Science10 Q3 Ver4 Mod2
Science10 Q3 Ver4 Mod2
Science10 Q3 Ver4 Mod2
Quarter 3 - Module 2
Feedback Mechanisms in the
Female Reproductive System
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Management Team
Chairperson : Arturo B. Bayocot, PhD, CESO III
Regional Director
Co-Chairpersons : Victor G. De Gracia Jr., PhD, CESO V
Assistant Regional Director
: Randolph B. Tortola, PhD, CESO IV
Schools Division Superintendent
: Shambaeh A. Abantas-Usman, PhD
Assistant Schools Division Superintendent
: Mala Epra B. Magnaong, Chief ES, CLMD
What’s New
Direction: Observe the four pictures and solve the puzzle by working out what the word is.
Every box corresponds to a certain letter. Write your answer in a separate
sheet of paper.
1
What Is It
We have previously discussed that an ovary normally releases only one egg every 28
days. What controls the timing are the hormones. Hormones control many of the changes in
the reproductive system. They also coordinate the development of the ovum and the uterus.
Remember that hormones are chemicals that can affect certain body organs. This cycle
among females occurs every month starting when a female is 10 to 13 years old and it
continues for about 40 years. If an ovum is not fertilized in the fallopian tube, the corpus
luteum degenerates, the progesterone production stops, and the inside membrane of the
uterus breaks down. The breakdown and discharge of the soft uterine tissues and the
fertilized egg is called menstruation. This is the monthly changes or periods that take place
in the female reproductive system.
2
Figure 1.2 The ovary
Source: www.google.com Labeled for Reuse
After the menstrual period, the endometrium starts to build up due to the increasing
amount of estrogen by the developing follicles in the ovary. This is the proliferative phase of
the uterine cycle which lasts for 6 to 14 days. The formation of the corpus luteum and the
secretion of progesterone trigger the endometrium to double in thickness and prepare itself
for a developing embryo. The uterine glands also become mature and they produce a thick
secretion. Hence, the secretory phase of the uterine cycle begins on the 15th day until before
the onset of the next menstrual phase. However, this cycle may be interrupted by stress,
health concerns and pregnancy. But if pregnancy does not occur, the cycle begins anew.
3
What’s More
Direction: Study the diagram below to describe how menstruation occurs and answer the
guide questions that follow.
Guide Questions
Phases
Hormones Involved
4
ACTVITY 2: FROM THE PITUITARY WITH HUGS
Objective
Explain how the hormones are involved in the reproductive systems
Procedure
1. Analyze the picture and take note of your observations.
2. Organize your ideas and explain the roles of hormones in the male and female
reproductive systems.
3. From the following choices, select the appropriate word that would make the
sentences correct. Choose only the CAPITAL LETTER.
A. Hormones D. Ovaries
B. Reproductive System E. Follicles
C. Testes F. Uterus
(1) _____________ play an important role in both the male and female (2)
_____________. The (3) _____________ gland controls the functions of both the (4)
_____________ and (4) _____________. These hormones keep the (5) _____________
working properly.
The production of sperm cells and the release of semen can be regulated by (6)
_____________. The female reproductive system, just like the male reproductive system, is
also regulated by hormones. The (7) _____________ produce hormones that control the
growth and release of eggs from the (8) _____________. While other hormones prepare the
(9) _____________ so a baby can develop and other (10) _____________ still control the
stretching of the uterus during pregnancy.
5
What I Have Learned
Now, let us try to remember the concepts that you have just learned today. Ready,
set, go!
Direction: Answer the following question in complete sentences. (15 points)
What are the functions of the ovaries, follicles, follicle stimulating hormone,
corpus luteum, and progesterone?
What I Can Do
DIFFERENTIATED TASK
Assessment
Direction: Choose the CAPITAL LETTER of the best answer. Write the chosen letter on a
separate sheet of paper.
1. Which days of the cycle does menstruation occur?
A. days 1-6 B. days 7-13 C. days 14-20 D. days 21-28
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2. A biologist made a hypothesis that the pituitary and the ovary both influence the uterine
cycle in females. Which of the following observations would best support this hypothesis?
