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    Stem Cell Technology: Michael L. Villavert BSN 33 Batch

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    Michael Villavert
    This document provides an overview of stem cell technology. It defines stem cells as cells that can differentiate into other cell types and have the potential to treat many diseases. The history of stem cell research began in the 1960s with the discovery of stem cells in mice. There are several types of stem cells ranging from totipotent to unipotent. Stem cells may treat diseases through differentiation and regeneration of cells/tissues. Recent advances show promise for treating conditions like ALS, Alzheimer's, blindness and many others. However, issues around cancer risk, tissue rejection and ethics require further study.

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    Stem Cell Technology: Michael L. Villavert BSN 33 Batch

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    Michael Villavert
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    This document provides an overview of stem cell technology. It defines stem cells as cells that can differentiate into other cell types and have the potential to treat many diseases. The history of stem cell research began in the 1960s with the discovery of stem cells in mice. There are several types of stem cells ranging from totipotent to unipotent. Stem cells may treat diseases through differentiation and regeneration of cells/tissues. Recent advances show promise for treating conditions like ALS, Alzheimer's, blindness and many others. However, issues around cancer risk, tissue rejection and ethics require further study.

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    This document provides an overview of stem cell technology. It defines stem cells as cells that can differentiate into other cell types and have the potential to treat many diseases. The history of stem cell research began in the 1960s with the discovery of stem cells in mice. There are several types of stem cells ranging from totipotent to unipotent. Stem cells may treat diseases through differentiation and regeneration of cells/tissues. Recent advances show promise for treating conditions like ALS, Alzheimer's, blindness and many others. However, issues around cancer risk, tissue rejection and ethics require further study.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    100 views17 pages

    Stem Cell Technology: Michael L. Villavert BSN 33 Batch

    Uploaded by

    Michael Villavert
    This document provides an overview of stem cell technology. It defines stem cells as cells that can differentiate into other cell types and have the potential to treat many diseases. The history of stem cell research began in the 1960s with the discovery of stem cells in mice. There are several types of stem cells ranging from totipotent to unipotent. Stem cells may treat diseases through differentiation and regeneration of cells/tissues. Recent advances show promise for treating conditions like ALS, Alzheimer's, blindness and many others. However, issues around cancer risk, tissue rejection and ethics require further study.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 17

    STEM CELL TECHNOLOGY

    Michael L. Villavert BSN 33rd Batch

    Objectives
    To know and describe what stem cells are. To know what stem cell technology is. To know the different types of stem cells. To know how stem cells originated and how it was discovered. To know the recent advances involving stem cells.

    Stem Cell Technology


    a rapidly developing field that combines the efforts of cell biologists, geneticists, and clinicians and offers hope of effective treatment for a variety of malignant and non-malignant diseases a field of medical research studying human and animal stem cells

    What are stem cells???


    Stem cells are cells without specific structure that may give rise to other kinds of cells. If allowed to reach their full potential, they could be used to treat and cure various diseases and conditions.

    History
    The origination of stem cell research must mention the studies of Dr. Ernest Armstrong McCulloch and Dr. James Edgar Till during the early 1960s (1). These Canadian physician scientists were studying mouse hematopoiesis (blood formation) and identified cells that when transplanted into irradiated mice would give rise to individual cellular colonies on the host spleen. Microscopically, these colonies underwent self-renewal and were differentiating into three different cell lines:
    erythrocytes (red blood cells), granulocytes megakaryocytes.

    History
    These results supported the Unitarian Theory of Hematopoiesis, a hypothesis proposed by a Russian scientist, Alexander A. Maximov, over 50 years earlier, and were heralded as the discovery of stem cells.

    Types of Stem Cells


    Totipotent
    "total power" stem cells that can differentiate into any cell types.

    Types of Stem Cells


    Pluripotent
    stem cells that can form any cell type (e.g. embryonic stem cells) EXCEPT extraembryonic cells (i.e. those outside the embryo).

    Types of Stem Cells


    Multipotent
    have the power to differentiate into cells in the same family of cells (e.g. hematopoietic stem cell).

    Types of Stem Cells


    Oligopotent
    stem cells may only differentiate into a subset of cells in a particular family (e.g. lymphoid or myeloid stem cells).

    Types of Stem Cells


    Unipotent
    cells perform selfrenewal and are committed to a single cell type (e.g. hepatocytes).

    How exactly do Stem Cells Treat Diseases?


    Stem cells could be used to treat diseases because of their ability to become different types of cells. The extent of stem cells' abilities to treat and cure diseases has not yet been fully discovered, and there is still much work to be done so that they may reach their full potential.

    Stem Cell Advances


    ALS (Lou Gehrigs Disease) Alzheimers Disease Blindness Blood Disorders Blood Supply Brain Tumors

    Stem Cell Advances


    Cancer Cartilage Damage Diabetes Hearing Loss Heart Disease & Damage Infertility Lung Damage

    Stem Cell Advances


    Multiple Sclerosis Muscular Dystrophy Organ Replacement Parkinsons Disease Platelet Transfusions Spinal Cord Injury Tissue Damage

    Issues
    Stem cell as cancer cells Tissue rejection Use of adult stem cells from other part of the body Human stem cells from embryos

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