CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY, BHILAI

Course of study and scheme of Examination

Diploma in Pharmacy (Part-II) Examination

SECOND YEAR
Periods Per Scheme of Examination
Subject Board of Week Theory Practical Total
S. No Subject
Code Study EY Marks
L T P Sessional EYE Sessional
E
1 241211 Pharmacy Pharmaceutics-II 3 - - 80 20 - - 100
Pharmaceutical
2 241212 Pharmacy 4 - - 80 20 - - 100
Chemistry -II
Pharmacology and
3 241213 Pharmacy 3 - - 80 20 - - 100
Taxicology
Pharmaceutical
4 241214 Pharmacy 2 - - 80 20 - - 100
Jurisprudence
Drug Store and
5 241215 Pharmacy Business 3 - - 80 20 - - 100
Management
Hospital and
6 241216 Pharmacy 3 - - 80 20 - - 100
Clinical Pharmacy
Pharmaceutics-II -
7 241221 Pharmacy - - 4 - 80 20 100
Lab -
-
8 241222 Pharmacy Pharm. Chem-II Lab - - 3 - 80 20 100
-
Pharmacology and -
9 241223 Pharmacy
Taxicology Lab
- - 2 -
-
80 20 100
Hospital and
-
10 241224 Pharmacy Clinical Pharmacy - - 2 - 80 20 100
-
Lab
Total 18 11 480 120 320 80 1000

L – Lecturer, T – Tutorial, P – Practical,

EYE- End Year Exam

 CHHATTISGARH SWAMI VIVEKANAND TECHNICAL
UNIVERSITY, BHILAI

Year : 2nd Branch : Diploma in Pharmacy

Subject : Pharmaceutics II Code : 241211

Theory : 75 hrs.

Total Marks in End Semester Exam : ……………….

1. Dispensing Pharmacy
(i) Prescription- Reading and understanding of prescription : Latin terms
commonly used (detailed study is not necessary) Modern methods of
prescribing, Adoption of metric system, Calculation involved in
dispensing.
(ii) Incompatibilities in prescription : Study of various types of
incompatibilities-physical, chemical and therapeutic.
(iii) Posology : Does and dosage of drugs, factors influencing does,
calculation of does on the basis if age, sex and surface area, veterinary
does.
2. Dispensed Medication :
(Note : A detailed study of the following dispensed medication is necessary.
Methods of preparation with theoretical and practical aspects, use of appropriate
contains and closures, special labeling requirements and storage conditions should be
high-lighted)

(i) Powders – Type of powders, advantage and disadvantage of powders,

granules, cachets and tablet triturates, preparation of different types of
powders encountered in prescription, weighing methods, possible
errors in weighing, minimum weighable amounts and weighing of
material below the minimum weighable amount, geometric dilution
and proper usage and care of dispensing balance.
(ii) Liquid Oral Dosage Forms :
(a) Monophasic-theoretical aspects including commonly used
vehicle, essential adjuvant like stabilizers, colorants and flavors
with examples.
Review of the following monophasic liquid with details of
formulation and practical methods.
Liquids for internal administration Liquids for external administration or used
on mucus membranes
Mixtures and concentrates syrups Gargles
Mouth washes
Elixirs Throat-paints
Douches
Ear Drops
Nasal drops & sprays
Liniments
Lotions
 (b) Biphasic Liquid Dosage Forms :
(i) Suspensions (elementary study)- Suspensions containing diffusible
solids and liquids and their preparations. Study of the adjuvant used like
thickening agents, wetting agents, their necessity and quantity to be
incorporated. Suspensions of precipitate forming liquids like tinctures, their
preparations and stability. Suspensions produced by chemical reaction. An
introduction to flocculated, non flocculated suspension system.

(ii) Emulsions- Types of emulsions, identification of emulsion system,

formulation of emulsions, selection of emulsifying agents, instabilities in
emulsion, preservation of emulsions.

