1. Low back pain is a common symptom that can be caused by mechanical issues like herniated discs or osteoarthritis, or non-mechanical pathologies like tumors or infections.
2. Red flags indicating a more serious condition include failure to improve with conservative treatment, neurological deficits, or risk factors for conditions like cancer. Imaging is recommended for red flag cases or when a specific diagnosis is suspected.
3. Lumbar radiculopathy is a common mechanical cause of low back pain, often caused by disc herniation or stenosis impinging a nerve root, resulting in pain that radiates down the leg.
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Conditions of The Lumbar Spine
1. Low back pain is a common symptom that can be caused by mechanical issues like herniated discs or osteoarthritis, or non-mechanical pathologies like tumors or infections.
2. Red flags indicating a more serious condition include failure to improve with conservative treatment, neurological deficits, or risk factors for conditions like cancer. Imaging is recommended for red flag cases or when a specific diagnosis is suspected.
3. Lumbar radiculopathy is a common mechanical cause of low back pain, often caused by disc herniation or stenosis impinging a nerve root, resulting in pain that radiates down the leg.
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LUMBAR SPINE
o Metastatic CA – hx of CA, unexplained weight loss,
rest pain, age >50 o Infection – unexplained fever, recent bacterial Conditions of the Lumbar Spine infection, immunosuppression, IVDA Low Back Pain o Fx – steroids, osteoporosis, recent trauma, age >70 Is a symptom, not a disease o Cauda Equina Syndrome – urinary 80% lifetime prevalence, m/c cause of disability in pts < 45 retention/incontinence, saddle anesthesia, ↓ rectal y/o (one of the causes of absenteeism) tone, (B) LE weakness/numbness Pain, muscle tension, or stiffness localized below the costal o Severe/progressive focal neurologic deficit margin and above the inf gluteal folds, c or s leg pain o Failure to improve c therapy International Association for the Study of Pain (IASP) o Pain > 4 wks o Low Back Pain Red Flags incidence: Lumbar spinal pain o Compression Fx (4%) Sacral spinal pain Osteoporosis Lumbosacral pain Location: thoracolumbar junction, midthoracic o Gluteal and Loin Pain (not considered as LBP) spine Classification (Etiology): Thoracolumbar fx may present c lumbosacral o Mechanical – biomechanics of the lumbar area, pain problems c the structures; HNP, OA, spinal stenosis, o Metastatic CA (0.7%) spondylolisthesis, compression fx Past hx of CA is single strongest indicator Non-radicular Metastatic (prostate, lung, breast) Radicular – involves nerve root impingement Multiple myeloma o Non-mechanical – pathologic Tumor – metastases, MM, lymphoma Lymphoma Infection – osteomyelitis, diskitis ↑ post-test probability from 0.7% - 9% Inflammatory Arthritis – RA, AS Not including non-melanoma skin CA o Visceral diseases – Aortic Abdominal Aneurysm, o Cauda Equina Syndrome (0.04%) nephrolithiasis, pancreatitis, prostatitis Large central disc herniation (L4-L5) Urinary retention initially overflow Classification (Diagnosis): incontinence o Complicated – red flag conditions Normal post-void residual of urine essentially o Specific Diagnosis rules it out Lumbar radiculopathy Surgical emergency Lumbar spinal stenosis o Infection (0.01%) Other conditions such as AS Non-spinal LBP o Uncomplicated (non-specific) – used to be called o AAA mechanical LBP, dx of exclusion, > 85% of LBP in o Nephrolithiasis primary care Acute: < 1 mo, rapid improvement in first o Pancreatitis month in most pts, recurrence rate up to 1/3, 7- o Prostatitis 10% progress to chronic back pain o Pelvic Inflammatory Disease Subacute: 1-3 mos Possible anatomic sources of LBP – controversial Chronic: > 3 mos o Discs (back pain), facet jts (back, buttock, thigh pain), Red flags: SI