DYSPNEA (Shortness of Breath)
DYSPNEA (Shortness of Breath)
DYSPNEA (Shortness of Breath)
Dyspnea results from abnormalities of gas exchange (decreased oxygenation, hypoventilation, hyperventilation), and
increased work of breathing because of changes in respiratory mechanics and/or anxiety
Clinical occurrence
Paroxysmal dyspnea.
A transient increase in pulmonary capillary pressure is caused by redistribution of fluid from edematous extremities to the
lungs with recumbency, or ischemia-induced transient decreases in LV performance. Sudden paroxysms of breathlessness
often occur with recumbency or exertion. When sleep is interrupted, it is termed paroxysmal nocturnal dyspnea which
may be accompanied by orthopnea and coughing. The patient often finds that sitting or walking for a few minutes relieves
the dyspnea permitting sleep to resume.
Redistribution of extracellular fluid from the periphery to the lungs, elevation of the diaphragm from obesity or ascites,
and muscular weakness all contribute to dyspnea when lying flat. The patient assumes a resting position with the head
and chest elevated; the severity is estimated by the number of pillows required to achieve a comfortable sleeping position.
Many patients awaken from sleep in the supine position severely short of breath (paroxysmal nocturnal dyspnea).
Orthopnea may be overlooked if not specifically ask about or if the patient is not observed for some time while supine.
Enlargement of pulmonary arteriovenous shunts leads to increased right to left shunting with standing. The results are
decreased oxygen saturation on standing (orthodeoxia) and shortness of breath. This is part of the hepatopulmonary
syndrome seen in patients with advanced liver disease. Patients complain of shortness of breath and weakness on
standing, relieved by sitting or lying. They have stigmata of advanced liver disease including cutaneous spiders and ascites
caused by portal hypertension.