QuadroStarPRO Presentation PDF

QuadroStarPRO Family
- 577, 532, 940 & 980 nm Laser -

Technology „Made in Germany“
For more than 35 years, Asclepion has been operating on the medical laser
market. As the company is based in Jena, famous through the world as the
global center of the optics industry since 1846, the company owes it success
to the steady development of new technologies and the active collaboration
with researchers from German universities and industries.
• More than 35 years experience in the aesthetic laser medicine and surgery
• Development, production, service & training center in Jena
• TOP100 of the most innovative medium-sized businesses in Germany
QSPRO 100 1116 EN 2

The new generation of vascular lasers
DL5000 First argon laser for vascular treatments was introduced by

Asclepion in 1984. The new QuadroStarPRO will be the first Table-
DLS5
Top-Laser for aesthetic laser treatment, available in four different
wavelengths (yellow (577 nm), green (532 nm), 940 or 980 nm).
Product Development Milestones of vascular laser systems
ProYellow+
YellowStar
BeautyStar
QuadroStar
QuadroStar+
QSPRO 100 1116 EN 3

Specifications
Wavelength: 577 or 532 or 940 or 980nm

Application: Dermatology Dermatology minor surgery and nail treatment
Laser: HOPSL* (577, 532), class 4

Diode (940, 980), class 4
Power: Max. 5 Watt @ 577nm
Max. 8 Watt @ 532nm
Max. 30 Watt @ 940 or 980nm
Frequency: 0.5 to 100 Hz
Operating modes: BASIC, EXPERT, BURST, VARIX, CW, SCAN
Spot size: HOPSL: Standard 1.0 mm
HOPSL: optional 0.5; 1.5; 2.8 mm
Diode: for nail treatment 3.5 mm
(for minor surgery dependent on fiber)
Dimensions: 42 x 38 x 19 cm (B x T x H)
Weight: < 12 Kg
* HOPSL = High-power Optically Pumped Semiconductor Laser
QSPRO 100 1116 EN All specifications are subject to change without notice. 4
Features
Clinical success Features

• 1984: With the introduction of Argon laser • Table-Top-Laser in an elegant design
for treatment of vascular lesions of retina, • First laser available using yellow light
Asclepion took a leading role. With the • Available as yellow, green or infrared laser
KTP/LBO lasers BeautyStar, QuadroStar and • HOPSL-Technology with high reliability
QuadroStar+ Asclepion continues this • High power and speed
tradition. Over 500 systems, only in • Homogeneous beam profile
Germany show an exemplary success story. • Scanner and integrated cooling system
• More than 30 years experience • Foot switch to change Fluence & Speed
QSPRO 100 1116 EN 5

Scanner with skin cooling
Specifications
• Spot size: 1 mm,
Area maximum 15 x 15 mm
• Scan density: high
(100%; Spot by Spot; all shapes)
medium
(80%; distance 0.2mm; all shapes except point)
minimal
(60%; mild; distance 0.4mm; only big shapes)
• Shapes:
Scanner with skin cooling

Applications
• mild treatment of large areas
• easy switch of handpiece and scanner
• automatic detection of scanner by device
• skin cooling integrated in scanner and device
• available for QuadroStarPRO YELLOW
QSPRO 100 1116 EN 6
Accessories
• handpieces with different spot sizes

• fibers for several indications (e.g. EVLT)
• special footswitch to adjust the fluence and / or repetition rate for an efficient workflow
Standard handpiece Handpieces for fibers Foot switch
QSPRO 100 1116 EN 7

Design
Design – small, compact and light
• transportable Table-Top-System
• reduction in weight (>40%) and volume (>20%) along with the integration of the skin cooling*
• ergonomic tray for scanner and handpiece
QSPRO 100 1116 EN * Compared to the previous model QuadroStar+ 8

Technology
Technology – powerful, stable and efficient
• newest HOPSL-Technology (High-Power Optically Pumped Semiconductor Laser)
• newest skin cooling technology
• maximum power for vascular treatment
• high reliability
• foot switch to adjust the fluence & speed
• no running costs
QSPRO 100 1116 EN * Compared to the previous model QuadroStar+ 9