(III) Semi-Solid Dosage Forms :

(a) Ointments – Types of ointments. Classification and selection of dermatological

vehicles. Preparation and stability of ointments by the following processes:
(i) Trituration (ii) Fusion (iii) Chemical reaction (iv) Emulsification.

(b) Pastes – Deference between ointments and pastes. Bases of pastes preparation of
pastes and their preservation.
(c) Jellies – An introduction to the different types of jellies and their preparation.
(d) An elementary study of poultice.
(e) Suppositories and pessaries – Their relative merits and demerits. Types of
suppositorics. Suppository bases, classification, properties. Preparation and
packing of suppositorics. Use of suppositorics for drug absorption.

(iv) Dental and Cosmetic preparation:

Introduction to Dentrifices . Facial cosmetics. Deodorants, Antiperspirants,
Shampoos, Hair dressings and Hair removers

(v) Sterile Dosage Forms:

(a) Parenteral dosage forms – Definitions, General requirement for parenteral
dosage forms. Types of parenteral formulations, vehicles, adjuvants,
processing, personnel, facilities and Quality control. Preparation of
intravenous fluids and admixtures – total parenteral nutrition, Dialysis
fluids.
(b) Sterility testing. Particulate matter monitoring – faulty seal packing.
(c) Ophthalmic products – Study of essential characteristics of different
ophthalmic preparations. Formulation additives, special precautions in
handling and storage of ophthalmic products.

PRACTICAL (100 Hours) CODE – 241221

Dispensing of at least 100 products covering a wide range of preparations such as

mixtures, emulsions, lotions, liniments, E.N.T. preparations, ointments, suppositories,
powders, incompatible prescriptions etc. Books recommended: (Latest editions )
1. Indian – Pharmacopoeia.
2. British Pharmacopoeia .
3. National Formularies (N.F.I. B.N.F.)
4. Remington’s Pharmaceutical Sciences.
5. Martindale Extra Pharmacopoeia.
 CHHATTISGARH SWAMI VIVEKANAND TECHNICAL
UNIVERSITY, BHILAI

Year : 2nd Branch : Diploma in Pharmacy

Subject : Pharmaceutical Chemistry II Code : 241212

Theory : 100 hrs.

Total Marks in End Semester Exam :………

Minimum number of class tests to be conducted : 02

1. Introduction to the nomenclature of organic chemical systems with particular

reference to heterocyclic system containing up to 3 rings.
2. The Chemistry of following Pharmaceutical organic compounds, covering their
nomenclature, chemical structure uses and the important Physical and Chemical
properties (Chemical structure of only those compounds marked with asterisk)

The stability and storage conditions and the different type of Pharmaceutical formulations
of these drugs and their popular brand names.

Antiseptics and Disinfectants – Proflavine, Benzal koniumchloride, Cetrimide,

Chloroeresol*, Chloroxylene, Formaldehyde solution, Hexachlorophene.Liquified
phenol, Nitrofurantoin.

Sulfonamides – Sulfadiazine, Sulfaguanidine*, Phthalylsulfathiazole,

Sueeinylsulfathiazole, Sulfadimethoxine, Sulfamethoxypyridazine. Sulfamethoxazol. Co-
trimoxazole, Sulfacetamide*.

Antileprotic Drugs – Clofazimine. Thiambutosine. Dapsone* Solapsone.

Anti-tubereular Drugs – Isoniazid* PAS Streptomyein Rifampiein, Ethambutol,

Thiacetazone, Ethionamide, Cyeloserine, Pyrazinamide*,

Antiamoebic and Anthelmintic Drugs – Emetine, Metronidazole*, Halogenated

hydroxyquiolines, diloxanidefuroate, paramomyein Piperazine, Mebendazole, D.E.C*.

Antibioties – Benzyl Penicillin* Phenoxy methyl Penicillin*, Benzathine, Penicillin,

Ampicillin, Cloxacillin, Carbenicillin, Gentamicin, Neomycin, Erythromycin,
Tetracycline, Cephalexin, Cephaloridine, Cephalothin, Griseofulvin, Chloramphenicol.

