Andrew N. Lane, PhD
About
Faculty Rank
- Professor
Research
Research Focus
Cancer biochemistry.
Programs
Translational OncologyCollege & Department
Contact Information
525 Lee T. Todd, Jr. Building - Biopharm Complex
789 S. Limestone St
Lexington, KY 40536
United States
Phone
Email
Publications
- Stability and kinetics of G-quartet structuresLane, A.N.* Chaires, J.B., Gray, R.D. & Trent, J.O. (2008) Nucl. Acids Res. 36, 5482-5515. Survey & Summary Review.doi: 10.1093/nar/gkn517. PMCID: PMC2553573
- Myc induction of hypoxic glutamine metabolism and a glucose-independent TCA cycle in human B lymphocytes.Le, A., Lane, A.N.#, Hamaker, M., Bose, S., Barbi, J., Tsukamoto, T., Rojas, C.J., Slusher, B.S., Zhang, H., Zimmerman. L.J., Liebler, D.C., Slebos, R.J.C., Lorkiewicz, P.K., Higashi, R.M., Fan, T.W-M., and Dang, C.V. (2012) Cell Metabolism. 15, 110-121 doi:10.1016/j.cmet.2011.12.009. PMCID:PMC3345194
- Pyruvate carboxylase is upregulated in NSCLC.Sellers, K., Fox, M.P., Bousamra, M., Slone, S., Higashi, R.M.,Miller, D.M., Wang, Y., Yan, J., Yuneva, M., Deshpande, R., Lane, A.N., Fan, T. W-M. (2015) J. Clin Invest. 125: 687-698
- Regulation of nucleic acid metabolism in mammalian cells.Lane, A.N. & Fan,T-WM. (2015) Nucl.Acids Res. 43, 2466-85
- X-ray crystallography and NMR show that 5-formylcytosine does not change the global structure of DNA.Hardwick, J.S., Ptchelkine , D., El Sagheer, A.H., Tear, I., Singleton, D., Phillips, S.E.V., J., Lane, A.N., Brown, T. (2017) Nat. Struct. Biol. 24,544–552
- Structure-based profiling of Metabolites and Isotopomers by NMR, Prog.Fan, T.W-M. & Lane, A.N. (2008) NMR Spectrosc. 52, 69-117 doi:10.1016/j.pnmrs.2007.03.002
- Altered Regulation of Metabolic Pathways in Human Lung Cancer Discerned by 13C Stable Isotope-Resolved Metabolomics (SIRM).Fan, T.WM., Lane, A.N., Higashi, R.M., Farag, M.A., Gao, H., Bousamra, M. & Miller, D.M. (2009) Molecular Cancer. 8:41 doi:10.1186/1476-4598-8-41. PMCID: PMC2717907
- Isotopomer-based metabolomic analysis by NMR and mass spectrometry.Lane, A.N.*, Fan, T-WM. & Higashi, R.M. (2008) Methods in Cell Biology, Vol 84. Biophysical Tools for Biologists, Volume 1, edited by Drs. John J. Correia and H. William Detrich. Elsevier Science & Technology Books Ch. 18. pp 541-588. ISBN: 9780123725202