Display
Easy handling
• clear menu navigation
• clear and sharp display with touch sensitive keypad
• different background colors selectable
Mode Settings Application

BASIC Fluence, Frequency, (Ø Spot 1mm) Beginner
EXPERT Spot size, fluence, pulse duration, frequency Expert
BURST Spot size, fluence, pulse duration, frequency Difficult lesions
VARIX Power, pulse duration, interval Varicose vein
CW Power (total energy and pulse duration, incl. value set to zero) Surgery
SCAN Fluence, pulse duration, interval, spot density, shapes Scanner
TOOLS Pilot beam brightness, skin cooling, footswitch for setting Basics
QSPRO 100 1116 EN 10

Applications
QuadroStarPRO YELLOW QuadroStarPRO GREEN QuadroStarPRO 940 QuadroStarPRO 980

superficial vascular and benign pigmented lesions such as: endovenous treatment • nail treatment
• telangiectasia, couperosis, spider nevus (EVLT) • vaporization of soft
• cherry angioma, venous lake tissue
• small port wine stains, hemangioma, red leg veins
• sebaceous gland hyperplasia, warts, lentigines
QSPRO 100 1116 EN 11

Selective absorption
HIGH ABSORPTION
in hemoglobin: 100000
The blood heats up and
harms the inner vessel 10000
wall, this glued and
thus closes the vessel. 1000 Desoxy-Hemoglobin
Yellow light is having
the highest absorption.
Absorption Coefficient [cm-1]
100
Protein Water
LOW ABSORPTION Melanin

10
in water:
Minimizes risks of side
1
effects on light skin.
Oxy-Hemoglobin
HIGH ABSORPTION 0.1
in melanin:
Treatment of benign 0.01
pigmented lesions; NO
treatment on tanned 0.001 Scattering
skin or skin type V or
VI; Careful use on skin 0.0001
type IV! 100 200 300 400 500 1000 2000 3000 4000 5000 10000
Wavelength [nm]
QSPRO 100 1116 EN 12

QuadroStarPRO | vascular lesions
Penetration depth
PDL Argon KTP HOPSL Diode Nd:YAG
nm 510 514 532 577 800-980 1064
Port wine stains Telangiectasia

Hemangioma
Spider naevus
Venous lake
Fine reticular veins
Large reticular veins
QSPRO 100 1116 EN 13

Absorption
Advantages 577nm (YELLOW) vs. 532nm (GREEN)
• maximum of absorption in hemoglobin
Blood absorption coefficient (mm-1)

• absorption in blood 40% higher
• less absorption in melanin
• less side effects
• less fluence needed
• better results by equal fluence
Wavelength (nm)
 QuadroStarPROYELLOW is the best choice for vascular treatments
QSPRO 100 1116 EN Source: Welch, Van Gemert: Optical-Thermal Response of Laser-Irradiated Tissue, p. 815, ISBN 0-306-44926-9 14
Indications 532 nm 577 nm DYE*

Telangiectasia ++ +++ +++
Spider nevus ++ +++ +++
Rosacea ++ +++ +++
Wart ++ +++ +++
Sebaceous gland hyperplasia ++ +++ +++
Lentigines + + +
Small Hemangioma + ++ ++
Port wine stains + ++ +++
Small leg veins (superficial) + ++ ++
Side effects ++ +++ ++

Visibility ++ +++ +++
Reliability +++ +++ O
Follow-up costs +++ +++ O
System size +++ +++ O
Weight +++ +++ O
+ good, ++ very good, +++ optimal * Dye lasers from other manufactures
O poor
QSPRO 100 1116 EN 15
QuadroStarPRO YELLOW | Port wine stains (PWS)
scanner tests
after 5 days
532 nm 577 nm On the left, large scale
but superficial scabbing.
532 nm
31 J/cm2
11 ms
scanner at max. density
On the right, a significant vascular

reduction with a minimum of scabbing.
577 nm
19 J/cm2
11 ms
scanner at max. density
QSPRO 100 1116 EN By courtesy of Dr. P. Wood, Proderma, Bad Homburg, Germany 16
QuadroStarPRO YELLOW | Port wine stains (PWS)
scanner test
after 3 weeks
532 nm 577 nm right side: before treatment
left side: significant better removal
of PWS at the 577 nm
QuadroStarPRO YELLOW | Telangiectasia
before one month after

