BP502T Industrial Pharmacy-I (Theory) 3 1 4
BP503T Pharmacology-II (Theory) 3 1 4
BP504T Pharmacognosy and Phytochemistry-II (Theory) 3 1 4
BP505T Pharmaceutical Jurisprudence (Theory) 3 1 4
BP506P Industrial Pharmacy-I (Practical) 4 - 2
BP507P Pharmacology-II (Practical) 4 - 2
BP508P Pharmacognosy and Phytochemistry-II (Practical) 4 - 2
Total 27 5 26

Table VI: Course of study for Semester-VI

Course Name of the course No. of Tutorial Credit


code hours points
BP601T Medicinal Chemistry-III (Theory) 3 1 4
BP602T Pharmacology-III (Theory) 3 1 4
BP603T Herbal Drug Technology (Theory) 3 1 4
BP604T Biopharmaceutics and Pharmacokinetics (Theory) 3 1 4
BP605T Pharmaceutical Biotechnology (Theory) 3 1 4
BP606T Quality Assurance (Theory) 3 1 4
BP607P Medicinal Chemistry-III (Practical) 4 - 2
BP608P Pharmacology-III (Practical) 4 - 2
BP609P Herbal Drug Technology (Practical) 4 - 2
Total 30 6 30

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 14


Table VII: Course of study for Semester-VII

Course Name of the course No. of Tutorial Credit


code hours points
BP701T Instrumental Methods of Analysis (Theory) 3 1 4
BP702T Industrial Pharmacy-II (Theory) 3 1 4
BP703T Pharmacy Practice (Theory) 3 1 4
BP704T Novel Drug Delivery System (Theory) 3 1 4
BP705P Instrumental Methods of Analysis (Practical) 4 - 2
BP706PS Practice School* 12 - 6
Total 28 5 24
* Non University Examination (NUE)

Table VIII: Course of study for semester VIII

Course Name of the course No. of Tutorial Credit


code hours points
BP801T Biostatistics and Research Methodology 3 1 4
BP802T Social and Preventive Pharmacy 3 1 4
BP803ET Pharma Marketing Management
BP804ET Pharmaceutical Regulatory Science
BP805ET Pharmacovigilance
BP806ET Quality Control and Standardization of Herbals
BP807ET Computer Aided Drug Design 3+3= 4+4=
BP808ET Cell and Molecular Biology 6 1+1=2 8
BP809ET Cosmetic Science
BP810ET Experimental Pharmacology
BP811ET Advanced Instrumentation Techniques
BP812ET Dietary Supplements and Nutraceuticals
BP813PW Project Work 12 - 6
Total 24 4 22

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 15


Table IX: Semester wise credits distribution

Semester Credit Points


Lateral entry students
$ #
I 27/29 /30 52
II 29 (Tansfered from D. Pharm)
III 24 27
IV 28 32
V 26 26
VI 30 30
VII 24 24
VIII 22 22
Extracurricular/ Co curricular activities 01* 01*
Total credit points for the program 210/212$/213# + (01*) 213 + (01*)

* The credit points assigned for extracurricular and/or co-curricular activities shall be given by the
Principals of the colleges and the same shall be submitted to the University. The criteria to acquire this
credit point shall be defined by the colleges from time to time.
$Applicable ONLY for the students studied Physics/Chemistry/Botany/Zoology at HSC and appearing for
Remedial Mathematics course.
#Applicable ONLY for the students studied Mathematics/Physics/Chemistry at HSC and appearing for
Remedial Biology course.

10. Program Committee


1. The B. Pharm. program shall have a Program Committee constituted by the Head of
the institution in consultation with all the Heads of the departments.
2. The composition of the Program Committee shall be as follows:
A senior teacher shall be the Chairperson; One Teacher from each department
handling B. Pharm courses; and four student representatives of the program (one
from each academic year), nominated by the Head of the institution.
3. Duties of the Program Committee:
i. Periodically reviewing the progress of the classes.
ii. Discussing the problems concerning curriculum, syllabus and the conduct of
classes.
iii. Discussing with the course teachers on the nature and scope of assessment for
the course and the same shall be announced to the students at the beginning of
respective semesters.
iv. Communicating its recommendation to the Head of the institution on academic
matters.
v. The Program Committee shall meet at least thrice in a semester preferably at
the end of each Sessional exam (Internal Assessment) and before the end
semester exam.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 16


11. Examinations/Assessments
The scheme for internal assessment and end semester examinations is given in Table – X.
End semester examinations
The End Semester Examinations (ESE) for each theory and practical course through
semesters I to VIII shall be conducted by the university except for the subjects with
asterix symbol (*) in table I and II for which examinations shall be conducted by the subject
experts at college level and the marks/grades shall be submitted to the university.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 17


Table X: - SEMESTER - III
Course Course Title L T P C Component Exam WT Passing
Code (Marks) Min. (%)
BP301T Pharmaceutical 3 1 - 4 Theory CA 10 10
Organic (100) Sessional-1 15
Chemistry-II 15 50
Sessional-2 15
(Theory) ESE 75
BP302T Physical 3 1 - 4 Theory CA 10 10 50
Pharmaceutics-I (100) Sessional-1 15
(Theory) 15
Sessional-2 15
ESE 75
BP303T Pharmaceutical 3 1 - 4 Theory CA 10 10 50
Microbiology (100) Sessional-1 15
(Theory) 15
Sessional-2 15
ESE 75
BP304T Pharmaceutical 3 1 - 4 Theory CA 10 10 50
Engineering (100) Sessional-1 15
(Theory) 15
Sessional-2 15
ESE 75
BP305P Pharmaceutical - - 4 2 Practical CA 05 05 50
Organic (50) Sessional-1 10
Chemistry-II 10
Sessional-2 10
(Practical) ESE 35
BP306P Physical - - 4 2 Practical CA 05 05 50
Pharmaceutics-I (50) Sessional-1 10
10
(Practical) Sessional-2 10
ESE 35
BP307P Pharmaceutical - - 4 2 Practical CA 05 05 50
Microbiology (50) Sessional-1 10
(Practical) 10
Sessional-2 10
ESE 35
BP308P Pharmaceutical - - 4 2 Practical CA 05 05 50
Engineering (50) Sessional-1 10
(Practical) 10
Sessional-2 10
ESE 35
BP105RT Communication 2* - - 2* Theory CA 05 05 50
Skill (Theory)* (50) Sessional-1 10
10
Sessional-2 10
ESE 35
BP111RP Communication - - 2* 1* Practical CA 05 05 50
Skill (25) Sessional-1 05
05
(Practical)* Sessional-2 05
ESE 15
Total 12 4 16 24
Total (Lateral entry) 14 18 27
*Applicable only to lateral entry student only (For 3 credits)

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 18


Table X: SEMESTER-IV
Course Course Title L T P C Componen Exam WT Passing
Code t(Marks) Min (%)
BP401T PharmaceuticalOrganic 3 1 - 4 Theory CA 10 10
Chemistry-III (Theory) (100) Sessional-1 15 50
15
Sessional-2 15
ESE 75
BP402T Medicinal 3 1 - 4 Theor CA 10 10 50
Chemistry-I(Theory) y Sessional-I 15
(100) 15
Sessional-II 15
ESE 75
BP403T Physical Pharmaceutics- 3 1 - 4 Theor CA 10 10 50
II (Theory) y Sessional-I 15
(100) 15
Sessional-II 15
ESE 75
BP404T Pharmacology-I(Theory) 3 1 - 4 Theor CA 10 10 50
y Sessional-I 15
(100) 15
Sessional-II 15
ESE 75
BP405T Pharmacognosyand 3 1 - 4 Theor CA 10 10 50
Phytochemistry y Sessional-I 15
(100) 15
-I (Theory) Sessional-II 15
ESE 50
BP406T Medicinal - - 4 2 Practica CA 05 05 50
Chemistry- l (50) Sessional-I 10
I(Practical) 10
Sessional-II 10
ESE 35
BP407P Physical Pharmaceutics- - - 4 2 Practica CA 05 05 50
II (Practical) l (50) Sessional-I 10
10
Sessional-II 10
ESE 35
BP408P Pharmacology-I(Practical) - - 4 2 Practica CA 05 05 50
l (50) Sessional-I 10
10
Sessional-II 10
ESE 35
BP409P Pharmacognosyand - - 4 2 Practica CA 05 05 50
Phytochemistry l (50) Sessional-I 10
-I (Practical) 10
Sessional-II 10
ESE 35
BP205RT Computer Application 3* - - 3* Theory(75) CA 10 10 50
inPharmacy (Theory)* Sessional-I 15
15
Sessional-II 15
ESE 50
BP210RP Computer Application - - 2* 1* Practical CA 05 05 50
inPharmacy (Practical)* (25) Sessional-I 05
Sessional-II 05 05
ESE 15
BP211T Constitution of India and 2 Theory ESE 100 40
Professional Ethics (T)
Total 17 5 16 28
Total (Lateral entry) 18 18 32
* Applicable to lateral entry students only (For 4 credits)

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 19


Internal assessment: Continuous mode
The marks allocated for Continuous mode of Internal Assessment shall be awarded as per the
scheme given below.

Table XI: Scheme for awarding internal assessment: Continuous mode

Theory
Criteria Maximum
Marks
Attendance (Refer Table–XII) 4 2
Academic activities (Average of any 3 activities e.g. quiz, assignment, 3 1.5
open book test, field work, group discussion and seminar)
Student – Teacher interaction 3 1.5
Total 10 5
Practical
Attendance (Refer Table–XII) 2
Based on Practical Records, Regular viva voce, etc. 3
Total 5

Table XII: Guidelines for the allotment of marks for attendance

Percentage of Attendance Theory Practical


95 – 100 4 2
90 – 94 3 1.5
85 – 89 2 1
80 – 84 1 0.5
Less than 80 0 0

Sessional Exams
Two sessional exams shall be conducted for each theory/practical course as per the schedule
fixed by the college(s). The scheme of question paper for theory and practical sessional
examinations is given below. The average marks of two sessional exams shall be computed
for internal assessment as per the requirements given in tables–X.
Sessional exam shall be conducted for 30 marks for theory and shall be computed for 15
marks. Similarly Sessional exam for practical shall be conducted for 40 marks and shall be
computed for 10 marks.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 20


Question paper pattern for theory Sessional examinations

For subjects having University examination

I Multiple Choice Questions (MCQs) (10 x 1) 10 x 1 = 10


OR
Objective Type Questions (5 x 2) 05 x 2 = 10
(Answer all questions)
II Long Answer Questions (Answer 1 out of 2) 01 x 10 = 10

III Short Answers (Answer 2 out of 3) 02 x 05 = 10

Total 30 marks

For subjects having Non University Examination

I Long Answers (Answer 1 out of 2) 1 x 10 = 10

II Short Answers (Answer 4 out of 6) 4 x 5 = 20

Total 30 marks

Question paper pattern for practical sessional examinations

I Synopsis 10
II Experiments
Major experiment 15
Minor experiment 10
III Viva voce 05

Total 40 marks

12. Promotion and award of grades


A student shall be declared PASS and eligible for getting grade in a course of B. Pharm
program if he/she secures at least 50% marks in that particular course including internal
assessment. For example, to be declared as PASS and to get grade, the student has to secure
a minimum of 50 marks for the total of 100 including continuous mode of assessment and
end semester theory examination and has to secure a minimum of 25 marksfor the total 50
including internal assessment and end semester practical examination.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 21


13. Carry forward of marks
In case a student fails to secure the minimum 50% in any Theory or Practical course as
specified in 12, then he/she shall reappear for the end semester examination of that course.
However, his/her marks of the Internal Assessment shall be carried over and he/she shall
be entitled for grade obtained by him/her on passing.
14. Improvement of internal assessment
A student shall have the opportunity to improve his/her performance only once in the
Sessional exam component of the internal assessment. The re-conduct of the Sessional exam
shall be completed before the commencement of next end semester theory examinations.
15. Re-examination of end semester examinations
Reexamination of end semester examination shall be conducted as per the schedule given
in table XIII. The exact dates of examinations shall be notified from time to time.
Table XIII: Tentative schedule of end semester examinations

Semester For Regular Candidates For Failed Candidates


I, III, V and VII November / December May / June
II, IV, VI and VIII May / June November / December