Antifungal agents – Undeeylenic acid, Tolnaftate, Nystatin, Amphotericin, Hamycin.

Antimalarial Drugs – Chloroquine*, Amodiaquine, Primaquine, Proguanil,

Pyrimethamine*, Quinine. Trimethoprim.

Tranquilizers – Chlorpromazine*, Prochlorperazine, Trifluoperazine, Thiothixene,

Haloperidol*,
Hypnotics:- Phenobarbitone, Butobarbitone, Cyelobarbitone, Nitrazepam, Glutethimide,
Methyprylone, Paraldehyde, Triclofos sodium.

General Anesthetics – Halothane, Cyclopropane*, Diethyl ether*, Methohexital sodium,

Thiopental sodium, Trichloroethylene.

Antidepressant Drug – Amitriptyline, Nortryptyline, Imipramine*, Phenelzine,

Tranylcypromine.

Analeptics – Theophylline, Caffeine*, Coramine* Dcxtroamohetamine,

Adrenergic Drugs – Adrenaline* Noradrenaline, Isoprenaline*, Phenylephrinc

Salbutamol, Terbutaline, Ephedrine*, Pseudoephedrine.

Adrenergic Antagonist – Tolazoline, Propranolol*, Practolol.

Cholinergic Drugs – Neostigmine*, Pyridostigmine,Pralidoxime, Pilocaroine,

Physostigmine*

Cholinergic Antagonists – Atropine*, Hyscinc, Homatropine, Propantheline*,

Benztropine, Tropicamide, Biperiden*.

Diuretic Drugs – Furosemide*, Chlorothiazide, Hydrochlorothiazide*, Benzthiazide,

Urea*, Mannitol, Ethacrynic Acid.

Cardiovascular Drugs – Ethyl nitrite*, Glyceryl trinitrate, Alpha methyl dopa,

Gauanethidine, Clofifate Quinidine.

Hypoglycemic Agents – Insulin, Chlorpropamide*. Tolbutamide, Glibenclamide,

Phenformin*, Metformin

Coagulants and Anti-Coagulants – Heparin, Thrombin, Menadione*,

Bishydroxycoumarin, Warfarin Sodium.

Local Anesthetics – Lignocaine*, Procaine*, Benzocaine

Histaine and Anti-histamine Agents – Histamine, Diphenhydramine*, Promethazine,

Cyprohetadine, Mepyramine, Pheniramine, Chlorpheniramine*.

Analgesics and Anti-pyretics-Morphin, Pethidine*, Codeine, Methadone, Aspirin*,

Paracetamol*, Analgin, Dextropropoxyphene, Pentazocine.

Non-steroidal anti-inflammatory Agents - Indomethacin*, phenylbutazone*,

oxyphenbutazone, Ibuprofen, Thyroxine and Antithyroids-Thyroxine, Methimazole,
Methylthiouracil, Propylthiouracil.

Diagnostic Agents – Iopanoic Acid, Propyliodone, Sulfobromophthalcin.

Sodium Indigotindisulfonate, Indigo Carmine, Evans blue, Congo Red, Fluoresccin

Sodium.

Anticonvulsants, cardiac glycosides, Antiarryhthmic antihypertensives & vitamins.

Sterioidal Drugs – Betamethazone, Cortisone, Hydrocortisone, prednisolone,
progesterone, Testosterone, Oestradiol, Nandrolone.

Anti-Ncoplasic Drugs-Actinomycins, Azathioprine, Busulphan, Chlorambucil, Cisplatin

cyclophosphamide, Daunorubicin hydrochloride, Flurouracil, Mercaptopurine,
methotrexate, Mytomycin.