A. The removal of the pituitary is followed by death.
B. The removal of the ovary can greatly affect the menstrual cycle.
C. The removal of the ovary is followed by a non-functioning pituitary.
D. The uterine development takes place only when both pituitary and ovary are present.
3. A woman’s unsafe period is the day near or during _________.
A. fertilization B. menstruation C. ovulation D. sexual intercourse
4. In a typical 28-day menstrual cycle, on which day following the beginning of the menstrual
period is the level of the luteinizing hormone most likely to be the highest?
A. day 7 B. day 14 C. day 21 D. day 28
5. What happens during ovulation?
A. A sperm can fertilize an egg. C. An ovum is released from the ovary.
B. A zygote becomes an embryo. D. A follicle releases the hormone FSH.
6. Which of the following is responsible for a series of hormonal changes?
A. thyroid gland B. pituitary gland C. parathyroid gland D. thyme gland
7. When does ovulation usually occur?
A. 7th day B. 14th day C. 21st day D. 28th day
8. Why does the endometrium start to build up after the menstruation period?
A. Due to the increasing amount of estrogen
B. Due to the decreasing amount of estrogen
C. Due to the increasing amount of progesterone
D. Due to the decreasing amount of progesterone
9. When does the secretory phase of the uterine cycle begin?
A. 14th day B. 15th day C. 21st day D. 22nd day
10. Which of the following refers to the first menstruation?
A. menstrual cycle C. ovulation
B. menarche D. fertilization
7
Lesson Hormone Feedback and
2 Menstruation
What’s New
Menarche is the most obvious signal of the onset of puberty in females. This is
the first menstrual discharge of
blood from the vagina.
Menarche also signals the
beginning of cyclic changes in
the ovary.
Oocytes that were
unripe or untouched are now
brought up to become active.
Thus, every month, an ovarian
cycle takes place. Figure 2.1
shows the changes in the lining
of the uterus as the month
progresses.
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What Is It
The human ovaries can usually produce only one egg during a 28-day cycle of
activity. The mass of ovarian
cells produces an ovum or an
egg and it also forms a follicle.
The cycle is controlled by FSH
or the Follicle-Stimulating
Hormone. This hormone is
produced in the anterior lobe
of the pituitary gland. The
follicle becomes filled with a
fluid containing the hormone
estrogen when the egg
reaches maturity. Most
importantly, the rising level of
FSH stimulates follicle
maturation and estrogen production.
Figure 2.2 A cross section of the ovary
Figure 2.2 shows the cross section of a human ovary with different stages of
development. As the cycle continues and after the ovum has been discharged, the follicle
turns yellow and it forms the corpus luteum. The yellow body formation is controlled by
another hormone of the pituitary gland called the LH or luteinizing hormone. The corpus
luteum then produces another hormone known as progesterone. Progesterone brings about
effects in the secondary characteristics primarily on the breasts. During pregnancy,
progesterone causes breast enlargement. Moreover, this hormone maintains the growth of
the mucus lining of the uterus.
9
Have you experienced menstrual cramps? Probably yes,
you have. In reality, some females experience menstrual cramps every
month. Did you know that menstrual cramps are the results of the strong
contractions of the uterine wall that occur before and during menstruation?
What do you think is its cause?
Cramps can be caused by the excessive secretion of
prostaglandins. Shedding of the endometrium of the uterus results in the
inflammation of the endometrial layer. As a consequence of this inflammation,
prostaglandins are produced.
In a nutshell, the following summarizes the important events during the menstrual
cycle:
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A feedback mechanism is the process through which the level of a certain
substance influences the level of another substance. A negative feedback affects the
production of hormones in the menstrual cycle. Moreover, high levels of one
hormone may inhibit the production of another hormone. Figure 2.3 presents the
negative feedback mechanisms in the menstrual cycle. Based on the figure, follicle
stimulating hormone or FSH stimulates the ovaries to release estrogen. High levels
of estrogen then prevent more production of FSH. Estrogen then stimulates the
release of luteinizing hormone or LH from the pituitary gland, which in turn, controls
the production of progesterone. Moreover, high levels of progesterone can then
inhibit the further release of LH.
What’s More
Objective
Determine the hormones involved in regulating the processes in the female
reproductive system
Procedure
Check “Yes” if the hormone is involved in regulating the given process, otherwise
check “No”. If your answer is “No”, please state the reason behind it. Write your
answers in the table.