Question paper pattern for end semester theory examinations

For 75 marks paper


I Multiple Choice Questions(MCQs) OR 20 x 1= 20 OR
Objective Type Questions (10 x 2) 10 x 2= 20
(Answer all the questions)
II Long Answers (Answer 2 out of 3) 2 x 10 = 20
III Short Answers (Answer 7 out of 9) 7 x 5 = 35
Total 75 marks
For 50 marks paper
I. Long Answers (Answer 2 out of 3) 2 x 10 = 20
II. Short Answers (Answer 6 out of 8) 6 x 05 = 30
Total 50 marks
For 35 marks paper
I. Long Answers (Answer 1 out of 2) 1 x 10 =10
II. Short Answers (Answer 5 out of 7) 5 x 5 = 25
Total 35 marks
Question paper pattern for end semester practical examinations
I. Synopsis 5
Experiments 25
Viva voce 5
Total 35 marks

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 22


16. Academic Progression:
No student shall be admitted to any examination unless he/she fulfills the norms given in 6.
Academic progression rules are applicable as follows:
A student shall be eligible to carry forward all the courses of I, II and III semesters till the
IV semester examinations. However, he/she shall not be eligible to attend the courses of V
semester until all the courses of I and II semesters are successfully completed.
A student shall be eligible to carry forward all the courses of III, IV and V semesters till the VI
semester examinations. However, he/she shall not be eligible to attend the courses of VII
semester until all the courses of I, II, III and IV semesters are successfully completed.
A student shall be eligible to carry forward all the courses of V, VI and VII semesters till the
VIII semester examinations. However, he/she shall not be eligible to get the course
completion certificate until all the courses of I, II, III, IV, V and VI semesters are
successfully completed.
A student shall be eligible to get his/her CGPA upon successful completion of the courses
of I to VIII semesters within the stipulated time period as per the norms specified in 26.
A lateral entry student shall be eligible to carry forward all the courses of III, IV and V
semesters till the VI semester examinations. However, he/she shall not be eligible to attend
the courses of VII semester until all the courses of III and IV semesters are successfully
completed.
A lateral entry student shall be eligible to carry forward all the courses of V, VI and VII
semesters till the VIII semester examinations. However, he/she shall not be eligible to get
the course completion certificate until all the courses of III, IV, V and VI semesters are
successfully completed.
A lateral entry student shall be eligible to get his/her CGPA upon successful completion of
the courses of III to VIII semesters within the stipulated time period as per the norms
specified in 26.
Any student who has given more than 4 chances for successful completion of I/III semester
courses and more than 3 chances for successful completion of II/IV semester courses shall
be permitted to attend V/VII semester classes ONLY during the subsequent academic year
as the case may be. In simpler terms there shall NOT be any ODD BATCH for any semester.
Note: Grade AB should be considered as failed and treated as one head for deciding
academic progression. Such rules are also applicable for those students who fail to register
for examination(s) of any course in any semester.
17. Grading of performances
Letter grades and grade points allocations:
Based on the performances, each student shall be awarded a final letter grade at the end of
the semester for each course. The letter grades and their corresponding grade points are given
in Table–XIV.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 23


Table XIV: Letter grades and grade points equivalent to Percentage of marks and performances.

Percentage of Letter Grade Grade Point Performance


Marks Obtained
90.00 – 100 O 10 Outstanding
80.00 – 89.99 A 9 Excellent
70.00 – 79.99 B 8 Good
60.00 – 69.99 C 7 Fair
50.00 – 59.99 D 6 Average
Less than 50 F 0 Fail
Absent AB 0 Fail
A learner who remains absent for any end semester examination shall be assigned a letter
grade of AB and a corresponding grade point of zero. He/she should reappear for the said
evaluation/examination in due course.
18. The Semester grade point average (SGPA)
The performance of a student in a semester is indicated by a number called ‘Semester Grade
Point Average’ (SGPA). The SGPA is the weighted average of the grade points obtained in
all the courses by the student during the semester. For example, if a student takes five courses
(Theory/Practical) in a semester with credits C1, C2, C3, C4 and C5 and the student’s
grade points in these courses are G1, G2, G3, G4 and G5, respectively, and then students’
SGPA is equal to:
C1G1 + C2G2 + C3G3 + C4G4+ C5G5
SGPA= C1 + C2 + C3 + C4+ C5

The SGPA is calculated to two decimal points. It should be noted that, the SGPA for any
semester shall take into consideration the F and ABS grade awarded in that semester. For
example if a learner has F or ABS grade in course 4, the SGPA shall then be computed as:
C1G1 + C2G2 + C3G3 + C4* ZERO + C5G5
SGPA= C1 + C2 + C3 + C4+ C5

19. Cumulative Grade Point Average (CGPA)


The CGPA is calculated with the SGPA of all the VIII semesters to two decimal points and
is indicated in final grade report card/final transcript showing the grades of all VIIIsemesters
and their courses. The CGPA shall reflect the failed status in case of F grade(s), till the
course(s) is/are passed. When the course(s) is/are passed by obtaining a pass grade on
subsequent examination(s) the CGPA shall only reflect the new grade and not the fail grades
earned earlier. The CGPA is calculated as:
C1S1 + C2S2 + C3S3 + C4S4+ C5S5+ C6S6+ C7S7+ C8S8
CGPA=
C1 + C2 + C3 + C4+ C5+ C6+ C7+ C8

where C1, C2, C3,…. is the total number of credits for semester I,II,III,…. and S 1,S2, S3,….is
the SGPA of semester I,II,III,…. .

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 24


20. Declaration of class
The class shall be awarded on the basis of CGPA as follows:
First Class with Distinction = CGPA of. 7.50 and above

First Class = CGPA of 6.00 to 7.49


Second Class = CGPA of 5.00 to 5.99

21. Project work


All the students shall undertake a project under the supervision of a teacher and submit a
report. The area of the project shall directly relate any one of the elective subject opted by
the student in Semester-VIII. The project shall be carried out in group not exceeding 5 in
number. The project report shall be submitted in triplicate (typed & bound copy not less than
25 pages).
The internal and external examiner appointed by the University shall evaluate the project
at the time of the Practical examinations of other semester(s). Students shall be evaluatedin
groups for four hours (i.e., about half an hour for a group of five students). The projects shall
be evaluated as per the criteria given below.

Evaluation of Dissertation Book:


Objective(s) of the work done 15 Marks
Methodology adopted 20 Marks
Results and Discussions 20 Marks
Conclusions and Outcomes 20 Marks
Total 75 Marks

Evaluation of Presentation:
Presentation of work 25 Marks
Communication skills 20 Marks
Question and answer skills 30 Marks
Total 75 Marks

Explanation: The 75 marks assigned to the dissertation book shall be same for all the students
in a group. However, the 75 marks assigned for presentation shall be awarded based on the
performance of individual students in the given criteria.
22. Industrial training (Desirable)
Every candidate shall be required to work for at least 150 hours spread over four weeks in
a Pharmaceutical Industry/Hospital. It includes production unit, Quality Control department,
Quality Assurance department, Analytical laboratory, Chemical manufacturing

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 25


unit, Pharmaceutical R&D, Hospital (Clinical Pharmacy), Clinical Research Organization,
Community Pharmacy, etc. After the Semester–VI and before the commencement of
Semester– VII, and shall submit satisfactory report of such work and certificate duly signed
by the authority of training organization to the head of the institute.
23. Practice School
In the semester-VII, every candidate shall undergo practice school for a period of 150 hours
evenly distributed throughout the semester. The student shall opt any one of the domains for
practice school declared by the program committee from time to time.
At the end of the practice school, every student shall submit a printed report (in triplicate)
on the practice school he/she attended (not more than 25 pages). Along with the exams of
Semester-VII, the report submitted by the student, knowledge and skills acquired by the
student through practice school shall be evaluated by the subject experts at college level and
grade point shall be awarded.
24. Award of Ranks
Ranks and Medals shall be awarded on the basis of final CGPA. However, candidates who
fail in one or more courses during the B. Pharm program shall not be eligible for award of
ranks. Moreover, the candidates should have completed the B. Pharm program in minimum
prescribed number of years, (four years) for the award of Ranks.
25. Award of degree
Candidates who fulfill the requirements mentioned above shall be eligible for award of
degree during the ensuing convocation.
26. Duration for completion of the program of study
The duration for the completion of the program shall be fixed as double the actual duration
of the program and the students have to pass within the said period, otherwise they have to
get fresh registration.
27. Re-admission after break of study
Candidate who seeks re-admission to the program after break of study has to get the approval
from the university by paying a condonation fee.
No condonation is allowed for the candidate who has more than 2 years of break up period
and he/she has to rejoin the program by paying the requiredfees.
28. Audit Course:
A student may have to register for an audit course in a B. Pharm which could be institute
requirement or department requirement.
An audit course may include either a) a regular course required to be done as perstructure
or required as pre-requisite of any higher level course or b) the programs like practical
training, industry visits, societal activities etc
Audit course shall not carry any credits but shall be reflected in Grade Card as "PP”/"NP"
depending upon the satisfactory performance in the semester evaluation as per the course
curriculum structure.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 26


29. Facilitation to Students:
Faculty Advisor:
On joining the institute, a student or a group of students shall be assigned to a faculty
advisor who shall be mentor for a student throughout his/her tenure in the institute. A
student shall be expected to consult the faculty advisor on any matter relating to his/her
academic performance and the courses he/she may take in various semesters/summer term.
A faculty advisor shall be the person to whom the parents/guardians should contact for
performance related issues of their ward.
The role of the Faculty Adviser is outlined below:
a) Guide the students about the rules and regulations governing the courses of study for
a particular degree.
b) Advise the students for registering courses as per curriculum given. For this purpose,
the Faculty Adviser has to discuss with the student his/her academic performance
during the previous semester and then decide the number and nature of the courses for
which He / She can register during the semester as per the curriculum.
c) Approve the registration of the students.
d) Advice students to overload/drop one or more courses/activities based on her/his
academic performance as per the prescribed rules.
e) At the end of the first semester/year, the Faculty Adviser may even advise a reduced
load program for a poorly performing student.
f) Pay special attention to weak students and carefully monitor performance of students
recommended for slow track option.
g) Advice students for Course Adjustment/Dropping of courses during the Semester
within the stipulated time frame given in the Academic calendar.
h) Advice students seeking semester drop either during the ongoing semester or before
the commencement of the semester. FA has to ensure strict compliance of rules and
regulations laid down for this purpose. Recommend the cases to the appropriate
authorities for consideration.
i) Make revised plan of study for weak/bright students based on their semester wise
performance.
j) Suggest modalities for course/credit requirements for the students recommended for
exchange program.
k) Guidance and liaison with parents of students for their performance.
l) To ensure that students are not permitted to reregister for courses, which they have
already passed.
m) Inform students that any academic activity (course/Lab/seminar/project/noncredit
requirement etc.) undergone without proper registration will not be counted towards
the requirements of his/her degree.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 27


n) Strictly warn students that if she/he fails to register during any semester without prior
approval, his/her studentship is liable to be cancelled.
o) Keep the students updated about the Academic Administration of the University.
29 .2. Helping Weaker Students:
A student with backlog/s should continuously seek help from his/her faculty advisor, Head
of the Department and the Dean of respective schools. Additionally, he/she must also be in
constant touch with his/her parents/local guardians for keeping them informed about
academic performance. The university also shall communicate to the parents/guardians of
such student at-least once during each semester regarding his/her performance in various
tests and examination and also about his/her attendance. It shallbe expected that the
parents/guardians too keep constant touch with the concerned facultyadvisor or Head of
the Department, and if necessary - the Dean of the respective school.
30. Discipline and Conduct:
 Every student shall be required to observe discipline and decorous behavior both
inside and outside the campus and not to indulge in any activity, which shall tend to
bring down the prestige of the university.
 Any act of indiscipline of a student reported to the Dean, Student Development, shall
be discussed in a Disciplinary Action Committee of the institute. The Committee
shall enquire into the charges and recommend suitable punishment ifthe charges
are substantiated.
 If a student while studying in the university is found indulging in anti-national
activities contrary to the provisions of acts and laws enforced by Government, he/she
shall be liable to be expelled from the institute without any notice.
 If a student is involved in any kind of ragging, the student shall be liable for strict
action as per provisions in the Maharashtra anti-ragging act.
 If any statement/information supplied by the student in connection with his/her
admission is found to be false/ incorrect at any time, his/ her admission shall be
cancelled and he/she shall be expelled from the university and fees paid shall be
forfeited.
 If a student is found guilty of malpractice in examinations, then he/she shall be
punished as per the recommendations of the Grievance Redressal Committee (CRC)
constituted by Board of Examinations.
 Every admitted student shall be issued photo identification (ID) card which must be
retained by the student while he/she is registered at Sanjay Ghodawat University
Kolhapur. The student must have valid ID card with him/her while in the University
Campus.
 Any student who alters or intentionally mutilates an ID card or who uses the ID card
of another student or allows his/her ID card to be used by another, studentshall
be subjected to disciplinary action.
 The valid ID card must be presented for identification purpose as and when
demanded by authorities. Any student refusing to provide an ID card shall be

