UGC CBCS

TDC COURSE CURRICULUM

and
SYLLABI
(As per UGC’s Draft Model
Syllabi)
(PROPOSED SCHEME)

CHEMISTRY
UGC’s Draft Model Syllabi)
(PROPOSED SCHEME)
Submitted by:-
Dr. Pradip C. Paul
Head, Department of Chemistry
Chairman, BUGS-Chemistry
Assam University: Silchar.

Adopted in the meeting of the BUGS-Chemistry dated April 20, 2017.

Modified as per CBCS Syllabus Structure Preparation Committee Meeting,
March 28, 2017
 Contents
1. CBCS UG - Course Curriculum – Basic Structure

2. CBCS UG – SYLLABI for CHEMISTRY (HONOURS)

a) Semester-Wise Course Structure for Choice Based Credit System In B. Sc. Honours
(Chemisry)

b) Core Courses for Chemistry (Honours) with Course Code and Course Name

c) Discipline Specific Elective (DSE) Courses for Chemistry Honours

d) Skill Enhancement Courses (SEC)

e) Semester wise list of Chemistry Generic Elective papers for the students taking Honours in
other disciplines

3. CBCS –Syllabi for B. Sc. with Chemistry

a) Semester-Wise Course Structure for Choice Based Credit System in B. Sc. with Chemistry

b) Semester wise list of Chemistry papers to be studied as Discipline Specific Core (DSC)
Courses by students of BSc with Chemistry

c) Discipline Specific Elective (DSE) Courses

d) Skill Enhancement Courses (SEC)

4. Detailed Syllabi

a) Core Courses

b) Discipline Specific Elective (DSE) Courses

c) Skill Enhancement Courses (SEC)

Important Note:
Course content, Question Papers and Schedule of Examination shall be the same for DSC
[Core for BSc with Chemistry] and GE [Hons with other Discipline] in accordance with
sections 2.3, 2.1 and 3.2 of UGC’s Instructional Template for facilitating implementation of
CBCS.

Reference:
UGC’s Instructional Template for Facilitating Implementation of CBCS
2.3 P.S.: A core course offered in a discipline/subject may be treated as an elective by
other discipline/subject and vice versa and such electives may also be
referred to as Generic Elective (GE).
2.1 Discipline Specific Elective (DSE) (4 for Honours and 2 for Regular courses)
3.2 Skill Enhancement Courses (SEC) (2 for Honours and 4 for Regular courses).
 CBCS UG - COURSE CURRICULUM (Basic structure)
B.Sc. (Honours)
CHEMISTRY (HONOURS)

CORE COURSE (C) Papers x Credits Total Credits

CHEMISTRY x
CORE 14 4+2 84
Theory + Practical
ELECTIVE COURSE (DSE and GE)
DSE Chemistry Theory + Practical 4 x 4+2 24
Theory + Practical 4 x 4+2
GE or or 24
Theory + Tutorial 4 x 5+1
GE Courses are Computer Science, Mathematics, Physics (any one).
Ability Enhancement Courses
Ability Enhancement Compulsory Courses (AECC)
1) English/MIL Communication 2 x 4 08
2) Environmental Science
Skill Enhancement Courses (SEC) 2 x 4 08
Total Credits = 148

CBCS UG - Course Curriculum

B. Sc. with Chemistry
Discipline Specific Core (DSC) Courses Papers x Credits Total Credits
DSC 1: Chemistry Theory + Practical 4 x 4+2
DSC 2: other subject Theory + Practical 4 x 4+2
DSC DSC 3: other subject Theory + Practical 4 x 4+2 72
or
DSC 3: other subject Theory+Tutorial 4 x 5+1
Discipline Specific Elective (DSE) Courses
DSE 1: Chemistry Theory + Practical 2 x 4+2
DSE 2: other subject Theory+Practical 2 x 4+2
DSE DSE 3: other subject Theory+Practical 2 x 4+2 36
or
DSC E: other subject Theory+Tutorial 2 x 5+1
Skill Enhancement Courses (SEC) 4 x 4 16
Ability Enhancement Compulsory Courses 2 x 4 08
(AECC)
1) English/MIL Communication
2) Environmental Science
Total Credits = 132
Each credit is equivalent to 1 hour of activity per week
 CBCS
TDC - SYLLABI

CHEMISTRY
(HONOURS)
 SEMESTER-WISE COURSE STRUCTURE FOR CHOICE BASED CREDIT SYSTEM IN
B. Sc. Honours (CHEMISRY)

CORE COURSE Ability Enhancement Ability Enhancement Elective: Discipline Elective:

(14 papers) Compulsory Course Elective Course(AEEC) Specific DSE Generic(GE)
(AECC) (Skill Based) (4 papers) 4 papers
(2 papers) (2 papers) (To be taken from
other discipline)

I CHEMISTRY-C-101 GE-1

Environmental
CHEMISTRY -C-102 Science

II CHEMISTRY -C-201 GE-2

English/MIL
CHEMISTRY -C-202 Communication

III CHEMISTRY -C-301 CHEMISRY-SEC-301 GE-3

CHEMISTRY -C-302

CHEMISTRY -C-303

IV CHEMISTRY -C-401 CHEMISRY-SEC-401 GE-4

CHEMISTRY -C-402

CHEMISTRY -C-403

V CHEMISTRY -C-501 CHEMISRY-DSE-501

CHEMISTRY -C-502 CHEMISRY-DSE -502

VI CHEMISTRY -C-601 CHEMISRY-DSE -601

CHEMISTRY -C-602 CHEMISRY-DSE -602

 Core Courses for Chemistry (Honours) with Course Code and Course Name

SEMESTER Course No. Course Name Credit Marks

CHEMISTRY-C-101 Inorganic Chemistry –I 4 70
Atomic Structure and Chemical Bonding
CHEMISTRY-C-101-LAB Practical 2 30
I 4

CHEMISTRY-C-102 Physical Chemistry –I 4 70

States of Matter and Ionic Equilibrium
CHEMISTRY-C-102-LAB Practical 2 30
CHEMISTRY-C-201 Organic Chemistry –I 4 70
Hydrocarbons and Stereochemistry
CHEMISTRY-C-201-LAB Practical 2 30
II
CHEMISTRY-C-202 Physical Chemistry –II 4 70
Chemical Thermodynamics and its Applications
CHEMISTRY-C-202-LAB Practical 2 30
CHEMISTRY-C-301 Inorganic Chemistry –II 4 70
s- & p-block Elements and Metallurgy
CHEMISTRY-C-301-LAB Practical 2 30
CHEMISTRY-C-302 Organic Chemistry –II 4 70
Halogen & Oxygen Containing Functional
III Groups
CHEMISTRY-C-302-LAB 2 30
Practical
CHEMISTRY-C-303 Physical Chemistry –III 4 70
Phase Equilibria and Chemical Kinetics
CHEMISTRY-C-303-LAB Practical 2 30
CHEMISTRY-C-401 Inorganic Chemistry –III 4 70
Coordination Chemistry and its Applications
CHEMISTRY-C-401-LAB Practical 2 30
CHEMISTRY-C-402 Organic Chemistry –III 4 70
IV Heterocyclic Chemistry
CHEMISTRY-C-402-LAB Practical 2 30
CHEMISTRY-C-403 Physical Chemistry –IV 4 70
Electrochemistry
CHEMISTRY-C-403-LAB Practical 2 30
CHEMISTRY-C-501 Organic Chemistry –IV 4 70
Biomolecules
CHEMISTRY-C-501-LAB Practical 2 30
V
CHEMISTRY-C-502 Physical Chemistry –V 4 70
Quantum Chemistry and Spectroscopy
CHEMISTRY-C-502-LAB Practical 2 30
CHEMISTRY-C-601 Inorganic Chemistry –IV 4 70
Organometallic Chemistry
CHEMISTRY-C-601-LAB Practical 2 30
VI
CHEMISTRY-C-602 Organic Chemistry –V 4 70
Spectroscopy, Dyes and Polymers
CHEMISTRY-C-602-LAB Practical 2 30
 Discipline Specific Elective (DSE) Courses forChemistry Honours

SEMESTER COURSE No. Couse Name Credit Marks

CHEMISTRY-DSE-501 Analytical Methods in Chemistry 4 70

CHEMISTRY-DSE-501-LAB Practical 2 30
V

CHEMISTRY-DSE-502 Green Chemistry 4 70

CHEMISTRY-DSE-502-LAB Practical 2 30

Inorganic Materials of Industrial

CHEMISTRY-DSE-601 Importance 4 70

VI CHEMISTRY-DSE-601-LAB Practical 2 30

CHEMISTRY-DSE-602 Dissertation (Project Work) 6 100

Skill Enhancement Courses (SEC)

(FOR CHEMISTRY HONOURS)

III CHEMISTRY-SEC-301 Analytical Clinical Biochemistry 4 70

IV CHEMISTRY –SEC-401 Fuel Chemistry 4 70

Semester wise list of Chemistry Generic Elective (GE) papers for the students
taking Honours in other disciplines

COURSE No.
SEMESTER Credit Marks
Course Name
CHEMISTRY-GE-101 4 70
Atomic Structure, Bonding, General Organic
I Chemistry and Aliphatic Hydrocarbons
CHEMISTRY-GE-101-LAB 2 30
Practical
CHEMISTRY-GE-201 4 70
Chemical Energetics, Equilibria and
II Functional Group Organic Chemistry-I
CHEMISTRY-GE-201-LAB 2 30
Practical
CHEMISTRY-GE-301 4 70
Solutions, Phase Equilibrium,
Conductance, Electrochemistry and
Functional Group Organic Chemistry-II
III
CHEMISTRY-GE-301-LAB 2 30
Practical
CHEMISTRY-GE-401 4 70
Transition metals, Coordination Chemistry,
IV States of Matter and Chemical Kinetics
CHEMISTRY-GE-401-LAB 2 30
Practical
 CBCS
TDC - SYLLABI

B. Sc. with
CHEMISTRY
 SEMESTER-WISE COURSE STRUCTURE FOR CHOICE BASED CREDIT SYSTEM IN
B. Sc. with Chemistry

DISCIPLINE SPECIFIC Ability Enhancement Skill Discipline Specific

CORE Compulsory Enhancement Course (SEC) Elective (DSE)
COURSE (DSC) Course(AECC) (4 papers) (6 papers)
(12 papers) (2 papers)

CHEMISTRY-DSC-101 Environmental
Science
I DSC- 2 A
DSC- 3 A
CHEMISTRY-DSC-201 English/MIL
Communication
II DSC- 2 B
DSC- 3 B

CHEMISTRY-DSC-301 CHEMISTRY-SEC-301
III DSC- 2 C
DSC- 3 C
CHEMISTRY-DSC-401 CHEMISTRY-SEC-401

IV DSC- 2 D
DSC- 3 D

CHEMISTRY-SEC-501 CHEMISTRY-DSE-501
V DSE-2 A
DSE-3 A

CHEMISTRY-SEC-601 CHEMISTRY-DSE-601

VI DSE-2 B
DSE-3 B
 CBCS: B. Sc. with Chemistry
Semester wise list of Chemistry papers to be studied as Discipline Specific Core (DSC) Courses by
students of BSc with Chemistry (Regular)
COURSE No.
SEMESTER Credit Marks
Course Name
CHEMISTRY-DSC-101 4 70
Atomic Structure, Bonding, General Organic Chemistry and
I Aliphatic Hydrocarbons
CHEMISTRY-DSC-101-LAB 2 30
Practical
CHEMISTRY-DSC-201 4 70
Chemical Energetics, Equilibria and
II Functional Group Organic Chemistry-I
CHEMISTRY-DSC-201-LAB 2 30
Practical
CHEMISTRY-DSC-301 4 70
Solutions, Phase Equilibrium, Conductance, Electrochemistry
and Functional Group Organic Chemistry-II
III
CHEMISTRY-DSC-301-LAB 2 30
Practical
CHEMISTRY-DSC-401
Transition metals, Coordination Chemistry, 4 70
IV States of Matter and Chemical Kinetics
CHEMISTRY-DSC-401-LAB 2 30
Practical

Discipline Specific Elective (DSE) Courses

CHEMISTRY-DSE-501 4 70
Analytical Methods in Chemistry
V
CHEMISTRY-DSE-501-LAB 2 30
Practical
CHEMISTRY-DSE-601 4 70
Inorganic Materials of Industrial Importance
VI
CHEMISTRY-DSE-601-LAB 2 30
Practical
Skill Enhancement Courses (SEC)
CHEMISTRY-SEC-301 4 70
III
Analytical Clinical Biochemistry
CHEMISTRY-SEC-401 4 70
IV Fuel Chemistry
CHEMISTRY-SEC-501 4 70
V
Chemistry of Cosmetics and Perfumes
CHEMISTRY-SEC-601 4 70
VI Pesticide Chemistry

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 7 of 99

 Detailed Syllabi

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 8 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(1st Semester)
Course No.:CHEMISTRY-C-101
(Inorganic Chemistry – I)
Atomic Structure & Chemical Bonding
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)
Objective of thiscourse is to emphasize on Atomic structure, bonding and periodicity

Unit 1: Atomic Structure

Bohr’s theory, its limitations and atomic spectrum of hydrogen atom. Wave mechanics: de
Broglie equation, Heisenberg’s Uncertainty Principle and its significance, Schrödinger’s
wave equation, significance of  and 2. Quantum numbers and their significance.
Normalized and orthogonal wave functions. Sign of wave functions. Radial and angular wave
functions for hydrogen atom. Radial and angular distribution curves. Shapes of s, p, d and f-
orbitals. Contour boundary and probability diagrams.
Pauli’s Exclusion Principle, Hund’s rule of maximum multiplicity, Aufbau’s principle and its
limitations.

Unit 2: Periodicity of Elements

s, p, d, f block elements, the long form of periodic table. Detailed discussion of the
following properties of the elements, with reference to s&p block.
(a) Effective nuclear charge, shielding or screening effect, Slater rules, variation of
effective nuclear charge in periodic table.
(b) Atomic radii (van der Waals)
(c) Ionic and crystal radii.
(d) Covalent radii (octahedral and tetrahedral)
(e) Ionization enthalpy, Successive ionization enthalpies and factors affecting ionization
energy. Applications of ionization enthalpy.
(f) Electron gain enthalpy, trends of electron gain enthalpy.
(g) Electronegativity, Pauling’s/ Mulliken’s/ Allred Rachow’s electronegativity scales.
Variation of electronegativity with bond order, partial charge, hybridization, group
electronegativity.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 9 of 99

Unit 3: Chemical Bonding I
(i) Ionic bond: General characteristics, types of ions, size effects, radius ratio rule and its
limitations. Packing of ions in crystals. Madelung constant, Born-Haber cycle and its
application, Solvation energy.
(ii) Covalent bond: Lewis structure, Valence Bond theory (Heitler-London approach).
Energetics of hybridization, equivalent and non-equivalent hybrid orbitals. Resonance and
resonance energy, Molecular orbital theory. Molecular orbital diagrams of diatomic and
simple polyatomic molecules N2, O2, C2, B2, F2, CO, NO, and their ions; HCl, BeF2, CO2,
(idea of s-p mixing and orbital interaction to be given). Formal charge, Valence shell electron
pair repulsion theory (VSEPR), shapes of simple molecules and ions containing lone pairs
and bond pairs of electrons, multiple bonding (σ and π bond approach) and bond lengths.

Unit 4: Chemical Bonding II

(i) Ionic character in covalent compounds: Bond moment and dipole moment. Percentage
ionic character from dipole moment and electronegativity difference.
(ii) Covalent character in ionic compounds, polarizing power and polarizability. Fajan’s
rules and consequences of polarization.
(iii) Metallic Bond: Qualitative idea of valence bond and band theories. Semiconductors and
insulators, defects in solids.
(iv) Weak Chemical Forces: van der Waals forces, ion-dipole forces, dipole-dipole
interactions, induced dipole interactions, Instantaneous dipole-induced dipole
interactions. Hydrogen bonding (theories of hydrogen bonding, valence bond
treatment).

Unit 5: Oxidation-Reduction
Redox reactions, balancing Redox equations by ion-electron method Standard Electrode
Potential and its application to inorganic reactions, concept of formal Electrode Potential
Principles involved in volumetric analysis: Fe estimation by standard KMnO4 solution, and
K2Cr2O7 solution.

Reference Books:
 Lee, J. D. Concise Inorganic Chemistry, ELBS, 1991.
 Douglas, B. E. and Mc Daniel, D. H., Concepts & Models of Inorganic Chemistry,
Oxford, 1970
 Atkins, P. W. & Paula, J. Physical Chemistry, Oxford Press, 2006.
 Day, M. C. and Selbin, J. Theoretical Inorganic Chemistry, ACS Publications 1962.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 10 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(1st Semester)
Course No.:CHEMISTRY-C-101-LAB
(Inorganic Chemistry – I)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 1225
Examination Time: 12 hours (spread over two days)

During examination, Two experiments(one from each of the Part I and Part II), to be assigned
to each student by drawing lots.

1. Part I: Titrimetric Analysis 047 marks

(i) Calibration and use of apparatus
(ii) Preparation of solutions of different Molarity/Normality of titrants

2. Part II: Oxidation-Reduction Titrimetry 2014 marks

(i) Estimation of Fe (II) and oxalic acid using standardized KMnO4 solution.
(ii) Estimation of Fe (II) with K2Cr2O7solution.

3. Viva – voce 032 marks

4. Regularity in maintenance of Lab Notebook 03 2 marks

5. Attendance 03 5 marks

Reference Books:
 Vogel, A. I., A Textbook of Quantitative Inorganic Analysis, ELBS.
 Nad, A.K., Mahapatra, B., Ghoshal, A., An Advanced Course in Practical Chemistry,
New Central Book Agency (P) Ltd., Kolkata, India.
 Das, Subhas C, Advanced Practical Chemistry for 3-Year Honours Course.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 11 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(1st Semester)
Course No.:CHEMISTRY-C-102
(Physical Chemistry – I)
States of Matter & Ionic Equilibrium
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Objective of this course is to emphasize on different states of matter and their mathematical
treatment.

Unit 1: Gaseous State I

Kinetic molecular model of a gas: postulates and derivation of the kinetic gas equation;
collision frequency; collision diameter; mean free path and viscosity of gases, including their
temperature and pressure dependence, relation between mean free path and coefficient of
viscosity; variation of viscosity with temperature and pressure.
Maxwell distribution and its use in evaluating molecular velocities (average, root mean
square and most probable) and average kinetic energy, law of equipartitions of energy and
degrees of freedom.