2. Estrogen
3. Antidiuretic Hormone
4. Progesterone
5. Parathyroid Hormone
6. Luteinizing Hormone
7. Epinephrine
8. Follicle Stimulating Hormone
9. Testosterone
10. Melatonin
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ACTIVITY 2: THERE’S A FEEDBACK!
A.
Objective
Describe the feedback mechanisms involved during a menstrual cycle
Materials
2 calendar charts
diagrams of the male and female reproductive systems
scissors
tape or glue
Procedure
Observations:
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B. Study the given pictures to describe the feedback mechanisms involved during the
menstrual cycle and answer briefly the guide questions below.
A B
Guide Questions
1. How long does a menstrual cycle usually last if fertilization has not taken place?
2. Describe what happens to the egg during the first 14 days of the cycle in Part B.
3. Describe what happens to the egg and the uterus during the last 14 days of the
cycle in Part A.
4. What takes place after fertilization?
What I Can Do
DIFFERENTIATED TASK
A. Make a poem about the role of hormones in the female reproductive system.
B. Compose a jingle with lyrics or content talking about the feedback mechanism
in the female reproductive system.
C. Make a poster with a slogan that illustrates the feedback mechanism involved
in the female reproductive system.
D. Produce a newscast about what happens when the body produces more follicle
stimulating hormone and luteinizing hormone.
E. Make a brochure about the feedback mechanism in the female reproductive
system.
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RUBRIC FOR SELF-CHECK
(To be used by the teacher in rating the output)
Assessment
Direction: Choose the CAPITAL LETTER of the best answer. Write the chosen letter on a
separate sheet of paper.
1. Which of the following hormones is responsible for the secondary female characteristics?
A. estrogen B. progesterone C. LH D. FSH
2. Which hormone stimulates the endometrium?
A. estrogen B. progesterone C. LH D. FSH
3. Which of the following inhibits uterine contractions and ovulation?
A. estrogen B. progesterone C. LH D. FSH
4. Which hormone develops and maintains the corpus luteum?
A. estrogen B. progesterone C. LH D. FSH
5. The _________ stimulates the formation of follicles in the ovaries.
A. estrogen B. progesterone C. LH D. FSH
6. It is the process through which the level of a certain substance influences the level of
another substance.
A. FSH B. LH C. menstruation D. feedback
7. An increase in FSH may also indicate a reduction in the production of good quality eggs
and embryos for _________.
A. fertilization B. menstruation C. ovulation D. all of the choices
8. It is an abnormally high levels of LH during non-ovulatory times in the menstrual cycle.
A. menarche B. menopause C. LH D. FSH
9. Which phase signals the beginning of cyclic changes in the ovary?
A. menarche B. menopause C. LH D. FSH
10. The mass of ovarian cells produces a/an _______.
A. sperm B. ovum C. LH D. FSH
11. What hormone does the corpus luteum produce?
A. estrogen B. progesterone C. LH D. FSH
12. What hormone brings about significant effects primarily on the breasts?
A. estrogen B. progesterone C. LH D. FSH
13. During pregnancy, what hormone causes breast enlargement?
A. estrogen B. progesterone C. LH D. FSH
14. What results during strong contractions of the uterine wall?
A. menarche B. menstruation C. menstrual cramps D. AOTC
15. What happens to the cycle after menstruation?
A. The cycle ceases. C. The cycle reverses.
B. The cycle starts again. D. The cycle ends.
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Lesson Hormone Feedback and
3 Pregnancy
What’s New
Now that you have already known about the parts and functions of the human
reproductive system, let us now trace what happens to the ovulated egg to its orderly
sequence of events from the time an egg is ovulated. In this activity, you should be able to
arrange the sequence from the beginning to the end of fertilization and implantation in the
uterus.
Direction: Complete the table below by sequencing the events from the time an egg is
ovulated. Arrange orderly by numbering the items from 1 to 7. Write your answer
inside the table.
Event Sequence
Well done! You were able to perform the activity! You many proceed to the next. Have fun!
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What Is It
As your guide, refer below for the summary of the stages of reproduction:
What is ectopic
pregnancy? Ectopic pregnancy
results if implantation occurs
anywhere other than the uterine
cavity. The most common site of
ectopic pregnancy is in the
fallopian tube. Implantation in
the fallopian tube can be fatal
and can cause the tube to
rupture. In some cases,
implantation can occur in the
mesenteries of the abdominal
cavity and the fetus can develop
normally, but must be delivered
by caesarian section.
