34 Circulation

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Figure 34.

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Figure 34.2

Mouth

Gastrovascular
cavity

1 mm

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Figure 34.4

(a) Single circulation: fish

Gill capillaries

(b) Double circulation:


amphibian

Vein

Pulmonary
circuit

Pulmocutaneous
circuit
Lung
and skin
capillaries

Artery
Heart:
Atrium (A)
Ventricle (V)

(c) Double circulation:


mammal

A
Right

Lung
capillaries

A
V

A
Left

Right

A
V
Left

Systemic
capillaries
Body capillaries
Key
Oxygen-rich blood
Oxygen-poor blood

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Systemic circuit

Systemic
capillaries
Systemic circuit

Figure 34.4a

(a) Single circulation: fish

Gill capillaries

Artery
Heart:
Atrium (A)
Ventricle (V)
Vein

Body capillaries
Key
Oxygen-rich blood
Oxygen-poor blood
2014 Pearson Education, Inc.

Figure 34.4b

(b) Double circulation:


amphibian
Pulmocutaneous
circuit
Lung
and skin
capillaries

A
Right

A
Left
V
Systemic
capillaries

Systemic circuit
Key
Oxygen-rich blood
Oxygen-poor blood
2014 Pearson Education, Inc.

Figure 34.4c

(c) Double circulation:


mammal
Pulmonary
circuit
Lung
capillaries

A
V
Right

A
V
Left
Systemic
capillaries

Systemic circuit
Key
Oxygen-rich blood
Oxygen-poor blood
2014 Pearson Education, Inc.

Figure 34.5

Superior
vena cava

Capillaries of
head and
forelimbs

Pulmonary
artery
Capillaries
of right lung

Pulmonary artery
Capillaries
of left lung

Aorta

6
2

4
11

Pulmonary
vein
Right atrium

Pulmonary
vein
Left atrium

10

Left ventricle

Right ventricle
Inferior vena cava

Aorta

8
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Capillaries of
abdominal organs
and hind limbs

Figure 34.6

Aorta

Pulmonary artery

Pulmonary
artery
Right
atrium

Left
atrium

Semilunar
valve

Semilunar
valve

Atrioventricular
(AV) valve

Atrioventricular
(AV) valve

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Right
ventricle

Left
ventricle

Figure 34.9

LM

Artery Vein

Red blood
cells

100 m

Valve

Basal lamina

Endothelium
Smooth
muscle

Connective
tissue

Endothelium
Smooth
muscle

Artery

Vein

Capillary

15 m

Red blood cell

Venule

LM

Arteriole

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Connective
tissue

Capillary

Figure 34.9a

Valve
Connective
tissue

Endothelium

Basal lamina

Smooth
muscle

Smooth
muscle

Capillary

Endothelium

Artery

Vein

Arteriole

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Venule

Connective
tissue

Figure 34.9b

LM

Artery Vein

Red blood
cells

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100 m

Capillary

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LM

Red blood cell

15 m

Figure 34.9c

Figure 34.11

Direction of blood
flow in vein
(toward heart)

Valve (open)

Skeletal muscle

Valve (closed)

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Figure 34.13

Cellular elements 45%

Plasma 55%
Constituent
Water

Ions (blood
electrolytes)
Sodium
Potassium
Calcium
Magnesium
Chloride
Bicarbonate

Major functions
Solvent for
carrying other
substances
Osmotic balance,
pH buffering,
and regulation
of membrane
permeability

Leukocytes (white blood cells)


Separated
blood
elements

per L (mm3)
of blood

Functions

5,00010,000

Defense
and
immunity

Lymphocytes

Basophils

Eosinophils

Plasma proteins

Neutrophils

Albumin

Osmotic balance,
pH buffering

Fibrinogen

Clotting

Immunoglobulins
(antibodies)

Defense

Substances transported by blood


Nutrients (such as glucose, fatty
acids, vitamins)
Waste products of metabolism
Respiratory gases (O2 and CO2)
Hormones

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Number

Cell type

Monocytes

Platelets

Erythrocytes (red blood cells)

250,000400,000

5,000,000
6,000,000

Blood
clotting
Transport
of O2 and
some CO2

Figure 34.13a

Plasma 55%
Major functions

Constituent
Water

Solvent for carrying other


substances

Ions (blood electrolytes)


Sodium
Potassium
Calcium
Magnesium
Chloride
Bicarbonate

Osmotic balance, pH buffering,


and regulation of membrane
permeability

Plasma proteins
Albumin

Osmotic balance, pH buffering

Fibrinogen

Clotting

Immunoglobulins
(antibodies)

Defense

Substances transported by blood


Nutrients (such as glucose, fatty acids, vitamins)
Waste products of metabolism
Respiratory gases (O2 and CO2)
Hormones
2014 Pearson Education, Inc.