Unit 2: Gaseous State II

Behaviour of real gases: Deviations from ideal gas behaviour, compressibility factor, Z, and
its variation with pressure for different gases. Causes of deviation from ideal behaviour. van
der Waals equation of state, its derivation and application in explaining real gas behaviour,
mention of other equations of state (Berthelot, Dietrici); virial equation of state. Isotherms of
real gases and their comparison with van der Waals isotherms, continuity of states, critical
state, relation between critical constants and van der Waals constants, law of corresponding
states.

Unit 3: Liquid State

Qualitative treatment of the structure of the liquid state; Radial distribution function; physical
properties of liquids; vapour pressure, surface tension and coefficient of viscosity, and their
determination. Effect of addition of various solutes on surface tension and viscosity.
Explanation of cleansing action of detergents. Temperature variation of viscosity of liquids
and comparison with that of gases.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 12 of 99

Unit 4: Solid State
Nature of the solid state, law of constancy of interfacial angles, law of rational indices, Miller
indices, elementary ideas of symmetry, symmetry elements and symmetry operations,
qualitative idea of point groups, seven crystal systems and fourteen Bravais lattices; X-ray
diffraction, Bragg’s law. Defects in crystals. Glasses and liquid crystals.

Unit 5: Ionic Equilibria

Strong, moderate and weak electrolytes, degree of ionization, factors affecting degree of
ionization, ionization constant and ionic product of water. Ionization of weak acids and bases,
pH scale, common ion effect; dissociation constants of mono-, di-and triprotic acids.
Salt hydrolysis-calculation of hydrolysis constant, degree of hydrolysis and pH for different
salts. Buffer solutions; derivation of Henderson equation and its applications; buffer capacity,
buffer range, buffer action and applications of buffers in analytical chemistry and
biochemical processes in the human body.
Solubility and solubility product of sparingly soluble salts – applications of solubility product
principle. Qualitative treatment of acid – base titration curves (calculation of pH at various
stages). Theory of acid–base indicators; selection of indicators and their limitations.

Reference Books:
 Atkins, P. W. & Paula, J. de Atkin’s Physical Chemistry Ed., Oxford University Press 13
(2006).
 Ball, D. W. Physical Chemistry Thomson Press, India (2007).
 Castellan, G. W. Physical Chemistry 4th Ed. Narosa (2004).
 Mortimer, R. G. Physical Chemistry 3 rd Ed. Elsevier: NOIDA, UP (2009).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 13 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(1st Semester)
Course No.:CHEMISTRY-C-102-LAB
(Physical Chemistry – I)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 1225
Examination Time: 12 hours (spread over two days)

During examination, Two experiments (one from each of the Part I and Part II), to be
assigned to each student by drawing lots.

1. Part I 16 10 marks

a) Determination of transition temperature of the given substance by thermometric method

(e.g., MgSO4/MnCl2/Na2SO4.10H2O).
b) To determine the surface tension of glycerol/acetic acid/aniline solutions at different
Concentrations and construction of graph.

2. Part II 11 marks
a) Preparation of Sodium acetate-acetic acid buffer solutions of different pH
b) Preparation of Ammonium chloride-ammonium hydroxide buffer solutions of different
pH
c) pH metric titration of strong acid/strong base,
d) pH metric titration of weak acid/strong base.

3. Viva – voce 2 marks

4. Regularity in maintenance of Lab Notebook 2 marks

5. Attendance 5 marks
Reference Books:
 Khosla, B. D.; Garg, V. C. & Gulati, A. Senior Practical Physical Chemistry, R. Chand &
Co.: New Delhi (2011).
 Halpern, A. M. & McBane, G. C. Experimental Physical Chemistry 3rd Ed.; W. H.
Freeman & Co.: New York (2003).
 Nad, A.K., Mahapatra, B., Ghoshal, A., An Advanced Course in Practical Chemistry,
New Central Book Agency (P) Ltd., Kolkata, India.
 Das, Subhas C., Advanced Practical Chemistry for 3-Year Honours Course.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 14 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(2nd Semester)
Course No.:CHEMISTRY-C-201
(Organic Chemistry – I)
Hydrocarbons and Stereochemistry
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Objective of this course is to impart knowledge on basic organic chemistry, hydrocarbon,

stereochemistry and conformational analysis

Unit 1: Basics of Organic Chemistry

Organic Compounds: Classification, and Nomenclature, Hybridization, Shapes of molecules,
Influence of hybridization on bond properties.

Electronic Displacements: Inductive, electromeric, resonance and mesomeric effects,

hyperconjugation and their applications; Dipole moment; Organic acids and bases; their
relative strength. Homolytic and Heterolytic fission with suitable examples. Curly arrow
rules, formal charges; Electrophiles and Nucleophiles; Nucleophlicity and basicity; Types,
shape and their relative stability of Carbocations, Carbanions, Free radicals and Carbenes.
Introduction to types of organic reactions and their mechanism: Addition, Elimination and
Substitution reactions.

Unit 2: Chemistry of Aliphatic Hydrocarbons

Formation of alkanes, Wurtz Reaction, Wurtz-Fittig Reactions, Free radical substitutions:
Halogenation -relative reactivity and selectivity.

Formation of alkenes and alkynes by elimination reactions, Mechanism of E1, E2, E1cb
reactions. Saytzeff and Hofmann eliminations.
Electrophilic additions their mechanisms (Markownikoff / Anti Markownikoff addition),
ozonolysis, reduction (catalytic and chemical). 1, 2-and 1, 4-addition reactions in conjugated
dienes and, Diels-Alder reaction; Allylic and benzylic bromination and mechanism, e.g.
propene, 1-butene, toluene, ethyl Benzene.

Acidity, Electrophilic and Nucleophilic additions. Hydration to form carbonyl compounds,

Alkylation of terminal alkynes.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 15 of 99

Unit 3: Aromatic and Polynuclear Hydrocarbons
Aromaticity: Hückel’s rule, aromatic character of arenes, cyclic carbocations/carbanions and
heterocyclic compounds with suitable examples. Electrophilic aromatic substitution:
halogenation, nitration, sulphonation and Friedel-Craft’s alkylation/acylation with their
mechanism. Directing effects of the groups.
Reactions of naphthalene phenanthrene and anthracene Structure, Preparation and structure
elucidation and important derivatives of naphthalene and anthracene; Polynuclear
hydrocarbons.

Unit 4: Stereochemistry
Fischer Projection, Newmann and Sawhorse Projection formulae and their inter-conversions;
Geometrical isomerism: cis–trans and, syn-anti isomerism E/Z notations with C.I.P rules.

Optical Isomerism: Optical Activity, Specific Rotation, Chirality/Asymmetry, Enantiomers,

molecules with two or more chiral-centres, diastereoisomers, meso structures, racemic
mixture and resolution. Relative and absolute configuration: D/L and R/S designations.

Unit 5: Cycloalkanes and Conformational Analysis

Types of cycloalkanes and their relative stability, Baeyer strain theory, Conformation
analysis of alkanes: Relative stability: Energy diagrams of cyclohexane, monosubstituted,
1,2-, 1,3-, 1,4-Disubstitutedcyclohexane: Chair, Boat and Twist boat forms; Relative stability
with energy diagrams, Strain-less ring theory.

Reference Books:
 Morrison, R. N. & Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd.
(Pearson Education).
 Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt. Ltd. (Pearson
Education).
 Finar, I. L. Organic Chemistry (Volume 2: Stereochemistry and the Chemistry of Natural
Products), Dorling Kindersley (India) Pvt. Ltd. (Pearson Education).
 Eliel, E. L. & Wilen, S. H. Stereochemistry of Organic Compounds; Wiley: London, 1994.
 Kalsi, P. S. Stereochemistry Conformation and Mechanism; New Age International, 2005.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 16 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(2nd Semester)
Course No.:CHEMISTRY-C-201-LAB
(Organic Chemistry – I)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 12 hours (spread over two days)
During examination, Two experiments (one from each of the Part I and Part II), to be
assigned to each student by drawing lots.
1. Part I: Purification: 08 10 marks
(a) Phthalic acid / Benzoic acid from hot water (using fluted filter paper and stem-
less funnel)
(b) Acetanilide from boiling water
(c) Naphthalene/ m-Dinitrobenzene from ethanol
(d) Naphthalene/ camphor/phthalic acid (by sublimation)
2. Part II: Chromatographic separation 16 11 marks
(a) 2,4-Dinitrophenyl hydrazones of any two carbonyl compounds (e.g.,
benzophenone and benzyl; p-nitrobenzaldehyde and benzaldehyde) from their
mixture and determination of Rf values (By Thin layer chromatography)
(b) Paper chromatographic separation and determination of Rf values of mixture of
any three amino acids from their mixture (alanine, glycine and leucine or any
other set). Spray reagent: Ninhydrin.

3. Viva – voce 2 marks

4. Regularity in maintenance of Lab Notebook 2 marks

5. Attendance 5 marks

Reference Books:
 Vogel, A. I., A Textbook of Qualitative Organic Analysis, ELBS.
 Nad, A.K., Mahapatra, B., Ghoshal, A., An Advanced Course in Practical Chemistry,
New Central Book Agency (P) Ltd., Kolkata, India.
 Furniss, B. S.; Hannaford, A. J.; Smith, P. W. G.; Tatchell, A. R., Practical Organic
Chemistry, 5 th Ed., Pearson (2012)
 Mann, F. G. & Saunders, B. C., Practical Organic Chemistry, Pearson Education (2009)
 Das, Subhas C., Advanced Practical Chemistry for 3-Year Honours Course.
Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 17 of 99
 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(2nd Semester)
Course No.:CHEMISTRY-C-202
(Physical Chemistry – II)
Chemical Thermodynamics and its Applications
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Objective of this course is to provide insight on Chemical Thermodynamics, their

mathematical expressions and Applications

Unit 1: Chemical Thermodynamics I

Intensive and extensive variables; state and path functions; isolated, closed and open systems;
zeroth law of thermodynamics.
First law: Concept of heat (q), work (w), internal energy (U), and statement of first law;
enthalpy (H), relation between heat capacities, calculations of q, w, U and H for reversible,
irreversible and free expansion of gases (ideal and van der Waals) under isothermal and
adiabatic conditions.
Thermochemistry: Heats of reactions: standard states; enthalpy of formation of molecules and
ions and enthalpy of combustion and its applications; calculation of bond energy, bond
dissociation energy and resonance energy from thermochemical data, effect of temperature
(Kirchhoff’s equations) and pressure on enthalpy of reactions. Adiabatic flame temperature,
explosion temperature.

Unit 2: Chemical Thermodynamics II

Second Law: Concept of entropy; thermodynamic scale of temperature, statement of the
second law of thermodynamics; molecular and statistical interpretation of entropy.
Calculation of entropy change for reversible and irreversible processes.
Third Law: Statement of third law, concept of residual entropy, calculation of absolute
entropy of molecules.
Free Energy Functions: Gibbs and Helmholtz energy; variation of S, G, A with T, V, P; Free
energy change and spontaneity. Relation between Joule-Thomson coefficient and other
thermodynamic parameters; inversion temperature; Gibbs-Helmholtz equation; Maxwell
relations; thermodynamic equation of state.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 18 of 99

Unit 3: Systems of Variable Composition
Partial molar quantities, dependence of thermodynamic parameters on composition; Gibbs-
Duhem equation, chemical potential of ideal mixtures, change in thermodynamic functions in
mixing of ideal gases.

Unit 4: Chemical Equilibrium

Criteria of thermodynamic equilibrium, degree of advancement of reaction, chemical
equilibria in ideal gases, concept of fugacity. Thermodynamic derivation of relation between
Gibbs free energy of reaction and reaction quotient. Coupling of exoergic and endoergic
reactions. Equilibrium constants and their quantitative dependence on temperature, pressure
and concentration. Free energy of mixing and spontaneity; thermodynamic derivation of
relations between the various equilibrium constants Kp, Kc and Kx. Le Chatelier’s Principle
(quantitative treatment); equilibrium between ideal gases and a pure condensed phase.

Unit 5: Solutions and Colligative Properties

Dilute solutions; lowering of vapour pressure, Raoult’s and Henry’s Laws and their
applications. Excess thermodynamic functions.
Thermodynamic derivation using chemical potential to derive relations between the four
colligative properties [(i) relative lowering of vapour pressure, (ii) elevation of boiling point,
(iii) Depression of freezing point, (iv) osmotic pressure] and amount of solute. Applications
in calculating molar masses of normal, dissociated and associated solutes in solution.

Reference Books:
• Peter, A. & Paula, J. de. Physical Chemistry 9th Ed., OUP (2011).
• Castellan, G. W. Physical Chemistry 4th Ed., Narosa (2004).
• Engel, T. & Reid, P. Physical Chemistry 3 rd Ed., Prentice-Hall (2012).
• McQuarrie, D. A. & Simon, J. D. Molecular Thermodynamics, Viva Books Pvt. Ltd.: New
Delhi (2004).
• Assael, M. J.; Goodwin, A. R. H.; Stamatoudis, M.; Wakeham, W. A. & Will, S.
Commonly Asked Questions in Thermodynamics, CRC Press: NY (2011).
• Levine, I. N. Physical Chemistry 6 th Ed., Tata Mc Graw Hill (2010).
• Metz, C. R. 2000 Solved Problems in Chemistry, Schaum Series (2006)

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 19 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(2nd Semester)
Course No.:CHEMISTRY-C-202-LAB
(Physical Chemistry – II)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 12 hours (spread over two days)

During examination, two experiments to be assigned to each student by drawing lots

1. Physical Experiments: 10.5x2=21 marks

i. To determine the viscosity of glycerol/acetic acid solutions at different concentrations

and construction of the graph.

ii. To determine the solubility of benzoic acid at different temperatures and to determine
pH of the dissolution process.

iii. To determine the refractive index of a given liquid by Abbe refractometer and to find
the specific and molar refraction.

iv. To determine the molecular mass by transition point method

(Solvent: Naphthalene /m-dinitrobenzene and Solute: Glucose/Urea)

2. Viva – voce 2 marks

3. Regularity in maintenance of Lab Notebook 2 marks

4. Attendance 5 marks

Reference Books:
• Khosla, B. D.; Garg, V. C. & Gulati, A., Senior Practical Physical Chemistry, R. Chand &
Co.: New Delhi (2011).
• Athawale, V. D. & Mathur, P. Experimental Physical Chemistry, New Age International:
New Delhi (2001).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 20 of 99

 CBCS: B. Sc. HONOURS with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(3rd Semester)
Course No.:CHEMISTRY-C-301
(Inorganic Chemistry – II)
s-, p- block Elements and Metallurgy

Contact Hours: 60; Credits: 04

Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Objective of this course is to provide insight on the chemistry of s-, p- block Elements, Noble
gases,inorganic polymers and Metallurgy

Unit 1: Chemistry of s- and p- Block Elements

Inert pair effect, Relative stability of different oxidation states, diagonal relationship and
anomalous behaviour of first member of each group. Allotropy and catenation. Complex
formation tendency of s- and p- block elements.
Hydrides and their classification ionic, covalent and interstitial.
Study of the following compounds with emphasis on structure, bonding, preparation,
properties and uses.
Boric acid and borates, boron nitrides, borohydrides (diborane) carboranes and graphitic
compounds, silanes, Oxides and oxoacids of nitrogen, Phosphorus and chlorine. Peroxo acids
of sulphur, interhalogen compounds, polyhalide ions, pseudohalogens and basic properties of
halogens.

Unit 2: Noble Gases

Occurrence and uses, rationalization of inertness of noble gases, Clathrates; preparation and
properties of XeF2, XeF4 and XeF6; Nature of bonding in noble gas compounds (Valence
bond treatment and MO treatment for XeF2). Molecular shapes of noble gas compounds
(VSEPR theory).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 21 of 99

Unit 3: Acids and Bases

Brönsted-Lowry concept of acid-base reactions, solvated proton, relative strength of acids,

types of acid-base reactions, levelling solvents, Lewis acid-base concept, Classification of
Lewis acids, Hard and Soft Acids and Bases (HSAB), Application of HSAB principle.

Unit 4: Inorganic Polymers

Types of inorganic polymers, comparison with organic polymers, synthesis, structural aspects
and applications of silicones and siloxanes. borazines, silicates.

Unit 5: General Principles of Metallurgy

Chief modes of occurrence of metals based on standard electrode potentials. Ellingham

diagrams for reduction of metal oxides using carbon and carbon monoxide as reducing agent.
Electrolytic Reduction, Hydrometallurgy. Methods of purification of metals: Electrolytic
processes and Mond’s process, Zone refining.

Reference Books:
 Lee, J.D. Concise Inorganic Chemistry, ELBS, 1991.
 Douglas, B.E; Mc Daniel, D.H. & Alexander, J.J., Concepts & Models of Inorganic
Chemistry 3 rd Ed., John Wiley Sons, N.Y. 1994.
 Greenwood, N. N. & Earnshaw, Chemistry of the Elements, Butterworth Heinemann.
1997.
 Cotton, F. A. & Wilkinson, G., Advanced Inorganic Chemistry, Wiley, VCH, 1999.
 Miessler, G. L. & Donald, A. Tarr., Inorganic Chemistry 4th Ed., Pearson, 2010.
 Shriver & Atkins, Inorganic Chemistry 5th Ed.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 22 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(3rd Semester)
Course No.:CHEMISTRY-C-301-LAB
(Inorganic Chemistry – II)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 12 hours (spread over two days)

During examination, two experiments (one from each of the Part I and Part II), to be assigned
to each student by drawing lots.

1.Part I: Iodo- / Iodimetric Titrations 14 marks

(i) Estimation of Cu (II) and K2Cr2O7 using sodium thiosulphate solution
(Iodimetrically).
(ii) Estimation of (i) arsenite and (ii) antimony iodimetrically
(iii) Estimation of available chlorine in bleaching powder iodometrically.

2.Part II: Inorganic preparations 7 marks

(i) Cuprous Chloride, Cu2Cl2
(ii) Preparation of Manganese (III) phosphate, MnPO4.H2O
(iii) Preparation of Aluminium potassium sulphate KAl(SO4)2.12H2O
(Potash alum) or Chrome alum.
(iv) Preparation of Chrome alum.

3. Viva – voce 2 marks

4. Regularity in maintenance of Lab Notebook 2 marks

5. Attendance 5 marks

Reference Books:
• Vogel, A. I., A Textbook of Quantitative Inorganic Analysis, ELBS (1978).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 23 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(3rd Semester)
Course No.:CHEMISTRY-C-302
(Organic Chemistry – II)
Halogen and Oxygen Containing Functional Groups
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)
Objective of this course is to provide insight on the synthesis and properties of organic
compounds containing Halogen and Oxygen Containing Functional Groups

Unit 1: Chemistry of Halogenated Hydrocarbons

Alkyl halides: Methods of preparation, nucleophilic substitution reactions – SN1, SN2 and SNi
mechanisms with stereochemical aspects and effect of solvent etc.; nucleophilic substitution
vs. elimination.
Aryl halides: Preparation, including preparation from diazonium salts. Nucleophilic aromatic
substitution; SNAr, Benzyne mechanism.
Relative reactivity of alkyl, allyl/benzyl, vinyl and aryl halides towards nucleophilic
substitution reactions.