Books Recommended : (Latest editions)

1. Pharmocopocia of India
2. British Pharmaceutical Codex
3. Martindale The Extra Pharmacopocia

PRACTICAL (75 HOURS)

CODE ; 241222

1. Systematic qualitative testing of organic drugs involving Solubility determination,

melting point and boiling point, detection of elements and functional groups (10
compounds)
2. Official identification test for certain groups of drugs included in the I.P. like
barbiturates, sulfonamides, phenothiazine, Antibiotics etc. (8 compounds)
3. Preparation of three simple organic preparations.
 CHHATTISGARH SWAMI VIVEKANAND TECHNICAL
UNIVERSITY, BHILAI

Year : 2nd Branch : Diploma in Pharmacy

Subject : Pharmacology & Toxicology Code : 241213

Theory : 75 Hours

Total Marks in End Semester Exam : ……………….

Minimum number of class tests to be conducted : 02

1. Introduction to Pharmacology, scope of Pharmacology.

2. Routes of administration of drugs, their advantages and disadvantages.
3. Various process of absorption of drugs and the factors affecting them,
Metabolism, distribution and excretion of drugs.
4. General mechanism of drugs action and the factors which modify drug action.
5. Pharmacological classification of drugs, The discussion drugs should emphasize
the following aspect :
(i) Drugs acting on the Central Nervous System
(a) General anaesthcies adjuction of anaesthesia, intravenous
anasesthetics.
(b) Analgestic antipyretics and non-steroidal anti-inflammatory
durgs, Narcotic analgesics, Antirheumatic and antigout
remedies, Sedatives and Hyponotics, Psychopharmacological
agents, anti convulsants, analeptics.
(c) Centrally acting muscle relaxants and ant parkinsonism agents
(ii) Local anesthetics
(iii) Drug acting on autonomic nervous system.
(a) Cholinergic drug, Anticholinergic drugs, anticholinesterase
drugs.
(b) Adrenergic drugs and adrenergic receptor blockers
(c) Neuron blockers and ganglion blockers
(d) Neuromuscular blockers, drugs used in myasthenia gravis

(iv) Drugs acting on eye, mydriatics, drugs used in glaucoma

(v) Drugs acting on respiratory system-Respiratory stimulants,
Bronchodilators, nasal decongestants, Expectorants and Antitussive
agents.
(vi) Antacids, Physiological role of histamine and serotonin, Histamine and
Antihistamines, prostaglandins.
(vii) Cardio Vascular drugs, Cardiotonics, Antiarrhythmic agents,
Antianginal agents, Antihypertensive agents, Perpheral Vasodilators
and drugs used in atherosclerosis.
(viii) Drugs acting on the blood and blood forming organs, haematinics,
Coagulants and anti-coagulants, Haemostatics, Blood substitutes and
plasma expanders.
(ix) Drugs affecting renal function, Diuretics and antidiuretics.
 (x) Hormones and hormone antagonists-hypogly ycemic agents,
Antithyroid drugs, Sex hormones and oral contraceptives,
cortcosteroids.
(xi) Drugs acting on digestive system-Carminatives, digestants Bitters,
Antacids and drugs used in Peptic ulcer, purgatives, and laxatives,
Antidiarrhoeals, Emetics, Antiemetics, Anti-spasmodies.
6. Chemotherapy of microbial disease : Urinary antiseptics, Sulphonamides,
Penicillin’s, Streptomycin, Tetracycline’s and other antibiotics, Antitubercular
agents, Antifungal agents, antiviral drugs, antileprotic drugs.
7. Chemotherapy of protozoal diseases, Anthelmintic drugs
8. Chemotherapy of cancer
9. Disinfectants and antiseptics
A detailed study of the action of drugs on each organ is not necessary.