As a summary, outlined below are the different processes involved during pregnancy.
Ovulation
This refers to the release of a mature egg from the ovary. It usually takes
place on the 14th day from the first day of menstruation if the cycle is a 28-day cycle.
Fertilization
When a sperm encounters an egg cell in the fallopian tube, it releases
digestive enzymes. Those enzymes clear the path for the sperm nucleus to fuse with
the nucleus of the ovum or egg cell. A zygote is now formed.
Implantation
This occurs before the end of the first week. By this process, the zygote
attaches to the uterine lining, and some of its cells send out projections that has been
part of the maternal tissue. The inner cell mass becomes the embryonic disc. This disc
17
will give rise to the embryo proper during the week following implantation.
Birth or Parturition
“Happy birthday!” is a very common greeting to mark the anniversary of a person’s
birth.
Birth takes place about 39 weeks after fertilization. The birth process begins when
the uterus starts to contract. For the next two to eighteen hours, the contraction becomes
stronger and more frequent. The cervical canal dilates fully and the amniotic sac ruptures.
Birth typically occurs less than an hour after full dilation. Immediately afterward,
uterine contraction forces fluid, blood and the placenta out of the body. The umbilical cord
is now cut, and the newborn embarks on its nurtured existence in the outside world.
What’s More
Objective Trace the processes involved during the release of an egg and fertilization
Procedure
Shade the arrow that correctly traces the processes involved during the release of an
egg. Your answers will guide you to the end of the maze.
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What I Can Do
DIFFERENTIATED TASK
A. Make a poem about the benefits of family planning and post it on your
Facebook account. You may include pictures of your family to
reinforce your point.
B. Select a tweet regarding Responsible Parenthood and Reproductive
Health Act of 2012 and share your thoughts about it. Post it on your
Facebook timeline.
C. Look for a short video about AIDS and help spread awareness and
prevention of AIDS through your social network. You may share it on
your Facebook, Twitter or Instagram accounts.
Assessment
Direction: Choose the CAPITAL LETTER of the best answer. Write the chosen letter on a
separate sheet of paper.
1. Which hormone prevents menstruation among pregnant women?
A. HCG B. LH C. oxytocin D. prolactin
2. HCG which is secreted by the chronic membrane is similar in structure and function to
______.
A. FSH B. LH C. estrogen D. progesterone
3. How many hours will the egg cell be viable for fertilization?
A. 12 hours B. 24 hours C. 48 hours D. 72 hours
4. The egg will most likely be fertilized while it is travelling in the ______.
A. cervix B. fallopian tube C. uterus D. vagina
5. What is formed when a sperm successfully penetrates the nuclei fuse?
A. egg B. sperm C. ovum D. zygote
6. Upon successful implantation of a developing embryo in the endometrium, the developing
embryo and the uterine lining jointly forms a special organ called the ______.
A. cervix B. fallopian tube C. placenta D. uterus
7. Where are egg cells found?
A. ovary B. uterus C. placenta D. vagina
8. What results if implantation occurs anywhere other than the uterine wall?
19
A. menarche B. menopause C. ectopic pregnancy D. miscarriage
9. What occurs before the end of the first week by which the zygote attaches to the uterine
lining?
A. menstruation B. fertilization C. implantation D. ovulation
10. This secreted hormone provides nourishment to the embryo.
A. LH B. FSH C. HCG D. all of the choices
11. Sperm cells are released into the ________ during mating.
A. ovaries B. uterus C. fallopian tube D. vagina
12. What does the ovary release every month?
A. egg B. sperm C. LH D. FSH
13. What will drop if the embryo is abnormal or if it dies?
A. HCG B. LH C. FSH D. all of the choices
14. Which of the following results to the disintegration of endometrium?
A. menarche B. menopause C. menstruation D. miscarriage
15. Which of the following is the most common site of ectopic pregnancy?
A. ovaries B. fallopian tube C. uterus D. vagina
Direction: Choose the CAPITAL LETTER of the best answer. Write the chosen letter on a
separate sheet of paper.
1. Which days of the cycle does menstruation occur?
A. days 1-6 B. days 7-13 C. days 14-20 D. days 21-28
2. A biologist made a hypothesis that the pituitary and the ovary both influence the uterine
cycle in females, which of the following observation would best support this hypothesis?