Unit 2: Alcohols, Phenols, Ethers and Epoxides

Alcohols: preparation, properties and relative reactivity of 1°, 2°, 3° alcohols, Bouvaelt-Blanc
Reduction; Preparation and properties of glycols: Oxidation by periodic acid and lead
tetraacetate, Pinacol-Pinacolone rearrangement;
Phenols: Preparation & properties; Acidity and factors effecting it, Ring substitution
reactions, Reimer–Tiemann and Kolbe’s–Schmidt Reactions, Fries and Claisen
rearrangements with mechanism;
Ethers and Epoxides: Preparation and reactions with acids. Reactions of epoxides with
alcohols, ammonia derivatives and LiAlH4

Unit 3: Carbonyl Compounds

Structure, reactivity and preparation;
Nucleophilic additions, Nucleophilic addition-elimination reactions with ammonia
derivatives with mechanism; Mechanisms of Aldol and Benzoin condensation, Knoevenagel
condensation, Claisan-Schmidt, Perkin, Cannizzaro and Wittig reaction, Beckmann and
Benzil-Benzilic acid rearrangements, haloform reaction and Baeyer Villiger oxidation, α-

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 24 of 99

substitution reactions, oxidations and reductions (Clemmensen, Wolff-Kishner, LiAlH4,
MPV). Addition reactions of unsaturated carbonyl compounds: Michael addition.

Unit 4: Carboxylic Acids and their Derivatives

Preparation, physical properties and reactions of monocarboxylic acids: Typical reactions of
dicarboxylic acids, hydroxy acids and unsaturated acids: succinic/phthalic, lactic, malic,
tartaric, citric, maleic and fumaric acids;
Preparation and reactions of acid chlorides, anhydrides, esters and amides; Comparative
study of nucleophilic substitution at acyl group -Mechanism of acidic and alkaline hydrolysis
of esters, Claisen condensation, Dieckmann and Reformatsky reactions, Hofmann-
bromamide degradation and Curtius rearrangement.

Unit 5: Other Organic compounds

Preparation and reactions of thiols, thioethers and sulphonic acids.
Organometallic compounds of Mg and Li – Use in synthesis of organic compounds.
Active methylene compounds: Keto-enol tautomerism. Preparation and synthetic applications
of diethyl malonate and ethyl acetoacetate.

Reference Books:
• Morrison, R. T. & Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd.
(Pearson Education).
• Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt. Ltd. (Pearson
Education).
• Graham Solomons, T. W. Organic Chemistry, John Wiley & Sons, Inc.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 25 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(3rd Semester)
Course No.:CHEMISTRY-C-302-LAB
(Organic Chemistry – II)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 12 hours (spread over two days)

During examination, two experiments (one from each of the Part I and Part II), to be assigned
to each student by drawing lots.

1. Part I: Tests for functional groups 12 14marks

Alcohols, phenols, carbonyl and carboxylic acid group.

2. Organic preparations: 12 7 marks

i. Acetylation of one of the following compounds: amines (aniline, o-, m-, p-
toluidines and o-, m-, p-anisidine) and phenols (β-naphthol, vanillin) by
conventional/green approach method.
ii. Benzoylation of one of the following amines (aniline, o-, m-, p- toluidines and o-,
m-, p-anisidine) and one of the following phenols (β-naphthol, resorcinol, p-
cresol) by Schotten-Baumann reaction.
iii. Nitration of Acetanilide/nitrobenzene by conventional method
iv. Nitration ofSalicylic acid (preferably by green approach using ceric ammonium
nitrate).
The above derivatives should be prepared using 0.5-1 g of the organic compound. The solid
samples must be collected and may be used for recrystallization, melting point.
3. Viva – voce 2 marks
4. Regularity in maintenance of Lab Notebook 2 marks
5. Attendance 5 marks
Reference Books:
• Mann, F. G. & Saunders, B. C. Practical Organic Chemistry, Pearson Education (2009)
• Furniss, B. S.; Hannaford, A. J.; Smith, P.W.G.; Tatchell, A. R. Practical Organic
Chemistry, 5 th Ed., Pearson (2012).
• Ahluwalia, V. K. & Aggarwal, R. Comprehensive Practical Organic Chemistry:
Preparation and Quantitative Analysis, University Press (2000).
• Ahluwalia, V. K. & Dhingra, S. Comprehensive Practical Organic Chemistry: Qualitative
Analysis, University Press (2000).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 26 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(3rd Semester)
Course No.:CHEMISTRY-C-303
(Physical Chemistry – III)
Phase Equilibria and Chemical Kinetics
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Objective of this course is to emphasise in details on Phase Equilibria, Chemical Kinetics,

catalysis and Surface chemistry.

Unit 1: Phase Equilibria I

Concept of phases, components and degrees of freedom, derivation of Gibbs Phase Rule for
nonreactive and reactive systems; Clausius-Clapeyron equation and its applications to solid-
liquid, liquid-vapour and solid-vapour equilibria, phase diagram for one component systems,
with applications.
Phase diagrams for systems of solid-liquid equilibria involving eutectic, congruent and
incongruent melting points, solid solutions. Three component systems, water-chloroform-
acetic acid system, triangular plots.

Unit 2: Phase Equilibria II

Binary solutions: Gibbs-Duhem-Margules equation, its derivation and applications to
fractional distillation of binary miscible liquids (ideal and nonideal), azeotropes, lever rule,
partial miscibility of liquids, CST, miscible pairs, steam distillation. Nernst distribution law:
its derivation and applications.

Unit 3: Chemical Kinetics

Order and molecularity of a reaction, rate laws in terms of the advancement of a reaction,
differential and integrated form of rate expressions up to second order reactions, experimental
methods of the determination of rate laws, kinetics of complex reactions (integrated rate
expressions up to first order only): (i) Opposing reactions (ii) parallel reactions and (iii)
consecutive reactions and their differential rate equations (steady-state approximation in
reaction mechanisms) (iv) chain reactions.
Temperature dependence of reaction rates; Arrhenius equation; activation energy. Collision
theory of reaction rates, Lindemann mechanism, qualitative treatment of the theory of
absolute reaction rates.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 27 of 99

Unit 4: Catalysis
Types of catalyst, specificity and selectivity, mechanisms of catalyzed reactions at solid
surfaces; effect of particle size and efficiency of nanoparticles as catalysts. Enzyme catalysis,
Michaelis-Menten mechanism, acid-base catalysis.

Unit 5: Surface chemistry

Physical adsorption, chemisorption, adsorption isotherms, nature of adsorbed state.

Reference Books:
• Peter Atkins & Julio De Paula, Physical Chemistry 9th Ed., Oxford University Press
(2010).
• Castellan, G. W. Physical Chemistry, 4th Ed., Narosa (2004).
• McQuarrie, D. A. & Simon, J. D., Molecular Thermodynamics, Viva Books Pvt. Ltd.:
New Delhi (2004).
• Engel, T. & Reid, P. Physical Chemistry 3 rd Ed., Prentice-Hall (2012).
• Assael, M. J.; Goodwin, A. R. H.; Stamatoudis, M.; Wakeham, W. A. & Will, S.
Commonly Asked Questions in Thermodynamics. CRC Press: NY (2011).
• Zundhal, S.S. Chemistry concepts and applications Cengage India (2011).
• Ball, D. W. Physical Chemistry Cengage India (2012).
• Mortimer, R. G. Physical Chemistry 3 rd Ed., Elsevier: NOIDA, UP (2009).
• Levine, I. N. Physical Chemistry 6 th Ed., Tata McGraw-Hill (2011).
• Metz, C. R. Physical Chemistry 2nd Ed., Tata McGraw-Hill (2009).
• Laidler, K. J., Chemical Kinetics 3 rd Ed., Pearson Education India (2008).
• Kapoor, K. L., A Textbook of Physical Chemistry – Vol. 1 – 6, 2nd Ed., Laxmi
Publications-New Delhi (2011).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 28 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(3rd Semester)
Course No.:CHEMISTRY-C-303-LAB
(Physical Chemistry – III)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 12 hours (spread over two days)

During examination, two experiments (one from each of the Part I and Part II), to be assigned
to each student by drawing lots.

1. Part I: Study of the equilibrium of the following reactions by the distribution

method: 7 marks
(i) ( ) + → ( )
(ii) ( ) + → ( )

2. Part II: Study the kinetics of the following reactions(any one) 14 marks
a) Initial rate method: Iodide-persulphate reaction
b)Integrated rate method: Acid hydrolysis of methyl acetate with hydrochloric acid.
c) Integrated rate method: Saponification of ethyl acetate.
d)Comparison the strengths of HCl and H2SO4 by studying kinetics of hydrolysis of
methyl acetate.
e) Adsorption: Verification of the Freundlich isotherms for adsorption of oxalic acid /
acetic acid on activated charcoal.

3. Viva – voce 2 marks

4. Regularity in maintenance of Lab Notebook 2 marks

5. Attendance 5 marks
Reference Books:
• Khosla, B. D.; Garg, V. C. & Gulati, A. Senior Practical Physical Chemistry, R. Chand &
Co.: New Delhi (2011).
• Garland, C. W.; Nibler, J. W. & Shoemaker, D. P. Experiments in Physical Chemistry 8 th
Ed.; McGraw-Hill: New York (2003).
• Halpern, A. M. & McBane, G. C. Experimental Physical Chemistry 3 rd Ed.; W. H.
Freeman & Co.: New York (2003).
• Jadav, J. B., Advance Physical Practical Chemistry, Goel Publishing House, New Delhi
(1981).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 29 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(4th Semester)
Course No.:CHEMISTRY-C-401
(Inorganic Chemistry – III)
Coordination Chemistry and its Applications
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Objective of this course is to provide in-depth discussion on Coordination Chemistry and its
Applications, extended to Biological systems

Unit 1: Coordination Chemistry I

Werner’s theory, valence bond theory (inner and outer orbital complexes), electroneutrality
principle and back bonding. Crystal field theory, measurement of 10 Dq (Δo), CFSE in weak
and strong fields, pairing energies, factors affecting the magnitude of 10 Dq (Δo, Δt).
Octahedral vs. tetrahedral coordination, tetragonal distortions from octahedral geometry
Jahn-Teller theorem, square planar geometry. Qualitative aspect of Ligand field and MO
Theory.

Unit 2: Coordination Chemistry II

IUPAC (2005) nomenclature of coordination compounds, isomerism in coordination
compounds. Stereochemistry of complexes with 4 and 6 coordination numbers. Chelate
effect, polynuclear complexes, Labile and inert complexes.

Unit 3: Transition Elements

General group trends with special reference to electronic configuration, colour, variable
valency, magnetic and catalytic properties and ability to form complexes. Stability of various
oxidation states and e.m.f. (Latimer & Ebsworth diagrams). Difference between the first,
second and third transition series. Chemistry of Cr and Mn in various oxidation states
(excluding their metallurgy).

Unit 4: Lanthanoids and Actinoids

Electronic configuration, oxidation states, colour, spectral and magnetic properties,
lanthanide contraction, separation of lanthanides (ion-exchange method only).

Unit 5: Bioinorganic Chemistry

Metal ions present in biological systems, classification of elements according to their action
in biological system.Excess and deficiency of some trace metals.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 30 of 99

Toxicity of metal ions (Hg, Pb, Cd and As), reasons for toxicity, use of chelating agents in
medicine.

Reference Books:
• Purcell, K. F & Kotz, J. C. Inorganic Chemistry W. B. Saunders Co, 1977.
• Huheey, J. E., Inorganic Chemistry, Prentice Hall, 1993.
• Lippard, S. J. & Berg, J. M. Principles of Bioinorganic Chemistry Panima Publishing
Company 1994.
• Cotton, F. A. & Wilkinson, G, Advanced Inorganic Chemistry. Wiley-VCH, 1999
• Basolo, F, and Pearson, R. C., Mechanisms of Inorganic Chemistry, John Wiley & Sons,
NY, 1967.
• Greenwood, N. N. & Earnshaw A., Chemistry of the Elements, Butterworth Heinemann,
1997.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 31 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(4th Semester)
Course No.:CHEMISTRY-C-401-LAB
(Inorganic Chemistry – III)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 12 hours (spread over two days)

During examination, two experiments (one from each of the Part I and Part II), to be assigned
to each student by drawing lots

1. Part I: Gravimetric Analysis: 14 marks

i. Estimation of nickel (II) using Dimethylglyoxime (DMG).
ii. Estimation of copper as CuSCN
iii. Estimation of iron as Fe2O3 by precipitating iron as Fe(OH)3.

2. Part II: Inorganic Preparations: 7 marks

i. Tetraamminecopper (II) sulphate, [Cu(NH3)4]SO4.H2O
ii. Sodium trioxalatochromate (III)
iii. Tetraamminecarbonatocobalt (III) ion
iv. Potassium tris(oxalate)ferrate (III)

3. Viva – voce 2 marks

4. Regularity in maintenance of Lab Notebook 2 marks

5. Attendance 5 marks

Reference Books:
• Vogel, A. I., A Textbook of Quantitative Inorganic Analysis, ELBS. 1978

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 32 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(4th Semester)
Course No.:CHEMISTRY-C-402
(Organic Chemistry – III)
Heterocyclic Chemistry
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Objective of this course is to provide knowledge on the preparation and properties of

different classes of heterocyclic organic compounds. Emphases is given to heterocyclic
compounds of both synthetic and natural origin.

Unit 1: Nitrogen Containing Functional Groups

Preparation and important reactions of nitro and compounds, nitriles and isonitriles Amines:
Effect of substituent and solvent on basicity; Preparation and properties: Gabriel phthalimide
synthesis, Carbylamine reaction, Mannich reaction, Hoffmann’s exhaustive methylation,
Hofmann-elimination reaction; Distinction between 1°, 2° and 3°amines with Hinsberg
reagent and nitrous acid. Diazonium Salts: Preparation and their synthetic applications.

Unit 2: Heterocyclic Compounds - I

Classification and nomenclature, Structure, aromaticity in 5-numbered and 6-membered rings
containing one heteroatom; Synthesis, reactions and mechanism of substitution reactions of:
Furan, Pyrrole (Paal-Knorr synthesis, Knorr pyrrole synthesis, Hantzsch synthesis),
Thiophene, Pyridine (Hantzsch synthesis).

Unit 3: Heterocyclic Compounds - II

Pyrimidine, Structure elucidation of indole, Fischer indole synthesis and Madelung
synthesis), Structure elucidation of quinoline and isoquinoline, Skraup synthesis,
Friedlander’s synthesis, Knorr quinoline synthesis, DoebnerMiller synthesis, Bischler-
Napieralski reaction, Pictet-Spengler reaction, Pomeranz-Fritsch reaction. Derivatives of
furan: Furfural and furoic acid.

Unit 4: Alkaloids
Natural occurrence, General structural features, Isolation and their physiological action.
Hoffmann’s exhaustive methylation, Emde’s modification, Structure elucidation and
synthesis of Hygrine and Nicotine. Medicinal importance of Nicotine, Hygrine, Quinine,
Morphine, Cocaine, and Reserpine.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 33 of 99

Unit 5: Terpenes
Occurrence, classification, isoprene rule; Elucidation of stucture and synthesis of Citral,
Neral and -terpineol.

Reference Books:
• Morrison, R. T. & Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd.
(Pearson Education).
• Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt. Ltd. (Pearson
Education).
• Finar, I. L. Organic Chemistry (Volume 2: Stereochemistry and the Chemistry of Natural
Products), Dorling Kindersley (India) Pvt. Ltd. (Pearson Education).
• Acheson, R.M. Introduction to the Chemistry of Heterocyclic compounds, John Welly &
Sons (1976).
• Graham Solomons, T.W. Organic Chemistry, John Wiley & Sons, Inc.
• Kalsi, P. S. Textbook of Organic Chemistry 1 st Ed., New Age International (P) Ltd. Pub.
• Clayden, J.; Greeves, N.; Warren, S.; Wothers, P.; Organic Chemistry, Oxford University
Press.
• Singh, J.; Ali, S. M. & Singh, J. Natural Product Chemistry, Prajati Parakashan (2010).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 34 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(4th Semester)
Course No.:CHEMISTRY-C-401-LAB
(Inorganic Chemistry – III)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 12 hours (spread over two days)

During examination, one experiments to be assigned to each student by drawing lots

1. Qualitative Organic analysis 24 21 marks

Detection of elements (N, S and halogens) and functional groups, determination of melting
points and preparation of suitable derivatives to identify the given organic compounds
(Preferable by capillary method)

2. Viva – voce 2 marks

3. Regularity in maintenance of Lab Notebook 2 marks

4. Attendance 5 marks

Reference Books:
• Mann, F. G. & Saunders, B. C. Practical Organic Chemistry, Pearson Education (2009).
• Furniss, B. S.; Hannaford, A. J.; Smith, P. W. G.; Tatchell, A. R. Practical Organic
Chemistry, 5 th Ed., Pearson (2012).
• Ahluwalia, V. K. & Aggarwal, R. Comprehensive Practical Organic Chemistry:
Preparation and Quantitative Analysis, University Press (2000).
• Ahluwalia, V. K. & Dhingra, S. Comprehensive Practical Organic Chemistry: Qualitative
Analysis, University Press (2000).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 35 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(4th Semester)
Course No.:CHEMISTRY-C-403
(Physical Chemistry – IV)
Electrochemistry
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Objective of this course is to provide knowledge on Electrochemistry, various laws governing

electrochemical processes and their applications.