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 28


subjected to disciplinary action.
 Students should switch off the Mobiles during the Instructional hours and in the
academic areas of university Building, Library, Reading room etc. Strict action will
be taken if students do not adhere to this.
 During the conduct of any Tests and Examination students must not bring their
mobiles. A student in possession of the mobile whether in use or switched off
condition will face disciplinary action and will be debarred from appearing for the
Test / Examination.
31. Academic Calendar
The academic activities of the institute are regulated by Academic Calendar and are made available
to the student’s/ faculty members and all other concerned in electronic form or hard copy. It shall
be mandatory for students / faculty to strictly adhere to the academic calendar for completion of
academic activities.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 29


2

CHAPTER - II:
SYLLABUS

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 30


Semester III
Course Name of the course No. of Tutorial Credit Internal ESE
code Hr/wk points CA SE
BP301T Pharmaceutical Organic Chemistry-II (T) 3 1 4 10 15 75
BP302T Physical Pharmaceutics-I (T) 3 1 4 10 15 75
BP303T Pharmaceutical Microbiology (T) 3 1 4 10 15 75
BP304T Pharmaceutical Engineering (T) 3 1 4 10 15 75
BP305P Pharmaceutical Organic Chemistry-II (P) 4 - 2 5 10 35
BP306P Physical Pharmaceutics-I (P) 4 - 2 5 10 35
BP307P Pharmaceutical Microbiology (P) 4 - 2 5 10 35
BP 308P Pharmaceutical Engineering (P) 4 2 5 10 35
BP105T Communication Skill (T)* 2 - 2* 5* 10* 35*
BP111P Communication Skill (P)* 2 1* 5* 5* 15*
Total 28/32* 4 24/ 27* 60/ 100/ 440/
70* 115* 490*
600/675*

* Applicable to lateral entry students only (For 3 credits)

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 31


BP301T. PHARMACEUTICAL ORGANIC CHEMISTRY–II (Theory)
45 Hours
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP301T Pharmaceutical 3 1 - 4 Theory CA 10 10
Organic (100 marks) Sessional-1 15
15 50
Chemistry–II Sessional-2 15
(Theory)
ESE 75

Scope:
This subject deals with general methods of preparation and reactions of some organic
compounds. Reactivity of organic compounds are also studied here. The syllabus
emphasizes on mechanisms and orientation of reactions. Chemistry of fats and oils are also
included in the syllabus.
Objectives:
Upon completion of this course the student should be able to
CLO1. Define, classify1 name and correctly identify various functional groups of
organiccompounds.
CLO2. Describe2 the method of preparation, reaction, its differences and orientation.
CLO3. Illustrate4 the principles/mechanisms and application of various organic
reactionsPerform
CLO4. Determine3 the analytical constant of fat and oil.
Course Content:

 General methods of preparation and reactions of compounds superscripted with asterisk


(*) to be explained.
 To emphasize on definition, types, classification, principles/mechanisms, applications,
examples and differences.
UNIT Description Hours
I Benzene and its derivatives 10
A. Analytical, synthetic and other evidences in the derivation of structure
of benzene, orbital picture, resonance in benzene, aromatic characters,
Huckel’s rule
B. Reactions of benzene- nitration, sulphonation, halogenationreactivity,
Friedelcrafts alkylation- reactivity, limitations, Friedelcrafts acylation.
C. Substituents, effect of substituents on reactivity and orientation of mono
substituted benzene compounds towards electrophilic substitution reaction
D. Structure and uses of DDT, Saccharin, BHC and Chloramine.
II Phenols*- Acidity of phenols, effect of substituents on acidity, qualitative 10
tests, Structure and uses of phenol, cresols, resorcinol, naphthols

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 32


Aromatic Amines*- Basicity of amines, effect of substituents on basicity,
and synthetic uses of aryl diazonium salts
Aromatic Acids*– Acidity, effect of substituents on acidity and important
reactions of benzoic acid.
III Fats and Oils 10
a. Fatty acids– reactions.
b. Hydrolysis, hydrogenation, Saponification and Rancidity of oils, Drying
oils.
c. Analytical constants- Acid value, Saponification value, Ester value,
Iodine value, Acetyl value, Reichert Meissl (RM) value – significance
and principle involved in their determination
IV Polynuclear hydrocarbons: 08
a. Synthesis, reactions.
b. Structure and medicinal uses of Naphthalene, Phenanthrene,
Anthracene, Diphenylmethane, Triphenylmethane and their derivatives.
V Cyclo alkanes* 07
Stabilities– Baeyer’s strain theory, limitation of Baeyer’s strain theory,
Coulson and Moffitt’s modification, Sachse Mohr’s theory (Theory of
strainless rings), reactions of cyclopropane and cyclobutane only.
Recommended Books (Latest Editions)
1. Morrison RT, Boyd RN, Bhattachargee SK. Organic Chemistry. New Delhi: Dorling
Kindersley (India) Pvt Ltd Licensees of Pearson Education.
2. Finar IL. Organic Chemistry Volume-I. Noida: Pearson Education
3. Bahl A, Bahl BS. Textbook of organic chemistry. New Delhi: S. Chand Publishing.
4. Soni PL, Chawla HM. Text book of organic Chemistry. New Delhi: Sultan Chand and
Sons Pvt Ltd.
5. Mann FG, Saunders BC. Practical Organic Chemistry. Noida: Pearson Education
6. Furniss BS, Hannaford AJ, Smith Peter WG, Tatchell AR. Vogel’s text book of
Practical Organic Chemistry. Noida: Pearson Education
7. Vishnoi NK. Advanced Practical organic chemistry. New Delhi: Vikas Publishing
House Pvt. Ltd.
8. Engel RG, Pavia DL, Lampman GM, Kriz GS. Introduction to Organic Laboratory
techniques. Brooks/Cole Publishing

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 33


BP305P. PHARMACEUTICAL ORGANIC CHEMISTRY -II (Practical)
4 Hours / week
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP305P Pharmaceutical - - 4 2 Practical CA 05 05
Organic (50 Marks) Sessional-1 10
10 50
Chemistry -II Sessional-2 10
(Practical)
ESE 35

Objectives:
Upon completion of this course the student should be able to
CLO1. Explain2 the principle involved in synthesis, purification and characterization
ofthese compounds.
CLO2. Synthesize6 purify and characterize different compounds
CLO3. Determine and Calculate3 the analytical constant of fat and oil.
CLO4. Standardize5 all reagents and calculate factors involved in the experiment
No. Description
1. Experiments involving laboratory techniques
i) Recrystallization ii) Steam distillation
2. Determination of following oil values (including standardization of reagents)
Acid value, Saponification value, Iodine value
3. Preparation of compounds.
Benzanilide/Phenyl benzoate/Acetanilide from Aniline/ Phenol /Aniline by acylation
reaction
2,4,6-Tribromo aniline/Para bromo acetanilide from Aniline
Acetanilide by halogenation (Bromination) reaction
5-Nitro salicylic acid/Meta di nitro benzene from Salicylic acid/ Nitro benzene by
nitration reaction
Benzoic acid from Benzyl chloride by oxidation reaction
Benzoic acid/ Salicylic acid from alkyl benzoate/ alkyl salicylate by hydrolysis reaction
1-Phenyl azo-2-napthol from Aniline by diazotization and coupling reactions
Benzil from Benzoin by oxidation reaction
Dibenzal acetone from Benzaldehyde by Claison Schmidt reaction
Cinnammic acid from Benzaldehyde by Perkin reaction
P-Iodo benzoic acid from P-amino benzoic acid
Recommended Books (Latest Editions)
1. Mann FG, Saunders BC. Practical Organic Chemistry. Noida: Pearson Education
2. Furniss BS, Hannaford AJ, Smith Peter WG, Tatchell AR. Vogel’s text book of
Practical Organic Chemistry. Noida: Pearson Education
3. Vishnoi NK. Advanced Practical organic chemistry. New Delhi: Vikas Publishing
House Pvt. Ltd.
4. Engel RG, Pavia DL, Lampman GM, Kriz GS. Introduction to Organic Laboratory
techniques. Brooks/Cole Publishing

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 34


BP302T. PHYSICAL PHARMACEUTICS-I (Theory)
45 Hours
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP302T Physical 3 1 - 4 Theory CA 10 10
Pharmaceutics-I (100 marks) Sessional-1 15
15 50
(Theory) Sessional-2 15
ESE 75

Scope:
The course deals with the various physical and physicochemical properties, and principles
involved in dosage forms/formulations. Theory and practical components of the subject help
the student to get a better insight into various areas of formulation research and development,
and stability studies of pharmaceutical dosage forms.
Objectives:
Upon completion of the course student shall be able to
CLO1. Describe2 fundamentals of states of matter, properties of drugs, buffers, isotonic
solutions, complexation and protein binding.
CLO2. Explain1 surface and interfacial phenomenon and applicability to biphasic
systems.
CLO3. Illustrate3 the classes of complexation and protein binding and its application
CLO4. Differentiate4 between various properties of matter and drugs.
CLO5. Apply5 concept of pH, buffer and its application to pharmaceutical and biological
systems
Course Content
UNIT Description Hours
I Solubility of drugs: Solubility expressions, mechanisms of solute solvent 10
interactions, ideal solubility parameters, solvation & association, quantitative
approach to the factors influencing solubility of drugs, diffusion principles in
biological systems. Solubility of gas in liquids, solubility of liquids in
liquids, (Binary solutions, ideal solutions) Raoult’s law, real solutions.
Partially miscible liquids, Critical solution temperature and applications.
Distribution law, its limitations and applications
II States of Matter and properties of matter: State of matter, changes in the 10
state of matter, latent heats, vapour pressure, sublimation critical point,
eutectic mixtures, gases, aerosols– inhalers, relative humidity, liquid
complexes, liquid crystals, glassy states, solidcrystalline, amorphous &
polymorphism.
Physicochemical properties of drug molecules: Refractive index, optical
rotation, dielectric constant, dipole moment, dissociation constant,
determinations and applications.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 35


III Surface and interfacial phenomenon: Liquid interface, surface & 10
interfacial tensions, surface free energy, measurement of surface &
interfacial tensions, spreading coefficient, adsorption at liquid interfaces,
surface active agents, HLB Scale, solubilisation, detergency, adsorption at
solid interface.
IV Complexation and protein binding: Introduction, classification of 08
complexation, applications, methods of analysis, protein binding,
complexation and drug action, crystalline structures of complexes and
thermodynamic treatment of stability constants.
V pH, buffers and Isotonic solutions: Sorensen’s pH scale, pH determination 07
(electrometric and calorimetric), applications of buffers, buffer equation,
buffer capacity, buffers in pharmaceutical and biological systems, buffered
isotonic solutions.

