Gametogenesis
Gametogenesis
Gametogenesis
Today’s Objectives
• Identify the process by which meiotic
divisions lead to both male and female
mammalian gametes
• Identify the following important
components of the process of fertilization:
gametes, spermatogonia, flagellum,
tubulin, oocyte, pronuclei, vitelline
membrane, zona pellucida
Gametogenesis
• Process of creating gametes
• Germ cells are set aside early in
development
• Migrate to the gonad
• Undergo meiotic divisions to make haploid
germ cells
Meiosis - A review
• What is the ploidy of the somatic cell that will
undergo meiosis to form gametes?
• How many cell divisions take place?
• What happens to the genome before the first
division?
• What are the phases in each meiotic division?
• How many daughter cells are made?
• What is the ploidy of those daughter cells?
Gametogenesis in Mammals
• Spermatogenesis
– Process of producing sperm
– Occurs in seminiferous tubules of
the testes
• Oogenesis
– Process of producing oocytes
– Occurs in ovaries
Spermatogenesis
1) Spermatogonia are the germ cells that will eventually
develop into the mature sperm; the first step in this
development is the duplication of homologous
chromosomes to get ready for meiosis
2) Primary spermatocyte :the first meiotic division separates
the homologous chromosomes from each parent
3) Secondary spermatocyte :the second meiotic division
separates the 2 chromatids and creates 4 haploid cells
4) Spermatids: Will produce 4 sperm cells by the process of
spermiogenesis.
Sperm cells differentiate into the shape we commonly
know(will talk more about structure next time)
Simplified view
of
spermatogenesis
Oogenesis
1) Oogonia are the germ cells that will eventually
develop into the mature oocytes
2) Primary oocyte : Undergoes the first meiotic
division, separating homologous chromosomes
3) Secondary oocyte :the second meiotic division
separates the 2 chromatids and creates 4 haploid
cells
4) Egg:
• In females, it produces 1 egg (ovum) and 3 polar
bodies. This allows the egg to retain more cytoplasm
to support early stages of development
Implantation in
uterine wall
Sperm must
pass through
the uterus
2nd
Sperm Enters
the vagina 1st
Oviduct
Fertilization occurs here
Zygote
• Zygote is a fertilized
egg.
• A fertilized egg
becomes an embryo
as soon as the first
cleavage occurs.
Internal Ferilization
• Chance of zygote
survival is increased
greatly
External Fertilization
• Zygotes chance of
survival decreases
significantly