Unit 1: Conductance I
Arrhenius theory of electrolytic dissociation. Conductivity, equivalent and molar conductivity
and their variation with dilution for weak and strong electrolytes. Molar conductivity at
infinite dilution. Kohlrausch law of independent migration of ions. Debye-Hückel-Onsager
equation, Wien effect, Debye-Falkenhagen effect, Walden’s rules.
Unit 2: Conductance II
Ionic velocities, mobilities and their determinations, transference numbers and their relation
to ionic mobilities, determination of transference numbers using Hittorf and Moving
Boundary methods. Applications of conductance measurement: (i) degree of dissociation of
weak electrolytes, (ii) ionic product of water (iii) solubility and solubility product of
sparingly soluble salts, (iv) conductometric titrations, and (v) hydrolysis constants of salts.
Unit 3: Electrochemistry I
Quantitative aspects of Faraday’s laws of electrolysis, rules of oxidation/reduction of ions
based on half-cell potentials, applications of electrolysis in metallurgy and industry.
Chemical cells, reversible and irreversible cells with examples. Electromotive force of a cell
and its measurement, Nernst equation; Standard electrode (reduction) potential and its
application to different kinds of half-cells.
Unit 4: Electrochemistry II
Application of EMF measurements in determining (i) free energy, enthalpy and entropy of a
cell reaction, (ii) equilibrium constants, and (iii) pH valuesusing hydrogen/glass electrodes.
Concentration cells with and without transference, liquid junction potential; determination of
activity coefficients and transference numbers. Qualitative discussion of potentiometric
titrations (acid-base, redox, precipitation).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 36 of 99

Unit 5: Electrical & Magnetic Properties of Atoms and Molecules
Basic ideas of electrostatics, Electrostatics of dielectric media, Clausius-Mosotti equation,
Lorenz-Laurentz equation, Dipole moment and molecular polarizabilities and their
measurements. Diamagnetism, paramagnetism, magnetic susceptibility and its measurement.

Reference Books:
• Atkins, P. W & Paula, J. D. Physical Chemistry, 9th Ed., Oxford University Press (2011).
• Castellan, G. W. Physical Chemistry 4th Ed., Narosa (2004).
• Mortimer, R. G. Physical Chemistry 3 rd Ed., Elsevier: NOIDA, UP (2009).
• Barrow, G. M., Physical Chemistry 5 th Ed., Tata McGraw Hill: New Delhi (2006).
• Engel, T. & Reid, P. Physical Chemistry 3 rd Ed., Prentice-Hall (2012).
• Rogers, D. W. Concise Physical Chemistry Wiley (2010).
• Silbey, R. J.; Alberty, R. A. & Bawendi, M. G. Physical Chemistry 4th Ed., John Wiley &
Sons, Inc. (2005).
• Puri, B.R., Sharma, L.R., Pathania, M.S., Principles of Physical Chemistry, Vishal
Publishing Co., Punjab (India).
• Glasstone, Samuel, An Introduction To Electrochemistry,Affiliated East West Press
Private, Limited., Maurice Press.
• Raj, Gurdeep, Advanced Physical Chemistry, Krishna Prakashan Media (P) Ltd., New
Delhi (1978).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 37 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(4th Semester)
Course No.:CHEMISTRY-C-403-LAB
(Physical Chemistry – IV)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 12 hours (spread over two days)

During examination, two experiments to be assigned to each student by drawing lots.

1. Physical experiments:24 10.5x2=21marks

1. pH metric titration of HCl against standard NaOH
2. To determine the strength of the given acid conductometrically using standard
alkali solution.
3. Determination of equivalent conductances of a strong electrolyte at various
dilutions and verification of Onsagar equation.
4. Determination of equivalent conductance, degree of dissociation and dissociation
constant of a weak acid.
5. Conductometric titration of a mixture of strong and weak acid vs strong base.
6. pH metric titration of a mixture of strong and weak acid vs strong base.
7. Potentiometric titration of ferrous ammonium sulphate against standard K2Cr2O7/
KMnO4 and determination of redox potential of Fe(II)- Fe(III) system.
2. Viva – voce 2 marks
3. Regularity in maintenance of Lab Notebook 2 marks
4. Attendance 5 marks
Reference Books:
• Khosla, B. D.; Garg, V. C. & Gulati, A. Senior Practical Physical Chemistry, R. Chand &
Co.: New Delhi (2011).
• Garland, C. W.; Nibler, J. W. & Shoemaker, D. P. Experiments in Physical Chemistry 8 th
Ed.; McGraw-Hill: New York (2003).
• Halpern, A. M. & McBane, G. C. Experimental Physical Chemistry 3 rd Ed.; W. H.
Freeman & Co.: New York (2003).
• Jadav, J. B., Advance Physical Practical Chemistry, Goel Publishing House, New Delhi
(1981).
• Palit, S. R. and De, S.K., Practical Physical Chemistry Science Book Agency.
• Das, R.C. and Behra, B., Experimental Physical Chemistry, McGraw Hill.
Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 38 of 99
 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(5th Semester)
Course No.:CHEMISTRY-C-501
(Organic Chemistry – IV)
Biomolecules
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Objective of this course is to provide knowledge on the selected types ofnaturally occurring
organic compounds, their synthesis, physiological importance and pharmaceutical
applications

Unit 1: Nucleic Acids

Components of nucleic acids, Nucleosides and nucleotides;
Structure, synthesis and reactions of: Adenine, Guanine, Cytosine, Uracil and Thymine;
Structure of polynucleotides.
Unit 2: Amino Acids, Peptides and Proteins
Amino acids, Peptides and their classification.
-Amino Acids - Synthesis, ionic properties and reactions. Zwitterions, pKa values,
isoelectric point and electrophoresis;
Study of peptides: determination of their primary structures-end group analysis, methods of
peptide synthesis.
Unit 3: Enzymes
Introduction, classification and characteristics of enzymes. Salient features of active site of
enzymes.
Mechanism of enzyme action, factors affecting enzyme action, coenzymes and cofactors and
their role in biological reactions, specificity of enzyme action (including stereospecificity),
enzyme inhibitors and their importance.
Unit 4: Lipids
Introduction to oils and fats; common fatty acids present in oils and fats, Hydrogenation of
fats and oils, Saponification value, acid value, iodine number.
Unit 5: Pharmaceutical Compounds: Structure and Importance
Classification, structure and therapeutic uses of antipyretics: Paracetamol (with synthesis),
Analgesics: Ibuprofen (with synthesis), Antimalarials: Chloroquine (with synthesis). An

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 39 of 99

elementary treatment of Antibiotics and detailed study of chloramphenicol, Medicinal values
of curcumin (haldi), azadirachtin (neem), vitamin C and antacid (ranitidine).

Reference Books:
• Berg, J. M., Tymoczko, J. L. and Stryer, L. Biochemistry. 6 th Edition. W. H. Freeman and
Co (2006).
• Nelson, D. L., Cox, M. M. and Lehninger, A. L. Principles of Biochemistry. 4th Edition.
W. H. Freeman and Co (2009).
• Murray, R. K., Granner, D. K., Mayes, P. A. and Rodwell, V. W. Harper’s Illustrated
Biochemistry. XXVIII Edition. Lange Medical Books/ McGraw-Hill (2009).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 40 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(5th Semester)
Course No.:CHEMISTRY-C-501-LAB
(Organic Chemistry – IV)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 12 hours (spread over two days)

During examination, two experiments (one from each of the Part I and Part II), to be assigned
to each student by drawing lots.

1. Part I: Organic synthesis: 7 marks

(a) Acetylation of salicylic acid, aniline, and hydroquinone, benzoylation of aniline
and phenol.
(b) Aliphatic electrophilic substitution: preparation of iodoform from
acetone/ethanol.
(c) Aromatic electrophilic substitution: preparation of m-dinitrobenzene/preparation
of methyl orange.

2. Part II: Organic quantitative analysis: 14 marks

(i) Estimation of glucose/cholesterol/ urea/uric acid by colorimeteror by chemical
methods.
(ii) Determination of saponification equivalent of an ester

3. Viva – voce 2 marks

4. Regularity in maintenance of Lab Notebook 2 marks

5. Attendance 5 marks

Reference Books:
• Manual of Biochemistry Workshop, 2012, Department of Chemistry, University of Delhi.
• Arthur, I. V. Quantitative Organic Analysis, Pearson.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 41 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(5th Semester)
Course No.:CHEMISTRY-C-502
(Physical Chemistry – V)
Quantum Chemistry & Spectroscopy
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Objective of this course is to provide knowledge on Quantum Chemistry &Molecular

Spectroscopy and Photochemistry

Unit 1: Quantum Chemistry I

Postulates of quantum mechanics, quantum mechanical operators, Schrödinger equation and

its application to free particle and “particle-in-a-box”, quantization of energy levels, zero-
point energy and Heisenberg Uncertainty principle; wave functions, probability distribution
functions, Extension to two and three dimensional boxes, separation of variables, degeneracy.

Qualitative treatment of simple harmonic oscillator model of vibrational motion: Setting up

of Schrödinger equation and discussion of solution and wave functions. Vibrational energy of
diatomic molecules and zero-point energy.

Rigid rotator model of rotation of diatomic molecule. Schrödinger equation, transformation to

spherical polar coordinates. Separation of variables. Spherical harmonics. Discussion of
solution.

Unit 2: Quantum Chemistry II

Qualitative treatment of hydrogen atom and hydrogen-like ions: setting up of Schrödinger

equation in spherical polar coordinates, radial part, quantization of energy (only final energy
expression). Average and most probable distances of electron from nucleus.

Setting up of Schrödinger equation for many-electron atoms (He, Li). Need for
approximation methods. Statement of variation theorem and application to simple systems
(particle-in-a-box, harmonic oscillator, hydrogen atom).

Chemical bonding: Covalent bonding, valence bond and molecular orbital approaches,
LCAO-MO treatment of H2+. Bonding and antibonding orbitals. Qualitative extension to H2.

Comparison of LCAO-MO and VB treatments of H2 (only wave functions, detailed solution

not required) and their limitations. Qualitative description of LCAO-MO treatment of
homonuclear and heteronuclear diatomic molecules (HF, LiH).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 42 of 99

Unit 3: Molecular Spectroscopy I

Interaction of electromagnetic radiation with molecules and various types of spectra; Born-
Oppenheimer approximation.
Rotation spectroscopy: Selection rules, intensities of spectral lines, determination of bond
lengths of diatomic molecules.
Vibrational spectroscopy: Classical equation of vibration, computation of force constant,
amplitude of diatomic molecular vibrations, fundamental frequencies, concept of group
frequencies. Vibration-rotation spectroscopy: diatomic vibrating rotator, P, Q, R branches.

Unit 4: Molecular Spectroscopy II

Raman spectroscopy: Qualitative treatment of Rotational Raman effect; Stokes and anti-
Stokes lines; their intensity difference, rule of mutual exclusion.
Electronic spectroscopy: Franck-Condon principle, electronic transitions, singlet and triplet
states, fluorescence and phosphorescence.
Nuclear Magnetic Resonance (NMR) spectroscopy: Principles of NMR spectroscopy,
chemical shift and low resolution spectra, different scales, spin-spin coupling and high
resolution spectra, interpretation of PMR spectra of simple organic molecules.

Unit 5: Photochemistry

Characteristics of electromagnetic radiation, Lambert-Beer’s law and its limitations, physical

significance of absorption coefficients. Laws, of photochemistry, quantum yield, actinometry,
examples of low and high quantum yields, photosensitized reactions, quenching.
Chemiluminescence.

Reference Books: (C XIII)

• Banwell, C. N. & McCash, E. M. Fundamentals of Molecular Spectroscopy 4th Ed. Tata
McGraw-Hill: New Delhi (2006).
• Chandra, A. K. Introductory Quantum Chemistry Tata McGraw-Hill.
• House, J. E. Fundamentals of Quantum Chemistry 2 nd Ed. Elsevier: USA.
• Lowe, J. P. & Peterson, K. Quantum Chemistry, Academic Press (2005).
• Kakkar, R. Atomic & Molecular Spectroscopy, Cambridge University Press.
• Macqurre, D. A., Quantum Chemistry.
• Atkins, Peter W. and Friedman, Ronald S., Molecular Quantum Mechanics 5th Edition.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 43 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(5th Semester)
Course No.:CHEMISTRY-C-502-LAB
(Physical Chemistry – V)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 12 hours (spread over two days)

During examination, two experiments (one from each of the Part I and Part II), to be assigned
to each student by drawing lots.

1. Physical Experiments: 10.5x2=21 marks

I. Verification of Lambert-Beer’s law and determine the concentration of
CuSO4/KMnO4/K2Cr2O7 in a solution of unknown concentration
II. Determination of the concentrations of KMnO4 and K2Cr2O7 in a mixture.
III. Study of the kinetics of iodination of propanone in acidic medium.
IV. Determination of the amount of iron present in a sample using
1,10-phenathroline.
V. Determination of the dissociation constant of an indicator (phenolphthalein).
VI. Study of the kinetics of interaction of crystal violet/ phenolphthalein with sodium
hydroxide.

2. Viva – voce 2 marks

3. Regularity in maintenance of Lab Notebook 2 marks

4. Attendance 5 marks

Reference Books:
• Khosla, B. D.; Garg, V. C. & Gulati, A., Senior Practical Physical Chemistry, R. Chand &
Co.: New Delhi (2011).
• Garland, C. W.; Nibler, J. W. & Shoemaker, D. P. Experiments in Physical Chemistry 8 th
Ed.; McGraw-Hill: New York (2003).
• Halpern, A. M. & McBane, G. C. Experimental Physical Chemistry 3rd Ed.; W. H.
Freeman & Co.: New York (2003).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 44 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(6th Semester)
Course No.:CHEMISTRY-C-601
(Inorganic Chemistry – IV)
Organometallic Chemistry
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)
Objective of this course is to emphases on the basics knowledge on Organometallic
compounds, their chemistry, application in catalysis and inorganic reaction mechanisms

Unit 1: Organometallic Compounds - I

Definition and classification of organometallic compounds on the basis of bond type.
Concept of hapticity of organic ligands.
Metal carbonyls: 18 electron rule, electron count of mononuclear, polynuclear and substituted
metal carbonyls of 3d series.
Ferrocene: Structure and aromaticity. Comparison of aromaticity and reactivity with that of
benzene.

Unit 2: Organometallic Compounds - II

Metal Alkyls: Important structural features of methyl lithium (tetramer) and trialkyl
aluminium (dimer), concept of multicentre bonding in these compounds.
Role of triethylaluminium in polymerisation of ethene (Ziegler – Natta Catalyst). Species
present in ether solution of Grignard reagent and their structures.

Unit 3: Reaction Kinetics and Mechanism

Introduction to inorganic reaction mechanisms. Substitution reactions in square planar
complexes, Trans- effect, theories of trans effect, Mechanism of nucleophilic substitution in
square planar complexes, Thermodynamic and Kinetic stability, Ligand field effects and
reaction rates, Mechanism of substitution in octahedral complexes.

Unit 4: Catalysis by Organometallic Compounds

Study of the following industrial processes and their mechanism:
1. Alkene hydrogenation (Wilkinsons Catalyst)
2. Hydroformylation (Co salts)
3. Synthetic gasoline (Fischer Tropsch reaction)
4. Synthesis gas by metal carbonyl complexes
Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 45 of 99
Unit 5: Principles in Qualitative Analysis

Basic principles involved in analysis of cations and anions and solubility products, common
ion effect. Principles involved in separation of cations into groups and choice of group
reagents. Interfering anions (fluoride, borate, oxalate and phosphate) and need to remove
them after Group II.

Reference Books:
• Vogel, A. I. Qualitative Inorganic Analysis, Longman, 1972.
• Svehla, G. Vogel's Qualitative Inorganic Analysis, 7 th Ed., Prentice Hall.
• Cotton, F. A. G.; Wilkinson & Gaus, P. L. Basic Inorganic Chemistry 3 rd Ed.; Wiley India,
• Huheey, J. E.; Keiter, E. A. & Keiter, R. L. Inorganic Chemistry, Principles of Structure
and Reactivity 4 th Ed., Harper Collins 1993, Pearson, 2006.
• Sharpe, A. G. Inorganic Chemistry, 4 th Indian Reprint (Pearson Education) 2005
• Douglas, B. E.; McDaniel, D. H. & Alexander, J. J. Concepts and Models in Inorganic
Chemistry 3 rd Ed., John Wiley and Sons, NY, 1994.
• Greenwood, N. N. & Earnshaw, A. Chemistry of the Elements, Elsevier 2 nd Ed, 1997
(Ziegler Natta Catalyst and Equilibria in Grignard Solution).
• Lee, J. D. Concise Inorganic Chemistry 5 th Ed., John Wiley and sons 2008.
• Powell, P. Principles of Organometallic Chemistry, Chapman and Hall, 1988.
• Shriver, D. D. & P. Atkins, Inorganic Chemistry 2nd Ed., Oxford University Press, 1994.
• Basolo, F. & Person, R. Mechanisms of Inorganic Reactions: Study of Metal Complexes
in Solution 2 nd Ed., John Wiley & Sons Inc; NY.
• Purcell, K. F. & Kotz, J. C., Inorganic Chemistry, W. B. Saunders Co. 1977
• Miessler, G. L. & Donald, A. Tarr, Inorganic Chemistry 4 th Ed., Pearson, 2010.
• Collman, James P. et al. Principles and Applications of Organotransition Metal Chemistry.
Mill Valley, CA: University Science Books, 1987.
• Crabtree, Robert H. The Organometallic Chemistry of the Transition Metals. New York,
NY: John Wiley, 2000.
• E. Stocchi: Industrial Chemistry, Vol -I, Ellis Horwood Ltd. UK.
• P.C. Jain, M. Jain: Engineering Chemistry, Dhanpat Rai & Sons, Delhi.
• B.K. Sharma: Industrial Chemistry, Goel Publishing House, Meerut.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 46 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(6th Semester)
Course No.:CHEMISTRY-C-601-LAB
(Inorganic Chemistry – IV)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 12 hours (spread over two days)

During examination, one Inorganic mixture to be assigned to each student by drawing lots.

1. Qualitative Inorganic Analysis 21 marks

Qualitative analysis of mixtures containing 3 anions and 3 cations. Emphasis should be

given to the understanding of the chemistry of different reactions. The following
radicals are suggested:
- -
CO32-, NO2 , S2-, SO32-, S2O32-, CH3COO-, F-, Cl-, Br-, I-, NO3 , BO33-, C2O42-,
PO43-, NH4+, K+, Pb2+, Cu 2+, Cd 2+, Bi3+, Sn2+, Sb 3+, Fe3+, Al3+, Cr3+, Zn2+, Mn2+,
Co2+, Ni2+, Ba2+, Sr2+, Ca2+, Mg2+
Mixtures should preferably contain one interfering anion,
or insoluble component e.g., BaSO4, SrSO4, PbSO4, CaF2 or Al2O3
or combination of anions e.g. CO32- and SO32-, NO2- and NO3-, Cl- and Br-, Cl-
and I-, B- rand I-, NO3- and Br-, NO3- and I-.

Spot tests should be done whenever possible.