1 session
immediate reaction after

30 minutes
QSPRO 100 1116 EN By courtesy of LoraDerm Clinic, Zagreb, Croatia 18
before and after 1 month, 1mm spot size, 14-16 J/cm2, shortest pulse
QSPRO 100 1116 EN By courtesy of Dr. Arthur S. Simon, Jakarta, Indonesia 19

QuadroStarPRO YELLOW | Hemangioma
before
one month after
third session
one month after one month after

first session second session
before
Parameters:
Single scan circle 8mm, 15J/cm2, 32msec
15 days after
2 session
QSPRO 100 1116 EN By courtesy of Dr. Olga Bogomolets’ Institute of Dermatocosmetology, Oblast Mykolajiw, Ucraine 21
before
Parameters:
18 J/cm2, Scanner 8mm, 32msec, Single scan
15 days after
2 session
QSPRO 100 1116 EN By courtesy of Dr. Olga Bogomolets’ Institute of Dermatocosmetology, Oblast Mykolajiw, Ucraine 22
QuadroStarPRO YELLOW | Post acne erythema
before and after 1 month, Scanner 80% coverage, 70% cooling, 20 J/cm², shortest pulse

before and after 1 month, Scanner 80% coverage, 70% cooling, 20 J/cm², shortest pulse + brush 14 J/cm² on spots defocused 5 cm


QuadroStarPRO YELLOW | Pigmented & vascular lesions
before and after 1 month, 1 mm spot, 1 trace, 15 J/cm², shortest pulse

QuadroStarPRO YELLOW | Melasma
30 days after 2 sessions
before
30 days after 1 session

30 days after 2 sessions
before
Parameters:
14 J/cm2, scanner 100%
30 days after 1 session

QuadroStarPRO YELLOW | Lentigo
before and after 1 month, brush 12 J/cm² on spot defocused 5 cm, shortest pulse

QuadroStarPRO YELLOW | Keratosis
before and after 1 month, brush 12 J/cm² on spot defocused 5 cm, shortest pulse
before 30 days after 1 session

QuadroStarPRO YELLOW | Couperose/Rosacea
Spot 1mm, 12J/cm², 19ms
before 3 weeks after 1 treatment
immediate reaction:
QuadroStarPRO YELLOW | Couperose/Rosacea
typical
immediate reaction
using the scanner:
lighten up of
the scanned area
Scanner 100%, 19 J/cm², 11 ms
before 5 days after 1 treatment 3 weeks later
immediate reaction:
QuadroStarPRO GREEN | Telangiectasia
QSPRO 100 1116 EN By courtesy of Dr. Abror Shermatov, Taschkent, Uzbekistan 36

QuadroStarPRO GREEN | Telangiectasia
before after
QSPRO 100 1116 EN By courtesy of Karolina Kykalova, Prag, Czech Republic 37

QuadroStarPRO GREEN | Naevus araneus
before after
QSPRO 100 1116 EN 38

QuadroStarPRO GREEN | vascular lesions
Hemangioma Wart
CAVE: Children low Fluence!
Venous lake
QSPRO 100 1116 EN By courtesy of Dr. Petrow, Bonn, Germany 39

Reddened hypertrophic scars
before after

Port wine stain (cheek)
before after
QSPRO 100 1116 EN By courtesy of Dr. Petrow, Bonn, Germany 41

QuadroStarPRO GREEN | more treatments
Superficial pigmented lesions

• Solar Lentigo
• Freckle
• Hyper pigmentation after inflammation
Wart (seborrhoeic, viral, condyloma)