Recommended Books: (Latest Editions)


1. Martin A, Bustamante P, Chun AHC.Martin Physical Pharmacy-Physical Chemical
Principles in The Pharmaceutical Sciences. New Delhi: B. I. Waverly Pvt Ltd
2. Carter SJ. Cooper and Gunn’s Tutorial pharmacy. New Delhi: CBS Publications.
3. Stoklosa MJ, Ansel HC. Pharmaceutical Calculations. Lea & Febiger, Washington
Square, Philadelphia.
4. Liberman HA, Lachman C. Pharmaceutical Dosage forms: Tablets. Volume-1, 2, 3,
New York: Marcel Dekker
5. Liberman HA, Lachman C. Pharmaceutical Dosage forms: Disperse systems. volume
1, 2, 3. New York: Marcel Dekker.
6. Manavalan R, Ramasamy C. Physical Pharmaceutics. PharmaMed Press

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 36


BP306P. PHYSICAL PHARMACEUTICS – I (Practical)
4 Hours / Week
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP306P Physical - - 4 2 Practical CA 05 05
Pharmaceutics – I (50 marks) Sessional-1 10
10 50
(Practical) Sessional-2 10
ESE 35

Objectives:
Upon completion of the course student shall be able to
CLO1. Explain2 the terminologies in physical pharmacy, their importance, merits and
demerits
CLO2. Determine5 pka, solubility, partition coefficient and CST.
CLO3. Determine5 Surface tension, HLB, critical micellar concentration
CLO4. Determine5 Freundlich and Langmuir, complexation.
No. Description
1. Determination the solubility of drug at room temperature
2. Determination of pKa value by Half Neutralization/ Henderson Hasselbalch equation.
3. Determination of Partition co-efficient of benzoic acid in benzene and water,
Determination of Partition co-efficient of salicylic acid in chloroform and watern-
octanol and water system
4. Determination of Partition co-efficient of Iodine in CCl4 and water
5. Determination of % composition of NaCl in a solution using phenol-water system by
CST method
6. Determination of surface tension of given liquids by drop count & drop weight
method
7. Determination of HLB number of a surfactant by saponification method
8. Determination of Freundlich and Langmuir constants using activated char coal
9. Determination of critical micellar concentration of surfactants
10. Determination of stability constant and donor acceptor ratio of PABA-Caffeine
complex by solubility method
11. Determination of stability constant and donor acceptor ratio of Cupric-Glycine
complex by pH titration method
Recommended Books: (Latest Editions)
1. Subramanyam CVS, Vasantharaju SG. Laboratory Manual of Physical
Pharmaceutics.Delhi: Vallabh Prakashan.
2. Parrott EL. Saski W. Experimental pharmaceutics. Burgess Publication.
3. Stoklosa MJ, Ansel HC. Pharmaceutical Calculations. Lea & Febiger, Washington
Square, Philadelphia.
4. Carter SJ. Cooper and Gunn’s Tutorial pharmacy. New Delhi: CBS Publications.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 37


BP303T. PHARMACEUTICAL MICROBIOLOGY (Theory)
45 Hours
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP303T Pharmaceutical 3 1 - 4 Theory CA 10 10
Microbiology (100 Marks) Sessional-1 15
15 50
(Theory) Sessional -2 15
ESE 75

Scope:
Study of all categories of microorganisims especially for the production of alchol
antibiotics, vaccines, vitamins, enzymes etc.
Objectives:
Upon completion of this course the student should be able to:
CLO1. Describe2 the basic concept, classes of microorganism,
equipments/instrumentsused in microbiology.
CLO2. Explain2 methods of identification, culture, pure culture, reproduction,
cultivationand preservation of various microorganisms and cells.
CLO3. Illustrate3 sterilization and disinfection techniques, testing as per standards,
theirimportance and applications in pharmacy.
CLO4. Explain2 various sources of microbial contamination, aseptic area concept
andtechniques related to prevention of contamination
CLO5. Illustrate3 the uses of microorganisms in standardization of pharmaceuticals,
anduse of preservatives in formulations and stability evaluation.
Course Content:

UNIT Description Hours


I Introduction, history of microbiology, its branches, scope and its 10
importance.
Introduction to Prokaryotes and Eukaryotes
Study of ultra-structure and morphological classification of bacteria,
nutritional requirements, raw materials used for culture media and physical
parameters for growth, growth curve, isolation and preservation methods for
pure cultures, cultivation of anaerobes, quantitative measurement of
bacterial growth (total & viable count).
Microscopes: Study of different types of phase constrast microscopy, dark
field microscopy and electron microscopy.
Immunity, primary and secondary, defensive mechanisms of body,
microbial resistance.
II Identification of bacteria using staining techniques (simple, Gram’s & Acid 10
fast staining) and biochemical tests (IMViC).
Study of principle, procedure, merits, demerits and applications of
physical, chemical gaseous, radiation and mechanical method of

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 38


sterilization.
Evaluation of the efficiency of sterilization methods.
Equipments employed in large scale sterilization.
Sterility indicators.
III Study of morphology, classification, reproduction/replication and 10
cultivation of Fungi and Viruses.
Classification and mode of action of disinfectants
Factors influencing disinfection, antiseptics and their evaluation. For
bacteriostatic and bactericidal actions
Evaluation of bactericidal & bacteriostatic.
Sterility testing of products (solids, liquids, ophthalmic and other
sterileproducts) according to IP, BP and USP.
Air microbiology- Microorganisms in the air, sampling techniques, air
borne pathogens.
IV Designing of aseptic area, laminar flow equipments: study of different 08
sources of contamination in an aseptic area and methods of prevention,
clean area classification.
Principles and methods of different microbiological assay. Methods for
standardization of antibiotics, vitamins and amino acids.
Assessment of a new antibiotic.
V Types of spoilage, factors affecting the microbial spoilage of 07
pharmaceutical products, sources and types of microbial contaminants,
assessment of microbial contamination and spoilage.
Preservation of pharmaceutical products using antimicrobial agents,
evaluation of microbial stability of formulations.
Growth of animal cells in culture, general procedure for cell culture,
Primary, established and transformed cell cultures.
Application of cell cultures in pharmaceutical industry and research

Recommended Books: (Latest Editions)


1. Hugo WB, Russel AD. Pharmaceutical Microbiology. Blackwell Scientific publications, Oxford
London.
2. Prescott and Dunn’s Industrial Microbiology. Delhi: CBS Publishers & Distributors
3. Pelczar MJ. Chan ECS, Krieg NR. Microbiology.New Delhi: Tata McGraw Hill
4. Harris M. Pharmaceutical Microbiology. Lnondon: Balliere Tindall and Cox:
5. Rose AH. Industrial Microbiology.London: Butterworths Publication
6. Frobisher M, Hinsdill R, Crabtree KT, Goodheart CR. Fundamentals of microbiology. W B
Saunders Co.
7. Carter SJ. Cooper and Gunn’s Tutorial pharmacy. New Delhi: CBS Publications
8. Peppler HJ, Perlman D. Microbial Technology. Academic Press.
9. Ananthanarayan R. Ananthanarayan Textbook of Microbiology. Orient-Longman,Chennai
10. Jain NK. Pharmaceutical Microbiology. Delhi: Vallabh Prakashan

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 39


BP307P. PHARMACEUTICAL MICROBIOLOGY (Practical)
4 Hours / week
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP307P Pharmaceutical - - 4 2 Practical CA 05 05
Microbiology (50 Marks) Sessional-1 10
10 50
(Practical) Sessional-2 10
ESE 35
Objectives:
Upon completion of this course the student should be able to:
CLO1. Demonstrate3 the basic concept, types of microorganism and equipments/
instruments used in microbiology
CLO2. Evaluate5 microbs type, count, growth, motility, isolation, using biochemical
tests,culturing and staining techniques in microbiology.
CLO3. Measure6 the growth of microorganism in presence and absence of antibiotics.
CLO4. Perform and report6 sterility of pharmaceuticals and analysis of water.
No. Description
1. Introduction and study of different equipments and processing, e.g., B.O.D. incubator,
laminar flow, aseptic hood, autoclave, hot air sterilizer, deep freezer, refrigerator,
microscopes used in experimental microbiology.
2. Sterilization of glassware, preparation and sterilization of media.
3. Sub culturing of bacteria and fungus. Nutrient stabs and slants preparations.
4. Staining methods- Simple, Grams staining and acid fast staining (Demonstration
with practical).
5. Isolation of pure culture of micro-organisms by multiple streak plate technique and
other techniques.
6. Microbiological assay of antibiotics by cup plate method and other methods
7. Motility determination by Hanging drop method.
8. Sterility testing of pharmaceuticals
9. Bacteriological analysis of water
10. Biochemical test
Recommended Books: (Latest Editions)
1. Prescott and Dunn’s Industrial Microbiology. Delhi: CBS Publishers &Distributors
2. United State Pharmacopoeia (USP).
3. Bergey DH, Breed RS, Murray EGD, Hitchens AP Bergey's Manual of Determinative
Bacteriology. Baltimore: The Williams & Wilkins Co.
4. Anonymus. Indian pharmacopoeia. Ghaziabad: Indian Pharmacopoeia Commission
Ministry of Health & Family Welfare, Govt. of India
5. Anonymus. British pharmacopoeia. UK: The British Pharmacopoeia Commission
(BPC), The Department of Health and Social Care

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 40


BP304T. PHARMACEUTICAL ENGINEERING (Theory)
45 Hours
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP304T Pharmaceutical 3 1 - 4 Theory CA 10 10
Engineering (100 marks) Sessional-1 15
15 50
(Theory) Sessional-2 15
ESE 75

Scope:
This course is designed to impart a fundamental knowledge on the art and science of
various unit operations used in pharmaceutical industry.
Objectives:
Upon completion of course student shall be able to
CLO1. Describe2 layout designs and various unit operations of Pharmaceutical industries
CLO2. Illustrate4 principles, laws and mechanisms of operational processes in
Pharmaceutical industries.
CLO3. Summarize5 construction, working, uses, merits and demerits of equipments
usedfor size reduction, separation.
CLO4. Explain2 design, working, uses, merits and demerits of equipments used for
centrifugation, filtration, heat transfer, evaporation, and distillation
CLO5. Justify5 selection of material for pharmaceutical plant construction based on
factorsaffecting, corrosion, handing and types of material.
Course Content:
UNIT Description Hours
I Flow of fluids: Types of manometers, Reynolds number and its 10
significance, Bernoulli’s theorem and its applications, Energy losses, Orifice
meter, Venturimeter, Pitot tube and Rotometer.
Size Reduction: Objectives, Mechanisms & Laws governing size reduction,
factors affecting size reduction, principles, construction, working, uses,
merits and demerits of Hammer mill, ball mill, fluid energy mill, Edge
runner mill & end runner mill.
Size Separation: Objectives, applications & mechanism of size separation,
official standards of powders, sieves, size separation Principles,
construction, working, uses, merits and demerits of sieve shaker, cyclone
separator, air separator, bag filter & elutriation tank.
II Heat Transfer: Objectives, applications & Heat transfer mechanisms. 10
Fourier’s law, Heat transfer by conduction, convection & radiation. Heat
interchangers & heat exchangers.
Evaporation: Objectives, applications and factors influencing evaporation,
differences between evaporation and other heat process. principles,
construction, working, uses, merits and demerits of Steam jacketed kettle,
horizontal tube evaporator, climbing film evaporator, forced circulation

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 41


evaporator, multiple effect evaporator & Economy of multiple effect
evaporator.
Distillation: Basic Principles and methodology of simple distillation,flash
distillation, fractional distillation, distillation under reduced pressure, steam
distillation & molecular distillation
III Drying: Objectives, applications & mechanism of drying process, 10
measurements & applications of Equilibrium Moisture content, rate of
drying curve. Principles, construction, working, uses, merits and demerits of
Tray dryer, Drum dryer Spray dryer, Fluidized bed dryer, Vacuum dryer,
Freeze dryer.
Mixing: Objectives, applications & factors affecting mixing, Difference
between solid and liquid mixing, mechanism of solid mixing, liquids mixing
and semisolids mixing. Principles, construction, working, uses,merits and
demerits of Double cone blender, Twin shell blender, Ribbon blender, Sigma
blade mixer, Planetary mixers, Propellers, Turbines, Paddles & Silverson
Emulsifier
IV Filtration: Objectives, applications, theories & factors influencing 08
filtration, filter aids, filter medias. Principle, construction, working, uses,
merits and demerits of plate & Frame filter, Filter leaf, Rotary drum filter,
Meta filter & Cartridge filter, Membrane filters and Seidtz filter.
Centrifugation: Objectives, principle & applications of Centrifugation,
principles, construction, working, uses, merits and demerits of Perforated
basket centrifuge, Non-perforated basket centrifuge, Semi continuous
centrifuge & Super centrifuge.
V Brief introduction of layout design. 07
Materials of pharmaceutical plant construction, Corrosion and its
prevention: Factors affecting during materials selected for Pharmaceutical
plant construction, Theories of corrosion, types of corrosion and there
prevention. Ferrous and non-ferrous metals, inorganic and organic non
metals, basic of material handling systems.
Recommended Books: (Latest Editions)
1. Badger WL, Banchero JT. Introduction to chemical engineering. New York: McGraw-
Hill book company, Inc.
2. Nigel J. K. Simpson. Solid-Phase Extraction: Principles, Techniques and Applications
Dekker: New York and Basel.
3. McCabe W, Smith J, Harriott P. Unit Operations of Chemical Engineering. McGraw
Hill Education.
4. Subrahmanyam CVS, Devi KV, Sarasija S, Setty TJ. Pharmaceutical Engineering
Principles and Practices. Vallabh Prakashan.
5. Carter SJ. Cooper and Gunn’s Tutorial pharmacy. New Delhi: CBS Publications.
6. Adejare A. (Ed) Remington: The Science and Practice of Pharmacy. Academic Press
7. Khar RK, Vyas, SP, Ahmad FJ, Jain GK. Lachman Liebermans The Theory And
Practice Of Industrial Pharmacy. Delhi: CBS Publication.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 42