2. Viva – voce 2 marks

3. Regularity in maintenance of Lab Notebook 2 marks

4. Attendance 5 marks

Reference Books:
• Vogel’s Qualitative Inorganic Analysis, Revised by G. Svehla.
• Marr & Rockett Inorganic Preparations.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 47 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY
(Honours)
(6th Semester)
Course No.:CHEMISTRY-C-602
(Organic Chemistry – V)
Spectroscopy, Carbohydrates,Dyes and Polymers
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Objective of this course is to impart knowledge on Application of Spectroscopy (UV-Vis, IR

and NMR), Carbohydrates,Dyes and Polymers (with preparation and applications)

Unit 1: Organic Spectroscopy I

UV Spectroscopy: Types of electronic transitions, λmax, Chromophores and Auxochromes;
Application of Woodward Rules for calculation of λ-max for the following systems: α, β-
unsaturated aldehydes, ketones, carboxylic acids and esters; Conjugated dienes: alicyclic,
homoannular and heteroannular.Applications of UV for identification of simple organic
molecules.
IR Spectroscopy: Fundamental and non-fundamental molecular vibrations; IR absorption
positions of O, N and S containing functional groups; Fingerprint region and its significance;
application in functional group analysis.Applications of IR for identification of simple
organic molecules.

Unit 2: Organic Spectroscopy II

NMR Spectroscopy: Basic principles of Proton Magnetic Resonance, chemical shift and
factors influencing it; Spin – Spin coupling and coupling constant; Interpretation of NMR
spectra of simple compounds.Applications of NMR for identification of simple organic
molecules.

Unit 3: Carbohydrates
Monosaccharides: Constitution and absolute configuration of glucose and fructose, epimers
and anomers, mutarotation, determination of ring size of glucose and fructose, Haworth
projections and conformational structures; Interconversions of aldoses and ketoses; Killiani
Fischer synthesis and Ruff degradation;
Disaccharides – Structure elucidation of sucrose.
Polysaccharides – Elementary treatment of starch and cellulose.
Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 48 of 99
Unit 4: Dyes
Classification, Colour and constitution; Mordant and Vat Dyes; Synthesis and applications of:
Azo dyes – Methyl Orange and Congo Red (mechanism of Diazo Coupling); Triphenyl
Methane Dyes -Malachite Green, Rosaniline and Crystal Violet; Phthalein Dyes –
Phenolphthalein and Fluorescein.

Unit 5: Polymers
Introduction and classification of polymers; Number average molecular weight, Weight
average molecular weight, Degree of polymerization, Polydispersity Index.
Polymerisation reactions- Addition and condensation- Mechanism of cationic, anionic and
free radical addition polymerization; Metallocene-based Ziegler-Natta polymerisation of
alkenes; Preparation and applications of plastics– thermosetting (phenol-formaldehyde,
Polyurethanes) and thermosoftening (PVC, polythene);
Fabrics – natural and synthetic fabrics (acrylic, polyester);
Rubbers – natural and synthetic rubbers: Buna-S, Chloroprene and Neoprene; Vulcanization.

Reference Books:
• Kalsi, P. S. Textbook of Organic Chemistry 1 st Ed., New Age International (P) Ltd. Pub.
• Morrison, R. T. & Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd.
(Pearson Education).
• Billmeyer, F. W. Textbook of Polymer Science, John Wiley & Sons, Inc.
• Gowariker, V. R.; Viswanathan, N. V. & Sreedhar, J. Polymer Science, New Age
International (P) Ltd. Pub.
• Finar, I. L. Organic Chemistry (Volume 2: Stereochemistry and the Chemistry of Natural
Products), Dorling Kindersley (India) Pvt. Ltd. (Pearson Education).
• Graham Solomons, T.W. Organic Chemistry, John Wiley & Sons, Inc.
• Clayden, J.; Greeves, N.; Warren, S.; Wothers, P.; Organic Chemistry, Oxford University
Press.
• Singh, J.; Ali, S.M. & Singh, J. Natural Product Chemistry, Prajati Prakashan (2010).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 49 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
CORE COURSE
CHEMISTRY LAB
(Honours)
(6th Semester)
Course No.:CHEMISTRY-C-602-LAB
(Organic Chemistry – V)
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 12 hours (spread over two days)

During examination, two experiments, to be assigned to each student by drawing lots.

1. The following experiments to be carried out 10.5x2-21 marks

i. Extraction of caffeine from tea leaves.
ii. Preparation of sodium polyacrylate.
iii. Preparation of urea formaldehyde.
iv. Analysis of Carbohydrate: aldoses and ketoses, reducing and non-reducing
sugars.
v. Identification of simple organic compounds by IR spectroscopy and NMR
spectroscopy (Spectra to be provided).
vi. Preparation of methyl orange.

2. Viva – voce 2 marks

3. Regularity in maintenance of Lab Notebook 2 marks

4. Attendance 5 marks

Reference Books:
 Vogel, A.I. Quantitative Organic Analysis, Part 3, Pearson (2012).
 Mann, F.G. & Saunders, B.C. Practical Organic Chemistry, Pearson Education , (2009).
 Furniss, B.S.; Hannaford, A.J.; Smith, P.W.G.; Tatchell, A.R. Practical Organic
Chemistry, 5th Ed., Pearson (2012).
 Ahluwalia, V.K. & Aggarwal, R. Comprehensive Practical Organic Chemistry:
Preparation and Quantitative Analysis,University Press (2000).
 Ahluwalia, V.K. & Dhingra, S. Comprehensive Practical Organic Chemistry:
Qualitative Analysis, University Press (2000).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 50 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
Discipline Specific Elective (DSE) Course
CHEMISTRY
(Honours)
(5th Semester)
Course No.:CHEMISTRY-DSE-501
Analytical Methods in Chemistry
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Unit 1: Qualitative and quantitative aspects of analysis

Sampling, evaluation of analytical data, errors, accuracy and precision, methods of their
expression, normal law of distribution if indeterminate errors, statistical test of data; F, Q and
t test, rejection of data, and confidence intervals.

Unit 2: UV-Visible and IR Spectrometry

Origin of spectra, interaction of radiation with matter, fundamental laws of spectroscopy and
selection rules, validity of Beer-Lambert’s law.
UV-Visible Spectrometry:Basic principles of instrumentation (choice of source,
monochromator and detector) for single and double beam instrument; Basic principles of
quantitative analysis: estimation of metal ions from aqueous solution, geometrical isomers,
keto-enol tautomers. Determination of composition of metal complexes using Job’s method
of continuous variation and mole ratio method.
Infrared Spectrometry: Basic principles of instrumentation (choice of source, monochromator
& detector) for single and double beam instrument; sampling techniques.

Unit 3: Flame Atomic Absorption and Emission Spectrometry

Basic principles of instrumentation (choice of source, monochromator, detector, choice of
flame and Burner designs. Techniques of atomization and sample introduction; Method of
background correction, sources of chemical interferences and their method of removal.
Techniques for the quantitative estimation of trace level of metal ions from water samples.

Unit 4: Thermal and electro-analytical methods of analysis

Theory of thermo-gravimetry (TG), basic principle of instrumentation.Techniques for
quantitative estimation of Ca and Mg from their mixture.
Classification of electro-analytical methods, basic principle of pH metric, potentiometric and
conductometric titrations. Techniques used for the determination of equivalence points.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 51 of 99

Unit 5: Separation techniques
Solvent extraction: Classification, principle and efficiency of the technique. Mechanism of
extraction: extraction by solvation and chelation. Technique of extraction: batch, continuous
and counter current extractions.
Chromatography: Classification, principle and efficiency of the technique. Mechanism of
separation: adsorption, partition & ion exchange. Development of chromatograms: frontal,
elution and displacement methods.Qualitative and quantitative aspects of chromatographic
methods of analysis: TLC and HPLC.

Reference Books:
• Vogel, Arthur I: A Test book of Quantitative Inorganic Analysis (Rev. by G.H. Jeffery and
others) 5th Ed., The English Language Book Society of Longman.
• Willard, Hobert H. et al.: Instrumental Methods of Analysis, 7th Ed., Wardsworth
Publishing Company, Belmont, California, USA, 1988.
• Christian, Gary D; Analytical Chemistry, 6th Ed., John Wiley & Sons, New York, 2004.
• Harris, Daniel C: Exploring Chemical Analysis, Ed. New York, W. H. Freeman, 2001.
• Khopkar, S. M. Basic Concepts of Analytical Chemistry. New Age, International
Publisher, 2009.
• Skoog, D. A. Holler F.J. and Nieman, T.A. Principles of Instrumental Analysis, Thomson
Asia Pvt. Ltd. Singapore.
• Mikes, O. & Chalmes, R.A. Laboratory Hand Book of Chromatographic & Allied
Methods, Elles Harwood Ltd. London.
• Ditts, R.V. Analytical Chemistry – Methods of separation.
• Skoog, Douglas A., West, Donald M., Holler, F. James and Crouch, Stanley R.,
Fundamentals of Analytical Chemistry, 9th Edition.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 52 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
Discipline Specific Elective (DSE) Course
CHEMISTRY LAB
(Honours)
(5th Semester)
Course No.:CHEMISTRY-DSE-501-LAB
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 6 hours (one day)

During examination, two experiments to be assigned to each student by drawing lots12

1. Experiments 10.5x2=21 marks

i) Paper chromatographic separation of Fe3+, Al3+, and Cr3+.

ii) Separation and identification of the monosaccharides present in the given mixture
(glucose & fructose) by paper chromatography. Reporting the Rf values.
iii) Separate a mixture of Sudan yellow and Sudan Red by TLC technique and
identify them on the basis of their Rf values.
iv) Chromatographic separation of the active ingredients of plants, flowers and juices
by TLC
v) Determine the pH of the given aerated drinks fruit juices, shampoos and soaps.
vi) Determination of Na, Ca, Li in cola drinks and fruit juices using flame
photometric techniques.
vii) Analysis of soil: determination of pH of soil, total soluble salt, estimation of
calcium, magnesium, phosphate, nitrate
viii) Separation of metal ions from their binary mixture.
ix) Separation of amino acids from organic acids by ion exchange chromatography.
x) Determination of dissolved oxygen in water.
xi) Determination of chemical oxygen demand (COD).
2. Viva – voce 2 marks
3. Regularity in maintenance of Lab Notebook 2 marks
4. Attendance 5 marks

Reference Books:
• Vogel, Arthur I: A Test book of Quantitative Inorganic Analysis (Rev. by G.H.Jeffery and
others) 5 thEd., The English Language Book Society of Longman.
• Willard, Hobert H. et al.: Instrumental Methods of Analysis, 7thEd., Wardsworth
Publishing Company, Belmont, California, USA, 1988.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 53 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
Discipline Specific Elective (DSE) Course
CHEMISTRY
(Honours)
(5th Semester)
Course No.:CHEMISTRY-DSE-502
Green Chemistry
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Unit 1: Introduction to Green Chemistry

What is Green Chemistry? Need for Green Chemistry. Goals of Green Chemistry.
Limitations/ Obstacles in the pursuit of the goals of Green Chemistry. Green Chemistry in
sustainable development.
Unit 2: Principles of Green Chemistry and Designing a Chemical synthesis
Twelve principles of Green Chemistry with their explanations and examples; Designing a
Green Synthesis using these principles; Prevention of Waste/ byproducts; maximum
incorporation of the materials used in the process into the final products (Atom Economy);
prevention/ minimization of hazardous/ toxic products.
Unit 3: Designing a Chemical synthesis
Designing safer chemicals – different basic approaches to do so; selection of appropriate
auxiliary substances (solvents, separation agents), green solvents, solvent-less processes,
immobilized solvents and ionic liquids; energy requirements for reactions - use of
microwaves, ultrasonic energy; selection of starting materials; avoidance of unnecessary
derivatization –careful use of blocking/protecting groups; use of catalytic reagents (wherever
possible) in preference to stoichiometric reagents;designing of biodegradable products;
prevention of chemical accidents; strengthening/development of analytical techniques to
prevent and minimize the generation of hazardous substances in chemical processes.
Unit 4: Examples of Green Synthesis/ Reactions I
Green Synthesis of the following compounds: adipic acid, catechol, BHT, methyl
methacrylate, urethane, aromatic amines (4-aminodiphenylamine), benzyl bromide,
acetaldehyde, citral, ibuprofen,paracetamol, furfural.
Microwave assisted reactions: Hofmann Elimination, Hydrolysis (of benzyl chloride,
benzamide, n-phenyl benzamide, methylbenzoate to benzole acid), Oxidation (of toluene,
alcohols). Esterification, Fries rearrangement, Orthoester Claisen Rearrangement, Diels-
Alder Reaction, Decarboxylation.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 54 of 99

Unit 5: Examples of Green Synthesis/ Reactions II
Ultrasound assisted reactions: Esterification, saponification, substitution reactions,
Alkylations, oxidation, reduction, coupling reaction, Cannizaro reaction, Strecker synthesis,
Reformatsky reaction.
Selective methylation of active methylene group using dimethylcarbonate: Solid-state
polymerization of amorphous polymers using diphenylcarbonate; Use of “Clayan”, a
nonmetallicoxidative reagent for various reactions; Free Radical Bromination; Role of
Tellurium in organic syntheses.

Reference Books:
• V.K. Ahluwalia & M.R. Kidwai: New Trends in Green Chemistry, Anamalaya Publishers
(2005).
• P.T. Anastas & J.K. Warner: Oxford Green Theory and Practical, University Press (1998).
• A.S. Matlack: Introduction to Green Chemistry, Marcel Dekker (2001).
• M.C. Cann & M.E. Connely: Real-World cases in Green Chemistry, American Chemical
Society, Washington (2000).
• M.A. Ryan & M. Tinnesand, Introduction to Green Chemistry, American Chemical
Society, Washington (2002).

CBCS: B. Sc. (Honours) with CHEMISTRY

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 55 of 99

 Discipline Specific Elective (DSE) Course
CHEMISTRY LAB
(Honours)
(5th Semester)
Course No.:CHEMISTRY-DSE-502-LAB
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 6 hours (one days)

During examination, two experiments (one from each of the Part I and Part II), to be assigned
to each student by drawing lots.12
1. Part I: 10 marks

a. Safer Stating Materials

The Vitamin C clock reaction using Vitamin C tablets, tincture of iodine,
hydrogen peroxide and liquid laundry starch – study of effect of concentration on
clock reaction

b. Using Renewable Resources

Preparation of biodiesel from vegetable oil.

2. Part II:Green Reactions 11 marks

a) Reaction between furan and maleic acid in water and at room temperature rather than
inbenzene and reflux.
b)Extraction of D-limonene from orange peel using liquid CO2 prepared form dry ice.
c) Mechanochemical solvent free synthesis of azomethines
d)Solvent free, microwave assisted one pot synthesis of phthalocyanine complex of copper
(II).
e) Photoreduction of benzophenone to benzopinacol in the presence of sunlight.

3. Viva – voce 2 marks

4. Regularity in maintenance of Lab Notebook 2 marks

5. Attendance 5 marks

Reference Books:
• Anastas, P.T & Warner, J.C. Green Chemistry: Theory and Practice, Oxford University
Press (1998).
• Kirchoff, M. & Ryan, M.A. Greener approaches to undergraduate chemistry experiment.
American Chemical Society, Washington DC (2002).
• Ryan, M.A. Introduction to Green Chemistry, Tinnesand; (Ed), American Chemical
Society, Washington DC (2002).
Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 56 of 99
• Sharma, R.K.; Sidhwani, I.T. & Chaudhari, M.K. I.K. Green Chemistry Experiment: A
monograph International Publishing House Pvt Ltd. New Delhi. Bangalore CISBN 978-
93-81141-55-7 (2013). 56
• Cann, M.C. & Connelly, M. E. Real world cases in Green Chemistry, American Chemical
Society (2008).
• Cann, M. C. & Thomas, P. Real world cases in Green Chemistry, American Chemical
Society (2008).
• Pavia, D. L. Lamponan, G. H. &Kriz, G.S. W B Introduction to organic laboratory.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 57 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
Discipline Specific Elective (DSE) Course
CHEMISTRY
(Honours)
(6th Semester)
Course No.:CHEMISTRY-DSE-601
Inorganic Materials of Industrial Importance
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Unit 1: Silicate Industries

Glass:Glassy state and its properties, classification (silicate and non-
silicateglasses).Manufacture and processing of glass. Composition and properties of the
following types ofglasses: Soda lime glass, lead glass, armoured glass, safety glass,
borosilicate glass, fluorosilicate, coloured glass, photosensitive glass.
Ceramics:Important clays and feldspar, ceramic, their types and manufacture. High
technology ceramics and their applications, superconducting and semiconducting oxides,
fullerenes carbon nanotubes and carbon fibre.
Cements: Classification of cement, ingredients and their role, Manufacture of cement and
thesetting process, quick setting cements.

Unit 2: Fertilizers
Different types of fertilizers. Manufacture of the following fertilizers: Urea, ammonium
nitrate, calcium ammonium nitrate, ammonium phosphates; polyphosphate, superphosphate,
compound and mixed fertilizers, potassium chloride, potassium sulphate.

Unit 3: Surface Coatings

Objectives of coatings surfaces, preliminary treatment of surface, classification of surface
coatings. Paints and pigments-formulation, composition and related properties. Oil paint,
Vehicle, modified oils, Pigments, toners and lakes pigments, Fillers, Thinners, Enamels,
emulsifying agents. Special paints (Heat retardant, Fire retardant, Eco-friendly paint, Plastic
paint), Dyes, Wax polishing, Water and Oil paints, additives, Metallic coatings, metal
spraying and anodizing.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 58 of 99

Unit 4: Batteries
Primary and secondary batteries, battery components and their role, Characteristics ofBattery.
Working of following batteries: Pb acid, Li-Battery, Solid state electrolyte battery. Fuel cells,
Solar cell and polymer cell.

Unit 6: Alloys
Classification of alloys, ferrous and non-ferrous alloys, Specific properties of elements in
alloys. Manufacture of Steel (removal of silicon, decarbonization,demanganization,
desulphurization, dephosphorisation) and surface treatment (argon treatment, heat
treatment,nitriding, carburizing). Composition and properties of different types of steels.

Reference Books:
• E. Stocchi: Industrial Chemistry, Vol-I, Ellis Horwood Ltd. UK.
• R. M. Felder, R. W. Rousseau: Elementary Principles of Chemical Processes,
WileyPublishers, New Delhi.
• W. D. Kingery, H. K. Bowen, D. R. Uhlmann: Introduction to Ceramics, Wiley
Publishers, New Delhi.
• J. A. Kent: Riegel’s Handbook of Industrial Chemistry, CBS Publishers, New Delhi.
• P. C. Jain, M. Jain: Engineering Chemistry, Dhanpat Rai & Sons, Delhi.
• R. Gopalan, D. Venkappayya, S. Nagarajan: Engineering Chemistry, Vikas Publications,
New Delhi.
• B. K. Sharma: Engineering Chemistry, Goel Publishing House, Meerut.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 59 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
Discipline Specific Elective (DSE) Course
CHEMISTRY LAB
(Honours)
(6th Semester)
Course No.:CHEMISTRY-DSE-601-LAB

Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 6 hours (one days)

During examination, one experiment, to be assigned to each student by drawing lots.12

1. Experiments 2421 marks

a. Determination of free acidity in ammonium sulphate fertilizer.

b. Estimation of Calcium in Calcium ammonium nitrate fertilizer.
c. Estimation of phosphoric acid in superphosphate fertilizer.
d. Electroless metallic coatings on ceramic and plastic material.
e. Determination of composition of dolomite (by complexometric titration).
f. Analysis of (Cu, Ni); (Cu, Zn) in alloy or synthetic samples.
g. Analysis of Cement.