Fibroma
Adenoma sebaceous
Milia

QuadroStarPRO940
EndoVenous Laser Treatment
QSPRO 100 1116 EN 43

QuadroStarPRO 940 | EVLT
Endovenous laser treatment (EVLT)
During the procedure, a catheter bearing a laser fiber is inserted into the great saphenous vein or small
saphenous vein through a small puncture. The catheter is then advanced under ultrasound guidance by
means of a guide wire, which was inserted before. Under sonographic control the end of the catheter
fixed with the laser fiber is positioned 1-2 cm in front of the opening in the Vena femoralis. Dilute local
anesthetic is injected around and along the vein (perivascular infiltration). The catheter is withdrawn from
the fiber in a way that the end of the fiber juts out of the catheter at least 10mm. The laser is activated
whilst the catheter fixed to the laser fiber is slowly withdrawn, resulting in obliteration of the saphenous
vein along its entire length.
Laser effect Laser effect in the vein
QSPRO 100 1116 EN 44

EndoSet
This EndoSet serves for

carrying out endovascular
laser therapy and the
treatment of varices.
The treatment will be done

with an EndoFiber NIRQ600
and the Insertion Set among
local anesthesia.
QSPRO 100 1116 EN 45

Focus on security: EndoFiber NIR Q600 (Fiber) with catheter Insertion Set
• Catheter and fiber size are

concerted
• Fiber and catheter can be
coupled with each other,
which guarantees a safe
extraction of fiber and
catheter
• Fiber is visible in ultrasound
through a metal ring at the
end of the catheter, through
that the treatment becomes
more safe
• location of the end of the
fiber in the vessel is visible
through the skin, thanks to
pilot beam (additional
control through ultrasound
is necessary)
QSPRO 100 1116 EN 46



QuadroStarPRO980
Nail treatment for Onychomycosis
QSPRO 100 1116 EN 49

QuadroStarPRO 980 | Nail treatment
Onychomycosis: Fungal infections of the nails, especially of the toenails, are one of the
most common fungal diseases. About five percent of the population is asking for a
treatment, but the estimated number of people affected is approximately four to five times
higher. Most of patients consider the changes and discoloration of the nails as unattractive
and maybe a little embarrassing, but they do not pay this too much heed. But the
Onychomycosis is not a minor cosmetic problem only. If remains untreated, the infection
can spread up and destroys at the end the nail cells completely, which leads to separation of
the nail plate from nail bed.
QSPRO 100 1116 EN Source: Deutsche Haut - und Allergiehilfe e.V./ Picture by courtesy of Dr. Koch, Harsefeld, Germany 50
Laser treatment:
• Now there are several lasers with different parameters and treatment methods available and
used successfully, represent an additional option to the existing protracted therapies with high
relapse rates.
• All together is the wavelength in the near infrared (870-1320nm, which ensures good
penetration) and the goal is to heat the nail.
• The study situation is currently not clear what the mechanism of action relates (reached nail
temperature is not enough to destroy fungus or spores), but the application studies and
especially the practical experience in the treatment of many patients and their satisfaction
demonstrate the usefulness of the treatment.
• Nevertheless, it should be noted in the informed consent discussion that the treatment
improves the visual appearance of the nail and recurrences are possible (including the famous
The PinPointeTM FootLaserTM is approved by the FDA only for it: "is Indicated for use for the
temporary increase enlarge of clear nail in patients with Onychomycosis").
QSPRO 100 1116 EN 51

Laser treatment with the QuadroStarPRO980:
During laser treatment, the handpiece is moved quickly in serpentine pattern

from left to right, from top to bottom etc.
at the nail (including about 2mm skin surrounding the nail)
until a remarkable warming can be felt – but no pain
(otherwise stop treatment).
It is the goal to keep an tolerable temperature as long as possible.