BP308P - PHARMACEUTICAL ENGINEERING (Practical)
4 Hours/Week
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP308P Pharmaceutical - - 4 2 Practical CA 05 05
Engineering (50 Makrs) Sessional-1 10
10 50
(Practical) Sessional-2 10
ESE 35
Objectives:
Upon completion of course student shall be able to
CLO1. Determine4 radiation constant, heat transfer, moisture constant, Loss on drying,
humidity of air.
CLO2. Analyse4 efficiency of steam distillation, uniformity index, size of granules, size
reduction, drying curve.
CLO3. Demonstrate3 Construction, working and application of pharmaceutical machinery
andequipments.
CLO4. Evaluate6 factors affecting different unit operations.
No. Description
1. Determination of radiation constant of brass, iron, unpainted and painted glass.
2. Steam distillation– To calculate the efficiency of steam distillation.
3. To determine the overall heat transfer coefficient by heat exchanger.
4. Construction of drying curves (for calcium carbonate and starch).
5. Determination of moisture content and loss on drying.
6. Determination of humidity of air– i) From wet and dry bulb temperatures –use of Dew
point method.
7. Description of Construction, working and application of pharmaceutical machinery
such as rotary tablet machine, fluidized bed coater, fluid energy mill, de humidifier
8. Size analysis by sieving– To evaluate size distribution of tablet granulations –
Construction of various size frequency curves including arithmetic and logarithmic
probability plots
9. Size reduction: To verify the laws of size reduction using ball mill and determining
Kicks, Rittinger’s, Bond’s coefficients, power requirement and critical speed of Ball
Mill.
10. Demonstration of colloid mill, planetary mixer, fluidized bed dryer, freeze dryer and
such othermajor equipment.
11. Factors affecting rate of filtration and evaporation (surface area, concentration and
thickness/ viscosity)
12. To study the effect of time on the rate of crystallization.
13. To calculate the uniformity index for given sample by using Double Cone Blender.
Recommended Books (Latest Editions)
1. McCabe W, Smith J, Harriott P. Unit Operations of Chemical Engineering. McGraw Hill
Education.
2. Carter SJ. Cooper and Gunn’s Tutorial pharmacy. New Delhi: CBS Publications.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 43


BP105RT. COMMUNICATION SKILLS (Theory)
30 Hours
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP105RT Communication 2 - - 2 Theory CA 05 05
skills (Theory) * (50 Marks) Sessional-1 10
10 50
Sessional-2 10
ESE 35

Scope:
This course will prepare the young pharmacy student to interact effectively with doctors,
nurses, dentists, physiotherapists and other health workers. At the end of this course the
student will get the soft skills set to work cohesively with the team as a team player and will
add value to the pharmaceutical business.
Objectives:
Upon completion of the course the student shall be able to
CLO1. Understand2 the behavioral needs for a pharmacist to function effectively in
theareas of pharmaceutical operation
CLO2. Communicate2 effectively (Verbal and Non Verbal)
CLO3. Perform3 effectively as team leader and team player
CLO4. Develop6 interview skills
CLO5. Develop6 Leadership qualities and essentials
Course content:

UNIT Description Hours


I Communication Skills: Introduction, Definition, The Importance of 07
Communication, The Communication Process– Source, Message,Encoding,
Channel, Decoding, Receiver, Feedback, Context
Barriers to communication: Physiological Barriers, Physical Barriers,
Cultural Barriers, Language Barriers, Gender Barriers, Interpersonal
Barriers, Psychological Barriers, Emotional barriers
Perspectives in Communication: Introduction, Visual Perception,
Language, Other factors affecting our perspective- Past Experiences,
Prejudices, Feelings, Environment
II Elements of Communication: Introduction, Face to Face Communication 07
- Tone of Voice, Body Language (Non-verbal communication), Verbal
Communication, Physical Communication
Communication Styles: Introduction, The Communication Styles Matrix
with example for each- Direct Communication Style, Spirited
Communication Style, Systematic Communication Style, Considerate

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 44


Communication Style
III Basic Listening Skills: Introduction, Self-Awareness, Active Listening, 07
Becoming an Active Listener, Listening in Difficult Situations
Effective Written Communication: Introduction, When and When Not to
Use Written Communication - Complexity of the Topic, Amount of
Discussion’ Required, Shades of Meaning, Formal Communication
Writing Effectively: Subject Lines, Put the Main Point First, Know Your
Audience, Organization of the Message
IV Interview Skills: Purpose of an interview, Do’s and Dont’s of an interview 05
Giving Presentations: Dealing with Fears, Planning your Presentation,
Structuring Your Presentation, Delivering Your Presentation, Techniques
of Delivery
V Group Discussion: Introduction, Communication skills in group 04
discussion, Do’s and Dont’s of group discussion.
Professional Conflict resolution.

Recommended Books: (Latest Edition)


1. Ruther AJ. Basic communication skills for Technology, Delhi: Pearson
Education.
2. Sanjay Kumar, Pushpa Lata. Communication skills. New Delhi: Oxford
University Press.
3. Robbins SP, Judge TA, Vohra N. Organizational Behaviour. Delhi: Pearson
Education
4. Hasson G. Brilliant communication skills. Pearson Life
5. Dalley D, Burton L, Greenhall M. Developing Your Influencing Skills: How to
Influence People by Increasing Your Credibility, Trustworthiness and
Communication Skills Universe of Learning LTD.
6. Nira K. Communication skills for professionals. New Delhi: PHI Learning
Private Limited
7. Butterfield J. Soft skill for everyone. Noida: Cengage Learning India Private
Limited
8. Francis Peters SJ. Soft skills and professional communication. Noida: McGraw-
Hill Education
9. Adair J. Effective communication. Sydney: Pan Macmillan
10. Daniels AC. Bringing out the best in people. Noida: McGraw-Hill Education.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 45


BP111P. COMMUNICATION SKILLS (Practical)
2 Hours / week
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP111P Communication -- - 2 1 Practical CA 05 05
skills – (25 Marks) Sessional-1 05
05 50
Practical* Sessional-2 05
ESE 15

Objectives:
Upon completion of the course the student shall be able to
CLO1. Communicate2 effectively using verble and nonverbal modes.
CLO2. Illustrate3 and use the different types of pronounciation.
CLO3. Comprehend2 listening and writing.
The following learning modules are to be conducted using wordsworth® English language
lab software
No. Description
1. Basic communication covering the following topics: Meeting People, Asking
Questions, Making Friends, What did you do? Do’s and Dont’s
2. Pronunciations covering the following topics: Pronunciation (Consonant Sounds)
Pronunciation and Nouns Pronunciation (Vowel Sounds)
3. Advanced Learning: Listening Comprehension / Direct and Indirect Speech Figures
of Speech, Effective Communication,
Writing Skills, Effective Writing, Interview Handling Skills, E-Mail etiquette,
Presentation Skills.
Personality development
Recommended Books: (Latest Edition)
1. Robbins SP, Judge TA, Vohra N. Organizational Behaviour. Delhi: Pearson Education
2. Hasson G. Brilliant communication skills. Pearson Life
3. Ramesh G., Ramesh M. The Ace of Soft Skills: Attitude, Communication and Etiquette
for success. Delhi: Pearson Education
4. Dalley D, Burton L, Greenhall M. Developing Your Influencing Skills: How to Influence
People by Increasing Your Credibility, Trustworthiness and Communication Skills
Universe of Learning LTD.
5. Nira K. Communication skills for professionals. New Delhi: PHI Learning Private
Limited
6. Mitra BK. Personality development and soft skills. New Delhi: Oxford University Press

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 46


Semester IV
Course Name of the course No. of Tutorial Credit Internal ESE
code hours points CA SE
BP401T Pharmaceutical Organic Chemistry III– (T) 3 1 4 10 15 75
BP402T Medicinal Chemistry I – (T) 3 1 4 10 15 75
BP403T Physical Pharmaceutics II – (T) 3 1 4 10 15 75
BP404T Pharmacology I – (T) 3 1 4 10 15 75
BP405T Pharmacognosy and Phytochemistry I– (T) 3 1 4 10 15 75
BP406P Medicinal Chemistry I – (P) 4 - 2 5 10 35
BP407P Physical Pharmaceutics II – (P) 4 - 2 5 10 35
BP408P Pharmacology I – (P) 4 2 5 10 35
BP409P Pharmacognosy and Phytochemistry I – (P) 4 - 2 5 10 35
BP205* Computer application in Pharmacy- (T)* 3* - 3* 10* 15* 50*
BP210* Computer application in Pharmacy- (P)* 2* - 1* 5* 5* 15*
BP410T Constitution of India and Professional 2 100
Ethics- (T)
Total 33/36* 5 28/ 32* 70/ 115/ 615/
85* 135* 680*
800/ 900*

* Applicable to lateral entry students only (for 4 credits)

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 47


BP401T. PHARMACEUTICAL ORGANIC CHEMISTRY –III (Theory)
45 Hours
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP401T Pharmaceutical 3 1 - 4 Theory CA 10 10
Organic Chemistry (100 Marks) Sessional-1 15
–III (Theory) 15 50
Sessional-2 15
ESE 75
Scope:
This subject imparts knowledge on stereo-chemical aspects of organic compounds and
organic reactions, important named reactions, chemistry of important hetero cyclic
compounds. It also emphasizes on medicinal and other uses of organic compounds.
Objectives:
Upon completion of the course the student shall be able to
CLO1. Define and classify1 organic compounds along with its uses.
CLO2. Draw3 three dimentional structure of stereoisomers and cyclohexane
derivativesand other organic compound.
CLO3. Identify1 different heterocyclic rings and name them.
CLO4. Illustrate4 the reactions involved in the synthesis of heterocyclic derivatives
andtheir medicinal uses.
CLO5. Explain2 applications of various reagents in synthetic reactions.
Course Content:
UNIT Description Hours
I Stereo isomerism 10
Optical isomerism –
Optical activity, enantiomerism, diastereoisomerism, meso compounds
Elements of symmetry, chiral and achiral molecules
DL system of nomenclature of optical isomers, sequence rules, RS system
of nomenclature of optical isomers
Reactions of chiral molecules
Racemic modification and resolution of racemic mixture.
Asymmetric synthesis: partial and absolute
II Geometrical isomerism 10
Nomenclature of geometrical isomers (Cis Trans, EZ, Syn Anti systems)
Methods of determination of configuration of geometrical isomers.
Conformational isomerism in Ethane, n-Butane and Cyclohexane.
Stereo isomerism in biphenyl compounds (Atropisomerism) and conditions
for optical activity.
Stereospecific and stereoselective reactions
III Heterocyclic compounds: 10
 Nomenclature and classification

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 48


 Synthesis, reactions and medicinal uses of following
compounds/derivatives-Pyrrole, Furan, and Thiophene
 Relative aromaticity and reactivity of Pyrrole, Furan and Thiophene
IV Synthesis, reactions and medicinal uses of following 10
compounds/derivatives:
 Pyrazole, Imidazole, Oxazole and Thiazole.
 Pyridine, Quinoline, Isoquinoline, Acridine and Indole. Basicity of
pyridine
Synthesis and medicinal uses of Pyrimidine, Purine, azepines and their
derivatives.
Name of the drugs containing above heterocyclic compounds (Examples)
V Reactions of synthetic importance 09
 Metal hydride reduction (NaBH4 and LiAlH4), Clemmensen reduction,
Birch reduction, Wolff Kishner reduction.
 Oppenauer-oxidation and Dakin reaction.
 Beckmanns rearrangement and Schmidt rearrangement.
 Claisen-Schmidt condensation
Recommended Books (Latest Editions)
1. Morrison RT, Boyd RN, Bhattachargee SK. Organic Chemistry. New Delhi: Dorling
Kindersley (India) Pvt Ltd Licensees of Pearson Education.
2. Finar IL. Organic Chemistry Volume-I. Noida: Pearson Education
3. Bahl A, Bahl BS. Textbook of organic chemistry. New Delhi: S. Chand Publishing.
4. Bansal RK. Heterocyclic Chemistry. New Delhi: New Age International (P) Ltd
5. Gilchrist TL. Heterocyclic Chemistry. John Wiley & Sons Inc
6. Soni PL, Chawla HM. Text book of organic Chemistry. New Delhi: Sultan Chand and
Sons Pvt Ltd.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 49


