Word Cycle

1. What word or objects can you associate with the word cycle?
CYCLE
2. Give examples of a life cycle.
Okay. Thank you for the amazing answers class. Later on, we will know what is the connection of this
cycle and how vital it is to human life.
Before we proceed to our lesson, let’s have our group activity.
Activity 2: Arrange ME!
Directions:
1. Group the class into 2 groups. Choose a leader each group and right the name of their members in
a ¼ sheet of paper.
2. The teacher will give each group a card-stick that contain phases of cell cycle.
3. Each group will assign a member to hold the stick card and will provide a statement that describe
how that certain phase works. Explanation should not exceed in 2 sentences.
4. All representative chosen per group will form a cycle/circle and arrange themselves according to
how cell cycle works. They can base their answers on their modules.
5. Students must be creative on how they will insert the checkpoints per phases.
6. Students will be given 10 minutes to prepare and 2 minutes to present.
SCORING RUBRICS:
Organization – 5 pts
Creativity – 5 pts
Presentation of each phase – 10 pts
TOTAL – 20 PTS
Unicellular
Organism (e.g.,  INTERPHASE
bacteria)
- Portion of the cell cycle preceding
- Cellular division
mitosis in which the cell grows and
is a means to
carries out life functions.
produce
offspring. - Longest phase of cell cycle.
- Bacterial cells 3 SUB-PHASES
divide, through a
type of cell 1. G1 (Growth or Gap1) Phase
division called - Cell grows in size
binary fission. - Organelles are formed
- RNA, proteins, and enzymes needed
for making DNA are synthesized.
Multicellular 2. S (Synthesis) Phase
Organisms
- Replication of DNA
- Cellular division
- At the end of this stage, each
is a means for
the production of chromosome is made up of two sister
new tissues or chromatids attached at the
body parts during centromere.
growth and 3. G2 (Growth or Gap2) Phase
development. - Final preparation of the cell for
- Even after birth, division
cells continue to - Assembly of proteins such as
divide for microtubules
continuous
growth and
development of
 M (Mitosis or Meiosis) Phase
tissues.
- The cell undergoes division
Replace worn-out and damaged cells - The nucleus and the cytoplasm were
- The epithelial cells that are sloughed-off when you rub divided
your skin with a towel after taking a bath are replaced
with new epithelial cells.  Control of the Cell Cycle
- Cells in the digestive and respiratory tracts are also Signal – a molecule that stimulates or
replaced by cell division every time they are damaged. inhibits a metabolic event. These
- Cellular division is a means to produce new individuals signals ensure that the stages follow
in asexually-reproducing organisms (e.g., stem cutting of one another in the normal sequence
santan stem, and formation of a bud). and that each stage is properly
completed before the next stage
begins.
Cell Cycle Checkpoints

- It will tell the cell to either “stop” or
“go” to the next stage.
 G1 Checkpoint – ensures that the cell is ready to undergo DNA synthesis or phase.
 G2 Checkpoint – makes sure that the cell is mature enough to undergo M phase.
 M Checkpoint – sees to it that the cell is ready to complete cell division.
NOTE:
 In instances when the cell cycle checkpoints detect abnormalities, the cell is instructed not to
proceed to the next stage but instead repair the abnormality.
 When the abnormality or damage is beyond repair, the cell undergoes programmed cell death,
called apoptosis.
 These mechanisms ae important to ensure that all daughter cells produced are of normal structure
and function.
 However, there are cases when the cell cycle checkpoints are not fully functioning and thus the
quality of the cells produced are not properly controlled.
 Such malfunctions may result in unregulated cell division, which might lead to cancer.
 Uncorrected mistakes in the cell cycle, including DNA damage and mutations or improper
chromosomal segregation and aneuploidy, result in genomic instability, a distinct characteristic of
cancer.
Cancer – an abnormal growth of cells that has malignant characteristics. Cancer cells fail to respond to
the signals that regulate the growth of cells. They can spread throughout the body; thus, the normal
functions are distributed causing serious medical problems and eventually death.

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1. What word or objects can you associate with the word cycle?

2. Give examples of a life cycle.

Before we proceed to our lesson, let’s have our group activity.

Activity 2: Arrange ME!

Presentation of each phase – 10 pts

Cell Cycle Checkpoints

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