To reach this, it is often the right way to apply low parameters –
than the treatment time can be longer in most cases.
The necessary treatment time depends on the size of the nail
(at big toe about 1.5 – 2min.) and on how much the nail is
discolored and thickened (less laser light penetrates the nail,
especially thick nails should be reduced in respect to the thickness before).
QSPRO 100 1116 EN 52

Big toe on the right (shooting with infrared camera)
Treatment time until 43°C is reached = 1min 20sec (small nail), no pain
continuously scanned nail including nail edge of approx. 2mm
before after 1 Min. 20 sec
QSPRO 100 1116 EN 53

before 4 month after one treatment
QSPRO 100 1116 EN Source: Asclepion Laser Technologies, Jena 54

QuadroStarPRO980
Laser assisted lipolysis (LAL)
QSPRO 100 1116 EN 55

QuadroStarPRO 980 | Laser assisted lipolysis
Indications
Reduction of local fat deposits, body contouring, slimming, skin tightening, collagen remodeling
Treatment areas
• abdomen, hips
• areas where liposuction is not appropriate or with poor response (neck, chin, knee-cap, under bra – line etc.)
• areas with previous liposuction and persisting skin laxity
Laser Lipolysis / Laser assisted Liposuction (LAL)

• The delivery of laser energy to subcutaneous tissue by an optic fiber before/after liposuction or without
liposuction (at small areas).
• Lipolysis procedure involves an optical fiber, which sticks out from the tip of a microcannula, which is inserted
through a tiny skin incision into subcutaneous fat.
• The optical fiber is moved throughout the fat in a pattern resembling the spokes of a fan.
Tumescence anesthesia
• diluted local anesthesia is injected into the fat layer
• no general anesthetic necessary – significant less risk
Mechanism
The laser melts unwanted fat efficiently by selectively targeting adipose fat and damages the
dermal collagen by heat and causes shrinkage and ultimately neocollagenesis prompting
reduction of lines and wrinkles and providing skin tightening.
QSPRO 100 1116 EN 56

Advantages laser technology Advantages QuadroStarPRO980
• smoother skin with less deformities compared to • Table top system with high power for shorter
liposuction treatment times
• faster healing with smaller incisions, less bruising, reduced • different canulas and fibers available
pain minimal blood loss and swelling (200, 300, 400 and 600 µm)
• cw – technology allows superior controlling of thermal • special LipoSet with sterile fibers
effect vs. competing high peak power pulsed laser; (300 and 600 µm) and handpieces
competing systems using short (200 µs) peak power
• no consumables
pulses cause extreme temperatures in the tissue, leading
to disruptive photomechanical and photo acoustic effects;
these temperatures are high enough to cause unnecessary
boiling and vaporization at the end of their tip
QSPRO 100 1116 EN 57

Facilities and tools

• operations theatre (sterile area)
• Asclepion lipolysis bare fiber set L (300 µm and 600 µm fibers, handpieces, cannulas
Scalpel No. 11, 4x4 gauze, 20 cc syringe, 5 cc syringe
20 G spinal needle, 25 G needle, kidney pot, skin marker, bandage, drainage set, suction system
Surgery procedures
• Preparation of QuadroStar+ with accessories
• Preparation tumescent solution, Lipolysis Set
• Lipolysis surgery
Pre-OP preparation
• Equipment preparation and sterilization
• Body examination
• Pre-OP medication
• Surgery line
• Picture records
• Body disinfection
• Anesthesia (tumescent therapy)
Post-OP care
• Picture records
• Massage
QSPRO 100 1116 EN 58

Preparation of LipoSet
• insert fiber into handpiece
• fiber has to jut out of cannula 5 - 7 mm in order to prevent
heating of cannula and thus skin burns, fiber must be fixed !!
Surgery preparation
• QuadroStar 980: check function and select correct cw – mode
• connection of fibers
• safety goggles
• red aiming beam must be visible (brightness adjustment)
Parameter setting
• tight tissue: cw, 6 - 10 Watt, 300 µm fiber
• floppy tissue: cw, 4 - 8 Watt, 300 µm fiber
Experienced user may run high effective and high speed procedures
by using 600 µm fiber, cw, 15 – 18 Watt.
QSPRO 100 1116 EN 59