BP402T. MEDICINAL CHEMISTRY-I (Theory)
45 Hours
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP402T Medicinal 3 1 - 4 Theory CA 10 10
Chemistry- I (100 Marks) Sessional-1 15
15 50
(Theory) Sessional-2 15
ESE 75
Scope:
This subject is designed to impart fundamental knowledge on the structure, chemistry and
therapeutic value of drugs. The subject emphasizes on structure activity relationships of
drugs, importance of physicochemical properties and metabolism of drugs. The syllabus also
emphasizes on chemical synthesis of important drugs under each class.
Objectives:
Upon completion of the course the student shall be able to
CLO1. Classify1 the drugs on the basis of their chemical structure and receptor affinity.
CLO2. Illustrate4 the drug metabolic pathways and their impact on ADME and
drugactivity.
CLO3. Describe2 the chemistry of drugs Structural Activity Relationship (SAR) with
respect to their pharmacological activity.
CLO4. Summarize5 the biosynthesis and catabolism of neurotransmitters and
chemicalmodulators.
CLO5. Write3 the chemical synthesis of some drugs
Course Content
Study of the development of the following classes of drugs, Classification, mechanism of
action, uses of drugs mentioned in the course, Structure activity relationship of selective
class of drugs as specified in the course and synthesis of drugs superscripted (*)
UNIT Description Hrs
I Introduction to Medicinal Chemistry 10
History and development of medicinal chemistry
Physicochemical properties in relation to biological action
Ionization, Solubility, Partition Coefficient, Hydrogen bonding, Protein binding,
Chelation, Bioisosterism, Optical and Geometrical isomerism.
Drug metabolism: Drug metabolism principles- Phase I and Phase II.
Factors affecting drug metabolism including stereo chemical aspects.
II Drugs acting on Autonomic Nervous System 10
Adrenergic Neurotransmitters:
 Biosynthesis and catabolism of catecholamine.
 Adrenergic receptors (Alpha & Beta) and their distribution.
Sympathomimetic agents: SAR of Sympathomimetic agents
 Direct acting: Nor-epinephrine, Epinephrine, Phenylephrine*, Dopamine,

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 50


Methyldopa, Clonidine, Dobutamine, Isoproterenol, Terbutaline,
Salbutamol*, Bitolterol, Naphazoline, Oxymetazoline and Xylometazoline.
 Indirect acting agents: Hydroxyamphetamine, Pseudoephedrine,
Propylhexedrine.
 Agents with mixed mechanism: Ephedrine, Metaraminol.
Adrenergic Antagonists:
 Alpha adrenergic blockers: Tolazoline*, Phentolamine,
Phenoxybenzamine, Prazosin, Dihydroergotamine, Methysergide.
 Beta adrenergic blockers: SAR of beta blockers, Propranolol*
Metibranolol, Atenolol, Betazolol, Bisoprolol, Esmolol, Metoprolol,
Labetolol, Carvedilol.
III Cholinergic neurotransmitters: Biosynthesis and catabolism of acetylcholine. 10
Cholinergic receptors (Muscarinic & Nicotinic) and their distribution.
Parasympathomimetic agents: SAR of Parasympathomimetic agents Direct
acting agents: Acetylcholine, Carbachol*, Bethanechol, Methacholine,
Pilocarpine.
Indirect acting/ Cholinesterase inhibitors (Reversible & Irreversible):
Physostigmine, Neostigmine*, Pyridostigmine, Edrophonium chloride, Tacrine
hydrochloride, Ambenonium chloride, Isofluorphate, Echothiophate iodide,
Parathione, Malathion.
Cholinesterase reactivator: Pralidoxime chloride.
Cholinergic Blocking agents: SAR of cholinolytic agents
Solanaceous alkaloids and analogues: Atropine sulphate, Hyoscyamine
sulphate, Scopolamine hydrobromide, Homatropine hydrobromide, Ipratropium
bromide*.
Synthetic cholinergic blocking agents: Tropicamide, Cyclopentolate
hydrochloride, Clidinium bromide, Dicyclomine hydrochloride*,Glycopyrrolate,
Methantheline bromide, Propantheline bromide, Benztropine mesylate,
Orphenadrine citrate, Biperidine hydrochloride, Procyclidine hydrochloride*,
Tridihexethyl chloride, Isopropamide iodide, Ethopropazine hydrochloride.
IV Drugs acting on Central Nervous System 08
A. Sedatives and Hypnotics:
Benzodiazepines: SAR of Benzodiazepines, Chlordiazepoxide, Diazepam*,
Oxazepam, Chlorazepate, Lorazepam, Alprazolam, Zolpidem
Barbiturates: SAR of barbiturates, Barbital*, Phenobarbital, Mephobarbital,
Amobarbital, Butabarbital, Pentobarbital, Secobarbital
Miscelleneous:
Amides & imides: Glutethmide.
Alcohol & their carbamate derivatives: Meprobomate, Ethchlorvynol.
Aldehyde & their derivatives: Triclofos sodium, Paraldehyde.
B. Antipsychotics
Phenothiazeines: SAR of Phenothiazeines- Promazine hydrochloride,
Chlorpromazine hydrochloride*, Triflupromazine, Thioridazine, hydrochloride,
Piperacetazine hydrochloride, Prochlorperazine maleate, Trifluoperazine
hydrochloride.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 51


Ring Analogues of Phenothiazeines: Chlorprothixene, Thiothixene, Loxapine
succinate, Clozapine.
Fluro buterophenones: Haloperidol, Droperidol, Risperidone.
Beta amino ketones: Molindone hydrochloride.
Benzamides: Sulpieride.
C. Anticonvulsants: SAR of anticonvulsants, mechanism of anticonvulsant
action
Barbiturates: Phenobarbitone, Methabarbital.
Hydantoins: Phenytoin*, Mephenytoin, Ethotoin
Oxazolidine diones: Trimethadione, Paramethadione
Succinimides: Phensuximide, Methsuximide, Ethosuximide*
Urea and monoacylureas: Phenacemide, Carbamazepine*
Benzodiazepines: Clonazepam
Miscellaneous: Primidone, Valproic acid , Gabapentin, Felbamate
V Drugs acting on Central Nervous System 07
General anesthetics:
Inhalation anesthetics: Halothane*, Methoxyflurane, Enflurane, Sevoflurane,
Isoflurane, Desflurane.
Ultra short acting barbitutrates: Methohexital sodium*, Thiamylal sodium,
Thiopental sodium.
Dissociative anesthetics: Ketamine hydrochloride.*
Narcotic and non-narcotic analgesics
Morphine and related drugs: SAR of Morphine analogues, Morphine sulphate,
Codeine, Meperidine hydrochloride, Anilerdine hydrochloride, Diphenoxylate
hydrochloride, Loperamide hydrochloride, Fentanyl citrate*, Methadone
hydrochloride*, Propoxyphene hydrochloride, Pentazocine, Levorphanol
tartarate.
Narcotic antagonists: Nalorphine hydrochloride, Levallorphan tartarate,
Naloxone hydrochloride.
Anti-inflammatory agents: Sodium salicylate, Aspirin, Mefenamic acid*,
Meclofenamate, Indomethacin, Sulindac, Tolmetin, Zomepriac, Diclofenac,
Ketorolac, Ibuprofen*, Naproxen, Piroxicam, Phenacetin, Acetaminophen,
Antipyrine, Phenylbutazone.
Recommended Books (Latest Editions)
1. Beale JM. Block J. Wilson and Giswold’s Organic medicinal and Pharmaceutical
Chemistry. Lippincott Williams and Wilkins.
2. Williams A.D (Editor). Foye's Principles of Medicinal Chemistry. Lippincott Williams
and Wilkins.
3. Abraham DJ, Rotella DP. (Editor). Burger′s Medicinal Chemistry, Drug Discovery,
and Development. Wiley-Blackwell.
4. Smith JH, Williams H. Smith and Williams' Introduction to the Principles of Drug
Design and Action. CRC Press.
5. Final IL. Organic Chemistry, Volume 2: Stereochemistry and the Chemistry Natural
Products. Pearson Education India

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 52


BP406P. MEDICINAL CHEMISTRY-I (Practical)
4 Hours/week
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP406P Medicinal - - 4 2 Practical CA 05 05
Chemistry- I (50 Marks) Sessional-1 10
10 50
(Practical) Sessional-2 10
ESE 35
Objectives:
Upon completion of the course the student shall be able to
CLO1. Synthesize6, purify and characterize different compounds.
CLO2. Illustrate3 the principle involved in synthesis, purification and characterization
ofthese compounds.
CLO3. Evaluate6 the partition coefficient of drug.
CLO4. Analyse4 Percentage purity of drugs
No. Description
1. Preparation of drugs/ intermediates
1) 1,3-pyrazole 5) 2,3- diphenyl quinoxaline
2) 1,3-oxazole 6) Benzocaine
3) Benzimidazole 7) Phenytoin
4) Benztriazole 8) Phenothiazine
9) Barbiturate
• Recrystallization of synthesized compound.
• Identification of synthesized compounds by M.P., TLC etc
2. Assay of drugs
1) Chlorpromazine 4) Ibuprofen
2) Phenobarbitone 5) Aspirin
3) Atropine 6) Furosemide

3. Determination of Partition coefficient for any two drugs

Recommended Books (Latest Editions)


1. Adejare A. (Ed) Remington: The Science and Practice of Pharmacy. Academic Press.
2. Anonymus. Indian pharmacopoeia. Ghaziabad: Indian Pharmacopoeia Commission
Ministry of Health & Family Welfare, Govt. of India.
3. Furniss BS, Hannaford AJ, Smith Peter WG, Tatchell AR. Vogel’s text book of
Practical Organic Chemistry. Noida: Pearson Education
4. Lednicer D. The Organic Chemistry of Drug Synthesis Vol 1-5. Wiley-Blackwell.
5. Martindale W, Westcott W. Martindale: The Extra Pharmacopoeia. Pharmaceutical
Press

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 53


BP403T. PHYSICAL PHARMACEUTICS-II (Theory)
45 Hours
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP403T Physical 3 1 - 4 Theory CA 10 10
Pharmaceutics-II (100 Marks) Sessional-1 15
15 50
(Theory) Sessional-2 15
ESE 75
Scope:
The course deals with the various physical and physicochemical properties, and principles
involved in dosage forms/formulations. Theory and practical components of the subject help
the student to get a better insight into various areas of formulation research and development,
and stability studies of pharmaceutical dosage forms..
Objectives:
Upon completion of course student shall able to
CLO1. Explain2 disperse system, colloids, their properties and role in designing
dosageform.
CLO2. Differentiate4 between disperse systems, types of flow for liquids and solids,
micromeretic properties and rheological properties of formulations
CLO3. Illustrate3 micromeritics, methods of determining the same and its applications
inpharmaceutical industry
CLO4. Describe2 principle of chemical kinetics and depict expiry date of
formulationsbased on the same
CLO5. Analyze4 factors affecting stability and stabilization of dosage forms
Course Content

UNIT Description Hours


I Colloidal dispersions: Classification of dispersed systems & their general 07
characteristics, size & shapes of colloidal particles, classification of colloids
& comparative account of their general properties. Optical, kinetic &
electrical properties. Effect of electrolytes, coacervation, peptization &
protective action.
II Rheology: Newtonian systems, law of flow, kinematic viscosity, effect of 08
temperature, non-Newtonian systems, pseudoplastic, dilatant, plastic,
thixotropy, thixotropy in formulation, determination of viscosity, capillary,
falling sphere, rotational viscometers.
Deformation of solids: Plastic and elastic deformation, Heckel equation,
Stress, Strain, Elastic Modulus
III Coarse dispersion:Suspension, interfacial properties of suspended 10
particles, settling in suspensions, formulation of flocculated and