2. Viva – voce 2 marks

3. Regularity in maintenance of Lab Notebook 2 marks
4. Attendance 5 marks

Reference Books:
• E. Stocchi: Industrial Chemistry, Vol-I, Ellis Horwood Ltd. UK.
• R. M. Felder, R. W. Rousseau: Elementary Principles of Chemical Processes,
WileyPublishers, New Delhi.
• W. D. Kingery, H. K. Bowen, D. R. Uhlmann: Introduction to Ceramics, Wiley
Publishers, New Delhi.
• J. A. Kent: Riegel’s Handbook of Industrial Chemistry, CBS Publishers, New Delhi.
• P. C. Jain, M. Jain: Engineering Chemistry, Dhanpat Rai & Sons, Delhi.
• R. Gopalan, D. Venkappayya, S. Nagarajan: Engineering Chemistry, Vikas Publications,
New Delhi.
• B. K. Sharma: Engineering Chemistry, Goel Publishing House, Meerut.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 60 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
Discipline Specific Elective (DSE) Course
CHEMISTRY
(Honours)
(6th Semester)
Course No.:CHEMISTRY-DSE-602
Dissertation
(Project Work)
(Credits: 06)
Full Marks: 100 Pass Marks: 40

One project work on inorganic / organic / physical / analytical / biochemical / environmental /

agricultural chemistry. Submission of the project report in bound form and presentation of the
project in front of the external examiner.
Distribution of marks

(a) Internal Assessment (Regularity, timely completion and submission 30 marks

of project report, maintenance of project Dairy)

(b) Project Report (Proper documentation of literature, data, 30 marks

discussion etc. and logical flow of work
undertaken)

(c) Presentation 20 marks

(d) Viva/Defense 20 marks

Total: 100 marks

Guidelines to Project Work:

1. Students shall undertake the project work related to chemistry only under the guidance
of teacher(s) from the department and strict monitoring by the Department. Project
work on inorganic / physical / analytical / biochemical / environmental / agricultural or
others related interface areas may be undertaken. Project work can be experimental,
theoretical or both. The following activities have been outlined as guidelines (not
exhaustive):
(a) Physiochemical studies (pH, conductivity, turbidity, etc.) of different wetlands
(ponds, lakes, river etc.)
(b) Analysis of iron in pond / tube well / river water.
(c) Analysis of Ca2+ / Mg2+ / As3+ / As5+ in soil / water samples.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 61 of 99

 (d) Adulteration detection activities.
(e) Extraction and preliminary characterization of useful chemicals (as far as
possible) from plants.
(f) Solubility, surface tension, and viscosity measurements of some solution of
practical relevance, (cough syrup, soap solution, pesticides, fertilizers,... etc.)
(g) Pollution related activities.
(h) Nutrition related activities, (essential metal detection in food, cereals, pulses,
fruits etc.)
(i) Heavy metal uptake / sequestering activities, (from nature and laboratory based
experiments.

2. Head of the Department must provide the service of a teacher for supervising the
project work of each group. A teacher can guide more than one group, if necessary.

3. No two groups in the same institution are permitted to do project work on the same
problem.

4. The UG level project work is a group activity, maximum number of students being
limited to three. However, each student shall prepare and submit the project report
separately and each student must present the Project Report before the external
examiner during project evaluation.

5. The project report must be hard bound, spiral bound or paper back and each student
must submit a copy of the Project Report to keep in the department.

6. The project report shall be divided as:

Chapter I: Introduction
Chapter II: Review of literature
Chapter III: Scope of the research problem
Chapter IV: Materials and methods
Chapter V: Results and discussion
Chapter VI: Conclusion and Scope of future studies
Chapter VII: References.

Reference Books:
• M. A. Malati, An Investigative, Integrated Approach to Practical Project Work; Mid-Kent
College of Higher/Further Education, UK (October 1999); Imprint: Woodhead Publishing;
ISBN: 978-1-898563-47-1.
• Geoffrey, P. Haydn, S., Practical Inorganic Chemistry: Preparations, reactions and
instrumental methods; Science Paperbacks; (1974); ISBN: 978-0-412-16150-6 (Print) 978-
94-017-2744-0 (Online).
Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 62 of 99
• Dean, J. R., Jones, A. M., Holmes, D., Reed, R., Weyers, J. & Jones, A. (2011) Practical
skills in chemistry. 2nd Ed., Prentice-Hall, Harlow.
• Hibbert, D. B. & Gooding, J. J. (2006) Data analysis for chemistry. Oxford University
Press.
• Topping, J. (1984) Errors of Observation and their Treatment. 4 th Ed., Chapman Hall,
London.
• Harris, D. C. Quantitative Chemical Analysis. 6th Ed., Freeman (2007) Chapters 3-5.
• Levie, R. de, How to use Excel in analytical chemistry and in general scientific data
analysis. Cambridge Univ. Press (2001) 487 pages.
• Chemical Safety Matters – IUPAC – IPCS, Cambridge University Press, 1992.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 63 of 99

 CBCS: B. Sc. (Honours) with CHEMISTRY
Skill Enhancement Course(SEC)
CHEMISTRY
(Honours)
(3rd Semester)
Course No.:CHEMISTRY-SEC-301

Analytical Clinical Biochemistry

Contact Hours: 60; Credits: 04

Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Unit 1: Carbohydrates
Biological importance of carbohydrates. Glycolysis, Alcoholic and Lactic acid fermentations.

Unit 2: Proteins and Enzymes

Proteins: Classification, biological importance; Primary and secondary and tertiary structures
of proteins: α-helix and β- pleated sheets, Isolation, characterization, denaturation of proteins.
Enzymes: Nomenclature, Characteristics (mention of Ribozymes) and Classification; Active
site, Mechanism of enzyme action, Stereospecificity of enzymes, Coenzymes and cofactors,
effect of pH, temperature on enzyme activity, enzyme inhibition.

Unit 2: Lipids and Hormones

Lipids: Classification. Biological importance of triglycerides and phosphoglycerides and
cholesterol; Lipoproteins.
Hormones: Properties, functions and biochemical functions of steroid hormones.

Unit 4: Blood and Urine:

Blood: Composition and functions of blood, blood coagulation. Blood collection and
preservation of samples. Anaemia.
Urine: Collection and preservation of samples. Formation of urine. Composition and
estimation of constituents of normal and pathological urine.

Unit 5: Biochemistry of disease

A diagnostic approach by blood analysis, urine analysis. Interpretation of data for blood
sugar, urea, creatinine, cholesterol and bilirubin.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 64 of 99

Practicals (Demonstrations and Hands-on)
Identification of the following:
1. Carbohydrates.
2. Lipids.
3. Protein by the Biuret reaction.

Reference Books:
• T. G. Cooper: Tool of Biochemistry.
• Keith Wilson and John Walker: Practical Biochemistry.
• Alan H Gowenlock: Varley’s Practical Clinical Biochemistry.
• Thomas M. Devlin: Textbook of Biochemistry.
• Jeremy M. Berg, John L Tymoczko, Lubert Stryer: Biochemistry.
• G. P. Talwar and M Srivastava: Textbook of Biochemistry and Human Biology.
• A. L. Lehninger: Biochemistry.
• O. Mikes, R.A. Chalmers: Laboratory Handbook of Chromatographic Methods

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 65 of 99

 CBCS: B. Sc. with Chemistry
Skill Enhancement Course (SEC)
CHEMISTRY
(4th Semester)
Course No.:CHEMISTRY-SEC-401
Fuel Chemistry

Contact Hours: 60; Credits: 04

Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Unit 1: Review of energy sources (renewable and non-renewable).

Classification of fuels and their calorific value.
Unit 2: Coal: Uses of coal (fuel and nonfuel) in various industries, its composition,
carbonization of coal. Coal gas, producer gas and water gas—composition and
uses. Fractionation of coal tar, uses of coal tar bases chemicals.
Unit 3: Petroleum and Petrochemical Industry: Composition of crude petroleum;
Different types of petroleum products and their applications. Principle and
process of fractional distillation, Cracking – Thermal and catalytic cracking;
Qualitative treatment of non-petroleum fuels- LPG, CNG, LNG, bio-gas,
fuels derived from biomass, fuel from waste; synthetic fuels – gaseous and
liquids.
Unit 4: Petrochemicals: Vinyl acetate, Propylene oxide, Isoprene, Butadiene, Toluene
and its derivatives Xylene.
Unit 5: Lubricants: Classification of lubricants, lubricating oils (conducting and non-
conducting), Solid and semisolid lubricants, synthetic lubricants. Properties of
lubricants – viscosity index, cloud point, pore point.

Reference Books:
• E. Stocchi: Industrial Chemistry, Vol -I, Ellis Horwood Ltd. UK.
• P. C. Jain, M. Jain: Engineering Chemistry, Dhanpat Rai & Sons, Delhi.
• B. K. Sharma: Industrial Chemistry, Goel Publishing House, Meerut.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 66 of 99

 CBCS
TDC SYLLABI

B. Sc. with
CHEMISTRY

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 67 of 99

The following papers (CHEMISTRY-DSC-101 to 104) to be offered
both as:
Discipline Specific Core (DSC) Courses for students of BSc
with Chemistry (Regular)
and
Generic Elective (GE) Courses for students from other
Honours Disciplines

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 68 of 99

 CBCS: B. Sc. with Chemistry
Discipline Specific Core (DSC) Course
CHEMISTRY
(1st Semester)
Course No.:CHEMISTRY-DSC-101/ CHEMISTRY-GE-101
Atomic Structure, Bonding,
General Organic Chemistry and Aliphatic Hydrocarbons

Contact Hours: 60; Credits: 04

Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Section A: Inorganic Chemistry

Unit 1: Atomic Structure

Review of: Bohr’s theory and its limitations, dual behaviour of matter and radiation, de-
Broglie’s relation, Heisenberg Uncertainty principle. Hydrogen atom spectra. Need of a new
approach to Atomic structure.
Quantum mechanics: Time independent Schrodinger equation and meaning of various terms
in it. Significance of  and  2, Schrödinger equation for hydrogen atom. Radial and angular
parts of the hydogenic wave functions (atomic orbitals) and their variations for 1s, 2s, 2p, 3s,
3p and 3d orbitals (Only graphical representation). Radial and angular nodes and their
significance. Radial distribution functions and the concept of the most probable distance with
special reference to 1s and 2s atomic orbitals. Significance of quantum numbers, orbital
angular momentum and quantum numbers ml and ms. Shapes of s, p and d atomic
orbitals, nodal planes. Discovery of spin, spin quantum number (s) and magnetic spin
quantum number (ms).
Rules for filling electrons in various orbitals, Electronic configurations of the atoms. Stability
of half-filled and completely filled orbitals, concept of exchange energy. Relative energies of
atomic orbitals, Anomalous electronic configurations.

Unit 2: Chemical Bonding and Molecular Structure

Ionic Bonding: General characteristics of ionic bonding. Energy considerations in ionic
bonding, lattice energy and solvation energy and their importance in the context of stability
and solubility of ionic compounds. Statement of Born-Landé equation for calculation of
lattice energy, Born-Haber cycle and its applications, polarizing power and polarizability.
Fajan’s rules, ionic character in covalent compounds, bond moment, dipole moment and
percentage ionic character.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 69 of 99

Covalent bonding: VB Approach: Shapes of some inorganic molecules and ions on the basis
of VSEPR and hybridization with suitable examples of linear, trigonal planar, square planar,
tetrahedral, trigonal bipyramidal and octahedral arrangements.
Concept of resonance and resonating structures in various inorganic and organic compounds.

MO Approach: Rules for the LCAO method, bonding and antibonding MOs and their
characteristics for s-s, s-p and p-p combinations of atomic orbitals, nonbonding
combination of orbitals, MO treatment of homonuclear diatomic molecules of 1st and 2nd
periods (including idea of s-p mixing) and heteronuclear diatomic molecules such as CO, NO
and NO+. Comparison of VB and MO approaches.

Section B: Organic Chemistry

Unit 3: Fundamentals of Organic Chemistry

Physical Effects, Electronic Displacements: Inductive Effect, Electromeric Effect, Resonance
and Hyperconjugation. Cleavage of Bonds: Homolysis and Heterolysis.
Structure, shape and reactivity of organic molecules: Nucleophiles and electrophiles.
Reactive Intermediates: Carbocations, Carbanions and free radicals.
Strength of organic acids and bases: Comparative study with emphasis on factors affecting
pK values. Aromaticity: Benzenoids and Hückel’s rule.

Unit 4: Aliphatic Hydrocarbons

Alkanes: (Up to 5 Carbons):
Preparation: Catalytic hydrogenation, Wurtz reaction, Kolbe’s synthesis, from Grignard
reagent.
Reactions: Free radical Substitution: Halogenation.
Alkenes: (Up to 5 Carbons):
Preparation: Elimination reactions: Dehydration of alkenes and dehydrohalogenation of alkyl
halides (Saytzeff’s rule).
Reactions: cis-addition (alk. KMnO4) and trans-addition (bromine), Addition of HX
(Markownikoff’s and anti Markownikoff’s addition), Hydration, Ozonolysis.
Alkynes: (Up to 5 Carbons):
Preparation: Acetylene from CaC2 and conversion into higher alkynes; by dehalogenation of
tetra halides and dehydrohalogenation of vicinaldihalides.
Reactions: formation of metal acetylides, addition of bromine and alkaline KMnO4,
ozonolysis and oxidation with hot alk. KMnO4.

Unit 5: Aromatic Hydrocarbons

Preparation of benzene from phenol, by decarboxylation, from acetylene, from benzene
sulphonic acid.
Reactions benzene: Electrophilic substitution: nitration, halogenation and sulphonation.
Friedel-Craft’s reaction (alkylation and acylation) (up to 4 carbons on benzene). Side chain
oxidation of alkyl benzenes (up to 4 carbons on benzene).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 70 of 99

Reference Books:
• J. D. Lee: A new Concise Inorganic Chemistry, E L. B. S.
• F. A. Cotton & G. Wilkinson: Basic Inorganic Chemistry, John Wiley.
• Douglas, McDaniel and Alexader: Concepts and Models in Inorganic Chemistry, John
Wiley.
• James E. Huheey, Ellen Keiter and Richard Keiter: Inorganic Chemistry: Principles of
Structure and Reactivity, Pearson Publication.
• T. W. Graham Solomon: Organic Chemistry, John Wiley and Sons.
• Peter Sykes: A Guide Book to Mechanism in Organic Chemistry, Orient Longman.
• E. L. Eliel: Stereochemistry of Carbon Compounds, Tata McGraw Hill.
• I. L. Finar: Organic Chemistry (Vol. I & II), E. L. B. S.
• R. T. Morrison & R. N. Boyd: Organic Chemistry, Prentice Hall.
• Arun Bahl and B. S. Bahl: Advanced Organic Chemistry, S. Chand

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 71 of 99

 CBCS: B. Sc. with Chemistry
Discipline Specific Core (DSC) Course
CHEMISTRY LAB
(1st Semester)
Course No.:CHEMISTRY-DSC-101-LAB/ CHEMISTRY-GE-101-LAB
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 6 hours (One day)

During examination, two experiments (one from each of the Section A and Section B), to be
assigned to each student by drawing lots12
Time: 6 hours (One day)

1.Section A: Inorganic 1214 marks

i. Estimation of Fe (II) ions by titrating it with K2Cr2O7 using internal indicator.
ii. Estimation of oxalic acid by titrating it with KMnO4.
iii. Estimation of water of crystallization in Mohr’s salt by titrating with KMnO4.
iv. Estimation of Fe (II) ions by titrating it with KMnO4.
v. Estimation of Cu (II) ions iodometrically using Na2S2O3.

2.Section B: Organic 127 marks

i. Detection of characterized element (N, S, Cl, Br, I) in the given organic compound.
ii. Separation of mixtures by Chromatography: Measure the Rf value in each case
(combination of two compounds to be given)
(a) Identify and separate the components of a given mixture of 2 amino acids
(glycine, aspartic acid, glutamic acid, tyrosine or any other amino acid) by paper
chromatography
(b) Identify and separate the sugars present in the given mixture by paper
chromatography.

3. Viva – voce 2 marks

4. Regularity in maintenance of Lab Notebook 2 marks

5. Attendance 5 marks
Reference Books:
• Vogel’s Qualitative Inorganic Analysis, A. I. Vogel, Prentice Hall, 7th Ed.
• Vogel’s Quantitative Chemical Analysis, A. I. Vogel, Prentice Hall, 6 th Ed.
• Textbook of Practical Organic Chemistry, A. I. Vogel, Prentice Hall, 5 th Ed.
• Practical Organic Chemistry, F. G. Mann. & B. C. Saunders, Orient Longman, 1960.
Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 72 of 99
 CBCS: B. Sc. with Chemistry
Discipline Specific Core (DSC) Course
CHEMISTRY
(2nd Semester)
Course No.:CHEMISTRY-DSC-201 / CHEMISTRY-GE-201
Chemical Energetics, Equilibria and
Functional Organic Chemistry

Contact Hours: 60; Credits: 04

Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Section A: Physical Chemistry

Unit 1: Chemical Energetics

Review of thermodynamics and the Laws of Thermodynamics.
Important principles and definitions of thermochemistry. Concept of standard state and
standard enthalpies of formations, integral and differential enthalpies of solution and dilution.
Calculation of bond energy, bond dissociation energy and resonance energy from
thermochemical data. Variation of enthalpy of a reaction with temperature– Kirchhoff’s
equation.

Unit 2: Equilibria
Chemical Equilibrium: Free energy change in a chemical reaction. Thermodynamic
derivation of the law of chemical equilibrium. Distinction between ΔG and ΔGo, Le
Chatelier’s principle. Relationships between Kp, Kc and Kx for reactions involving ideal
gases.
Ionic Equilibria: Strong, moderate and weak electrolytes, degree of ionization, factors
affecting degree of ionization, ionization constant and ionic product of water. Ionization of
weak acids and bases, pH scale, common ion effect. Salt hydrolysis-calculation of hydrolysis
constant, degree of hydrolysis and pH for different salts. Buffer solutions. Solubility and
solubility product of sparingly soluble salts – applications of solubility product principle.