PHARMACOLOGY
PRACTICAL CODE -241223 (50 Hours)

The first six of the following experiments will be done by the students while the
remaining will be demonstrated by the teacher.
1. Effect of K+, Ca++, acetylcholine and adrenaline on frog’s heart.
2. Effect of acetylcholine on rectus abdominis muscle of Frog and guinea pig ileum.
3. Effect of spasmogens and relaxants on rabbits intestine.
4. Effect of local anaesthetics on rabbit cornea.
5. Effect of mydriatics and miotics on rabbits eye.
6. To study the action of strychnine on frog.
7. Effect of digitals on frog’s heart.
8. Effect of hypnotics in mice.
9. Effect of convulsants and anticonvulsant in mice of rats.
10. Test of pyrogen.
11. Taming and hypnosis potentiating effect of chlorpromazine in mice/rats.
12. Effect of diphenhydramine in experimentally produced asthma in guinea pigs.
 CHHATTISGARH SWAMI VIVEKANAND TECHNICAL
UNIVERSITY, BHILAI

Year : 2nd Branch : Diploma in Pharmacy

Subject : Pharmaceutical Jurisprudence Code : 241214

Theory Periods : 50 hours

Total Marks in End Semester Exam : ……………….

Minimum number of class tests to be conducted : 02

1. Origin and nature of Pharmaceutical legislation in India, its scope and objective.
Evolution of the “Concept of Pharmacy” as an integral part of the health Care
System.
2. Principles and significance of Professional Ethics. Critical study of the code of
Pharmaceutical Ethics drafted by Pharmacy Council in India.
3. Pharmacy Act, 1948 – The general study of the Pharmacy Act with special
reference to Education Regulations, working of State and Central Councils,
constitution of these councils and functions. Registration procedures under the
Act.
4. The Drugs and Cosmetics Act, 1940 – General study of the Drugs and Cosmetics
Act and the Rules there under. Definitions and salient features related to retail and
wholesale distribution of drugs. The powers of Inspectors, the sampling
procedures and the procedure and formalities in obtaining licenses under the rule.
Facilities to be provided for running a Pharmacy effectively. General study of the
Schedules with special reference of schedules C, C1 , F, G, J, H, P and X and
salient features of labling and storage condition of drugs.
5. The Drugs and Magic Remedies (Objectionable Advertisement) Act, 1954 -
General study of the Act objectives, special reference to be laid on
Advertisements. Magic remedies and objectionable and permitted advertisements-
disease which cannot be claimed to be cured.
6. Narcotic Drugs and Psychotropic substances Act, 1985-A brief study of the act
with special reference to its objectives, offences and punishment.
7. Brief introduction to the study of the following acts.
i. Latest Drugs (price Control) order in force.
ii. Poisons Act 1919 (as amended to date)
iii. Medicinal and Toilet Preparati0ons (Excise Duties) Act, 1955 (as
amended to date)
iv. Medical Termination of Pregnancy Act. 1971 (as amended to date)

Books Recommended (Latest edition) :

Bare Acts of the said laws published by the Government.
 CHHATTISGARH SWAMI VIVEKANAND TECHNICAL
UNIVERSITY, BHILAI

Year : 2nd Branch : Diploma in Pharmacy

Subject : Drug Store and Business Management Code : 241215

Total Theory Periods : 75 hours

Total Marks in End Semester Exam : ……………….

Minimum number of class tests to be conducted : 02

Part-I Commerce (50 hours)

1. Introduction – Trade, Industry and Commerce Functions and subdivision of
Commerce, introduction to Elements of Economics and Management.
2. Forms of Business Organizations.
3. Channels of Distribution.
4. Drug House Management – Selection of Site Space Lay-out and legel
requirements.
Importance and objectives of Purchasing, selection of suppliers, credit
information, tenders contracts and price determination and legal requirements
thereto.
Codification, handling of drug stores and other hospital supplies

5. Inventory Control-objects and importance, modern techniques like ABC, VED

analysis, the lead time, inventory carrying cost, safety stock, minimum and
maximum stock levels, economic order quantity scrap and surplus disposal.
6. Sales promotion, Market Research, Salesmanship, qualities of a salesman,
Advertising and Window Display.
7. Recruitment, training, evaluation and compensation of the pharmacist.
8. Banking an Finance Service and functions of bank. Finance Planning and sources
of finance

Part-II Accountancy (25 hours)

i. Introduction to the accounting concepts and convention. Double entry book
keeping different kinds of accounts.
ii. Cash Book.
iii. General Léger an trial balance.
iv. Profit and loss account and balance sheet.
v. Simple technique of analyzing financial statements.

