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    Case Study

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    case study pharma

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    Case Study

    Uploaded by

    khatadiadhaval
    1 views7 pages
    case study pharma

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    © © All Rights Reserved

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    case study pharma

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    1 views7 pages

    Case Study

    Uploaded by

    khatadiadhaval
    case study pharma

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 7

    CASE STUDY

    GAS, LIQUID & PHARMA FILTRATION


    Case Study (FBD Bag)
    H.E. Advanced Nutrition SA

    • Equipment → GEA Aereomatic.


    • Testori filter → Fluid bed bag diameter 1800 mm with 61
    sleeves.
    • Application → Granulation and drying.
    • Failure Analysis → The Bag life achieved was 9-10
    batches as the bag was tearing off at the flange and cap.
    • Solutions → We are offering a fluid bed bag with
    reinforced flange and caps. Moreover, the different size of
    the bags allow an easier fitting and an increased lifetime.
    • Improvement → Increasing in filter life to 19 batches
    which is >90% increase.

    Confidential information and for internal use only 2


    Property of Testori Group – duplication prohibited
    Case Study (FBD Bag)
    JANSSEN - Cilag Puebla plant (Mexico)

    • Equipment → GLATT WSG 20


    • Testori filter → LIFEtes fabric quality Fluid bed bag
    diameter 1330 mm with 42 sleeves
    • Application → drying of fine powder.
    • Failure Analysis → The competition fabric had bigger
    pore side and hence there was product loss.
    • Solutions → Testori offered thermos welded sleeve,
    double caps and a closer fabric (lower pore size)
    • Improvement → Reduction in product loss by >25%

    Confidential information and for internal use only 3


    Property of Testori Group – duplication prohibited
    Case Study (Centrifuge)
    Flamma (Chignolo D’Isola- BG)
    • Product and process analysis → API in water and methanol solution
    with a small residue of hydrogen peroxide (oxidant)

    • Problem analysis → During centrifugation the product tends to form


    very hard blocks. Originally this product was processed on an
    extractable bag centrifuge, however the customer needed to change to
    an invertible bag centrifuge (Comi Condor HT/GMP 700/225)

    • Competition product analysis → the customer had already carried out


    tests with a Sefar product and was not satisfied. Analysis on new
    recovered sample (REC 262 of 2019)

    • Solution → our proposed optimized solution increased the filter lifetime


    for the number of processed batches (from 2/3 to 8 batches) with
    centrifuge bag in P 2512 TQ (7EZC017APF80)
    Confidential information and for internal use only 4
    Property of Testori Group – duplication prohibited
    Case Study (Centrifuge)
    Flamma (Chignolo D’Isola- BG)

    Filter in PP mono filament fabric. Filter in PP multi filament fabric.


    Bag life achieved was for 2-3 batches Bag life achieved was for 8 batches, which is
    300 % increase in bag life.
    Failure due to premature breakage of the bag Extension of the lifetime (tripled) of the filter
    caused by the hard blocks of product which cut with important savings for the customer
    the fabric when the bag was inverted (product, cost and time)

    Confidential information and for internal use only 5


    Property of Testori Group – duplication prohibited
    Case Study (Pulse Jet bag)
    International Dry Products - Mexico

    • Product and process analysis → drying of corn starch for pharma and
    food applications with Anhydro dryer and AISI steel collector.

    • Problem analysis → the customer received a major complaint for


    product contamination by polyester fibers in all the delivered batches.

    • Competition product analysis → filter sleeves in polyester felt


    d. 125 x 3110 mm – snap ring and reinforced bottom.

    • Solution → our proposal for improvement with change of the filter


    media to fabric and LIFEtes fabrication: LIFEtes sleeves in TW 6615 TB
    (7ASG255.LT01).

    Confidential information and for internal use only 6


    Property of Testori Group – duplication prohibited
    Case
    Case Study
    Study (Pulse
    (Pulse Jet
    Jet bag)
    bag)
    International Dry Products - Mexico
    As a main result the contamination with textile fibers could be eliminated. The customer
    appreciated the following important improvements which also resulted of the proposed
    solution:

    1. Stopping product leakage through the filters


    2. Savings in cleaning air by programming of the cleaning cycle and the very smooth surface of
    the fabric which allows excellent release of the product cake
    3. Complete LIFEtes quality documentation highly appreciated for easy use with the
    authorities.
    4. The customer has signed a long term contract for the supply of out Testori LIFEtes filter
    solution.

    Confidential information and for internal use only 7


    Property of Testori Group – duplication prohibited

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