Section B: Organic Chemistry

Unit 3: Alkyl and Aryl Halides

Alkyl Halides: (Up to 5 Carbons): Types of Nucleophilic Substitution (SN1, SN2 and SNi)
reactions. Preparation: from alkenes and alcohols. Reactions: hydrolysis, nitrite & nitro
formation, nitrile & isonitrile formation. Williamson’s ether synthesis: Elimination vs
substitution.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 73 of 99

Aryl Halides:Preparation: (Chloro, bromo and iodo-benzene case): from phenol, Sandmeyer
& Gattermann reactions. Reactions (Chlorobenzene): Aromatic nucleophilic substitution
(replacement by –OH group) and effect of nitro substituent. Benzyne Mechanism: KNH2/NH3
(or NaNH2/NH3). Reactivity and Relative strength of C-Halogen bond in alkyl, allyl, benzyl,
vinyl and aryl halides.

Unit 4: Alcohols, Phenols and Ethers: (Up to 5 Carbons)

Alcohols: Preparation: Preparation of 1 о, 2о and 3 о alcohols: using Grignard reagent, Ester
hydrolysis, Reduction of aldehydes, ketones, carboxylic acid and esters. Reactions: With
sodium, HX (Lucas test), esterification, oxidation (with PCC, alk. KMnO4, acidic dichromate,
conc. HNO3). Diols: (Up to 6 Carbons) oxidation of diols. Pinacol-Pinacolone rearrangement.
Phenols: (Phenol case): Preparation: Cumene hydroperoxide method, from diazonium salts.
Reactions: Electrophilic substitution: Nitration, halogenation and sulphonation. Reimer-
Tiemann Reaction, Schotten – Baumann Reaction.
Ethers (aliphatic and aromatic):Cleavage of ethers with HI.
Aldehydes and ketones (aliphatic and aromatic): (Formaldehye, acetaldehyde, acetone and
benzaldehyde): Preparation: from acid chlorides and from nitriles. Reactions – Reaction with
HCN, ROH, NaHSO3, NH2-G derivatives. Iodoform test. Aldol Condensation, Cannizzaro’s
Reaction, Wittig Reaction, Benzoin Condensation. Clemensen Reduction and Wolff Kishner
Reduction. Meerwein-Pondorff Verley Reduction.

Unit 5: Stereochemistry & Carbohydrates

Stereochemistry: Concept of chirality (upto two carbon atoms). Geometrical and Optical
isomerism; Enantiomerism, Diastereomerism and Meso compounds. Nomenclature:
cis- trans, R/ S (for up to 2 chiral carbon atoms) and E / Z (for up to two C=C systems).
Carbohydrates: Classification, and General Properties, Glucose and Fructose (open chain and
cyclic structure), Determination of configuration of monosaccharides, absolute configuration
of Glucose and Fructose, Mutarotation, ascending and descending in monosaccharides.
Structure of disacharrides (sucrose, cellobiose, maltose, lactose) and polysacharrides (starch
and cellulose) excluding their structure elucidation.

Reference Books:
 I. L. Finar: Organic Chemistry (Vol. I & II), E. L. B. S.
 R. T. Morrison & R. N. Boyd: Organic Chemistry, Prentice Hall.
 Arun Bahl and B. S. Bahl: Advanced Organic Chemistry, S. Chand.
 G. M. Barrow: Physical Chemistry Tata McGraw-Hill (2007).
 G. W. Castellan: Physical Chemistry 4th Edn. Narosa (2004).
 R. H. Petrucci: General Chemistry 5th Ed. Macmillan Publishing Co.: New York (1985).
 Ball, D. W. Physical Chemistry Thomson Press, India (2007).
 Castellan, G. W. Physical Chemistry 4th Ed. Narosa (2004).

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 74 of 99

 CBCS: B. Sc. with Chemistry
Discipline Specific Core (DSC) Course
CHEMISTRY LAB
(2nd Semester)
Course No.:CHEMISTRY-DSC-201-LAB/ CHEMISTRY-GE-201-LAB
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 6 hours (one day)

During examination, three experiments (one from Section A and two from Section B;
experiment (i) of Section B is compulsory), to be assigned to each student by drawing lots

1. Section A: Physical Chemistry: 12 11 marks

I) Thermochemistry
i. Determination of heat capacity of a calorimeter.
ii. Determination of enthalpy of neutralization of hydrochloric acid with sodium
hydroxide.
iii. Determination of enthalpy of ionization of acetic acid.
iv. Determination of integral enthalpy of solution of salts (KNO3, NH4Cl).
v. Determination of enthalpy of hydration of copper sulphate.
vi. Study of the solubility of benzoic acid in water and determination of ΔH.

II) Ionic equilibria

a) Measurement of pH of different solutions like aerated drinks, fruit juices, shampoos and
soaps (use dilute solutions of soaps and shampoos to prevent damage to the glass electrode)
using pH-meter (at least three different materials to be given to per student per experiment)
and preparation of a comparative document.

b) Preparation of Sodium acetate-acetic acid buffer solutions of different pH (the observed

data to be compared with theoretical values)

c) Preparation of Ammonium chloride-ammonium hydroxide buffer solutions of different pH

(the observed data to be compared with theoretical values)

2. Section B: Organic Chemistry 04 +08 5+5=10 marks

i. Purification of organic compounds by crystallization (from water and alcohol) and
distillation.
ii. Criteria of Purity: Determination of melting and boiling points.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 75 of 99

iii. Organic Preparations: Mechanism of various reactions involved to be discussed.
Recrystallisation, determination of melting point and calculation of quantitative yields
to be done.
(a) Bromination of Phenol/Aniline
(b) Benzoylation of amines/phenols
(c) Oxime and 2, 4-dinitrophenylhydrazone of aldehyde/ketone

3. Viva – voce 2 marks

4. Regularity in maintenance of Lab Notebook 2 marks

5. Attendance 5 marks

Reference Book:
 A. I. Vogel: Textbook of Practical Organic Chemistry, 5 th Ed. Prentice-Hall.
 F. G. Mann & B. C. Saunders, Practical Organic Chemistry, Orient Longman (1960).
 B. D. Khosla, Senior Practical Physical Chemistry, R. Chand & Co.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 76 of 99

 CBCS: B. Sc. with Chemistry
Discipline Specific Core (DSC) Course
CHEMISTRY
(3rd Semester)
Course No.:CHEMISTRY-DSC-301 / CHEMISTRY-GE-301
Solutions, Phase Equilibrium, Conductance, Electrochemistry and
Functional Group Organic Chemistry-II
Contact Hours: 60; Credits: 04
Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Section A: Physical Chemistry

Unit 1: Solutions and Phase Equilibrium

Thermodynamics of ideal solutions: Ideal solutions and Raoult’s law, deviations from
Raoult’s law – non-ideal solutions. Vapour pressure-composition and temperature
composition curves of ideal and non-ideal solutions. Distillation of solutions. Azeotropes.
Partial miscibility of liquids: Critical solution temperature; effect of impurity on partial
miscibility of liquids. Immiscibility of liquids- Principle of steam distillation. Nernst
distribution law and its applications, solvent extraction.
Phases, components and degrees of freedom of a system, criteria of phase equilibrium. Gibbs
Phase Rule. Phase diagrams of one-component systems (water and sulphur).

Unit 2: Conductance and Electrochemistry

Conductivity, equivalent and molar conductivity and their variation with dilution for weak
and strong electrolytes. Kohlrausch’s law of independent migration of ions.
Transference number and its experimental determination using Hittorf and Moving boundary
methods. Ionic mobility. Applications of conductance measurements: determination of degree
of ionization of weak electrolyte, solubility and solubility products of sparingly soluble salts,
ionic product of water, hydrolysis constant of a salt. Conductometric titrations (only acid-
base).
Reversible and irreversible cells. Concept of EMF of a cell. Measurement of EMF of a cell.
Nernst equation and its importance. Types of electrodes. Standard electrode potential.
Electrochemical series. Thermodynamics of a reversible cell, calculation of thermodynamic
properties: ΔG, ΔH and ΔS from EMF data.
Calculation of equilibrium constant from EMF data. Concentration cells with transference
and without transference. Liquid junction potential and salt bridge.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 77 of 99

Section B: Organic Chemistry

Unit 3: Carbonyls (aliphatic and aromatic) and Carboxylic acids

Formaldehyde, acetaldehyde, acetone and benzaldehyde: Preparation: from acid chlorides
and from nitriles. Reactions – Reaction with HCN, ROH, NaHSO3, NH2-G derivatives.
Iodoform test. Aldol Condensation, Cannizzaro’s Reaction, Wittig Reaction, Benzoin
Condensation. Clemensen Reduction and Wolff Kishner Reduction. Meerwein-Pondorff
Verley Reduction.
Carboxylic acids (aliphatic and aromatic): Preparation: Acidic and Alkaline hydrolysis of
esters. Reactions: Hell – Vohlard - Zelinsky Reaction.

Unit 4: Amines
Amines (Aliphatic and Aromatic): (Up to 5 carbons): Preparation: from alkyl halides,
Gabriel’s Phthalimide synthesis, Hofmann Bromamide reaction. Reactions: Hofmann vs.
Saytzeff elimination, Carbylamine test, Hinsberg test, with HNO2, Schotten – Baumann
Reaction. Electrophilic substitution (case aniline): nitration, bromination, sulphonation.

Unit 5: Carbohydrates, Amino Acids, Peptides and Proteins

Carbohydrates: Classification, and General Properties, Glucose and Fructose (open chain and
cyclic structure), Determination of configuration of monosaccharides, absolute configuration
of Glucose and Fructose, Mutarotation, ascending and descending in monosaccharides.
Amino Acids, Peptides and Proteins: Preparation of Amino Acids: Strecker synthesis using
Gabriel’s phthalimide synthesis. Zwitterion, Isoelectric point and Electrophoresis. Reactions
of Amino acids: ester of –COOH group, acetylation of –NH2 group, complexation with Cu2+
ions, ninhydrin test.

Reference Books:
 G. M. Barrow: Physical Chemistry Tata McGraw-Hill (2007).
 G. W. Castellan: Physical Chemistry 4th Ed. Narosa (2004).
 J. C. Kotz, P. M. Treichel, J. R. Townsend, General Chemistry, Cengage
 Learning India Pvt. Ltd.: New Delhi (2009).
 B. H. Mahan: University Chemistry, 3rd Edn. Narosa (1998).
 R. H. Petrucci, General Chemistry, 5th Ed., Macmillan Publishing Co.: New York (1985).
 Morrison, R. T. & Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd.
(Pearson Education).
 Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt. Ltd. (Pearson
Education).
 Finar, I. L. Organic Chemistry (Volume 2), Dorling Kindersley (India) Pvt. Ltd. (Pearson
Education).
 Nelson, D. L. & Cox, M. M. Lehninger’s Principles of Biochemistry 7th Ed., W. H.
Freeman.
 Berg, J. M., Tymoczko, J. L. & Stryer, L. Biochemistry 7 th Ed., W. H. Freeman.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 78 of 99

 CBCS: B. Sc. with Chemistry
Discipline Specific Core (DSC) Course
CHEMISTRY LAB
(3rd Semester)
Course No.:CHEMISTRY-DSC-301-LAB / CHEMISTRY-GE-301-LAB
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 6 hours (one day)

During examination, two experiments (one from each of the Section A and Section B), to be
assigned to each student by drawing lots12

1. Section A: Physical Chemistry: 12 7 marks

I) Phase Equilibria
i. Construction of the phase diagram of a binary system (simple eutectic) using cooling
curves.
ii. Determination of the critical solution temperature and composition of the phenol water
system and study of the effect of impurities on it.
iii. Study of the variation of mutual solubility temperature with concentration for the
phenol water system and determination of the critical solubility temperature.
II) Conductance
i. Determination of cell constant
ii. Perform the following conductometric titrations:
a. Strong acid vs. strong base
b. Weak acid vs. strong base
2. Section B: Organic Chemistry: 12 14 marks
Systematic Qualitative Organic Analysis of Organic Compounds possessing
mono-functional groups (-COOH, phenolic, aldehydic, ketonic, amide, nitro, amines)
and preparation of one derivative.
3. Viva – voce 2 marks
4. Regularity in maintenance of Lab Notebook 2 marks
5. Attendance 5 marks
Reference Books:
• A.I.Vogel: Textbook of Practical Organic Chemistry, Prentice Hall, 5th Ed.
• F. G. Mann & B. C. Saunders: Practical Organic Chemistry, Orient Longman, 1960.
• B. D. Khosla: Senior Practical Physical Chemistry, R. Chand & Co.
• Ahluwalia, V. K. & Aggarwal, R. Comprehensive Practical Organic Chemistry,
Universities Press.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 79 of 99

 CBCS: B. Sc. with Chemistry
Discipline Specific Core (DSC) Course
CHEMISTRY
(4th Semester)
Course No.:CHEMISTRY-DSC-401 / CHEMISTRY-GE-401
Transition metals,Coordination Chemistry,
States of Matter and Chemical Kinetics

Contact Hours: 60; Credits: 04

Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Section A: Inorganic Chemistry

Unit 1: Transition Series Elements (3d series)

General group trends with special reference to electronic configuration, variable valency,
colour, magnetic and catalytic properties, ability to form complexes and stability of various
oxidation states (Latimer diagrams) for Mn, Fe and Cu.
Lanthanoids and actinoids: Electronic configurations, oxidation states, colour, magnetic
properties, lanthanide contraction, separation of lanthanides (ion exchange method only).

Unit 2: Coordination Chemistry

Valence Bond Theory (VBT): Inner and outer orbital complexes of Cr, Fe, Co, Ni and Cu
(coordination numbers 4 and 6).Structural and stereoisomerism in complexes with
coordination numbers 4 and 6.Drawbacks of VBT.
IUPAC (2005)system of nomenclature.
Crystal Field Theory (CFT): Crystal field effect, octahedral symmetry. Crystal field
stabilization energy (CFSE), Crystal field effects for weak and strong fields. Tetrahedral
symmetry.Factors affecting the magnitude of D.Spectrochemical series.Comparison of CFSE
for Oh and Td complexes,Tetragonal distortion of octahedral geometry.

Section B: Physical Chemistry

Unit 3: Gases, Liquids and Solids

Gases: Kinetic Theory of Gases: Postulates of Kinetic Theory of Gases and derivation of the
kinetic gas equation.
Deviation of real gases from ideal behaviour, compressibility factor, causes of deviation. van
der Waals equation of state for real gases. Boyle temperature (derivation not required).
Critical phenomena, critical constants and their calculation from van der Waals equation.
Andrews isotherms of CO2.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 80 of 99

Maxwell Boltzmann distribution laws of molecular velocities and molecular energies
(graphic representation – derivation not required) and their importance.
Temperature dependence of these distributions. Most probable, average and root mean square
velocities (no derivation). Collision number and mean free path of molecules.
Viscosity of gases, effect of temperature/pressure on coefficient of viscosity (qualitative
treatment only).

Unit 4: Liquids and Solids

Liquids: Surface tension and its determination using stalagmometer. Viscosity of a liquid and
determination of coefficient of viscosity using Ostwald viscometer. Effect of temperature on
surface tension and coefficient of viscosity of a liquid (qualitative treatment only)
Solids: Forms of solids. Symmetry elements, unit cells, crystal systems, Bravais lattice types
and identification of lattice planes. Laws of Crystallography - Law of constancy of interfacial
angles, Law of rational indices. Miller indices. Bragg’s law. Structures of NaCl (qualitative
treatment only). Defects in crystals. Glasses and liquid crystals.

Unit 5: Chemical Kinetics

The concept of reaction rates. Effect of temperature, pressure, catalyst and other factors on
reaction rates. Order and molecularity of a reaction. Derivation of integrated rate equations
for zero, first and second order reactions. Half–life of a reaction. General methods for
determination of order of a reaction. Concept of activation energy and its calculation from
Arrhenius equation.
Theories of Reaction Rates: Collision theory and Activated Complex theory of bimolecular
reactions. Comparison of the two theories (qualitative treatment only).

Reference Books:
• G. M. Barrow: Physical Chemistry Tata McGraw-Hill (2007).
• G. W. Castellan: Physical Chemistry 4th Edn. Narosa (2004).
• B. H. Mahan: University Chemistry 3rd Ed. Narosa (1998).
• J. D. Lee: A New Concise Inorganic Chemistry, ELBS.
• F. A. Cotton & G. Wilkinson: Basic Inorganic Chemistry, John Wiley.
• D. F. Shriver and P. W. Atkins: Inorganic Chemistry, OUP.
• Gary Wulfsberg: Inorganic Chemistry, Viva Books Pvt. Ltd.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 81 of 99

 CBCS: B. Sc. with Chemistry
Discipline Specific Core (DSC) Course
CHEMISTRY LAB
(4th Semester)
Course No.:CHEMISTRY-DSC-401-LAB / CHEMISTRY-GE-401-LAB
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 6 hours (one day)

During examination, two experiments (one from each of the Section A and Section B), to be
assigned to each student by drawing lots12
1. Section A: Inorganic Chemistry 12 14 marks
A.Semi-micro qualitative analysis (two anions and two cations and excluding insoluble salts)
out of the following::
Cations: Pb2+, Ag2+, Bi3+, Cu 2+, Cd2+, Sn2+, Fe3+, Al3+, Co2+, Cr3+, Ni2+,
Mn2+, Zn2+, Ba2+, Sr2+, Ca2+, Mg2+, NH4+.
Anions: CO32-, NO2-, NO3-, SO42-, Cl-, Br-, I-, BO33, PO43-.
Spot tests should be done whenever possible.
B. (i) Estimate the amount of nickel present in a given solution as bis(dimethylglyoximato)
nickel(II) or aluminium as oximate in a given solution gravimetrically.
(ii) Determine the composition of the Fe3+-salicylic acid complex solution by Job’s method.
(iii) Estimation of (a) Mg2+ or (b) Zn2+ by complexometric titrations using EDTA.
(iv) Estimation of total hardness of a given sample of water by complexometric titration.
(v) Determination of concentration of Na+ and K+ using Flame Photometry.
2.Section B: Physical Chemistry 127marks
I. Surface tension measurement (use of organic solvents excluded).
Determination of the surface tension of a liquid or a dilute solution using a
stalagmometer.
II. Viscosity measurement (use of organic solvents excluded).
Determination of the relative and absolute viscosity of a liquid or dilute solution using
an Ostwald’s viscometer.
III. Chemical Kinetics
Compare the strengths of HCl and H2SO4 by studying kinetics of hydrolysis of methyl
acetate

3. Viva – voce 2 marks

4. Regularity in maintenance of Lab Notebook 2 marks
5. Attendance 5 marks
Reference Books:
• A. I. Vogel, Qualitative Inorganic Analysis, Prentice Hall, 7th Ed.
• A. I. Vogel, Quantitative Chemical Analysis, Prentice Hall, 6th Ed.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 82 of 99

 CBCS: B. Sc. with Chemistry
Discipline Specific Elective (DSE) Course
CHEMISTRY
(5th Semester)
Course No.:CHEMISTRY-DSE-501
Analytical Methods in Chemistry

Contact Hours: 60; Credits: 04

Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Unit 1: Qualitative and Quantitative aspects of Analysis

Sampling, evaluation of analytical data, errors, accuracy and precision, methods of their
expression, normal law of distribution if indeterminate errors, statistical test of data; F, Q and
t test, rejection of data, and confidence intervals.