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 54


deflocculated suspensions. Emulsions and theories of emulsification,
microemulsion and multiple emulsions; Stability of emulsions, preservation
of emulsions, rheological properties of emulsions and emulsion formulation
by HLB method
IV Micromeretics: Particle size and distribution, mean particle size, number 10
and weight distribution, particle number, methods for determining particle
size by different methods, counting and separation method, particle shape,
specific surface, methods for determining surface area, permeability,
adsorption, derived properties of powders, porosity, packing arrangement,
densities, bulkiness & flow properties.
V Drug stability: Reaction kinetics: zero, pseudo-zero, first & second order, 10
units of basic rate constants, determination of reaction order. Physical and
chemical factors influencing the chemical degradation of pharmaceutical
product: temperature, solvent, ionic strength, dielectric constant, specific &
general acid base catalysis, Simple numerical problems. Stabilization of
medicinal agents against common reactions like hydrolysis & oxidation.
Accelerated stability testing in expiration dating of pharmaceutical dosage
forms. Photolytic degradation and its prevention

Recommended Books (Latest Editions)


1. Martin A, Bustamante P, Chun AHC.Martin Physical Pharmacy-Physical Chemical
Principles in The Pharmaceutical Sciences. New Delhi: B. I. Waverly Pvt Ltd
2. Carter SJ. Cooper and Gunn’s Tutorial pharmacy. New Delhi: CBS Publications.
3. Stoklosa MJ, Ansel HC. Pharmaceutical Calculations. Lea & Febiger, Washington
Square, Philadelphia.
4. Liberman HA, Lachman C. Pharmaceutical Dosage forms: Tablets. Volume-1, 2, 3,
New York: Marcel Dekker
5. Liberman HA, Lachman C. Pharmaceutical Dosage forms: Disperse systems. volume
1, 2, 3. New York: Marcel Dekker.
6. Manavalan R, Ramasamy C. Physical Pharmaceutics. PharmaMed Press

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 55


BP407P. PHYSICAL PHARMACEUTICS-II (Practical)
4 Hours / Week
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP407P Physical - - 3 2 Practical CA 05 05
Pharmaceutics- II (50 Marks) Sessional-1 10
10 50
(Practical) Sessional-2 10
ESE 35
Objectives:
Upon completion of course student shall able to
CLO1. Determine6 particle size and size distribution using various methodology and
analyze the data.
CLO2. Evaluate6 flow and related properties and interpret the data.
CLO3. Justify6 selection of viscometer for biphasic formulations.
CLO4. Determine6 shelf life of given formulations based on chemical kinetics.
No. Description
1. Determination of particle size, particle size distribution using sieving method
2. Determination of particle size, particle size distribution using microscopic method
3. Determination of bulk density, true density and porosity
4. Determine the angle of repose and influence of lubricant on angle of repose
5. Determination of viscosity of liquid using Ostwald’s viscometer
6. Determination sedimentation volume with effect of different suspending agent
7. Determination sedimentation volume with effect of different concentration of single
suspending agent
8. Determination of viscosity of semisolid by using Brookfield viscometer
9. Determination of reaction rate constant first order
10. Determination of reaction rate constant second order
11. Accelerated stability studies
Recommended Books (Latest Editions)
1. Subramanyam CVS, Vasantharaju SG. LaboratoryManual of Physical Pharmaceutics.
Delhi: Vallabh Prakashan.
2. Parrott EL. Saski W. Experimental pharmaceutics. Burgess Publication.
3. Stoklosa MJ, Ansel HC. Pharmaceutical Calculations. Lea & Febiger, Washington
Square, Philadelphia.
4. Carter SJ. Cooper and Gunn’s Tutorial pharmacy. New Delhi: CBS Publications.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 56


BP404T. PHARMACOLOGY-I (Theory)
45Hours
Course Course Title L T P C Component Exam WT Min.
Code Passing (%)
BP404T Pharmacology-I 3 1 - 4 Theory CA 10 10
(Theory) (100 Marks) Sessional-1 15
15 50
Sessional -2 15
ESE 75
Scope:
The main purpose of the subject is to understand what drugs do to the living organisms and
how their effects can be applied to therapeutics. The subject covers the information about
the drugs like, mechanism of action, physiological and biochemical effects
(pharmacodynamics) as well as absorption, distribution, metabolism and excretion
(pharmacokinetics) along with the adverse effects, clinical uses, interactions, doses,
contraindications and routes of administration of different classes of drugs.
Objectives:
Upon completion of the subject student shall be able to –
CLO1. Classify2 drugs on the basis of therapeutic use, acting on various organ systems
CLO2. Describe2 basic concepts of pharmacology, pharmacodynamics and
pharmacokinetics of drugs.
CLO3. Illustrate4 pharmacological effects, mechanism of action, indications,
contraindications and adverse effects of drugs.
CLO4. Apply3 basic pharmacological knowledge in the prevention and treatment of
various diseases.
CLO5. Explain2 steps and regulations involved in drug discovery and clinical
evaluationof new drugs.
Course content
UNIT Description Hours
I 1. General Pharmacology 08
a. Introduction to Pharmacology- Definition, historical landmarks and scope
of pharmacology, nature and source of drugs, essential drugs concept and
routes of drug administration, Agonists, antagonists (competitive and non
competitive), spare receptors, addiction, tolerance, dependence,
tachyphylaxis, idiosyncrasy, allergy.
b. Pharmacokinetics- Membrane transport, absorption, distribution,
metabolism and excretion of drugs. Enzyme induction, enzyme
inhibition, kinetics of elimination
II General Pharmacology 12
a. Pharmacodynamics- Principles and mechanisms of drug action. Receptor
theories and classification of receptors, regulation of receptors. Drug
receptors interactions signal transduction mechanisms, G-protein–

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 57


coupled receptors, ion channel receptor, transmembrane enzyme linked
receptors, spare receptors, transmembrane JAK-STAT binding receptor
and receptors that regulate transcription factors, dose response
relationship, therapeutic index, combined effects of drugs and factors
modifying drug action.
b. Adverse drug reactions.
c. Drug interactions (pharmacokinetic and pharmacodynamic)
d. Drug discovery and clinical evaluation of new drugs- Drug discovery
phase, preclinical evaluation phase, clinical trial phase, phases of clinical
trials and pharmacovigilance
III 2. Pharmacology of drugs acting on peripheral nervous system 10
a. Organization and function of ANS.
b. Neurohumoral transmission, co-transmission and classification of
neurotransmitters.
c. Parasympathomimetics, Parasympatholytics, Sympathomimetics,
Sympatholytics.
d. Neuromuscular blocking agents and skeletal muscle relaxants
(peripheral).
e. Local anesthetic agents.
f. Drugs used in myasthenia gravis and glaucoma
IV 3. Pharmacology of drugs acting on central nervous system 08
a. Neurohumoral transmission in the C.N.S. special emphasis on importance
of various neurotransmitters like with GABA, glutamate, glycine,
serotonin, dopamine.
b. General anesthetics and pre-anesthetics.
c. Sedatives, hypnotics and centrally acting muscle relaxants.
d. Anti-epileptics
e. Alcohols and disulfiram
V 3. Pharmacology of drugs acting on central nervous system 07
a. Psychopharmacological agents: Antipsychotics, antidepressants, anti-
anxiety agents, anti-manics and hallucinogens.
b. Drugs used in Parkinsons disease and Alzheimer’s disease.
c. CNS stimulants and nootropics.
d. Opioid analgesics and antagonists
e. e. Drug addiction, drug abuse, tolerance and dependence.
Recommended Books (Latest Editions)
1. Satoskar RS, Rege N, Bhandarkar SD. Pharmacology and Pharmacotherapeutics.
Elsevier India
2. Rang HP, Dale MM, Ritter JM, Flower RJ. Rang and Dale’s Pharmacology. Churchil
Livingstone Elsevier

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 58


3. Katzung BG, Masters SB, Trevor AJ. Basic and clinical pharmacology. Tata Mc Graw-
Hill
4. Marry Anne KK, Lloyd Yee Y, Brian KA, Robbin LC, Joseph G B, Wayne AK, Bradley
RW. Applied Therapeutics, The Clinical use of Drugs. Lippincott Williams &Wilkins
5. Brunton L, Chabner BA, Knollman B. Goodman and Gilman’s, The Pharmacological Basis
of Therapeutics. McGraw Hill Education
6. Mycek MJ, Gelnet SB, Perper MM. Lippincott’s Illustrated Reviews- Pharmacology.
Lippincott Williams and Wilkins
7. K.D.Tripathi. Essentials of Medical Pharmacology. JAYPEE Brothers Medical
Publishers (P) Ltd, New Delhi.
8. Sharma HL, Sharma KK. Principles of Pharmacology. Paras medical publisher.
9. Craig CR, Stitzel RE. Modern Pharmacology with clinical Applications. Lippincott
Williams and Wilkins

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 59


BP408P. PHARMACOLOGY-I (Practical)
4 Hours / Week
Course Course Title L T P C Compone Exam WT Min.
Code nt Passing (%)
BP408P Pharmacology-I - - 4 2 Practical CA 05 05
(Practical) (50 Marks) Sessional-1 10
10 50
Sessional-2 10
ESE 35

Objectives:
Upon completion of the subject student shall be able to –
CLO1. Justify6 use of animals in laboratory experiment for testing of
pharmacologicalactivities and CPCSEA guideline
CLO2. Demonstrate3 principle and procedures of various instruments /apparatus used
inexperimental pharmacology.
CLO3. Interpret6 effect of drug on animal testing model based on simulated models.
CLO4. Illustrate3 different routes of administration and common laboratory techniques
forthe animal studies
No. Description
1. Introduction to experimental pharmacology.
2. Commonly used instruments in experimental pharmacology
3. Study of common laboratory animals
4. Maintenance of laboratory animals as per CPCSEA guidelines
5. Common laboratory techniques. Blood withdrawal, serum and plasma separation
anesthetics and euthanasia used for animal studies
6. Study of different routes of drugs administration in mice/rats
7. Study of effect of hepatic microsomal enzyme inducers on the phenobarbitone sleeping
time in mice
8. Effect of drugs on ciliary motility of frog oesophagus
9. Effect of drugs on rabbit eye
10. Effects of skeletal muscle relaxants using rota-rod apparatus
11. Effect of drugs on locomotor activity using Actophotometer
12. Anticonvulsant effect of drugs byMES and PTZ method.
13. Study of stereotype and anti-catatonic activity of drugs on rats/mice..
14. Study of anxiolytic activity of drugs using rats/mice
15. Study of local anesthetics by different methods

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 60


Note: All laboratory techniques and animal experiments are demonstrated by simulated
experiments by softwares and videos

Recommended Books (Latest Editions)


1. Ghosh MN. Fundamentals of Experimental Pharmacology. Hilton & Company, Kolkata.
2. Kulkarni SK. Handbook of experimental pharmacology. Vallabh Prakashan.
3. Vogel HG, Vogel WH. Drug Discovery and Evaluation: Pharmacological Assays.
Springer-Verlag Berlin Heidelberg.
4. CPCSEA (Committee for the Purpose of Control and Supervision of Experiments on
Animals) Standard Opperating Procedures for Institutional Animal Ethics Committee
(IEAC). Animal Welfare Division, Ministry of Environment and Forest.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 61