LipoSet
• 2 handpieces (300 µm and 600 µm)
• 1 fiber 300 µm/3m and 1 fiber 600 µm/3m
• 1 x 15 cm and 1 x 8 cm cannula for 600 µm, 1 x 5 cm and 1 x 10 cm
and 1 x 15 cm cannula for 300 µm
Following information are examples – the necessary medication including

quantity has to be decided by the physician !!
Medications
Midazolam (Dormicum ™, Benzodiazephrine) (oral)
Tumescent solution (injection)
• 0,9% normal saline 1000 ml
• 2% lidocaine 50 ml
• Adrenaline 1: 100.000 1 ml
• 8,4 % sodium bicarbonate 12,5 ml
• 10 mg triamcinolone acetonide 1 ml
• total concentration 50/1064.5 = 0,093 % lidocaine
• tumescent injection volume is 150 – 250 ml cc per 10 x 10 cm area

• at incision points more volume is required
• less volume is required if liposuction is not performed
• volume decision to be taken by physician
QSPRO 100 1116 EN 60

Prepare tumescent as an anesthetic
Use tumescent cannula or spinal

needle with 20 ml syringe or pump to
inject solution into fat layer
Spread tumescent evenly in a fan

shape, use fan method according
diagram below
QSPRO 100 1116 EN 61

Body examination and marking

• pinch test: examine location and thickness of fat layer
• incisions, operation area, anesthesia area, intensive area
QSPRO 100 1116 EN 62

Incision
Fan method
Surgery line
Tumescent line
• quick forward and

backward move cannula
creates channels
and septum in fat tissue
• speed is around 10 cm
per second
QSPRO 100 1116 EN 63

Clinical results
Lipolysis using a 980-nm Diode Laser: A Retrospective Analysis of 534 Procedures
Jean Pascal Reynaud1, Martine Skibinski1, Benjamin Wassmer2, Philippe Rochon2, 3 and Serge Mordon3
Total Total Tumescent Tumescent

No. procedures No. patients
Location energy (J) energy (J) infiltration (ml) infiltration (ml)
(534) (334)
Mean SD Mean SD
Hips 197 103 14,551 7,082 329 113
Abdomen 86 86 24,585 12,623 573 188
Thighs 61 32 10,427 5,581 264 82
Knees 61 34 8,140 4,401 112 56
Flanks 57 30 9,533 5,898 231 75
Buttocks 28 14 13,140 8,821 311 193
Chin 22 22 11,742 3,573 215 82
Arms 18 9 12,812 5,614 229 93
Back 4 4 21,913 12,374 675 106
QSPRO 100 1116 EN 64

Applied energy per area
QSPRO 100 1116 EN 65

Time table respective power applied
QuadroStar power available: 30 Watt in tissue
2500 Joule 3000 Joule 3500 Joule
6 Watt 7 Min. 8 Min. 10 Min.
9 Watt 4.5 Min. 5.5 Min. 6.5 Min.
QSPRO 100 1116 EN 66

Patient satisfaction
Lipolysis using a 980-nm Diode Laser: A Retrospective Analysis of 534 Procedures
Jean Pascal Reynaud1, Martine Skibinski1, Benjamin Wassmer2, Philippe Rochon2, 3 and Serge Mordon3
QSPRO 100 1116 EN 67



Treatment results
before treatment
before treatment 1 day after one treatment 5 days after one treatment
QSPRO 100 1116 EN By courtesy of Yann Renoulet, Dorsten, Germany 70

Treatment results
before treatment 1 month after one treatment
QSPRO 100 1116 EN By courtesy of Yann Renoulet, Dorsten, Germany 71

