Drug Study BISACODYL
Drug Study BISACODYL
Drug Study BISACODYL
Generic Name Pharmacologic Class: Stimulates peristalsis by General Indications Contraindications GI: abdominal cramps, Before
Bisacodyl Stimulant laxatives directly irritating the smooth -treatment for Hypersensitivity, abdominal pain, nausea, diarrhea, rectal -Check for the doctor’s order
muscle of the intestine, constipation obstruction, N/V burning -Confirm patient’s identity
Trade Name Therapeutic Class: possibly the colonic -Prepare the medicine
Dulcolax laxatives intramural plexus; alters Patients Actual Precautions F&E: hypokalemia -Assess patient for abdominal distension, presence
water and electrolyte Indication Use cautiously in severe (chronic use) of bowel sounds and usual pattern of bowel
Patients Dose Pregnancy Risk secretion producing net -treatment for cardiovascular disease, and or rectal function.
1 tab BID Category: intestinal fluid accumulation constipation fissures, excess or prolonged use, MS: muscle weakness -Assess patient’s and family’s knowledge of drug
B and laxation. . products containing tannic acid, (chronic use) therapy
Availability should not be used as multiple
Enteric-coated tablets: 5 Pharmacokinetics enemas, may be used during MISC: protein-losing During
mg OTC Absorption: pregnancy & lactation. enteropathy, tetany -Administer at bedtime for morning results
Enteric-coated and Minimal from the GI tract (chronic use) -P.O: taking on an empty stomach will produce
delayed release: 5mg (oral, as enteric-coated Drug interactions more rapid results.
OTC tablets/suppositories). Milk: may remove enteric coating at -Do not crush or chew enteric coated tablets. Take
tablets, resulting in gastric with full glass of water or juice
Routes of administration Metabolism: irritation/dyspepsia -Do not administer oral doses within 1 hr of milk or
P.O Converted to bis(p- antacid causes gastric irritation
hydroxyphenyl)pyridyl-2- -Consider rights of drug administration
methane by intestinal or
bacterial enzymes. After
-Advise patient that laxatives should be used only
Excretion: for short-term therapy. Prolonged use may lead to
Faeces; urine (as electrolyte imbalance & dependence.
glucuronide). -Advise to increase oral fluid intake to 1500-2000
ml/day to prevent dehydration
Onset: -Encouraged pt. to use other forms of bowel
regulation
oral : 6 to 12 hours
-Advise pt. that bisacodyl should not be used when
rectal: 20 to 60 minutes constipation is accompanied by abdominal pain,
fever, N/V
Drug Half Life: 8 hours - Report any signs of unusualities
Source: Davis drug guide, Source: Davis drug Source: Davis drug guide, 9th Source: Davis drug Source: Davis drug guide, 9th ed pg. Source: Davis drug Source:Davis drug guide, 9th ed pg. 117-118
9th ed pg. 116 guide, 9th ed pg. 117 ed pg. 117 guide, 9th ed pg. 117 117 guide, 9th ed pg. 117