BP405T. PHARMACOGNOSY AND PHYTOCHEMISTRY-I (Theory)
45 Hours
Course Course Title L T P C Component Exam WT Min.
Code Passing (%)
BP405T Pharmacognosy 4 1 - 4 Theory CA 10 10
And (100 Marks) Sessional-1 15
Phytochemistry-I 15 50
Sessional-2 15
(Theory)
ESE 75
Scope:
The subject involves the fundamentals of Pharmacognosy like scope, classification of crude
drugs, their identification and evaluation, phytochemicals present in them and their
medicinal properties.
Objectives:
Upon completion of the course the student shall be able to
CLO1. Describe2 the basic concepts of Pharmacognosy, sources, categories and quality
control of natural drugs and plant products
CLO2. Illustrate3 techniques in the cultivation, collection, conservation, processing
andstorage of drugs of natural origin
CLO3. Describe2 history, techniques, and application of plant tissue culture.
CLO4. Explain2 traditional medicinal therapies and primary, secondary metabolites of
crude drugs
CLO5. Distiguish4 drugs and aids of natural origin based on their biological source,
chemical nature and other pharmacognostic parameters.
Course content
UNIT Description Hours
I Introduction to Pharmacognosy: 10
a. Definition, history, scope and development of Pharmacognosy
b. Sources of Drugs – Plants, Animals, Marine & Tissue culture
c. Organized drugs, unorganized drugs (dried latex, dried juices, dried
extracts, gums and mucilages, oleoresins and oleo- gum -resins).
Classification of drugs: Alphabetical, morphological, taxonomical,
chemical, pharmacological, chemo and sero taxonomical classification of
drugs
Quality control of Drugs of Natural Origin: Adulteration of drugs of
natural origin. Evaluation by organoleptic, microscopic, physical, chemical
and biological methods and properties.
Quantitative microscopy of crude drugs including lycopodium spore method,
leafconstants, camera lucida and diagrams of microscopic objects to scale
with camera lucida.
II Cultivation, Collection, Processing and storage of drugs of natural 10
origin:

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 62


Cultivation and Collection of drugs of natural origin
Factors influencing cultivation of medicinal plants.
Plant hormones and their applications.
Polyploidy, mutation and hybridization with reference to medicinal plants
Conservation of medicinal plants
III Plant tissue culture: Historical development of plant tissue culture, types 07
of cultures, Nutritional requirements, growth and their maintenance.
Applications of plant tissue culture in pharmacognosy. Edible vaccines
IV Pharmacognosy in various systems of medicine: 10
Role of Pharmacognosy in allopathy and traditional systems of medicine
namely, Ayurveda, Unani, Siddha, Homeopathy and Chinese systems of
medicine.
Introduction to secondary metabolites: Definition, classification,
properties and test for identification of Alkaloids, Glycosides, Flavonoids,
Tannins, Volatile oil and Resins
V Study of biological source, chemical nature and uses of drugs of 08
natural origin containing following drugs
Plant Products:
Fibers - Cotton, Jute, Hemp
Hallucinogens, Teratogens, Natural allergens
Primary metabolites:
General introduction, detailed study with respect to chemistry, sources,
preparation, evaluation, preservation, storage, therapeutic used and
commercial utility as Pharmaceutical
Aids and/or Medicines for the following Primary
metabolites:Carbohydrates: Acacia, Agar, Tragacanth, Honey
Proteins and Enzymes: Gelatin, Casein, proteolytic enzymes (Papain,
bromelain, serratiopeptidase, urokinase, streptokinase, pepsin).
Lipids (Waxes, fats, fixed oils): Castor oil, Chaulmoogra oil, Wool Fat,
Bees Wax
Marine Drugs: Novel medicinal agents from marine sources
Recommended books (Latest edition):
1. Evans WC. Trease and Evans Pharmacognosy. W.B. Sounders & Co., London, 2009.
2. Tyler VE, Brady LR, Robbers JE. Pharmacognosy Lea and Febiger, Philadelphia,
3. Wallis TE. Text Book of Pharmacognosy. New Delhi: CBS Publication.
4. Mohammad Ali. Pharmacognosy and Phytochemistry. New Delhi: CBS Publishers &
Distribution,.
5. Kokate CK, Purohit AP, Gokhlae SB. Text book of Pharmacognosy. New Delhi: Nirali
Prakashan,.
6. Choudhary RD, Chopra RD. Herbal drug industry:A Practical Approach to Industrial
Pharmacognosy. New Delhi: Eastern Publisher.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 63


BP409P. PHARMACOGNOSY AND PHYTOCHEMISTRY-I (Practical)
4 Hours/week
Course Course Title L T P C Component Exam WT Min.
Code Passing (%)
BP409P Pharmacognosy - - 2 1 Practical CA 05 05
And (50 Marks) Sessional-1 10
Phytochemistry- I 10 50
Sessional-2 10
(Practical)
ESE 35
Objectives:
Upon completion of the course the student shall be able to
CLO1. Determine6 microscopic and morphological characteristics of crude drugs.
CLO2. Analyze4 crude drugs by qualitative parameters
CLO3. Analyze4 crude drugs by quantitative parameters
CLO4. Describe2 evaluation techniques for herbal drugs

No. Description
1. Analysis of crude drugs by chemical tests: (i)Tragaccanth (ii) Acacia (iii)Agar (iv)
Gelatin (v) starch (vi) Honey (vii) Castor oil
2. 2. Determination of stomatal number and index
3. 3. Determination of vein islet number, vein islet termination and paliside ratio
4. 4. Determination of size of starch grains, calcium oxalate crystals by eye piece
micrometer
5. 5. Determination of Fiber length and width
6. 6. Determination of number of starch grains by Lycopodium spore method
7. 7. Determination of Ash value
8. 8. Determination of Extractive values of crude drugs
9. 9. Determination of moisture content of crude drugs
10. 10. Determination of swelling index and foaming

Recommended books (Latest edition):


1. Gokhale SB, Kokate CK. Practical Pharmacognosy.Nirali Prakashan
2. Iyengar MA. Anatomy of Crude Drugs. PharmaMed Press
3. Khandelwal KR. Practical Pharmacognosy. Nirali Prakashan.
4. Quality Control Methods for Herbal Material. World Health Organisation. 2011

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 64


BP205RT. COMPUTER APPLICATIONS IN PHARMACY (Theory)
30 Hrs (2 Hrs/Week)
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP205RT Computer 3 - - 3 Theory CA 10 10
Applications in (75 Marks) Sessional-1 15
Pharmacy 15 5
Sessional-2 15 0
(Theory) *
ESE 50
Scope:
This subject deals with the introduction Database, Database Management system,
computer application in clinical studies and use of databases.
Objectives:
Upon completion of the course the student shall be able to
CLO1. Describe2 various systems of computer applications and web technologies
CLO2. Explain2 various types of databases and applications of computer in pharmacy
CLO3. Illustrate3 bioinformatics and utilization of various data basis in preclinical
development.
CLO4. Create6 web page an databases using relevant computer programs.
Course content
UNIT Description Hours
I Number system: Binary number system, Decimal number system, Octal 06
number system, Hexadecimal number systems, conversion decimal to
binary, binary to decimal, octal to binary etc, binary addition, binary
subtraction – One’s complement ,Two’s complement method, binary
multiplication, binary division
Concept of Information Systems and Software : Information gathering,
requirement and feasibility analysis, data flow diagrams, process
specifications, input/output design, process life cycle, planning and
managing the project
II Web technologies: Introduction to HTML, XML, CSS and Programming 06
languages, introduction to web servers and Server Products. Introduction
to databases, MYSQL, MS ACCESS, Pharmacy Drug database
III Application of computers in Pharmacy – Drug information storage and 06
retrieval, Pharmacokinetics, Mathematical model in Drug design, Hospital
and Clinical Pharmacy, Electronic Prescribing and discharge (EP) systems,
barcode medicine identification and automated dispensing ofdrugs, mobile
technology and adherence monitoring.
Diagnostic System, Lab-diagnostic System, Patient Monitoring System,
Pharma Information System

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 65


IV Bioinformatics: Introduction, Objective of Bioinformatics, 06
Bioinformatics Databases, Concept of Bioinformatics, Impact of
Bioinformatics in Vaccine Discovery
V Computers as data analysis in Preclinical development: 06
Chromatographic dada analysis(CDS), Laboratory Information
management System (LIMS) and Text Information Management
System(TIMS)
Recommended books (Latest edition):
1. Fassett WE, Christensen DB, editors, Campbell WH, Koup JR, Malone PM. Computer
Application in Pharmacy Philadelphia, PA : Lea & Febiger.
2. Ekins S, editor. Computer Application in Pharmaceutical Research and Development.
New Jersey: Wiley-Interscience, A John Willey and Sons, INC., Publication.
3. Rastogi SC, Mendiratta N, Rastogi P. Bioinformatics Concept, Skills and Applications.
New Delhi: CBS Publishersand Distributors.
4. Microsoft office Access -2003, Application Development Using VBA, SQL Server, AP and
Infopath –Cary N.Prague – Wiley Dreamtech India (P) Ltd., 4435/7, Ansari Road,
Daryagani, New Delhi – 110002

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 66


BP210RP. COMPUTER APPLICATIONS IN PHARMACY (Practical)
Course Course Title L T P C Component Exam WT Passing
Code Min. (%)
BP210RP Computer - - 2 1 Practical CA 05 05
Applications in (25 Marks) Sessional-1 05
05 50
Pharmacy Sessional-2 05
(Practical)*
ESE 15
Objectives:
Upon completion of the course the student shall be able to
CLO1. Create6 web page an databases using relevant computer programs.
CLO2. Design6 the documents of pharmaceutical importance using suitable computer
program.
CLO3. Demonstrate3 exporting of various data to web and XML format.
CLO4. Demonstrate3 medical coding and modeling of chemical structre.
No. Description
1. Design a questionnaire using a word processing package to gather information abouta
particular disease.
2. Create a HTML web page to show personal information
3. Retrieve the information of a drug and its adverse effects using online tools
4. Creating mailing labels Using Label Wizard , generating label in MS WORD
5. Create a database in MS Access to store the patient information with therequiredfields
Using access
6. Design a form in MS Access to view, add, delete and modify the patient recordinthe
database
7. Generating report and printing the report from patient database
8. Creating invoice table using – MS Access
9. Drug information storage and retrieval using MS Access
10. Creating and working with queries in MS Access
11. Exporting Tables, Queries, Forms and Reports to web pages
12. Exporting Tables, Queries, Forms and Reports to XML pages
13. Medical coding
14. Modeling of chemical structures
Recommended books (Latest edition):
1. Fassett WE, Christensen DB, editors, Campbell WH, Koup JR, Malone PM. Computer
Application in Pharmacy Philadelphia, PA : Lea & Febiger.
2. Ekins S, editor. Computer Application in Pharmaceutical Research and
Development. New Jersey: Wiley-Inter-science, A John Willey and Sons, INC..
3. Microsoft office Access -2003, Application Development Using VBA, SQLServer, AP
and Infopath –Cary N. Prague – Wiley Dreamtech India (P) Ltd., 4435/7, Ansari Road,
Daryagani, New Delhi – 110002

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 67


BP211T.CONSTITUTION OF INDIA AND PROFESSIONAL ETHICS-(THEORY)

Course Course Title L T P C Component Exam WT Passing


Code Min. (%)
BP211T Constitution of India 2 - - - Theory CA - -
and Professional (100 Marks) Sessional-1 -
- 40
Ethics (Theory) Sessional-2 -
ESE 100

Course Outcomes:
After the end of this course students will be able to
CLO1: Illustrate3 state and central policies, fundamental duties, Union and State Executives
CLO2: Explain2 special provisions, emergency provisions, Human rights, Panchayat Raj.
CLO3: Apply5 Ethics and Responsibility of a pharmacist in the practice
CLO4: Appraise6 code of ethics for a Pharmacy.

Course content
UNIT Description

I Historical Background and The Making of the Indian Constitution Salient Features
of the Indian Constitution, Fundamental Rights, Fundamental Duties, Directive
Principles of State Policy & Relevance of Directive Principles State Policy.
Fundamental Duties. Union Executives: President, Prime Minister Parliament
Supreme Court of India. State Executives: Governor Chief Minister, State
Legislature High Court of State. Electoral Process in India, Amendment Procedures,
42nd, 44th, 74th, 76th, 86th & 91st Amendments. The Indian Judiciary System.
II Special Provision for SC & ST Special Provision for Women, Children & Backward
Classes. Emergency Provisions. Human Rights –Meaning and Definitions,
Legislation Specific Themes in Human Rights- Working of National Human Rights
Commission in India. Powers and functions of Municipalities, Panchyats and Co -
Operative Societies.

III Introduction to pharmacy act 1948 and amendments thereafter, Code of Ethics
for Pharmacy

Recommended Books (Latest edition):


1. Reddy GB, Suhaib M. Constitution of India and Professional Ethics, I.K. International
Publishing House Pvt. Limited, 2010
2. Pylee MV. “An Introduction to Constitution of India”, Vikas Publishing.

Rules and Syllabus for S. Y. B. Pharm course 2023-24 Page 68

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