Bibliography | QuadroStarPRO
VASCULAR LESIONS (532 & 577 nm)
Treatment of superficial vascular lesions with the KTP 532-nm laser: experience with 647 patients.
Becher GL, Cameron H, Moseley H. Lasers Med Sci. 2014 Jan;29(1):267-71. doi: 10.1007/s10103-013-1330-5. Epub 2013 Apr 30.
Treatment of superficial cutaneous vascular lesions: experience with the KTP 532 nm laser
Clark C, Cameron H, Moseley H, Ferguson J, Ibbotson SH. Photobiology Unit, Department of Dermatology, Ninewells Hospital Medical School,
University of Dundee, DD1 9SY, UK. Lasers Med Sci. 2004;19(1):1-5.
Comparison of the 532-nm KTP and 1064-nm Nd:YAG lasers for the treatment of cherry angiomas
Pancar GS1, Aydin F, Senturk N, Bek Y, Canturk MT, Turanli AY. Department of Dermatology, Ondokuz Mayis University School of Medicine,
Samsun, Turkey. J Cosmet Laser Ther. 2011 Aug;13(4):138-41. doi: 10.3109/14764172.2011.594058. Epub 2011
Acne rosacea: effectiveness of 532 nm laser on the cosmetic appearance of the skin
Maxwell EL1, Ellis DA, Manis H. Art of Facial Surgery, Facial Plastic Reconstructive Surgery, Toronto, ON lindamaxwell22@hotmail.com.
J Otolaryngol Head Neck Surg. 2010 Jun;39(3):292-6.
Treatment of spider leg veins with the KTP (532 nm) laser--a prospective study.
Spendel S, Prandl EC, Schintler MV, Siegl A, Wittgruber G, Hellbom B, Rappl T, Berghold A, Scharnagl E. Lasers Surg Med. 2002;31(3):194-201.
The utilization of a new yellow light laser (578 nm) for the treatment of class I red telangiectasia of the lower extremities.
Sadick NS, Weiss R. Dermatol Surg. 2002 Jan;28(1):21-5.
Copper bromide laser treatment of facial telangiectasia: results of patients treated over five years.
McCoy SE. Lasers Surg Med. 1997;21(4):329-40.
An evaluation of the copper-bromide laser for treating telangiectasia.

McCoy S., Hanna M, Anderson P, McLennan G, Repacholi M. Dermatol Surg. 1996 Jun;22(6):551-7.
QSPRO 100 1116 EN 72

PIGMENTED LESIONS (532 & 577 nm)
Clinicopathologic efficacy of copper bromide plus/yellow laser (578 nm with 511 nm) for treatment of melasma in Asian patients.
Lee HI, Lim YY, Kim BJ, Kim MN, Min HJ, Hwang JH, Song KY. Dermatol Surg. 2010 Jun;36(6):885-93. doi: 10.1111/j.1524-4725.2010.01564.x.
Epub 2010 May 7.
Split treatment of photodamaged skin with KTP 532 nm laser with 10 mm handpiece versus IPL: a cheek-to-cheek comparison.
Butler EG 2nd1, McClellan SD, Ross EV. Lasers Surg Med. 2006 Feb;38(2):124-8.
OTHER LESIONS (532 & 577 nm)

Two-year follow-up results of copper bromide laser treatment of striae.
Longo L, Postiglione MG, Marangoni O, Melato M. J Clin Laser Med Surg. 2003 Jun;21(3):157-60.
Recalcitrant viral warts: results of treatment with the KTP laser.

Gooptu C, James MP. Clin Exp Dermatol. 1999 Mar;24(2):60-3.
ENDOVASCULAR LASERTHERAPY (940 nm)

Endovenous laser treatment of saphenous veins: is there clinical difference using different endovenous laser wavelenghts?
Cavallini A. Int Angiol. 2015 Feb;34(1):1-8. Epub 2014 Jun 13.
Endovenous laser treatment (EVLT) for the saphenous reflux and varicose veins: a follow-up study.
Firouznia K, Ghanaati H, Hedayati M, Shakiba M, Jalali AH, Mirsharifi R, Dargahi A. J Med Imaging Radiat Oncol.
2013 Feb;57(1):15-20. doi: 10.1111/j.1754-9485.2012.02457.x. Epub 2012 Oct 9.
QSPRO 100 1116 EN 73

NAIL TREATMENT (980 nm)
Laser therapy of onychomycosis.
Nenoff P1, Grunewald S, Paasch U. J Dtsch Dermatol Ges. 2014 Jan;12(1):33-8. doi: 10.1111/ddg.12251. Epub 2013 Nov 18.
Antifungal efficacy of lasers against dermatophytes and yeasts in vitro.