Unit 2: UV-Visible and IR Spectrometry

Origin of spectra, interaction of radiation with matter, fundamental laws of spectroscopy and
selection rules, validity of Beer-Lambert’s law.
UV-Visible Spectrometry: Basic principles of instrumentation (choice of source,
monochromator and detector) for single and double beam instrument; Basic principles of
quantitative analysis: estimation of metal ions from aqueous solution, geometrical isomers,
keto-enol tautomers. Determination of composition of metal complexes using Job’s method
of continuous variation and mole ratio method.
Infrared Spectrometry: Basic principles of instrumentation (choice of source, monochromator
& detector) for single and double beam instrument; sampling techniques.

Unit 3: Flame Atomic Absorption and Emission Spectrometry:

Basic principles of instrumentation (choice of source, monochromator, detector, choice of
flame and Burner designs. Techniques of atomization and sample introduction; Method of
background correction, sources of chemical interferences and their method of removal.
Techniques for the quantitative estimation of trace level of metal ions from water samples.

Unit 4: Thermal and Electro-analytical Methods of Analysis:

Theory of thermo-gravimetry (TG), basic principle of instrumentation. Techniques for
quantitative estimation of Ca and Mg from their mixture.
Classification of electro-analytical methods, basic principle of pH metric, potentiometric and
conductometric titrations. Techniques used for the determination of equivalence points.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 83 of 99

Unit 5: Separation Techniques:
Solvent extraction: Classification, principle and efficiency of the technique. Mechanism of
extraction: extraction by solvation and chelation. Technique of extraction: batch, continuous
and counter current extractions.
Chromatography: Classification, principle and efficiency of the technique. Mechanism of
separation: adsorption, partition & ion exchange. Development of chromatograms: frontal,
elution and displacement methods. Qualitative and quantitative aspects of chromatographic
methods of analysis: TLC and HPLC.

Reference Books:
• Vogel, Arthur I: A Test book of Quantitative Inorganic Analysis (Rev. by G.H. Jeffery and
others) 5th Ed., The English Language Book Society of Longman.
• Willard, Hobert H. et al.: Instrumental Methods of Analysis, 7th Ed., Wardsworth
Publishing Company, Belmont, California, USA, 1988.
• Christian, Gary D; Analytical Chemistry, 6th Ed., John Wiley & Sons, New York, 2004.
• Harris, Daniel C: Exploring Chemical Analysis, Ed. New York, W. H. Freeman, 2001.
• Khopkar, S. M. Basic Concepts of Analytical Chemistry. New Age, International
Publisher, 2009.
• Skoog, D. A. Holler F.J. and Nieman, T.A. Principles of Instrumental Analysis, Thomson
Asia Pvt. Ltd. Singapore.
• Mikes, O. & Chalmes, R.A. Laboratory Hand Book of Chromatographic & Allied
Methods, Elles Harwood Ltd. London.
• Ditts, R.V. Analytical Chemistry – Methods of separation.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 84 of 99

 CBCS: B. Sc. with Chemistry
Discipline Specific Elective (DSE) Course
CHEMISTRY LAB
(5th Semester)
Course No.:CHEMISTRY-DSE-501-LAB
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 6 hours (One day)

During examination, two experiments to be assigned to each student by drawing lots.

1. Experiments 24 21 marks
i. Paper chromatographic separation of Fe3+, Al3+, and Cr3+.
ii. Separation and identification of the monosaccharides present in the given mixture
(glucose & fructose) by paper chromatography. Reporting the Rf values.
iii. Separate a mixture of Sudan yellow and Sudan Red by TLC technique and
identify them on the basis of their Rf values.
iv. Chromatographic separation of the active ingredients of plants, flowers and juices
by TLC
v. Determine the pH of the given aerated drinks fruit juices, shampoos and soaps.
vi. Determination of Na, Ca, Li in cola drinks and fruit juices using flame
photometric techniques.
vii. Analysis of soil: determination of pH of soil, total soluble salt, estimation of
calcium, magnesium, phosphate, nitrate
viii. Separation of metal ions from their binary mixture.
ix. Separation of amino acids from organic acids by ion exchange chromatography.
x. Determination of dissolved oxygen in water.
xi. Determination of chemical oxygen demand (COD).
2. Viva – voce 2 marks
3. Regularity in maintenance of Lab Notebook 2 marks
4. Attendance 5 marks

Reference Books:
• Vogel, Arthur I: A Test book of Quantitative Inorganic Analysis (Rev. by G. H. Jeffery
and others) 5th Ed., The English Language Book Society of Longman.
• Willard, Hobert H. et al.: Instrumental Methods of Analysis, 7th Ed., Wardsworth
Publishing Company, Belmont, California, USA, 1988.
• Khopkar, S.M. Basic Concepts of Analytical Chemistry. New Age, International
Publisher, 2009.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 85 of 99

 CBCS: B. Sc. with Chemistry
Discipline Specific Elective (DSE) Course
CHEMISTRY
(6th Semester)
Course No.:CHEMISTRY-DSE-601
Inorganic Materials of Industrial Importance

Contact Hours: 60; Credits: 04

Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Unit 1: Silicate Industries:

Glass: Glassy state and its properties, classification (silicate and non-silicate glasses).
Manufacture and processing of glass. Composition and properties of the following types of
glasses: Soda lime glass, lead glass, armoured glass, safety glass, borosilicate glass,
fluorosilicate, coloured glass, photosensitive glass.
Ceramics: Important clays and feldspar, ceramic, their types and manufacture. High
technology ceramics and their applications, superconducting and semiconducting oxides,
fullerenes carbon nanotubes and carbon fibre.
Cements: Classification of cement, ingredients and their role, Manufacture of cement and the
setting process, quick setting cements.

Unit 2: Fertilizers
Different types of fertilizers. Manufacture of the following fertilizers: Urea, ammonium
nitrate, calcium ammonium nitrate, ammonium phosphates; polyphosphate, superphosphate,
compound and mixed fertilizers, potassium chloride, potassium sulphate.

Unit 3: Surface Coatings

Objectives of coatings surfaces, preliminary treatment of surface, classification of surface
coatings. Paints and pigments-formulation, composition and related properties. Oil paint,
Vehicle, modified oils, Pigments, toners and lakes pigments, Fillers, Thinners, Enamels,
emulsifying agents. Special paints (Heat retardant, Fire retardant, Eco-friendly paint, Plastic
paint), Dyes, Wax polishing, Water and Oil paints, additives, Metallic coatings, metal
spraying and anodizing.

Unit 4: Batteries
Primary and secondary batteries, battery components and their role, Characteristics of
Battery. Working of following batteries: Pb acid, Li-Battery, Solid state electrolyte battery.
Fuel cells, Solar cell and polymer cell.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 86 of 99

Unit 6: Alloys
Classification of alloys, ferrous and non-ferrous alloys, Specific properties of elements in
alloys. Manufacture of Steel (removal of silicon, decarbonization, demanganization,
desulphurization, dephosphorisation) and surface treatment (argon treatment, heat treatment,
nitriding, carburizing). Composition and properties of different types of steels.

Reference Books:
• E. Stocchi: Industrial Chemistry, Vol-I, Ellis Horwood Ltd. UK.
• R. M. Felder, R. W. Rousseau: Elementary Principles of Chemical Processes, Wiley
Publishers, New Delhi.
• W. D. Kingery, H. K. Bowen, D. R. Uhlmann: Introduction to Ceramics, Wiley
Publishers, New Delhi.
• J. A. Kent: Riegel’s Handbook of Industrial Chemistry, CBS Publishers, New Delhi.
• P. C. Jain, M. Jain: Engineering Chemistry, Dhanpat Rai & Sons, Delhi.
• R. Gopalan, D. Venkappayya, S. Nagarajan: Engineering Chemistry, Vikas Publications,
New Delhi.
• B. K. Sharma: Engineering Chemistry, Goel Publishing House, Meerut.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 87 of 99

 CBCS: B. Sc. with Chemistry
Discipline Specific Elective (DSE) Course
CHEMISTRY LAB
(6th Semester)
Course No.:CHEMISTRY-DSE-601-LAB
Practical
Contact Hours: 60; Credits: 02
Full Marks = 30 Pass Marks = 12
Examination Time: 6 hours (One day)

During examination, two experiments to be assigned to each student by drawing lots.

1. Experiments 24 21 marks
a. Determination of free acidity in ammonium sulphate fertilizer.
b. Estimation of Calcium in Calcium ammonium nitrate fertilizer.
c. Estimation of phosphoric acid in superphosphate fertilizer.
d. Electroless metallic coatings on ceramic and plastic material.
e. Determination of composition of dolomite (by complexometric titration).
f. Analysis of (Cu, Ni); (Cu, Zn) in alloy or synthetic samples.
g. Analysis of Cement.
h. Preparation of pigment (zinc oxide).

2. Viva – voce 2 marks

3. Regularity in maintenance of Lab Notebook 2 marks

4. Attendance 5 marks

Reference Books:
• E. Stocchi: Industrial Chemistry, Vol-I, Ellis Horwood Ltd. UK.
• R. M. Felder, R. W. Rousseau: Elementary Principles of Chemical Processes, Wiley
Publishers, New Delhi.
• W. D. Kingery, H. K. Bowen, D. R. Uhlmann: Introduction to Ceramics, Wiley
Publishers, New Delhi.
• J. A. Kent: Riegel’s Handbook of Industrial Chemistry, CBS Publishers, New Delhi.
• P. C. Jain, M. Jain: Engineering Chemistry, Dhanpat Rai & Sons, Delhi.
• R. Gopalan, D. Venkappayya, S. Nagarajan: Engineering Chemistry, Vikas Publications,
New Delhi.
• B. K. Sharma: Engineering Chemistry, Goel Publishing House, Meerut.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 88 of 99

 CBCS: B. Sc. with Chemistry
Skill Enhancement Course (SEC)
CHEMISTRY
(3rd Semester)
Course No.:CHEMISTRY-SEC-301
Analytical Clinical Biochemistry

Contact Hours: 60; Credits: 04

Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Unit 1: Carbohydrates
Biological importance of carbohydrates. Glycolysis, Alcoholic and Lactic acid fermentations.

Unit 2: Proteins and Enzymes

Proteins: Classification, biological importance; Primary and secondary and tertiary structures
of proteins: α-helix and β- pleated sheets, Isolation, characterization, denaturation of proteins.
Enzymes: Nomenclature, Characteristics (mention of Ribozymes) and Classification; Active
site, Mechanism of enzyme action, Stereospecificity of enzymes, Coenzymes and cofactors,
effect of pH, temperature on enzyme activity, enzyme inhibition.

Unit 2: Lipids and Hormones

Lipids: Classification. Biological importance of triglycerides and phosphoglycerides and
cholesterol; Lipoproteins.
Hormones: Properties, functions and biochemical functions of steroid hormones.

Unit 4: Blood and Urine:

Blood: Composition and functions of blood, blood coagulation. Blood collection and
preservation of samples. Anaemia.
Urine: Collection and preservation of samples. Formation of urine. Composition and
estimation of constituents of normal and pathological urine.

Unit 5: Biochemistry of disease

A diagnostic approach by blood analysis, urine analysis. Interpretation of data for blood
sugar, urea, creatinine, cholesterol and bilirubin.

Practicals (Demonstrations and Hands-on)

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 89 of 99
Identification of the following:
1. Carbohydrates.
2. Lipids.
3. Protein by the Biuret reaction.
Reference Books:
• T. G. Cooper: Tool of Biochemistry.
• Keith Wilson and John Walker: Practical Biochemistry.
• Alan H Gowenlock: Varley’s Practical Clinical Biochemistry.
• Thomas M. Devlin: Textbook of Biochemistry.
• Jeremy M. Berg, John L Tymoczko, Lubert Stryer: Biochemistry.
• G. P. Talwar and M Srivastava: Textbook of Biochemistry and Human Biology.
• A. L. Lehninger: Biochemistry.
• O. Mikes, R.A. Chalmers: Laboratory Handbook of Chromatographic Methods

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 90 of 99

 CBCS: B. Sc. with Chemistry
Skill Enhancement Course (SEC)
CHEMISTRY
(6th Semester)
Course No.:CHEMISTRY-SEC-401
Fuel Chemistry

Contact Hours: 60; Credits: 04

Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Unit 1: Review of energy sources (renewable and non-renewable).

Classification of fuels and their calorific value.
Unit 2: Coal: Uses of coal (fuel and nonfuel) in various industries, its composition,
carbonization of coal. Coal gas, producer gas and water gas—composition and
uses. Fractionation of coal tar, uses of coal tar bases chemicals.
Unit 3: Petroleum and Petrochemical Industry: Composition of crude petroleum;
Different types of petroleum products and their applications. Principle and
process of fractional distillation, Cracking – Thermal and catalytic cracking;
Qualitative treatment of non-petroleum fuels- LPG, CNG, LNG, bio-gas,
fuels derived from biomass, fuel from waste; synthetic fuels – gaseous and
liquids.
Unit 4: Petrochemicals: Vinyl acetate, Propylene oxide, Isoprene, Butadiene, Toluene
and its derivatives Xylene.
Unit 5: Lubricants: Classification of lubricants, lubricating oils (conducting and non-
conducting), Solid and semisolid lubricants, synthetic lubricants. Properties of
lubricants – viscosity index, cloud point, pore point.

Reference Books:
• E. Stocchi: Industrial Chemistry, Vol -I, Ellis Horwood Ltd. UK.
• P. C. Jain, M. Jain: Engineering Chemistry, Dhanpat Rai & Sons, Delhi.
• B. K. Sharma: Industrial Chemistry, Goel Publishing House, Meerut.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 91 of 99

 CBCS: B. Sc. with Chemistry
Skill Enhancement Course (SEC)
CHEMISTRY
(5th Semester)
Course No.:CHEMISTRY-SEC-501
Chemistry of Cosmetics and Perfumes

Contact Hours: 60; Credits: 04

Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

A general study including composition and uses of the following:

Unit 1: Hair dye, hair spray, shampoo, suntan lotions, face powder, lipsticks, talcum
powder, nail enamel
Unit 2: Creams (cold, vanishing and shaving creams), antiperspirants and artificial
flavours
Unit 3: Essential oils and their importance in cosmetic industries with reference to
Eugenol, Geraniol, sandalwood oil, eucalyptus, rose oil, 2-phenyl ethyl alcohol,
Jasmone, Civetone, Muscone
Unit 4: Preparation of the following: (any two)
1. Preparation of talcum powder.
2. Preparation of shampoo.
3. Preparation of enamels.
4. Preparation of hair remover.
Unit 5: Preparation of the following: (any two)
1. Preparation of face cream.
2. Preparation of nail polish
3. Preparation of nail polish remover.

Reference Books:
• E. Stocchi: Industrial Chemistry, Vol -I, Ellis Horwood Ltd. UK.
• P. C. Jain, M. Jain: Engineering Chemistry, Dhanpat Rai & Sons, Delhi.
• B. K. Sharma: Industrial Chemistry, Goel Publishing House, Meerut.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 92 of 99

 CBCS: B. Sc. with Chemistry
Skill Enhancement Course (SEC)
CHEMISTRY
(4th Semester)
Course No.:CHEMISTRY-SEC-601
Pesticide Chemistry

Contact Hours: 60; Credits: 04

Full Marks = 70[End Semester Exam (50) Internal Assessment (20)]
Pass Marks = 28 [End Semester Exam (20) Internal Assessment(08)]
(In the End-semester examination, two questions of 10 marks will be set from each unit,
one needs to be answered from each unit)

Unit 1: General Introduction:

General introduction to pesticides (natural and synthetic), History of pesticides, Classification
of pesticides on chemical nature and accordingto target species, Nature of damage and
management of following pests:Public health pests (mosquitoes), Agricultural pests (Boll
worms, sucking pests),Domestic pests (Bed bugs, cockroaches).

Unit 2: Effects:
Benefits and adverse effects of pesticides (natural and synthetic), Action of pesticide on
nervous system, Toxicology of organophosphates, carbamates and organochlorines: signs,
symptoms and medical treatment for poisoning. Pesticides residues, causes of
pesticideresidues in atmosphere, water, soil and their effects.

Unit 3: Formulatons:
Definition, purposeof formulation, brief account& types-synergists and adjuvantsused in
formulations. Conventional formulations: Dry formulations (concept, diluents and carriers
used), Liquid formulations (Concept, true solutions, colloidal solutions and suspentions,
brief account of solution & oil concentrates)

Changing concepts of pesticides:Environmental and user friendly formulation, Suspension

concentrates, Controlled release formulations (CR) - importance, advantages, preparation
of various types of CR, Micro encapsulated formulation. Biopesticides:Definition,
Bacillus thuringiensis, insect viruses and entomopathogenic fungi – characteristics,
mechanism of action and application

Unit 4: Activity:
Structure and mode of action of the followings:
Insecticides: chlorinated hydrocarbons, organophosphates, carbamates. Fungicides:
Carbendazim, Copper oxy chloride, Dithianon, Strobilurin fungicides. Nematicides:
aliphatic halogen compounds, methyl isocyanate liberators..

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 93 of 99

Unit 5: Representative Pesticides:
Synthesis and technical manufacture and uses of representative pesticides in the following
classes:
Organochlorines (DDT, Gammexene,); Organophosphates (Malathion, Parathion);
Carbamates (Carbofuran and carbaryl); Quinones (Chloranil);
Anilides (Alachlor and Butachlor).

Practicals (Demonstrations and Hands-on)

1. To calculate acidity/alkalinity in given sample of pesticide formulations as per BIS
specifications.
2. Preparation of simple organophosphates, phosphonates and thiophosphates

Reference Book:
• R. Cremlyn: Pesticides, John Wiley.

Assam University: Silchar. CBCS ▪ UG ▪ CHEMISTRY Page 94 of 99