jts, ligaments, muscles (back pain) Innervated structures: Pts are highly responsive to tricyclic o Bone: vertebrae antidepressants o Jts: Zygoapophyseal More predictive of outcome than severity of o Disk: External annulus fibrosus, potentially diseased pain or exam findings disk o Durations of Symptoms o Ligaments: ALL, PLL, interspinous Status of pts @ 2 mos may help predict o Muscles and fascia outcome @ 12 mos o Nerve roots Summary Non-innervated structures: Ligamentum flavum, internal o Be aware of red flags annulus fibrosus, nucleus pulposus o Identify specific dx Yellow flags: o Uncomplicated LBP is a dx of exclusion o Previous hx of disability o MRI for complicated and specific dx o Inconsistent findings o Diagnostic injections o Abnormal pain behavior o Don’t forget the yellow flags o Litigation Lumbar Radiculopathy o Work dissatisfaction o L4-L5 or L5-S1 (90%), L5 and S1 nerve roots o Attention-seeking o Inflammation > mechanical compression o Preference for prolonged bed rest o Phosopholipase A2, TNF-alpha o Depression o Pain c sitting, bending, coughing, radiates below the o Chemical dependency knee in a narrow band o Hx of abuse Nerve Pain Motor Sensory DTR Root Referral o Family hx of chronic pain L4 Medial leg Ankle Medial Knee Waddell’s Signs – behavioral response to exam, not a proof of dorsiflexi ankle malingering, > 3 signs suggests presence of non-organic on factors L5 Lateral leg, Great toe Web space No o Superficial tenderness – pain elicited from light dorsal foot dorsiflexi between 1st reliable touch on skin on and 2nd toe reflex o Simulation – back pain produced by activities that S1 Post calf, Foot Lateral Ankle should not be painful e.g. axial loading of the head (1- lateral or plantar aspect of 2 lbs), passive rotation of shoulders and pelvis in same sole of foot flexion the sole of plane foot o Distraction – Symptomatic response to a test changes when test is repeated while pt is distracted, Radicular vs. Referred Pain adjunct for Cognitive Behavioral Therapy Radicular Pain Somatic-referred Pain o Regionalization – ratchet-like “giving way” weakness Leg > Back Back > Leg Shooting, lancinating, Dull, pressure-like, deep or non-neuroanatomic numbness cutaneous component o Overreaction – disproportionate response to routine Travels along limb in a Extends into limbs across a exams such as collapsing, grimacing, guarding, narrow band wide region groans, tremors, etc (+)/(-) neurologic defect (-) neurologic deficit Prognosis Listing away from side of disc herniation (paracentral o Psychosocial risk factors herniation) Yellow flags and Waddell’s Signs SLR for L5 or S1 root o Reproduction of radicular pain bet 30-70° Dx: posterolateral, oblique view demonstrate collar on Scotty o High sensitivity but low specificity Dog, bone scans (+) 5-7 days and last up to 18 mos o Crossed SLR (Well Leg Raising) is more specific but Spondylolisthesis less sensitive Forward or backward slippage of one vertebral body to Natural Hx another, commonly seen in the lumbar region o Favorable Six categories: o Conservative and surgical tx are both successful o Isthmic - m/c, stress fx of pars interarticularis o Large extruded discs are more likely to ↓ in size o Dysplastic – Congenital, dysplasia of facet joints Spinal Stenosis o Degenerative – older spine, long-standing instability Degenerative changes resulting in disc space narrowing, from generation, commonly affects L4-L5 level vertebral body osteophytosis, jt arthropathy, which narrows o Traumatic – rare, acute fx secondary to trauma the central canal and lateral recesses (neuroforamina) o Pathologic – medical causes that can cause ↓ bone Possible neural compression and ischemia strength Usually present at ~50 y/o affecting the L3 and L4 at the o Postsurgical – instability from extensive lumbar region decompression Differential dx of intermittent claudication Occurrence 2-4x more likely in males o Intermittent Claudication – relieved by rest Meyerding Grading of Slippage o Neurogenic intermittent claudication (Pseudo) – Grade 0 0% slippage relieved by FLEX, use Bicycle Test of van Gelderen Grade 1 1-25% slippage Etiology o Congenital Grade 2 26-50% Hereditary slippage Achondroplastic/dwarfism Grade 3 51-75% o Acquired slippage Degenerative (m/c) Grade 4 76-100% Spondylotic/spondylolisthetic slippage Iatrogenic (postsurgical) Spondyloptosis >100% Posttraumatic slippage Metabolic (Paget’s disease) o Traumatic Lumbar Spinal Stenosis o Combined Congenital, onset in 30s Neurogenic claudication – pain in buttocks, thigh, and leg c Acquired standing, relieved by sitting and bending forward o Degenerative Spondylolysis M/c, late 50s – early 60s, commonly involved M/c seen in children and adolescents at the L5 vertebral level L4-L5, followed by L3-L4 and occurs at the pars interarticularis (pedicle, transverse Commonly affects 2-3 spinal segments process, lamina, and articulator processes) o Mechanical Compression Commonly unilateral Compression of microvasculature nerve root Localized back pain exacerbated by motion (HYPEREXT), ischemia, ↑ microvascular permeability and standing, lying prone, relieved by FLEX, normal neurologic edema exam Insidious, chronic LBP that progresses to buttock, thigh, and to restrictive lung disease), plain films typically normal in leg pain, fatigue, heaviness, pain in the legs c ambulation early stages (neurogenic claudication) Herniated Nucleus Pulposus Intermittent claudication – commonly seen in pts c ASO A disc injury in which the nucleus pulposus migrates through (arteriosclerosis obliterans) highest risk factor is smoking, the annulus fibrosus, most commonly occurs at ages 30-40 TAO (thromboangiitis obliterans, Buerger’s disease) and a higher prevalence in the lumbar (L4-L5 or L5-S1) and cervical (C5-C6) regions Symptoms Neurogenic Vascular M/c direction: posterolateral, which compresses the point of Back Pain Common Uncommon exit of spinal nerve roots, is one of the causes of Sitting/flexed position Not positional radiculopathy Standing and resting Pain relief when Classification: Pain Relief usually insufficient standing o Bulging – No annulus defect, disc convexity is beyond Often slow (>5 mins) Almost immediate vertebral margin Ambulatory o Prolapsed – Nuclear material protrudes into an annulus Variable Fixed tolerance defect Uphill vs. Downhill more painful Uphill more painful o Extruded – Nuclear material extends into the PLL Downhill Bicycle ride No pain Pain o Sequestered disc – Nuclear fragment free in the canal Common exam findings: Dx: o Loss of lumbar lordosis c limited EXT, trunk FLEX o ↓ disc height, vertebral osteophytosis, sclerosis, forward in standing and walking (Simian posture), no radiography significant tenderness, (-) SLR, (n) motor exam despite o Disc desiccations, annular tears, HNP – MRI report of weakness Tx: o MRI o Medications (COX2 inhibitors, anti-neuropathic pain) Mild – 75-99 o McKenzie Program to centralize extremity pain – LB Moderate – 50-74 exercise (EXT) (Williams Program - FLEX) Severe - <50 o Lumbar corsets Natural hx: o Vertebral distraction may relieve compression o P 4 yrs: Cervical – 20-30° of FLEX c 25 lbs of resistance 70% no change Lumbar – may require ↑ force (at least ½ of 15% improved BW) /split table 15% worsened o 5-15% may have coexisting cervical spinal stenosis Ankylosing Spondylitis – rheumatologic, classified as a seronegative spondyloarthropathy (negative Rheumatoid Factor) Seronegative spondyloarthopathies: Psoriasis, AS, Reactive Arthritis, Inflammatory Bowel Disease Crooked vertebra, bamboo spine Earliest clinical features: o Gradual onset in males < 30 y/o, primary manifestation: morning stiffness, improves c exercise, not relieved by rest Schober’s Test, chest expansion < 2.5 cm (last stage) (costovertebral and costotransverse jts involvement) (prone
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