A. The removal of pituitary is followed by death.
B. The removal of the ovary can greatly affect the menstrual cycle.
C. The removal of the ovary is followed by a non-functioning pituitary.
D. The uterine development takes place only when both pituitary and ovary are present.
3. A woman’s unsafe period is the day near or during _________.
A. fertilization B. menstruation C. ovulation D. sexual intercourse
4. In a typical 28-day menstrual cycle, on which day following the beginning of the menstrual
period is the level of luteinizing hormone most likely to be the highest?
A. day 7 B. day 14 C. day 21 D. day 28
5. What happens during ovulation?
A. A sperm can fertilize an egg. C. An ovum is released from the ovary.
B. A zygote becomes an embryo. D. A follicle releases the hormone FSH.
6. It is the process through which the level of a certain substance influences the level of
another substance?
A. FSH B. LH C. menstruation D. feedback
7. An increase in FSH may also indicate a reduction in the production of good quality eggs
and embryos for _________.
A. fertilization B. menstruation C. ovulation D. all of the choices
8. It is an abnormally high levels of LH during non-ovulatory times in the menstrual cycle.
A. menarche B. menopause C. LH D. FSH
20
9. What signals the beginning of cyclic changes in the ovary?
A. menarche B. menopause C. LH D. FSH
10. Which of the following is produced by the mass of ovarian cells?
A. sperm B. ovum C. LH D. FSH
11. Where are the sperm cells released during mating?
A. ovaries B. uterus C. fallopian tube D. vagina
12. What does the ovary release every month?
A. egg B. sperm C. LH D. FSH
13. If the embryo is abnormal or if it dies, _______ will drop.
A. HCG B. LH C. FSH D. all of the choices
14. What results to the disintegration of the endometrium?
A. menarche B. menopause C. menstruation D. miscarriage
15. Which of the following is the most common site of ectopic pregnancy?
A. ovaries B. fallopian tube C. uterus D. vagina
21
22
ASSESSMENT (UNIT Assessment
What I know What's More
TEST) 1. A
1. A 2. B
1. D 2. B 3. B
2. B 3. B Activity 4. A
3. C 4. A 5. D
4. B 5. D 6. C
5. A 6. C 7. A
6. D 7. A 8. C
7. A 8. C 9. C
8. B 9. C 10.C
9. A 10.C 11.D
10. B 11.D 12.A
11. D 12.A 13.A
12. A 13.A 14.D
13. A 14.D
14. D 15.B
15.B
15. B
Lesson 3
What’s More
Activity 1
What I Know Assessment
1. No- synthesis of sex
steroids
1. A 2. Yes 1. A
3. No- increases water
2. B absorption
2. B
3. B 4. Yes 3. B
5. No- stimulates
4. C Calcium uptake 4. C
5. D 6. Yes 5. D
7. No- increase heart
6. D rate, blood pressure 6. D
and blood sugar
7. A 8. Yes
7. A
8. B 9. No- male development 8. B
10. No- blocks secretion
9. A of LH and FSH, 9. A
10.B promotes sleep 10.B
11.B Activity 2 11.B
12.B 1. 28 days
12.B
13.B 2. It moves out of the 13.B
uterus
14.C 3. The egg is fertilized
14.C
15.B and attaches to the 15.B
uterus for implantation
4. Implantation
Lesson 2
Assessment
What’s More
1. D
What I Know Phases/Hormone 2. B
3. C
1. D 1. Blood Flow- None 4. B
2. Follicular- Estrogen
2. B 3. Ovulation- None
5. A
4. Luteal- Estrogen and 6. B
3. C Progesterone 7. B
4. B 8. A
The egg travels through a 9. B
5. A thin tube called a fallopian
tube of the uterus. If the egg 10.B
6. B is fertilized by a sperm cell, it 11.B
7. B attaches to the wall of the 12.C
uterus, where overtime
8. A develops into a baby. If the 13.B
9. B egg is not fertilized, the 14.A
uterus lining breaks down 15.D
10.B and bleeds causing a period.
11.B 1. d
2. e
Lesson 1
12.C
3. h
13.B 4. g
14.A 5. c
6. b
15.D 7. a
8. f
Answer Key