Paasch U, Mock A, Grunewald S, Bodendorf MO, Kendler M, Seitz AT, Simon JC, Nenoff P. Int J Hyperthermia. 2013 Sep;29(6):544-50.
Heat profiles of laser-irradiated nails.

Paasch U, Nenoff P, Seitz AT, Wagner JA, Kendler M, Simon JC, Grunewald S. J Biomed Op. 2014 Jan;19(1):18001.
VAPORIZATION OF SOFT TISSUE (980 nm)

Evaluation of safety and efficacy of 980-nm diode laser-assisted lipolysis versus traditional liposuction for submental rejuvenation:
A randomized clinical trial.
Valizadeh N, Jalaly NY, Zarghampour M, Barikbin B, Haghighatkhah HR. J Cosmet Laser Ther. 2015 Jul 3:1-6. [Epub ahead of print]
Laser assisted lipolysis for neck and submental remodeling in Rohrich type I to III aging neck: a prospective study in 30 patients.
Leclère FM, Moreno-Moraga J, Alcolea JM, Casoli V, Mordon SR, Vogt PM, Trelles MA. J Cosmet Laser Ther. 2014 Dec;16(6):284-9.
doi: 10.3109/14764172.2014.946053. Epub 2014 Sep 19.
Results of Laser assisted Lipolysis using a 980 nm diode Laser

Yann Renoulet, MD. 2010. Plastic and Reconstructive Surgery Center, Center for Lasertherapy,
Elisabeth Krankenhaus Recklinghausen,Recklinghausen, Germany
Safety of Laser assisted Lipolysis using a 980 nm diode Laser

Yann Renoulet, MD. 2010. Plastic and Reconstructive Surgery Center, Center for Lasertherapy,
Elisabeth Krankenhaus Recklinghausen, Recklinghausen, Germany
QSPRO 100 1116 EN 74
www.asclepion.com

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Available Formats

QuadroStarPRO Family

- 577, 532, 940 & 980 nm Laser -

• Development, production, service & training center in Jena

• TOP100 of the most innovative medium-sized businesses in Germany

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DL5000 First argon laser for vascular treatments was introduced by

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Wavelength: 577 or 532 or 940 or 980nm

Laser: HOPSL* (577, 532), class 4

* HOPSL = High-power Optically Pumped Semiconductor Laser

Clinical success Features

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Scanner with skin cooling

• handpieces with different spot sizes

Standard handpiece Handpieces for fibers Foot switch

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QSPRO 100 1116 EN * Compared to the previous model QuadroStar+ 8

QSPRO 100 1116 EN * Compared to the previous model QuadroStar+ 9

Mode Settings Application

EXPERT Spot size, fluence, pulse duration, frequency Expert

BURST Spot size, fluence, pulse duration, frequency Difficult lesions

VARIX Power, pulse duration, interval Varicose vein

SCAN Fluence, pulse duration, interval, spot density, shapes Scanner

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QuadroStarPRO YELLOW QuadroStarPRO GREEN QuadroStarPRO 940 QuadroStarPRO 980

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LOW ABSORPTION Melanin

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Port wine stains Telangiectasia

Fine reticular veins

Large reticular veins

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• maximum of absorption in hemoglobin

Blood absorption coefficient (mm-1)

 QuadroStarPROYELLOW is the best choice for vascular treatments

Indications 532 nm 577 nm DYE*

Side effects ++ +++ ++

On the right, a significant vascular

before one month after

immediate reaction after

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one month after one month after

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before and after 1 month, 1 mm spot, 1 trace, 15 J/cm², shortest pulse

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30 days after 2 sessions

30 days after 1 session

30 days after 2 sessions

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QSPRO 100 1116 EN By courtesy of Dr. Arthur S. Simon, Jakarta, Indonesia 30

before 30 days after 1 session

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Spot 1mm, 12J/cm², 19ms

before 3 weeks after 1 treatment

Scanner 100%, 19 J/cm², 11 ms

before 5 days after 1 treatment 3 weeks later

QSPRO 100 1116 EN By courtesy of Dr. Abror Shermatov, Taschkent, Uzbekistan 36