Figure 34.13b

Cellular elements 45%


Number

Cell type

per L (mm3) of blood

Leukocytes (white blood cells)

Basophils

5,00010,000

Functions
Defense and
immunity

Lymphocytes

Eosinophils

Neutrophils

Monocytes

Platelets

Erythrocytes (red blood cells)

2014 Pearson Education, Inc.

250,000400,000

5,000,0006,000,000

Blood clotting

Transport of O2 and
some CO2

Figure 34.14

Stem cells
(in bone marrow)

Lymphoid
stem cells

Myeloid
stem cells

B cells T cells

Erythrocytes
Lymphocytes

Monocytes

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Neutrophils

Platelets

Basophils

Eosinophils

Figure 34.20

Branch of
pulmonary vein
(oxygen-rich
blood)

Branch of pulmonary
artery (oxygen-poor
blood)

Terminal
bronchiole
Nasal
cavity
Pharynx
Left
lung

Larynx
(Esophagus)

Alveoli

Trachea
Right lung
Capillaries

Bronchus

50 m

Bronchiole
Diaphragm
(Heart)
Dense capillary bed
enveloping alveoli
(SEM)
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Figure 34.20a

Nasal
cavity
Pharynx
Left
lung

Larynx
(Esophagus)
Trachea
Right lung
Bronchus
Bronchiole
Diaphragm
(Heart)
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Figure 34.20b

Branch of
pulmonary vein
(oxygen-rich
blood)

Branch of pulmonary
artery (oxygen-poor
blood)

Terminal
bronchiole

Alveoli
Capillaries

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Figure 34.20c

50 m

Dense capillary bed


enveloping alveoli (SEM)

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Figure 34.22

Rib cage
expands as
rib muscles
contract.

Air
inhaled.

Rib cage gets


smaller as
rib muscles
relax.

Air
exhaled.

Lung
Diaphragm

1 Inhalation:
Diaphragm contracts
(moves down).

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2 Exhalation:
Diaphragm relaxes
(moves up).

Figure 34.23-1

Homeostasis:
Blood pH of about 7.4

Stimulus:
Rising level of CO2
in tissues lowers
blood pH.

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Figure 34.23-2

Homeostasis:
Blood pH of about 7.4

Stimulus:
Rising level of CO2
in tissues lowers
blood pH.

Carotid
arteries
Sensor/control
center:
Cerebrospinal
fluid
Medulla
oblongata
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Aorta

Figure 34.23-3

Homeostasis:
Blood pH of about 7.4

Response:
Signals from
medulla to rib
muscles and
diaphragm
increase rate
and depth of
ventilation.

Stimulus:
Rising level of CO2
in tissues lowers
blood pH.

Carotid
arteries
Sensor/control
center:
Cerebrospinal
fluid
Medulla
oblongata

2014 Pearson Education, Inc.

Aorta

Figure 34.24
120 27

Inhaled air

Exhaled air

160 0.2

O2 CO2

O2 CO2

Alveolar
epithelial
cells

CO2

O2

Alveolar
spaces
Alveolar
capillaries
Pulmonary
veins

Pulmonary
arteries
40 45

104 40

O2 CO2

O2 CO2

Systemic
veins

Systemic
arteries

Systemic
capillaries

Heart

CO2

O2

<40 >45

O2 CO2

Body tissue
cells
2014 Pearson Education, Inc.

Figure 34.UN03

Inhaled air

Exhaled air
Alveolar
epithelial
cells

Alveolar
spaces
CO2

O2
Alveolar
capillaries

Pulmonary
arteries

Pulmonary
veins

Systemic
veins

Systemic
arteries

Heart

CO2

O2

Systemic
capillaries
Body tissue

2014 Pearson Education, Inc.

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