Introduction to Budgeting

Books Recommended (latest edition)

Remington’s Pharmaceutical Sciences.

 CHHATTISGARH SWAMI VIVEKANAND TECHNICAL
UNIVERSITY, BHILAI

Year : 2nd Branch : Diploma in Pharmacy

Subject : Hospital and Clinical Pharmacy Code : 241216

Total Theory Periods : 75 hrs

Total Marks in End Semester Exam : ……………….

Minimum number of class tests to be conducted : 02

Part I : Hospital Pharmacy :

1. Hospitals definition, Function, Classification based on various criteria,

Organization Management and Health delivery system in India.
2. Hospital Pharmacy
(a) Definition
(b) Functions and objectives of Hospital Pharmaceutical services.
(c) Location, Layout, Flow chart of material and men.
(d) Personnel and facilities requirements including equipments based on
individual and basic needs.
(e) Requirements and abilities required for Hospital pharmacists.

3. Drug Distribution system in Hospitals :

(a) Out-patient services
(b) In-patient services – (a) types of services (b) detailed discussion of Unit
Dose system, Floor ward stock system, Satellite pharmacy services,
Central sterile services, Bed Side Pharmacy.
4. Manufacturing :
(a) Economical consideration, estimation of demand.
(b) Sterile manufacture-large and small volume parenterals facilities,
requirements, layout production planning, man-power requirements.
(c) Non-sterile manufacture-Liquid orals, externals-bulk concentrates.
(d) Procurement of stores and testing of raw materials.
5. Nomenclature and uses of surgical instruments and Hospital Equipments and
health accessories.
6. P.T.C. (Pharmacy Therapeutic Committee), hospital Formulary System and their
organization, functioning, composition.
7. Drug Information service and Drug Information Bulletin.
8. Surgical dressing like cotton, gauze, bandages and adhesive tapes including their
pharmacopocialcsts for quality, Other hospital supply e.g. I. V. sets B. G. sets,
Ryals tubes, Catheters, Syringes etc.
9. Application of computer in maintenance of records, inventory control, medication
monitoring, Drug information and data storage and retrieval in hospital and retial
pharmacy establishments.
Part – II : Clinical Pharmacy :

1. Introduction to Clinical Pharmacy Practice – Definition, scope.

2. Modern dispensing aspects – Pharmacists and patient counseling and advice for
the use of common drugs, medication history.
3. Common daily terminology used in the Practice of Medicine.
4. Disease, manifestation and pathophysiology including salient symptoms to
understand the disease like Tuberculosis, Hepatitis, Rheumatoid, Arthritis,
Cardiovascular diseases, Epilepsy, Diabetes, Peptic Ulcer, Hypertension.
5. Physiological parameters with their significance.
6. Drug Interactions :
(a) Definition and introduction
(b) Mechanism of Drug Interaction
(c) Drug-drug interaction with reference to analgesics, diuretics,
cardiovascular drugs, Gastro-intestinal agents, Vitamins and
Hypoglycemic agents.
(d) Drug-food interaction.
7. Adverse Drug Reactions :
(a) Definition and Significance
(b) Drug-induced diseases and Teratogenicity
8. Drugs in Clinical Toxicity- Introduction, general treatment of poisoning,
systematic antidotes, Treatment of insecticide poisoning, heavy metal poison,
Narcotic drugs, Barbiturate, Organophosphorus poisons.
9. Drug dependences, drug abuse, addictive drugs and their treatment,
complications.
10. Bio-availability of drugs, including factors affecting it.

Books recommended (latest editors)

1. Remington’s Pharmaceutical Sciences
2. Martindale The Extra Pharmacopocia

PRACTICAL
CODE : 241224

1. Preparation of transfusion fluids.

2. Testing of raw materials used in (1)
3. Evaluation of surgical dressings.
4. Sterilization of surgical instruments, glass ware and other hospital supplies.
5. Handling and use of data processing equipments.